DE69109754T2 - Festsetzung von Biomolekülen durch verstärkte Niederschlagelektrophorese. - Google Patents

Festsetzung von Biomolekülen durch verstärkte Niederschlagelektrophorese.

Info

Publication number
DE69109754T2
DE69109754T2 DE69109754T DE69109754T DE69109754T2 DE 69109754 T2 DE69109754 T2 DE 69109754T2 DE 69109754 T DE69109754 T DE 69109754T DE 69109754 T DE69109754 T DE 69109754T DE 69109754 T2 DE69109754 T2 DE 69109754T2
Authority
DE
Germany
Prior art keywords
biomolecules
fixing
increased precipitation
electrophoresis
precipitation electrophoresis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69109754T
Other languages
English (en)
Other versions
DE69109754D1 (de
Inventor
Kirk Willis Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tecpharma Licensing AG
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE69109754D1 publication Critical patent/DE69109754D1/de
Application granted granted Critical
Publication of DE69109754T2 publication Critical patent/DE69109754T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/002—Electrode membranes
    • C12Q1/003—Functionalisation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/817—Enzyme or microbe electrode
DE69109754T 1990-06-29 1991-06-25 Festsetzung von Biomolekülen durch verstärkte Niederschlagelektrophorese. Expired - Lifetime DE69109754T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/546,101 US5166063A (en) 1990-06-29 1990-06-29 Immobolization of biomolecules by enhanced electrophoretic precipitation

Publications (2)

Publication Number Publication Date
DE69109754D1 DE69109754D1 (de) 1995-06-22
DE69109754T2 true DE69109754T2 (de) 1995-11-02

Family

ID=24178870

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69109754T Expired - Lifetime DE69109754T2 (de) 1990-06-29 1991-06-25 Festsetzung von Biomolekülen durch verstärkte Niederschlagelektrophorese.

Country Status (24)

Country Link
US (1) US5166063A (de)
EP (1) EP0463859B1 (de)
JP (1) JP3100422B2 (de)
KR (1) KR920000921A (de)
CN (1) CN1057672A (de)
AR (1) AR243937A1 (de)
AT (1) ATE122724T1 (de)
AU (1) AU649686B2 (de)
CA (1) CA2045200C (de)
CZ (1) CZ280025B6 (de)
DE (1) DE69109754T2 (de)
DK (1) DK0463859T3 (de)
ES (1) ES2072544T3 (de)
HU (1) HUT60544A (de)
IE (1) IE67131B1 (de)
IL (1) IL98589A (de)
MX (1) MX173121B (de)
MY (1) MY106367A (de)
NO (1) NO912543L (de)
NZ (1) NZ238646A (de)
PT (1) PT98075B (de)
RU (1) RU2068181C1 (de)
YU (1) YU114891A (de)
ZA (1) ZA914807B (de)

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US5632957A (en) 1993-11-01 1997-05-27 Nanogen Molecular biological diagnostic systems including electrodes
US6051380A (en) * 1993-11-01 2000-04-18 Nanogen, Inc. Methods and procedures for molecular biological analysis and diagnostics
US5849486A (en) 1993-11-01 1998-12-15 Nanogen, Inc. Methods for hybridization analysis utilizing electrically controlled hybridization
US6652808B1 (en) 1991-11-07 2003-11-25 Nanotronics, Inc. Methods for the electronic assembly and fabrication of devices
US6048690A (en) * 1991-11-07 2000-04-11 Nanogen, Inc. Methods for electronic fluorescent perturbation for analysis and electronic perturbation catalysis for synthesis
US6569382B1 (en) 1991-11-07 2003-05-27 Nanogen, Inc. Methods apparatus for the electronic, homogeneous assembly and fabrication of devices
US6315953B1 (en) 1993-11-01 2001-11-13 Nanogen, Inc. Devices for molecular biological analysis and diagnostics including waveguides
US6726880B1 (en) 1993-11-01 2004-04-27 Nanogen, Inc. Electronic device for performing active biological operations and method of using same
US6309602B1 (en) 1993-11-01 2001-10-30 Nanogen, Inc. Stacked, reconfigurable system for electrophoretic transport of charged materials
US7172864B1 (en) 1993-11-01 2007-02-06 Nanogen Methods for electronically-controlled enzymatic reactions
US6287517B1 (en) 1993-11-01 2001-09-11 Nanogen, Inc. Laminated assembly for active bioelectronic devices
US6068818A (en) 1993-11-01 2000-05-30 Nanogen, Inc. Multicomponent devices for molecular biological analysis and diagnostics
US7101661B1 (en) 1993-11-01 2006-09-05 Nanogen, Inc. Apparatus for active programmable matrix devices
US6375899B1 (en) 1993-11-01 2002-04-23 Nanogen, Inc. Electrophoretic buss for transport of charged materials in a multi-chamber system
US6331274B1 (en) 1993-11-01 2001-12-18 Nanogen, Inc. Advanced active circuits and devices for molecular biological analysis and diagnostics
US6225059B1 (en) 1993-11-01 2001-05-01 Nanogen, Inc. Advanced active electronic devices including collection electrodes for molecular biological analysis and diagnostics
US6319472B1 (en) 1993-11-01 2001-11-20 Nanogen, Inc. System including functionally separated regions in electrophoretic system
US6254827B1 (en) 1993-11-01 2001-07-03 Nanogen, Inc. Methods for fabricating multi-component devices for molecular biological analysis and diagnostics
US7582421B2 (en) * 1993-11-01 2009-09-01 Nanogen, Inc. Methods for determination of single nucleic acid polymorphisms using a bioelectronic microchip
US6638482B1 (en) 1993-11-01 2003-10-28 Nanogen, Inc. Reconfigurable detection and analysis apparatus and method
US7314708B1 (en) * 1998-08-04 2008-01-01 Nanogen, Inc. Method and apparatus for electronic synthesis of molecular structures
US7857957B2 (en) 1994-07-07 2010-12-28 Gamida For Life B.V. Integrated portable biological detection system
US6403367B1 (en) 1994-07-07 2002-06-11 Nanogen, Inc. Integrated portable biological detection system
US6379897B1 (en) * 2000-11-09 2002-04-30 Nanogen, Inc. Methods for gene expression monitoring on electronic microarrays
US20040086917A1 (en) * 1995-09-27 2004-05-06 Nanogen, Inc. Methods for electronic fluorescent perturbation for analysis and electronic perturbation catalysis for synthesis
US6706473B1 (en) 1996-12-06 2004-03-16 Nanogen, Inc. Systems and devices for photoelectrophoretic transport and hybridization of oligonucleotides
US6060327A (en) 1997-05-14 2000-05-09 Keensense, Inc. Molecular wire injection sensors
US7220550B2 (en) * 1997-05-14 2007-05-22 Keensense, Inc. Molecular wire injection sensors
US6699667B2 (en) 1997-05-14 2004-03-02 Keensense, Inc. Molecular wire injection sensors
NZ502246A (en) * 1997-06-20 2002-10-25 Univ New York Electrospraying solutions of biologically active substances (proteins) on a substrate for mass fabrication of chips and libraries
DE19741715A1 (de) * 1997-09-22 1999-03-25 Hoechst Ag Pentopyranosyl-Nucleosid, seine Herstellung und Verwendung
DE19751658A1 (de) * 1997-11-21 1999-07-29 Wolfbeis Otto S Prof Dr Verfahren zur Bildung lateral organisierter Strukturen auf Trägeroberflächen
FI116099B (fi) 1999-12-08 2005-09-15 Valtion Teknillinen Menetelmä prosessista saadun näytteen analysoimiseksi on-line kapillaarielektroforeesilaitteiston avulla
US7192445B2 (en) * 2000-12-06 2007-03-20 Astra Tech Ab Medical prosthetic devices and implants having improved biocompatibility
US20030153024A1 (en) * 2001-04-19 2003-08-14 Sullivan Brian M Charged bio-molecule/binding agent conjugate for biological capture
AT410805B (de) * 2001-05-29 2003-08-25 Sleytr Uwe B Verfahren zum erzeugen einer schicht funktioneller moleküle
US6814845B2 (en) 2001-11-21 2004-11-09 University Of Kansas Method for depositing an enzyme on an electrically conductive substrate
US7601493B2 (en) * 2002-07-26 2009-10-13 Nanogen, Inc. Methods and apparatus for screening and detecting multiple genetic mutations
US20040074785A1 (en) * 2002-10-18 2004-04-22 Holker James D. Analyte sensors and methods for making them
US20050109622A1 (en) * 2003-11-26 2005-05-26 Peter Peumans Method for controlling electrodeposition of an entity and devices incorporating the immobilized entity
US20050239184A1 (en) * 2004-04-23 2005-10-27 Reiko Ohara Electric driven protein immobilizing module and method
US7828954B2 (en) * 2004-09-21 2010-11-09 Gamida For Life B.V. Electrode based patterning of thin film self-assembled nanoparticles
US7314542B2 (en) * 2004-09-23 2008-01-01 Nanogen, Inc. Methods and materials for optimization of electronic transportation and hybridization reactions
US20080142366A1 (en) * 2006-12-13 2008-06-19 Prabhakar Apparao Tamirisa Incorporation of biomolecules in thin films
GB0818403D0 (en) * 2008-10-08 2008-11-12 Univ Leuven Kath Aqueous electrophoretic deposition
EP2334845A2 (de) * 2008-10-06 2011-06-22 Katholieke Universiteit Leuven K.U. Leuven R&D Funktionelle schichten von biomolekülen und lebenden zellen und neues system zu ihrer herstellung
WO2011066568A1 (en) * 2009-11-30 2011-06-03 Nanoscale Components, Inc. Methods for producing textured electrode based energy storage device
JP2011137651A (ja) * 2009-12-25 2011-07-14 Sharp Corp 標的認識分子および標的認識分子を固定化する方法
TWI450967B (zh) 2009-12-30 2014-09-01 Univ Nat Taiwan Science Tech 均勻之複合式觸媒／酵素結構及其製備方法與應用
CN102192938B (zh) * 2010-03-19 2015-10-21 黄炳照 均匀的复合式触媒/酶结构及其制备方法与应用
ES2763631T3 (es) 2013-01-30 2020-05-29 Nanoscale Components Inc Introducción gradual de litio en el ánodo pre-tratado con litio de una celda electroquímica de iones de litio
CN105831389A (zh) * 2016-02-15 2016-08-10 林淑录 一种鲍鱼蛋白质制品及其制备方法
US10092207B1 (en) 2016-05-15 2018-10-09 Biolinq, Inc. Tissue-penetrating electrochemical sensor featuring a co-electrodeposited thin film comprised of polymer and bio-recognition element
EP3652795A4 (de) 2017-07-10 2021-03-10 Nanoscale Components, Inc. Verfahren zur bildung einer sei-schicht auf einer anode
US11359300B1 (en) * 2021-02-26 2022-06-14 Laxmi Therapeutic Devices, Inc. Electrochemical method for enzyme immobilization on biosensor electrodes
CN117368289B (zh) * 2023-12-07 2024-03-08 广州市赛特检测有限公司 在碳电极表面偶联蛋白适配体的方法、碳电极及电化学免疫传感器

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US3758396A (en) * 1971-08-31 1973-09-11 Research Corp Ition preparation of immobilized enzymemembrane complexes by electrocodepos
US3839175A (en) * 1973-06-28 1974-10-01 Owens Illinois Inc Electrodeposition of enzymes
US4120759A (en) * 1976-08-10 1978-10-17 New Nippon Electric Company, Ltd. Constant current density plating method
US4242096A (en) * 1977-11-14 1980-12-30 Minnesota Mining And Manufacturing Company Immunoassay for antigens
US4245005A (en) * 1979-02-28 1981-01-13 Purdue Research Foundation Pellicular coated support and method
DE3852122T2 (de) * 1987-03-12 1995-04-27 Japan Government Immobilisierung von biofunktionellem material, daraus erzeugtes element und massnahme zu dessen verwendung.
DE3888767T2 (de) * 1987-03-13 1994-08-04 Japan Government Methode zur Erzeugung einer Biomikroelektrode.
EP0353844A1 (de) * 1988-07-06 1990-02-07 Imperial Chemical Industries Plc Beschichtungsverfahren und Zusammensetzung
EP0350451A3 (de) * 1988-07-08 1991-03-27 Ciba-Geigy Ag Verfahren zur Herstellung von elektroaktiven Langmuir-Blodgett Schichtsystemen

Also Published As

Publication number Publication date
KR920000921A (ko) 1992-01-29
EP0463859A3 (en) 1993-05-12
NO912543L (no) 1991-12-30
JP3100422B2 (ja) 2000-10-16
CN1057672A (zh) 1992-01-08
EP0463859A2 (de) 1992-01-02
ATE122724T1 (de) 1995-06-15
JPH04331362A (ja) 1992-11-19
IE912284A1 (en) 1992-01-01
DK0463859T3 (da) 1995-07-10
HU912199D0 (en) 1991-12-30
DE69109754D1 (de) 1995-06-22
CS192791A3 (en) 1992-02-19
IE67131B1 (en) 1996-03-06
CZ280025B6 (cs) 1995-09-13
IL98589A (en) 1997-06-10
NZ238646A (en) 1994-04-27
MX173121B (es) 1994-02-01
PT98075B (pt) 1998-11-30
MY106367A (en) 1995-05-30
CA2045200A1 (en) 1991-12-30
AU649686B2 (en) 1994-06-02
ES2072544T3 (es) 1995-07-16
AR243937A1 (es) 1993-09-30
YU114891A (sh) 1994-01-20
PT98075A (pt) 1993-06-30
AU7939191A (en) 1992-01-02
US5166063A (en) 1992-11-24
NO912543D0 (no) 1991-06-27
IL98589A0 (en) 1992-07-15
EP0463859B1 (de) 1995-05-17
HUT60544A (en) 1992-09-28
CA2045200C (en) 2000-05-30
ZA914807B (en) 1993-02-24
RU2068181C1 (ru) 1996-10-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: DISETRONIC LICENSING AG, BURGDORF, CH

8328 Change in the person/name/address of the agent

Representative=s name: DERZEIT KEIN VERTRETER BESTELLT