DE69130277T2 - Verfahren zur trennung optischer isomere - Google Patents
Verfahren zur trennung optischer isomereInfo
- Publication number
- DE69130277T2 DE69130277T2 DE69130277T DE69130277T DE69130277T2 DE 69130277 T2 DE69130277 T2 DE 69130277T2 DE 69130277 T DE69130277 T DE 69130277T DE 69130277 T DE69130277 T DE 69130277T DE 69130277 T2 DE69130277 T2 DE 69130277T2
- Authority
- DE
- Germany
- Prior art keywords
- optical isomers
- separating optical
- separating
- isomers
- optical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1814—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns recycling of the fraction to be distributed
- B01D15/1821—Simulated moving beds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3833—Chiral chromatography
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4413990 | 1990-02-23 | ||
JP3005669A JP2925753B2 (ja) | 1990-02-23 | 1991-01-22 | 光学異性体の分離方法 |
PCT/JP1991/000213 WO1991013046A1 (en) | 1990-02-23 | 1991-02-20 | Process for separating optical isomers |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69130277D1 DE69130277D1 (de) | 1998-11-05 |
DE69130277T2 true DE69130277T2 (de) | 1999-02-18 |
Family
ID=26339644
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69130277T Expired - Lifetime DE69130277T2 (de) | 1990-02-23 | 1991-02-20 | Verfahren zur trennung optischer isomere |
Country Status (5)
Country | Link |
---|---|
US (2) | USRE35919E (de) |
EP (1) | EP0471082B1 (de) |
JP (1) | JP2925753B2 (de) |
DE (1) | DE69130277T2 (de) |
WO (1) | WO1991013046A1 (de) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2962594B2 (ja) * | 1991-06-12 | 1999-10-12 | オルガノ株式会社 | 複数成分の分離方法 |
JP3010816B2 (ja) † | 1991-08-22 | 2000-02-21 | ダイセル化学工業株式会社 | 光学分割における光学異性体と溶媒との回収方法、溶媒の循環使用方法、および光学異性体の再利用方法 |
US5498752A (en) * | 1991-08-22 | 1996-03-12 | Daicel Chemical Industries, Ltd. | Process for recovering optical isomers and solvent, process for using solvent by circulation and process for reusing optical isomers in optical resolution |
JPH0779927B2 (ja) * | 1992-05-22 | 1995-08-30 | 川崎重工業株式会社 | 擬似移動床式液体クロマトオリゴ糖分離装置 |
EP0577079B1 (de) * | 1992-06-30 | 1999-12-01 | Daicel Chemical Industries, Ltd. | Trennsystem mit simuliertem Fliessbett |
US5770088A (en) * | 1992-06-30 | 1998-06-23 | Daicel Chemical Industries, Ltd. | Simulated moving bed chromatographic separation process |
JP3070890B2 (ja) * | 1993-02-12 | 2000-07-31 | オルガノ株式会社 | 澱粉糖の製造方法 |
EP0747341B1 (de) * | 1994-02-25 | 2002-05-22 | Daicel Chemical Industries, Ltd. | Verfahren zur herstellung von optisch aktiven mevalonolactonen |
US5470464A (en) * | 1994-04-06 | 1995-11-28 | Uop | Small scale simulated moving bed separation apparatus and process |
JPH07285889A (ja) * | 1994-04-20 | 1995-10-31 | Daicel Chem Ind Ltd | 光学異性体の分離方法 |
US5405992A (en) * | 1994-04-28 | 1995-04-11 | Uop | Process for concurrent esterification and separation using a simulated moving bed |
EP0687491A1 (de) * | 1994-06-16 | 1995-12-20 | Daicel Chemical Industries, Ltd. | Chromatographisches simuliertes Wanderbetttrennungsverfahren |
CN1116088C (zh) * | 1994-06-17 | 2003-07-30 | 代科化学工业株式会社 | 模拟移动床色谱分离方法 |
JPH08176133A (ja) * | 1994-12-26 | 1996-07-09 | Takeda Chem Ind Ltd | L−アスコルビン酸の精製法 |
US5645729A (en) * | 1995-02-13 | 1997-07-08 | Uop | Separations by simulated moving bed chromatography operating at low k' values using weakly interacting adsorbents as the stationary phase |
US5518625A (en) * | 1995-02-13 | 1996-05-21 | Uop | Chiral separations by simulated moving bed chromatography operating at low k' values |
US5626762A (en) * | 1995-02-13 | 1997-05-06 | Uop | Separations by simulated moving bed chromatography operating at low K' values using weakly interating adsorbents as the stationary phase |
FR2754731B1 (fr) * | 1996-10-18 | 1999-07-02 | Novasep Sa | Perfectionnement aux procedes d'enrichissement d'isomeres optiques par lit mobile simule |
FR2754730B1 (fr) * | 1996-10-18 | 1999-07-02 | Novasep Sa | Procede d'enrichissement d'isomeres optiques par lit mobile simule |
US5928515A (en) * | 1997-12-12 | 1999-07-27 | Uop Llc | Adsorptive separation of 3-hydroxytetrahydrofuran enantiomers |
US6107492A (en) * | 1998-05-08 | 2000-08-22 | Ucb, S.A. | Process for the preparation of levetiracetam |
US6379552B1 (en) * | 1998-07-06 | 2002-04-30 | Toray Industries, Inc. | Method for resolving optical isomers |
EP2682397B1 (de) | 2000-07-21 | 2017-04-19 | Gilead Sciences, Inc. | Prodrugs von Phosphonatnucleotidanaloga und Verfahren zur Auswahl und Herstellung davon |
EP1331214A4 (de) * | 2000-10-13 | 2006-08-02 | Daicel Chem | Packungsmaterial zur trennung optischer isomere und verfahren zur trennung optischer isomere unter anwendung dieses materials |
US6977301B1 (en) | 2001-05-29 | 2005-12-20 | Ucb, S.A. | Process for preparing (S) and (R)—2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide |
US7199241B1 (en) | 2001-05-29 | 2007-04-03 | Ucb, S.A. | Process for preparing (S) and (R)-2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide |
JP2004003935A (ja) * | 2002-04-12 | 2004-01-08 | Daicel Chem Ind Ltd | 擬似移動床式クロマトグラフィー用光学異性体分離用充填剤 |
KR20040028303A (ko) * | 2002-09-30 | 2004-04-03 | 다이셀 가가꾸 고교 가부시끼가이샤 | 의사(擬似)이동마루식 크로마토그래피에 의한 광학 분할에있어서의 광학 이성체와 용매와의 회수 방법 및 용매의순환 사용 방법 |
DE102004025000A1 (de) | 2004-05-21 | 2005-12-08 | Bayer Technology Services Gmbh | Verfahren zur Herstellung von chemischen und pharmazeutischen Produkten mit integrierter Mehrsäulen-Chromatographie |
JP4771460B2 (ja) * | 2005-08-18 | 2011-09-14 | オルガノ株式会社 | クロマト分離方法 |
CN104387237B (zh) * | 2014-01-22 | 2016-01-27 | 江苏汉邦科技有限公司 | 模拟移动床色谱拆分4-氯二苯甲醇对映体的方法 |
CN107952483B (zh) * | 2017-12-18 | 2020-07-28 | 万华化学集团股份有限公司 | 一种催化剂,使用该催化剂的反应器,以及一种制备β-苯乙醇的方法 |
CN110465114B (zh) * | 2019-08-23 | 2021-08-20 | 内蒙古金达威药业有限公司 | 一种模拟移动床连续层析色谱系统及其应用以及纯化辅酶q10的方法 |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2985589A (en) * | 1957-05-22 | 1961-05-23 | Universal Oil Prod Co | Continuous sorption process employing fixed bed of sorbent and moving inlets and outlets |
US4042327A (en) * | 1976-01-15 | 1977-08-16 | Waters Associates, Inc. | Ion-pairing chromatography |
DE2709094C2 (de) * | 1977-03-02 | 1984-11-22 | Boehringer Mannheim Gmbh, 6800 Mannheim | Adsorbens für die affinitätsspezifische Trennung von Nukleinsäuren, Verfahren zu seiner Herstellung und seine Verwendung |
US4416784A (en) * | 1980-01-28 | 1983-11-22 | Kureha Kagaku Kogyo Kabushiki Kaisha | Filling composition for use in liquid chromatography |
US4549965A (en) * | 1980-09-02 | 1985-10-29 | The Dow Chemical Company | Liquid chromatographic method and apparatus with membrane for post-column derivatization |
JPS5820208A (ja) * | 1981-07-31 | 1983-02-05 | Asahi Chem Ind Co Ltd | 吸着分離方法 |
US4381399A (en) * | 1981-12-21 | 1983-04-26 | Aerojet-General Corporation | Purification of tetrahydrodibenzo[b,d]pyrans from crude synthetic mixtures |
US4402832A (en) * | 1982-08-12 | 1983-09-06 | Uop Inc. | High efficiency continuous separation process |
CA1204720A (en) * | 1982-09-30 | 1986-05-20 | Hajimu Kitahara | Packing materials for chromatographic use and a method for analysis of an enantiomer mixture using the same |
JPS60142930A (ja) * | 1983-12-28 | 1985-07-29 | Daicel Chem Ind Ltd | 分離剤 |
JPS60226833A (ja) * | 1984-04-05 | 1985-11-12 | Daicel Chem Ind Ltd | 多糖の芳香族エステル誘導体より成る分離剤 |
US4816445A (en) * | 1984-06-21 | 1989-03-28 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Crystalline alpha-maltose |
US4539399A (en) * | 1984-07-27 | 1985-09-03 | Advanced Separation Technologies Inc. | Bonded phase material for chromatographic separations |
GB2167052B (en) * | 1984-11-17 | 1988-09-07 | Laporte Industries Ltd | Synthetic crystalline molecular sieve materials and a method for their preparation |
SE452762B (sv) * | 1985-06-28 | 1987-12-14 | Borje Sellergren | Anvendning av ett vattenhaltigt tvafassystem for kiral upplosning av racemiska blandningar eller for separation av diastereomerer samt ett sadant forfarande |
FR2593409B1 (fr) * | 1986-01-30 | 1990-08-24 | Centre Nat Rech Scient | Procede de separation des constituants d'un melange comprenant au moins deux composes connus pour etre difficiles a separer et faisant appel au phenomene d'adsorption |
JPS62210053A (ja) * | 1986-03-07 | 1987-09-16 | Agency Of Ind Science & Technol | 光学異性体分離用充填剤 |
JPS6327502A (ja) * | 1986-07-22 | 1988-02-05 | Agency Of Ind Science & Technol | シクロデキストリン−シリカ複合体及びその製造方法 |
JP2635349B2 (ja) * | 1988-02-08 | 1997-07-30 | 株式会社資生堂 | 液体クロマトグラフィー用充填剤 |
JPS6485106A (en) * | 1987-09-24 | 1989-03-30 | Mitsubishi Petrochemical Co | Separation in pseudo moving bed |
US4765903A (en) * | 1987-10-06 | 1988-08-23 | Interferon Sciences, Inc. | Purification of monomeric interferon |
JPH01163654A (ja) * | 1987-12-21 | 1989-06-27 | Daiso Co Ltd | 光学分割用充填剤 |
JPH01199643A (ja) * | 1988-01-30 | 1989-08-11 | Mitsubishi Kasei Corp | 光学分割用吸着剤 |
JPH01216943A (ja) * | 1988-02-26 | 1989-08-30 | Mitsui Toatsu Chem Inc | 光学分割用分離剤 |
US4919803A (en) * | 1988-12-09 | 1990-04-24 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Liquid chromatographic chiral stationary phase |
DE4010528A1 (de) * | 1990-04-02 | 1991-10-17 | Boehringer Ingelheim Kg | Praeparativ chromatographisches trennverfahren zur herstellung enantiomerenreiner hetrazepine |
-
1991
- 1991-01-22 JP JP3005669A patent/JP2925753B2/ja not_active Expired - Lifetime
- 1991-02-20 DE DE69130277T patent/DE69130277T2/de not_active Expired - Lifetime
- 1991-02-20 EP EP91904337A patent/EP0471082B1/de not_active Expired - Lifetime
- 1991-02-20 WO PCT/JP1991/000213 patent/WO1991013046A1/ja active IP Right Grant
- 1991-02-20 US US08/911,680 patent/USRE35919E/en not_active Expired - Lifetime
- 1991-02-20 US US07/752,663 patent/US5126055A/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
JP2925753B2 (ja) | 1999-07-28 |
US5126055A (en) | 1992-06-30 |
USRE35919E (en) | 1998-10-13 |
EP0471082A4 (en) | 1993-07-28 |
EP0471082B1 (de) | 1998-09-30 |
WO1991013046A1 (en) | 1991-09-05 |
JPH04211021A (ja) | 1992-08-03 |
EP0471082A1 (de) | 1992-02-19 |
DE69130277D1 (de) | 1998-11-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent |