DE69124365D1 - Mittels ultraschall gesteigerte verabreichung von materialien durch die haut - Google Patents

Mittels ultraschall gesteigerte verabreichung von materialien durch die haut

Info

Publication number
DE69124365D1
DE69124365D1 DE69124365T DE69124365T DE69124365D1 DE 69124365 D1 DE69124365 D1 DE 69124365D1 DE 69124365 T DE69124365 T DE 69124365T DE 69124365 T DE69124365 T DE 69124365T DE 69124365 D1 DE69124365 D1 DE 69124365D1
Authority
DE
Germany
Prior art keywords
skin
ultra
materials
increased administration
sound increased
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69124365T
Other languages
English (en)
Other versions
DE69124365T2 (de
Inventor
Durairaj Bommannan
Hirohisa Okuyama
Richard Guy
Paul Stauffer
Gordon Flynn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Animas Technologies LLC
Original Assignee
University of California
Cygnus Therapeutic Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California, Cygnus Therapeutic Systems filed Critical University of California
Application granted granted Critical
Publication of DE69124365D1 publication Critical patent/DE69124365D1/de
Publication of DE69124365T2 publication Critical patent/DE69124365T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N7/02—Localised ultrasound hyperthermia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00747—Dermatology
    • A61B2017/00765—Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
DE69124365T 1990-02-23 1991-02-21 Mittels ultraschall gesteigerte verabreichung von materialien durch die haut Expired - Fee Related DE69124365T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/484,560 US5115805A (en) 1990-02-23 1990-02-23 Ultrasound-enhanced delivery of materials into and through the skin
PCT/US1991/001207 WO1991012772A1 (en) 1990-02-23 1991-02-21 Ultrasound enhanced delivery of materials through skin

Publications (2)

Publication Number Publication Date
DE69124365D1 true DE69124365D1 (de) 1997-03-06
DE69124365T2 DE69124365T2 (de) 1997-05-28

Family

ID=23924657

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69124365T Expired - Fee Related DE69124365T2 (de) 1990-02-23 1991-02-21 Mittels ultraschall gesteigerte verabreichung von materialien durch die haut
DE69132175T Expired - Fee Related DE69132175T2 (de) 1990-02-23 1991-02-21 Nicht-invasives Verfahren zum Erhalt von Materialien durch die Haut

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69132175T Expired - Fee Related DE69132175T2 (de) 1990-02-23 1991-02-21 Nicht-invasives Verfahren zum Erhalt von Materialien durch die Haut

Country Status (15)

Country Link
US (3) US5115805A (de)
EP (2) EP0736305B1 (de)
JP (1) JP2695986B2 (de)
AT (2) ATE148001T1 (de)
AU (1) AU656519B2 (de)
CA (1) CA2075624C (de)
DE (2) DE69124365T2 (de)
DK (1) DK0736305T3 (de)
ES (2) ES2097206T3 (de)
FI (1) FI923743A0 (de)
GR (1) GR3034087T3 (de)
IE (1) IE910613A1 (de)
NZ (1) NZ237197A (de)
PT (1) PT96856A (de)
WO (1) WO1991012772A1 (de)

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CA2075624C (en) 1997-11-18
EP0515566A4 (en) 1993-02-03
JP2695986B2 (ja) 1998-01-14
US5636632A (en) 1997-06-10
US5323769A (en) 1994-06-28
DE69132175D1 (de) 2000-06-08
FI923743A (fi) 1992-08-20
EP0736305B1 (de) 2000-05-03
JPH06501855A (ja) 1994-03-03
DE69132175T2 (de) 2000-09-28
DK0736305T3 (da) 2000-12-04
IE910613A1 (en) 1991-08-28
ATE148001T1 (de) 1997-02-15
DE69124365T2 (de) 1997-05-28
EP0515566A1 (de) 1992-12-02
EP0515566B1 (de) 1997-01-22
EP0736305A3 (de) 1998-08-19
US5115805A (en) 1992-05-26
NZ237197A (en) 1997-04-24
GR3034087T3 (en) 2000-11-30
ES2097206T3 (es) 1997-04-01
CA2075624A1 (en) 1991-08-24
FI923743A0 (fi) 1992-08-20
ATE192344T1 (de) 2000-05-15
WO1991012772A1 (en) 1991-09-05
ES2146339T3 (es) 2000-08-01
EP0736305A2 (de) 1996-10-09
PT96856A (pt) 1991-11-29
AU7488391A (en) 1991-09-18

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