DE69029717T2 - Verfahren zur Immobilisierung von Nukleinsäure an einer festen Oberfläche zur Anwendung in Nukleinsäure-Hybridizierungstests - Google Patents

Verfahren zur Immobilisierung von Nukleinsäure an einer festen Oberfläche zur Anwendung in Nukleinsäure-Hybridizierungstests

Info

Publication number
DE69029717T2
DE69029717T2 DE69029717T DE69029717T DE69029717T2 DE 69029717 T2 DE69029717 T2 DE 69029717T2 DE 69029717 T DE69029717 T DE 69029717T DE 69029717 T DE69029717 T DE 69029717T DE 69029717 T2 DE69029717 T2 DE 69029717T2
Authority
DE
Germany
Prior art keywords
nucleic acid
solid surface
immobilizing
acid strand
modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69029717T
Other languages
English (en)
Other versions
DE69029717D1 (de
Inventor
Chander Bahl
Rhonda Lang
Leo Mendoza
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Clinical Diagnostics Inc
Original Assignee
Ortho Diagnostic Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Diagnostic Systems Inc filed Critical Ortho Diagnostic Systems Inc
Publication of DE69029717D1 publication Critical patent/DE69029717D1/de
Application granted granted Critical
Publication of DE69029717T2 publication Critical patent/DE69029717T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit
DE69029717T 1989-11-30 1990-11-29 Verfahren zur Immobilisierung von Nukleinsäure an einer festen Oberfläche zur Anwendung in Nukleinsäure-Hybridizierungstests Expired - Lifetime DE69029717T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/444,031 US5215882A (en) 1989-11-30 1989-11-30 Method of immobilizing nucleic acid on a solid surface for use in nucleic acid hybridization assays

Publications (2)

Publication Number Publication Date
DE69029717D1 DE69029717D1 (de) 1997-02-27
DE69029717T2 true DE69029717T2 (de) 1997-06-05

Family

ID=23763208

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69029717T Expired - Lifetime DE69029717T2 (de) 1989-11-30 1990-11-29 Verfahren zur Immobilisierung von Nukleinsäure an einer festen Oberfläche zur Anwendung in Nukleinsäure-Hybridizierungstests

Country Status (7)

Country Link
US (1) US5215882A (de)
EP (1) EP0435470B1 (de)
AT (1) ATE147860T1 (de)
CA (1) CA2031026A1 (de)
DE (1) DE69029717T2 (de)
GR (1) GR1001043B (de)
HK (1) HK95097A (de)

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Also Published As

Publication number Publication date
GR900100828A (en) 1992-04-17
DE69029717D1 (de) 1997-02-27
ATE147860T1 (de) 1997-02-15
EP0435470B1 (de) 1997-01-15
EP0435470A1 (de) 1991-07-03
GR1001043B (el) 1993-03-31
US5215882A (en) 1993-06-01
HK95097A (en) 1997-08-01
CA2031026A1 (en) 1991-05-31

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Representative=s name: BOEHMERT & BOEHMERT, 28209 BREMEN