DE69107026T2 - Injizierbare galenische retardzubereitung. - Google Patents

Injizierbare galenische retardzubereitung.

Info

Publication number
DE69107026T2
DE69107026T2 DE69107026T DE69107026T DE69107026T2 DE 69107026 T2 DE69107026 T2 DE 69107026T2 DE 69107026 T DE69107026 T DE 69107026T DE 69107026 T DE69107026 T DE 69107026T DE 69107026 T2 DE69107026 T2 DE 69107026T2
Authority
DE
Germany
Prior art keywords
carrier
drug
microspheres
recipient
injectable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69107026T
Other languages
English (en)
Other versions
DE69107026D1 (de
Inventor
Uribe Juan Angeles
Garza Josue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aplicaciones Farmaceuticas SA de CV
Original Assignee
Aplicaciones Farmaceuticas SA de CV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aplicaciones Farmaceuticas SA de CV filed Critical Aplicaciones Farmaceuticas SA de CV
Application granted granted Critical
Publication of DE69107026D1 publication Critical patent/DE69107026D1/de
Publication of DE69107026T2 publication Critical patent/DE69107026T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
DE69107026T 1990-06-14 1991-06-12 Injizierbare galenische retardzubereitung. Expired - Fee Related DE69107026T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9007417A FR2663224B1 (fr) 1990-06-14 1990-06-14 Forme galenique parenterale.
PCT/EP1991/001097 WO1991019485A1 (fr) 1990-06-14 1991-06-12 Forme galenique injectable retardee

Publications (2)

Publication Number Publication Date
DE69107026D1 DE69107026D1 (de) 1995-03-09
DE69107026T2 true DE69107026T2 (de) 1995-08-31

Family

ID=9397599

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69107026T Expired - Fee Related DE69107026T2 (de) 1990-06-14 1991-06-12 Injizierbare galenische retardzubereitung.

Country Status (33)

Country Link
US (1) US5643604A (de)
EP (1) EP0487674B1 (de)
JP (1) JP2690398B2 (de)
KR (1) KR0157438B1 (de)
CN (1) CN1058608C (de)
AT (1) ATE117546T1 (de)
AU (1) AU643540B2 (de)
BG (1) BG61178B1 (de)
BR (1) BR9105782A (de)
CA (1) CA2064861C (de)
CZ (1) CZ286199B6 (de)
DE (1) DE69107026T2 (de)
DK (1) DK0487674T3 (de)
ES (1) ES2068592T3 (de)
FI (1) FI107697B (de)
FR (1) FR2663224B1 (de)
GR (1) GR3015809T3 (de)
HU (1) HU219461B (de)
IE (1) IE69172B1 (de)
IL (1) IL98458A (de)
NO (2) NO920576L (de)
NZ (1) NZ238543A (de)
PH (1) PH30243A (de)
PL (1) PL167177B1 (de)
PT (1) PT97976B (de)
RO (1) RO110198B1 (de)
RU (1) RU2095055C1 (de)
SK (1) SK279867B6 (de)
TN (1) TNSN91047A1 (de)
TW (1) TW205511B (de)
UY (1) UY23239A1 (de)
WO (1) WO1991019485A1 (de)
ZA (1) ZA914549B (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981719A (en) 1993-03-09 1999-11-09 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US6416778B1 (en) 1997-01-24 2002-07-09 Femmepharma Pharmaceutical preparations and methods for their regional administration
US5993856A (en) * 1997-01-24 1999-11-30 Femmepharma Pharmaceutical preparations and methods for their administration
US6287693B1 (en) * 1998-02-25 2001-09-11 John Claude Savoir Stable shaped particles of crystalline organic compounds
GB9819272D0 (en) * 1998-09-03 1998-10-28 Andaris Ltd Microparticles
SI1165044T1 (en) 1999-03-26 2004-10-31 Pozen, Inc. High potency dihydroergotamine compositions
ATE288687T1 (de) * 2001-09-27 2005-02-15 Cognis Deutschland Gmbh Kugelförmige sterinzubereitungen, deren herstellung und verwendung
EP1448228A4 (de) * 2001-10-24 2007-01-24 Marco Pappagallo Behandlung postoperativer schmerzen
MXPA04006017A (es) * 2001-12-20 2005-06-08 Femmepharma Inc Suministro de farmacos por via vaginal.
KR20050086948A (ko) * 2002-12-27 2005-08-30 디오벡스, 인코포레이티드 인슐린으로 인한 저혈당증을 예방하고 조절하기 위한조성물 및 방법
US7655618B2 (en) 2002-12-27 2010-02-02 Diobex, Inc. Compositions and methods for the prevention and control of insulin-induced hypoglycemia
JP2006515026A (ja) * 2003-01-02 2006-05-18 フェムファーマ ホールディング カンパニー， インコーポレイテッド 乳房の疾患および障害の処置のための薬学的調製物
US9173836B2 (en) 2003-01-02 2015-11-03 FemmeParma Holding Company, Inc. Pharmaceutical preparations for treatments of diseases and disorders of the breast
AU2004246870B2 (en) * 2003-06-13 2009-07-23 Skendi Finance Ltd Slow release estradiol-progesterone formulation for contraception and hormone replacement therapy
US7413690B1 (en) 2003-10-29 2008-08-19 The University Of Mississippi Process and apparatus for producing spherical pellets using molten solid matrices
EP1838716B1 (de) 2005-01-05 2011-06-01 Eli Lilly And Company Olanzapinpamoat-dihydrat
WO2007072491A2 (en) * 2005-12-21 2007-06-28 Baskaran Chandrasekar Sustained release pharmaceutical formulation and treatment of ischemic heart disease by administering the same
EA018036B1 (ru) 2006-11-27 2013-05-30 Х. Лундбекк А/С Гетероариламидные производные
CA2674078C (en) * 2006-12-26 2012-03-20 Femmepharma Holding Company, Inc. Topical administration of danazol
CA2721509A1 (en) 2008-04-14 2009-10-22 Posi Visionary Solutions Llp Method and pharmaceutical composition for obtaining the plasmatic progesterone levels required for different therapeutic indications
US20110003000A1 (en) * 2009-07-06 2011-01-06 Femmepharma Holding Company, Inc. Transvaginal Delivery of Drugs
UY33103A (es) 2009-12-15 2011-07-29 Techsphere S A De C V Formulacion farmaceutica parenteral en suspension, de liberacion sostenida, en dosis baja y ultra baja, en terapia hormonal en el sindrome climaterico
CN102753181B (zh) * 2010-01-14 2014-09-17 优麦克里尼穆德公司 具有改进的储存特性和溶解度特性的包含3-β-羟基-5-α-孕烷-20-酮的药物组合物
RU2576236C1 (ru) * 2014-08-22 2016-02-27 Александр Александрович Кролевец Способ получения нанокапсул антибиотиков в агар-агаре
RU2577689C1 (ru) * 2014-08-26 2016-03-20 Александр Александрович Кролевец Способ получения нанокапсул антибиотиков в агар-агаре
RU2578408C1 (ru) * 2014-09-10 2016-03-27 Александр Александрович Кролевец Способ получения нанокапсул алкалоидов
ITUB20153652A1 (it) * 2015-09-16 2017-03-16 Fatro Spa Microsfere contenenti lattoni macrociclici antielminitici

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE744162A (fr) * 1969-01-16 1970-06-15 Fuji Photo Film Co Ltd Procede d'encapsulage
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US3937668A (en) * 1970-07-15 1976-02-10 Ilse Zolle Method for incorporating substances into protein microspheres
DK123067B (da) * 1970-09-25 1972-05-15 Niro Atomizer As Fremgangsmåde til behandling af et pulverformigt, fedtholdigt mælkeprodukt.
JPS5017525A (de) * 1973-06-14 1975-02-24
US3982537A (en) * 1974-12-30 1976-09-28 Louis Bucalo Dynamic implants and method for implanting the same
CA1077842A (en) * 1975-10-09 1980-05-20 Minnesota Mining And Manufacturing Company Albumin medicament carrier system
IT1202370B (it) * 1976-07-12 1989-02-09 Hoffmann La Roche Soluzioni inietabili in cui l'atti vita' emolitica degli agenti di formazione di micelle naturali e' evitata mediante l'aggiunta di lipoidi e relativi prodotti
US4357259A (en) * 1977-08-01 1982-11-02 Northwestern University Method of incorporating water-soluble heat-sensitive therapeutic agents in albumin microspheres
US4244949A (en) * 1978-04-06 1981-01-13 The Population Council, Inc. Manufacture of long term contraceptive implant
US4331654A (en) * 1980-06-13 1982-05-25 Eli Lilly And Company Magnetically-localizable, biodegradable lipid microspheres
US4384975A (en) * 1980-06-13 1983-05-24 Sandoz, Inc. Process for preparation of microspheres
US4349530A (en) * 1980-12-11 1982-09-14 The Ohio State University Implants, microbeads, microcapsules, preparation thereof and method of administering a biologically-active substance to an animal
FR2524312B1 (fr) * 1982-04-01 1985-10-04 Tech Cuir Centre Nouvelles formes de micro-encapsulation de substances medicamenteuses par des couches homogenes de collagene natif
US4492720A (en) * 1983-11-15 1985-01-08 Benjamin Mosier Method of preparing microspheres for intravascular delivery
US4963367A (en) * 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
JPS61174940A (ja) * 1985-01-29 1986-08-06 Oogawara Kakoki Kk ワックス類コーテイング単核状マイクロカプセルおよびその製造方法
US4675173A (en) * 1985-05-08 1987-06-23 Molecular Biosystems, Inc. Method of magnetic resonance imaging of the liver and spleen
IL79407A (en) * 1985-08-01 1991-03-10 Theragenics Corp System and method for delivering insoluble material into a living body
DE3777721D1 (de) * 1986-08-11 1992-04-30 American Cyanamid Co Zusammensetzungen zur parenteralen verabreichung und deren verwendung.
US4837381A (en) * 1986-08-11 1989-06-06 American Cyanamid Company Compositions for parenteral administration and their use
CA1319886C (en) * 1987-02-03 1993-07-06 Alberto Ferro Mixed micelle solutions
US4892734A (en) * 1987-04-06 1990-01-09 Endocon, Inc. Dispensing paste for forming medicinal pellets
DE3851145T2 (de) * 1987-04-06 1994-12-15 Aberlyn Capital Management Par Durch schnellschmelzen hergestellte medizinische implantate.
US4748024A (en) 1987-04-06 1988-05-31 Endocon, Inc. Flash flow fused medicinal implants
AU4369589A (en) * 1988-10-27 1990-05-03 Abbott Laboratories Controlled-release delivery device, method for producing device, and method of using device
US5019400A (en) * 1989-05-01 1991-05-28 Enzytech, Inc. Very low temperature casting of controlled release microspheres
US5085864A (en) * 1989-10-30 1992-02-04 Abbott Laboratories Injectable formulation for lipophilic drugs
FR2663223B1 (fr) * 1990-06-14 1994-12-02 Af Aplicaciones Far Lab Forme galenique parenterale.

Also Published As

Publication number Publication date
IE912018A1 (en) 1991-12-18
FI107697B (fi) 2001-09-28
NO302927B1 (no) 1998-05-11
CA2064861C (fr) 2000-08-01
US5643604A (en) 1997-07-01
IE69172B1 (en) 1996-08-07
CN1057960A (zh) 1992-01-22
NO920576D0 (no) 1992-02-13
KR0157438B1 (ko) 1998-11-16
FR2663224A1 (fr) 1991-12-20
IL98458A (en) 1995-12-31
RU2095055C1 (ru) 1997-11-10
WO1991019485A1 (fr) 1991-12-26
GR3015809T3 (en) 1995-07-31
CA2064861A1 (fr) 1991-12-15
FR2663224B1 (fr) 1995-01-20
BR9105782A (pt) 1992-08-18
HUT61458A (en) 1993-01-28
RO110198B1 (ro) 1995-11-30
PT97976B (pt) 1998-11-30
KR920702212A (ko) 1992-09-03
HU219461B (hu) 2001-04-28
BG61178B1 (bg) 1997-02-28
NZ238543A (en) 1993-08-26
TNSN91047A1 (fr) 1992-10-25
DK0487674T3 (da) 1995-06-26
AU643540B2 (en) 1993-11-18
PH30243A (en) 1997-02-05
TW205511B (de) 1993-05-11
PL290678A1 (en) 1992-06-26
SK279867B6 (sk) 1999-04-13
ZA914549B (en) 1992-03-25
CN1058608C (zh) 2000-11-22
CZ286199B6 (cs) 2000-02-16
CS181591A3 (en) 1992-06-17
JPH05501268A (ja) 1993-03-11
NO920576L (no) 1992-04-08
JP2690398B2 (ja) 1997-12-10
HU9200775D0 (en) 1992-05-28
PT97976A (pt) 1992-04-30
ES2068592T3 (es) 1995-04-16
PL167177B1 (pl) 1995-08-31
ATE117546T1 (de) 1995-02-15
DE69107026D1 (de) 1995-03-09
UY23239A1 (es) 1991-07-12
EP0487674A1 (de) 1992-06-03
AU8066791A (en) 1992-01-07
IL98458A0 (en) 1992-07-15
EP0487674B1 (de) 1995-01-25
FI920661A0 (fi) 1992-02-14

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee