DE69121885T2 - Durch körperliche aktivität gesteuerte vorrichtung zur iontophoretischen verabreichung von medikamenten - Google Patents

Durch körperliche aktivität gesteuerte vorrichtung zur iontophoretischen verabreichung von medikamenten

Info

Publication number
DE69121885T2
DE69121885T2 DE69121885T DE69121885T DE69121885T2 DE 69121885 T2 DE69121885 T2 DE 69121885T2 DE 69121885 T DE69121885 T DE 69121885T DE 69121885 T DE69121885 T DE 69121885T DE 69121885 T2 DE69121885 T2 DE 69121885T2
Authority
DE
Germany
Prior art keywords
physical activity
iontophoretic administration
drugs controlled
drugs
controlled
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69121885T
Other languages
English (en)
Other versions
DE69121885D1 (de
Inventor
Gary Lattin
Rama Padmanabhan
Michael Grace
Paul Sorenson
Joseph Phipps
Larry Mcnichols
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Priority claimed from PCT/US1991/002160 external-priority patent/WO1991015261A1/en
Application granted granted Critical
Publication of DE69121885D1 publication Critical patent/DE69121885D1/de
Publication of DE69121885T2 publication Critical patent/DE69121885T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
DE69121885T 1990-03-30 1991-03-29 Durch körperliche aktivität gesteuerte vorrichtung zur iontophoretischen verabreichung von medikamenten Expired - Lifetime DE69121885T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US50242290A 1990-03-30 1990-03-30
US07/671,267 US5213568A (en) 1990-03-30 1991-03-18 Activity controlled electrotransport drug delivery device
PCT/US1991/002160 WO1991015261A1 (en) 1990-03-30 1991-03-29 Activity controlled electrotransport drug delivery device

Publications (2)

Publication Number Publication Date
DE69121885D1 DE69121885D1 (de) 1996-10-10
DE69121885T2 true DE69121885T2 (de) 1997-03-20

Family

ID=27054150

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69121885T Expired - Lifetime DE69121885T2 (de) 1990-03-30 1991-03-29 Durch körperliche aktivität gesteuerte vorrichtung zur iontophoretischen verabreichung von medikamenten

Country Status (8)

Country Link
US (1) US5213568A (de)
EP (1) EP0522062B1 (de)
JP (1) JP3300953B2 (de)
AT (1) ATE142116T1 (de)
AU (1) AU649439B2 (de)
CA (1) CA2079007C (de)
DE (1) DE69121885T2 (de)
FI (1) FI111131B (de)

Families Citing this family (103)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5499967A (en) * 1992-02-27 1996-03-19 Societe Anonyme Dite: Laboratoires D'hygiene Societe Anonyme Dite: Et De Dietetique (L.H.D.) Transdermal drug delivery device with waveshape generator
US5427585A (en) * 1993-03-29 1995-06-27 Bettinger; David S. On-demand iontophoretic system
US5508030A (en) * 1993-08-05 1996-04-16 Bierman; Howard R. Creating new capillary blood pools for practicing bidirectional medicine
US5635204A (en) * 1994-03-04 1997-06-03 Montefiore Medical Center Method for transdermal induction of anesthesia, analgesia or sedation
US7027859B1 (en) * 1994-09-26 2006-04-11 Alza Corporation Electrotransport delivery device having improved safety and reduced abuse potential
IE960312A1 (en) * 1995-06-02 1996-12-11 Alza Corp An electrotransport delivery device with voltage boosting¹circuit
SE9601528D0 (sv) 1996-04-23 1996-04-23 Pharmacia Ab Transdermally administered dextromethorphan as antitissue agent
US6047208A (en) * 1997-08-27 2000-04-04 Becton, Dickinson And Company Iontophoretic controller
WO1999018797A1 (en) 1997-10-09 1999-04-22 Emory University Method and devices for transdermal delivery of lithium
EP1039950A1 (de) 1997-12-16 2000-10-04 Alza Corporation Regler mit künstlicher last zur gewährleistung einer regelmässigen verabreichung
ES2281940T3 (es) 1997-12-17 2007-10-01 Alza Corporation Iontoforesis con ajuste programado de la corriente electrica.
US6154668A (en) * 1998-08-06 2000-11-28 Medtronics Inc. Ambulatory recorder having a real time and non-real time processors
US6141574A (en) * 1998-08-06 2000-10-31 Medtronic, Inc. Ambulatory recorder having sliding period switches
US6115622A (en) * 1998-08-06 2000-09-05 Medtronic, Inc. Ambulatory recorder having enhanced sampling technique
US6200264B1 (en) 1998-08-06 2001-03-13 Medtronic Inc. Ambulatory recorder having wireless data transfer with a multi-plane lens
US6077223A (en) * 1998-08-06 2000-06-20 Medtronic, Inc. Ambulatory recorder having control screen to present dual interface for dual users
US6014578A (en) * 1998-08-06 2000-01-11 Meotronic, Inc. Ambulatory recorder having method of configuring size of data subject to loss in volatile memory
US6142938A (en) * 1998-08-06 2000-11-07 Medtronic Inc. Ambulatory data recorder having ergonomically shaped housing
US6128520A (en) * 1998-08-06 2000-10-03 Medtronic, Inc. Ambulatory recorder having volatile and non-volatile memories
US6119029A (en) * 1998-08-06 2000-09-12 Medtronic, Inc. Ambulatory recorder having splash resistant sensor ports
US6532386B2 (en) 1998-08-31 2003-03-11 Johnson & Johnson Consumer Companies, Inc. Electrotransort device comprising blades
US6245013B1 (en) 1998-12-14 2001-06-12 Medtronic, Inc. Ambulatory recorder having synchronized communication between two processors
ATE290902T1 (de) * 1999-04-16 2005-04-15 Johnson & Johnson Consumer Vorrichtung zur iontophoretischen verabreichung von medikamenten mit internen sensoren
US6516749B1 (en) * 1999-06-18 2003-02-11 Salasoft, Inc. Apparatus for the delivery to an animal of a beneficial agent
US6890553B1 (en) 1999-07-08 2005-05-10 Johnson & Johnson Consumer Companies, Inc. Exothermic topical delivery device
AU6076200A (en) 1999-07-08 2001-01-30 Johnson & Johnson Consumer Companies, Inc. Exothermic bandage
US7113821B1 (en) 1999-08-25 2006-09-26 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery
US7133717B2 (en) * 1999-08-25 2006-11-07 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery and diagnostic sampling
CA2400325A1 (en) 2000-02-18 2001-08-23 University Of Utah Research Foundation Methods for delivering agents using alternating current
WO2001060448A1 (en) 2000-02-18 2001-08-23 University Of Utah Research Foundation Methods for extracting substances using alternating current
US7404815B2 (en) * 2000-05-01 2008-07-29 Lifescan, Inc. Tissue ablation by shear force for sampling biological fluids and delivering active agents
US7137975B2 (en) * 2001-02-13 2006-11-21 Aciont, Inc. Method for increasing the battery life of an alternating current iontophoresis device using a barrier-modifying agent
CA2464949A1 (en) * 2001-10-24 2003-05-01 Daniela Mavor Device and method for controlled delivery of active substance into the skin
US6638241B2 (en) * 2002-01-03 2003-10-28 Israel Yerushalmy Apparatus for treating bruxism
US10173008B2 (en) 2002-01-29 2019-01-08 Baxter International Inc. System and method for communicating with a dialysis machine through a network
US8775196B2 (en) 2002-01-29 2014-07-08 Baxter International Inc. System and method for notification and escalation of medical data
US8234128B2 (en) 2002-04-30 2012-07-31 Baxter International, Inc. System and method for verifying medical device operational parameters
US7596407B2 (en) 2004-03-26 2009-09-29 Solvay Pharmaceuticals, B.V. Transdermal iontophoretic delivery of piperazinyl-2(3H)-benzoxazolone compounds
EP1595542A1 (de) * 2004-03-26 2005-11-16 Solvay Pharmaceuticals B.V. Transdermale iontophoretische Verabreichung von Piperazinyl-2(3H)-benzoxazolon-Verbindungen
US7519409B2 (en) * 2005-12-29 2009-04-14 Medtronic, Inc. Implantable cell/tissue-based biosensing device
JP5681362B2 (ja) 2006-03-14 2015-03-04 ユニバーシティー オブ サザン カリフォルニア 治療剤の送達のためのｍｅｍｓデバイス
JP5241714B2 (ja) 2006-07-07 2013-07-17 プロテウス デジタル ヘルス， インコーポレイテッド スマートな非経口送達システム
US9220837B2 (en) 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
US8622991B2 (en) * 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
KR20090128499A (ko) 2007-03-19 2009-12-15 인슐린 메디컬 엘티디 약물 전달 장치
WO2009081262A1 (en) 2007-12-18 2009-07-02 Insuline Medical Ltd. Drug delivery device with sensor for closed-loop operation
EP2211974A4 (de) 2007-10-25 2013-02-27 Proteus Digital Health Inc Informationssystem für flüssigkeitsüberströmkanal
US8419638B2 (en) 2007-11-19 2013-04-16 Proteus Digital Health, Inc. Body-associated fluid transport structure evaluation devices
MX364408B (es) 2007-12-20 2019-04-25 Univ Southern California Aparatos y metodos para suministrar agentes terapeuticos.
US20110160640A1 (en) * 2008-01-18 2011-06-30 Yanaki Jamal S Operation management of active transdermal medicament patch
US8862223B2 (en) * 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
US8337404B2 (en) 2010-10-01 2012-12-25 Flint Hills Scientific, Llc Detecting, quantifying, and/or classifying seizures using multimodal data
US8571643B2 (en) 2010-09-16 2013-10-29 Flint Hills Scientific, Llc Detecting or validating a detection of a state change from a template of heart rate derivative shape or heart beat wave complex
US8382667B2 (en) 2010-10-01 2013-02-26 Flint Hills Scientific, Llc Detecting, quantifying, and/or classifying seizures using multimodal data
WO2009137785A2 (en) 2008-05-08 2009-11-12 Replenish Pumps, Llc Drug-delivery pumps and methods of manufacture
US9849238B2 (en) 2008-05-08 2017-12-26 Minipumps, Llc Drug-delivery pump with intelligent control
WO2009137780A2 (en) 2008-05-08 2009-11-12 Replenish Pumps, Llc Implantable pumps and cannulas therefor
US10089443B2 (en) 2012-05-15 2018-10-02 Baxter International Inc. Home medical device systems and methods for therapy prescription and tracking, servicing and inventory
US8057679B2 (en) 2008-07-09 2011-11-15 Baxter International Inc. Dialysis system having trending and alert generation
US8554579B2 (en) 2008-10-13 2013-10-08 Fht, Inc. Management, reporting and benchmarking of medication preparation
CN102245137A (zh) 2008-11-07 2011-11-16 茵苏莱恩医药有限公司 用于药物递送的装置和方法
US20110105952A1 (en) * 2009-10-30 2011-05-05 Seventh Sense Biosystems, Inc. Relatively small devices applied to the skin, modular systems, and methods of use thereof
US9041541B2 (en) 2010-01-28 2015-05-26 Seventh Sense Biosystems, Inc. Monitoring or feedback systems and methods
US9033898B2 (en) 2010-06-23 2015-05-19 Seventh Sense Biosystems, Inc. Sampling devices and methods involving relatively little pain
US20100256524A1 (en) 2009-03-02 2010-10-07 Seventh Sense Biosystems, Inc. Techniques and devices associated with blood sampling
EP2467797B1 (de) 2009-08-18 2017-07-19 MiniPumps, LLC Elektrolytische arzneimittelverabreichungspumpe mit adaptiver steuerung
EP2473226A1 (de) * 2009-09-04 2012-07-11 Minipumps LLC Hautpflaster mit pumpe für subkutane wirkstofffreisetzung
EP2493537B1 (de) * 2009-10-30 2017-12-06 Seventh Sense Biosystems, Inc. Systeme und verfahren zur behandlung, desinfektion und/oder abschirmung der haut oder von auf der haut angebrachten vorrichtungen
AU2011210648B2 (en) 2010-02-01 2014-10-16 Otsuka Pharmaceutical Co., Ltd. Data gathering system
US8332020B2 (en) 2010-02-01 2012-12-11 Proteus Digital Health, Inc. Two-wrist data gathering system
US8649871B2 (en) 2010-04-29 2014-02-11 Cyberonics, Inc. Validity test adaptive constraint modification for cardiac data used for detection of state changes
US8831732B2 (en) 2010-04-29 2014-09-09 Cyberonics, Inc. Method, apparatus and system for validating and quantifying cardiac beat data quality
US8562536B2 (en) 2010-04-29 2013-10-22 Flint Hills Scientific, Llc Algorithm for detecting a seizure from cardiac data
ES2561824T3 (es) 2010-07-16 2016-03-01 Seventh Sense Biosystems, Inc. Ambiente a baja presión para dispositivos de transferencia de fluidos
US20130158482A1 (en) 2010-07-26 2013-06-20 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
US8641646B2 (en) 2010-07-30 2014-02-04 Cyberonics, Inc. Seizure detection using coordinate data
WO2012021801A2 (en) * 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
US8684921B2 (en) 2010-10-01 2014-04-01 Flint Hills Scientific Llc Detecting, assessing and managing epilepsy using a multi-variate, metric-based classification analysis
WO2012064802A1 (en) 2010-11-09 2012-05-18 Seventh Sense Biosystems, Inc. Systems and interfaces for blood sampling
US8827930B2 (en) * 2011-01-10 2014-09-09 Bioguidance Llc System and method for patient monitoring
US9504390B2 (en) 2011-03-04 2016-11-29 Globalfoundries Inc. Detecting, assessing and managing a risk of death in epilepsy
US8428709B1 (en) 2012-06-11 2013-04-23 Incline Therapeutics, Inc. Current control for electrotransport drug delivery
US8428708B1 (en) 2012-05-21 2013-04-23 Incline Therapeutics, Inc. Self-test for analgesic product
US9498162B2 (en) 2011-04-25 2016-11-22 Cyberonics, Inc. Identifying seizures using heart data from two or more windows
EP2702406B1 (de) 2011-04-29 2017-06-21 Seventh Sense Biosystems, Inc. Plasma- oder serumherstellung und entfernung von flüssigkeiten bei reduziertem druck
EP2701598A1 (de) 2011-04-29 2014-03-05 Seventh Sense Biosystems, Inc. Systeme und verfahren zur flüssigkeitsentnahme aus einer person
KR102237667B1 (ko) 2011-04-29 2021-04-12 세븐쓰 센스 바이오시스템즈, 인크. 유체들의 전달 및/또는 수용
US9402550B2 (en) 2011-04-29 2016-08-02 Cybertronics, Inc. Dynamic heart rate threshold for neurological event detection
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
US9681836B2 (en) 2012-04-23 2017-06-20 Cyberonics, Inc. Methods, systems and apparatuses for detecting seizure and non-seizure states
US10448839B2 (en) 2012-04-23 2019-10-22 Livanova Usa, Inc. Methods, systems and apparatuses for detecting increased risk of sudden death
US10552577B2 (en) 2012-08-31 2020-02-04 Baxter Corporation Englewood Medication requisition fulfillment system and method
EP2911641B1 (de) 2012-10-26 2018-10-17 Baxter Corporation Englewood Verbesserte arbeitsstation für medizinische dosiszubereitung
SG11201503190RA (en) 2012-10-26 2015-05-28 Baxter Corp Englewood Improved image acquisition for medical dose preparation system
US10220211B2 (en) 2013-01-22 2019-03-05 Livanova Usa, Inc. Methods and systems to diagnose depression
JP2016518883A (ja) * 2013-03-15 2016-06-30 プロメセオン ファーマ，エルエルシー 化合物の経皮送達用のデバイス、システム、および方法
EP3161778A4 (de) 2014-06-30 2018-03-14 Baxter Corporation Englewood Verwalteter austausch medizinischer informationen
US11107574B2 (en) 2014-09-30 2021-08-31 Baxter Corporation Englewood Management of medication preparation with formulary management
US11575673B2 (en) 2014-09-30 2023-02-07 Baxter Corporation Englewood Central user management in a distributed healthcare information management system
WO2016090091A1 (en) 2014-12-05 2016-06-09 Baxter Corporation Englewood Dose preparation data analytics
EP3265989A4 (de) 2015-03-03 2018-10-24 Baxter Corporation Englewood Pharmaziearbeitsflussverwaltung mit integrierten alarmen
CA2985719C (en) 2015-06-25 2024-03-26 Gambro Lundia Ab Medical device system and method having a distributed database
WO2018114346A1 (en) 2016-12-21 2018-06-28 Gambro Lundia Ab Medical device system including information technology infrastructure having secure cluster domain supporting external domain

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3618601A (en) * 1969-10-16 1971-11-09 Thatcher W Richardson Iontophoresis unit
US4146029A (en) * 1974-04-23 1979-03-27 Ellinwood Jr Everett H Self-powered implanted programmable medication system and method
GB1553289A (en) * 1975-05-23 1979-09-26 Bacchelli S Instrument for measuring body resistance
US4141359A (en) * 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US4292968A (en) * 1979-11-26 1981-10-06 Sybron Corporation Electric supply for ion therapy
US4406658A (en) * 1981-03-06 1983-09-27 Medtronic, Inc. Iontophoretic device with reversible polarity
US4428378A (en) * 1981-11-19 1984-01-31 Medtronic, Inc. Rate adaptive pacer
US4704119A (en) * 1983-02-03 1987-11-03 Alza Corporation Method comprising transdermal and buccal treatment of angina
US4639244A (en) * 1983-05-03 1987-01-27 Nabil I. Rizk Implantable electrophoretic pump for ionic drugs and associated methods
US4808152A (en) * 1983-08-18 1989-02-28 Drug Delivery Systems Inc. System and method for controlling rate of electrokinetic delivery of a drug
WO1986007269A1 (en) * 1985-06-10 1986-12-18 Drug Delivery Systems Inc. Programmable control and mounting system for transdermal drug applicator
FR2562800A1 (fr) * 1984-04-11 1985-10-18 Fournier Laboratoires Dispositif pour l'administration percutanee de medicaments
US4702732A (en) * 1984-12-24 1987-10-27 Trustees Of Boston University Electrodes, electrode assemblies, methods, and systems for tissue stimulation and transdermal delivery of pharmacologically active ligands
US4860751A (en) * 1985-02-04 1989-08-29 Cordis Corporation Activity sensor for pacemaker control
US4886489A (en) * 1986-03-19 1989-12-12 Jacobsen Stephen C Flow-through methods and apparatus for iontophoresis application of medicaments at a controlled pH
US4725263A (en) * 1986-07-31 1988-02-16 Medtronic, Inc. Programmable constant current source transdermal drug delivery system
US4822334A (en) * 1986-12-04 1989-04-18 Robert Tapper Electrical dosimetry control system
EP0313638A4 (de) * 1987-05-15 1989-06-14 Martin H Newman Arzneimittelverabreichungssystem durch inophorese.
AU615188B2 (en) * 1987-05-28 1991-09-26 Drug Delivery Systems Inc. Pulsating transdermal drug delivery system
JPS6456060A (en) * 1987-08-27 1989-03-02 Hayashibara Takeshi Low frequency medical treatment device
US4942883A (en) * 1987-09-29 1990-07-24 Newman Martin H Drug delivery device

Also Published As

Publication number Publication date
FI924376A (fi) 1992-09-29
US5213568A (en) 1993-05-25
AU7586891A (en) 1991-10-30
FI924376A0 (fi) 1992-09-29
JPH05508558A (ja) 1993-12-02
CA2079007C (en) 2001-08-07
CA2079007A1 (en) 1991-10-01
AU649439B2 (en) 1994-05-26
EP0522062A1 (de) 1993-01-13
EP0522062B1 (de) 1996-09-04
ATE142116T1 (de) 1996-09-15
FI111131B (fi) 2003-06-13
DE69121885D1 (de) 1996-10-10
JP3300953B2 (ja) 2002-07-08

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