DE69200445D1 - Verfahren zur lumineszenzmessung in einer lumineszenzbestimmung. - Google Patents
Verfahren zur lumineszenzmessung in einer lumineszenzbestimmung.Info
- Publication number
- DE69200445D1 DE69200445D1 DE69200445T DE69200445T DE69200445D1 DE 69200445 D1 DE69200445 D1 DE 69200445D1 DE 69200445 T DE69200445 T DE 69200445T DE 69200445 T DE69200445 T DE 69200445T DE 69200445 D1 DE69200445 D1 DE 69200445D1
- Authority
- DE
- Germany
- Prior art keywords
- luminescence
- pct
- measurement
- lambda
- luminescent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6417—Spectrofluorimetric devices
- G01N2021/6421—Measuring at two or more wavelengths
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
- G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
- G01N21/274—Calibration, base line adjustment, drift correction
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/973—Simultaneous determination of more than one analyte
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/825—Pretreatment for removal of interfering factors from sample
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/13—Tracers or tags
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9100930A FR2672128B1 (fr) | 1991-01-28 | 1991-01-28 | Procede de mesure de la luminescence emise dans un dosage par luminescence. |
PCT/FR1992/000069 WO1992013264A1 (fr) | 1991-01-28 | 1992-01-27 | Procede de mesure de la luminescence emise dans un dosage par luminescence |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69200445D1 true DE69200445D1 (de) | 1994-10-27 |
DE69200445T2 DE69200445T2 (de) | 1995-02-16 |
Family
ID=9409109
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69200445T Expired - Lifetime DE69200445T2 (de) | 1991-01-28 | 1992-01-27 | Verfahren zur lumineszenzmessung in einer lumineszenzbestimmung. |
Country Status (10)
Country | Link |
---|---|
US (1) | US5527684A (de) |
EP (1) | EP0569496B1 (de) |
JP (1) | JP3233285B2 (de) |
AT (1) | ATE112055T1 (de) |
AU (1) | AU1274292A (de) |
DE (1) | DE69200445T2 (de) |
DK (1) | DK0569496T3 (de) |
ES (1) | ES2066602T3 (de) |
FR (1) | FR2672128B1 (de) |
WO (1) | WO1992013264A1 (de) |
Families Citing this family (63)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6352672B1 (en) | 1991-01-28 | 2002-03-05 | Cis Bio International | Apparatus for measuring the luminescence emitted in a luminescent assay |
US6861264B2 (en) * | 1992-01-27 | 2005-03-01 | Cis Bio International | Method of measuring the luminescence emitted in a luminescent assay |
ES2176229T3 (es) * | 1993-03-19 | 2002-12-01 | Novartis Ag | Compuestos quimioluminiscentes de longitud de onda de emision larga y su uso en ensayos de prueba. |
US5395752A (en) * | 1993-03-19 | 1995-03-07 | Ciba Corning Diagnostics Corp. | Long emission wavelength chemiluminescent compounds and their use in test assays |
EP0711992B1 (de) * | 1994-11-08 | 2003-03-26 | Tosoh Corporation | Verfahren zur Bestimmung einer fluoreszierenden Substanz, sowie Verfahren zur Enzym-Aktivität-Bestimmung |
CA2164167A1 (en) * | 1994-12-20 | 1996-06-21 | Izak Bahar | Assay normalization method |
US5736333A (en) * | 1996-06-04 | 1998-04-07 | The Perkin-Elmer Corporation | Passive internal references for the detection of nucleic acid amplification products |
JP3716502B2 (ja) * | 1996-07-24 | 2005-11-16 | 東ソー株式会社 | 蛍光検出装置 |
US5985214A (en) | 1997-05-16 | 1999-11-16 | Aurora Biosciences Corporation | Systems and methods for rapidly identifying useful chemicals in liquid samples |
US6258326B1 (en) | 1997-09-20 | 2001-07-10 | Ljl Biosystems, Inc. | Sample holders with reference fiducials |
US6469311B1 (en) | 1997-07-16 | 2002-10-22 | Molecular Devices Corporation | Detection device for light transmitted from a sensed volume |
US6071748A (en) | 1997-07-16 | 2000-06-06 | Ljl Biosystems, Inc. | Light detection device |
US6121050A (en) * | 1997-08-29 | 2000-09-19 | Han; Chi-Neng Arthur | Analyte detection systems |
US7745142B2 (en) | 1997-09-15 | 2010-06-29 | Molecular Devices Corporation | Molecular modification assays |
US6992761B2 (en) * | 1997-09-20 | 2006-01-31 | Molecular Devices Corporation | Broad range light detection system |
US6825921B1 (en) | 1999-11-10 | 2004-11-30 | Molecular Devices Corporation | Multi-mode light detection system |
US6576476B1 (en) | 1998-09-02 | 2003-06-10 | Ljl Biosystems, Inc. | Chemiluminescence detection method and device |
WO2000050877A1 (en) | 1999-02-23 | 2000-08-31 | Ljl Biosystems, Inc. | Frequency-domain light detection device |
WO2000006990A2 (en) | 1998-07-27 | 2000-02-10 | Ljl Biosystems, Inc. | Apparatus and methods for time-resolved spectroscopic measurements |
US6297018B1 (en) | 1998-04-17 | 2001-10-02 | Ljl Biosystems, Inc. | Methods and apparatus for detecting nucleic acid polymorphisms |
US6326605B1 (en) | 1998-02-20 | 2001-12-04 | Ljl Biosystems, Inc. | Broad range light detection system |
FR2769315B1 (fr) * | 1997-10-03 | 2001-06-08 | Cis Bio Int | Conjugues fluorescents de nucleosides ou de nucleotides, leur procede de preparation et leur utilisation |
US6653088B1 (en) * | 1997-10-24 | 2003-11-25 | Aventis Pharma S.A. | Interaction test for the investigation of inhibitory molecules of the interaction between a presenilin and the β-amyloid peptide |
DE19756773A1 (de) | 1997-12-19 | 1999-06-24 | Dade Behring Marburg Gmbh | Neues Verfahren und Diagnosemittel zur Hämostase-Diagnostik |
DE19756782A1 (de) | 1997-12-19 | 1999-06-24 | Dade Behring Marburg Gmbh | Nachweis und Bestimmung festphasenassoziierter Faktoren |
EP3093649B1 (de) * | 1998-05-16 | 2019-05-08 | Life Technologies Corporation | Eine kombination einer reaktionsvorrichtung und eines optischen instruments zur überwachung von dns-polymerasekettenreaktionen |
US6818437B1 (en) | 1998-05-16 | 2004-11-16 | Applera Corporation | Instrument for monitoring polymerase chain reaction of DNA |
US7498164B2 (en) | 1998-05-16 | 2009-03-03 | Applied Biosystems, Llc | Instrument for monitoring nucleic acid sequence amplification reaction |
AU5223899A (en) | 1998-07-27 | 2000-02-21 | Ljl Biosystems, Inc. | Apparatus and methods for spectroscopic measurements |
WO2000014515A1 (en) * | 1998-09-08 | 2000-03-16 | University Of Maryland At Baltimore | Low frequency modulation sensors using nanosecond fluorophores |
US6806089B1 (en) | 1998-09-08 | 2004-10-19 | University Of Maryland, Baltimore | Low frequency modulation sensors using nanosecond fluorophores |
US6410255B1 (en) * | 1999-05-05 | 2002-06-25 | Aurora Biosciences Corporation | Optical probes and assays |
US6569685B1 (en) * | 1999-10-05 | 2003-05-27 | The Molecular Sciences Institute, Inc. | Protein fingerprint system and related methods |
WO2001067105A1 (en) | 2000-03-06 | 2001-09-13 | Dade Behring Marburg Gmbh | Carriers coated with polysaccharides, their preparation and use |
AU2002249778A1 (en) * | 2000-11-17 | 2002-08-12 | Thermogenic Imaging, Inc. | Apparatus and methods for infrared calorimetric measurements |
US20020132360A1 (en) * | 2000-11-17 | 2002-09-19 | Flir Systems Boston, Inc. | Apparatus and methods for infrared calorimetric measurements |
US7727752B2 (en) | 2003-07-29 | 2010-06-01 | Life Technologies Corporation | Kinase and phosphatase assays |
CA2445420A1 (en) | 2003-07-29 | 2005-01-29 | Invitrogen Corporation | Kinase and phosphatase assays |
US7619059B2 (en) | 2003-07-29 | 2009-11-17 | Life Technologies Corporation | Bimolecular optical probes |
JP2007505315A (ja) * | 2003-09-12 | 2007-03-08 | インヴィトロジェン コーポレーション | 多重結合および活性アッセイ |
CA2547351A1 (en) * | 2003-12-01 | 2005-07-07 | Dade Behring Marburg Gmbh | Homogeneous detection method |
US20050118727A1 (en) * | 2003-12-01 | 2005-06-02 | Carsten Schelp | Conjugates and their use in detection methods |
WO2006039505A2 (en) | 2004-09-30 | 2006-04-13 | Molecular Devices Corporation | Luminescent lanthanide complexes |
FR2878850B1 (fr) * | 2004-12-02 | 2008-10-31 | Cis Bio Internat Sa | Derives de l'inositol-1-phosphate |
FR2890446B1 (fr) | 2005-09-05 | 2008-04-18 | Cis Bio Internat Sa | Methode de detection d'interaction intracellulaire entre bio-molecules |
US7772009B2 (en) * | 2005-11-22 | 2010-08-10 | SCR Research, LLC | Room temperature phosphorescence apparatus and methods |
BRPI0717416A2 (pt) | 2006-09-21 | 2013-11-12 | Prometheus Lab Inc | Método para realizar um imunoensaio complexo de alta produtividade, e, arranjo |
EP2179291B1 (de) * | 2007-07-13 | 2014-10-22 | Nestec S.A. | Arzneistoffauswahl für die lungenkrebstherapie unter verwendung von arrays auf antikörperbasis |
ES2398618T3 (es) | 2008-02-25 | 2013-03-20 | Nestec S.A. | Selección de fármacos para terapia del cáncer de mama utilizando matrices de anticuerpos |
EP2288918A1 (de) * | 2008-05-23 | 2011-03-02 | Amylin Pharmaceuticals, Inc. | Glp-1-rezeptor-agonist-bioassays |
JP5795311B2 (ja) | 2009-07-15 | 2015-10-14 | ネステク ソシエテ アノニム | 抗体ベースのアレイを使用する胃癌療法のための薬物選択 |
US8778614B2 (en) | 2010-08-24 | 2014-07-15 | Enzo Life Sciences, Inc. | Assays for detecting modified compounds |
EP2616817A4 (de) | 2010-09-15 | 2014-04-09 | Endacea Inc | Verfahren zur verwendung und kit zur messung von lipopolysacchariden mit einem zeitgesteuerten assay auf fluoreszenzbasis |
EP3028720A1 (de) | 2010-09-28 | 2016-06-08 | Amylin Pharmaceuticals, LLC | Manipulierte polypeptide mit verlängerter wirkungsdauer |
US9719995B2 (en) | 2011-02-03 | 2017-08-01 | Pierian Holdings, Inc. | Drug selection for colorectal cancer therapy using receptor tyrosine kinase profiling |
US9382304B2 (en) | 2011-07-08 | 2016-07-05 | Amylin Pharmaceuticals, Llc | Engineered polypeptides having enhanced duration of action with reduced immunogenicity |
EP2751562B1 (de) | 2011-09-02 | 2015-09-16 | Nestec S.A. | Profilierung von signalwegproteinen zur bestimmung der therapeutischen wirksamkeit |
US20150185150A1 (en) * | 2012-02-22 | 2015-07-02 | Cisbio Bioassays | Method for normalizing the luminescence emitted by a measuring medium |
CA3010895A1 (en) | 2016-01-21 | 2017-07-27 | SeLux Diagnostics, Inc. | Methods for rapid antimicrobial susceptibility testing |
US9834808B2 (en) | 2016-01-21 | 2017-12-05 | SeLux Diagnostics, Inc. | Methods for rapid antibiotic susceptibility testing |
CA3048213A1 (en) | 2016-12-23 | 2018-06-28 | Eric Stern | Methods for improved rapid antimicrobial susceptibility testing |
CA3152541A1 (en) | 2019-08-27 | 2021-03-04 | SeLux Diagnostics, Inc. | Systems and methods for performing antimicrobial susceptibility testing |
EP4299125A1 (de) | 2022-06-30 | 2024-01-03 | Universite De Montpellier | Anti-mglur2-biparatopische nanokörper und deren verwendungen |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4341957A (en) * | 1975-11-26 | 1982-07-27 | Analytical Radiation Corporation | Fluorescent antibody composition for immunofluorometric assay |
US4100416A (en) * | 1977-03-02 | 1978-07-11 | Block Engineering, Inc. | Serum fluorescence suppression |
US4542104A (en) * | 1983-04-06 | 1985-09-17 | The Board Of Trustees Of The Leland Stanford Jr. Univ. | Phycobiliprotein fluorescent conjugates |
US4868103A (en) * | 1986-02-19 | 1989-09-19 | Enzo Biochem, Inc. | Analyte detection by means of energy transfer |
EP0266881A3 (de) * | 1986-09-30 | 1990-04-04 | Astromed Limited | Verfahren und Vorrichtung für optische Mehrfachprüfung |
US4954435A (en) * | 1987-01-12 | 1990-09-04 | Becton, Dickinson And Company | Indirect colorimetric detection of an analyte in a sample using ratio of light signals |
US4876190A (en) * | 1987-10-21 | 1989-10-24 | Becton Dickinson & Company | Peridinin-chlorophyll complex as fluorescent label |
GB2215838B (en) * | 1988-02-12 | 1992-10-21 | Nat Res Dev | Fluorimeters |
GB2228081B (en) * | 1988-12-06 | 1993-07-07 | Loughborough Consult Ltd | A fluorimeter, and a method of carrying out a fluorescent assay of a plurality of analytes |
-
1991
- 1991-01-28 FR FR9100930A patent/FR2672128B1/fr not_active Expired - Fee Related
-
1992
- 1992-01-27 WO PCT/FR1992/000069 patent/WO1992013264A1/fr active IP Right Grant
- 1992-01-27 US US08/094,085 patent/US5527684A/en not_active Expired - Lifetime
- 1992-01-27 ES ES92905184T patent/ES2066602T3/es not_active Expired - Lifetime
- 1992-01-27 AU AU12742/92A patent/AU1274292A/en not_active Abandoned
- 1992-01-27 JP JP50501492A patent/JP3233285B2/ja not_active Expired - Lifetime
- 1992-01-27 AT AT92905184T patent/ATE112055T1/de not_active IP Right Cessation
- 1992-01-27 EP EP92905184A patent/EP0569496B1/de not_active Expired - Lifetime
- 1992-01-27 DE DE69200445T patent/DE69200445T2/de not_active Expired - Lifetime
- 1992-01-27 DK DK92905184.5T patent/DK0569496T3/da active
Also Published As
Publication number | Publication date |
---|---|
AU1274292A (en) | 1992-08-27 |
ATE112055T1 (de) | 1994-10-15 |
FR2672128A1 (fr) | 1992-07-31 |
WO1992013264A1 (fr) | 1992-08-06 |
JPH06508919A (ja) | 1994-10-06 |
EP0569496A1 (de) | 1993-11-18 |
DK0569496T3 (da) | 1995-03-06 |
ES2066602T3 (es) | 1995-03-01 |
FR2672128B1 (fr) | 1995-08-18 |
US5527684A (en) | 1996-06-18 |
DE69200445T2 (de) | 1995-02-16 |
EP0569496B1 (de) | 1994-09-21 |
JP3233285B2 (ja) | 2001-11-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |