DE69200445T2 - Verfahren zur lumineszenzmessung in einer lumineszenzbestimmung. - Google Patents
Verfahren zur lumineszenzmessung in einer lumineszenzbestimmung.Info
- Publication number
- DE69200445T2 DE69200445T2 DE69200445T DE69200445T DE69200445T2 DE 69200445 T2 DE69200445 T2 DE 69200445T2 DE 69200445 T DE69200445 T DE 69200445T DE 69200445 T DE69200445 T DE 69200445T DE 69200445 T2 DE69200445 T2 DE 69200445T2
- Authority
- DE
- Germany
- Prior art keywords
- luminescence
- pct
- measurement
- lambda
- luminescent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6417—Spectrofluorimetric devices
- G01N2021/6421—Measuring at two or more wavelengths
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
- G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
- G01N21/274—Calibration, base line adjustment, drift correction
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/973—Simultaneous determination of more than one analyte
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/825—Pretreatment for removal of interfering factors from sample
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/13—Tracers or tags
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9100930A FR2672128B1 (fr) | 1991-01-28 | 1991-01-28 | Procede de mesure de la luminescence emise dans un dosage par luminescence. |
PCT/FR1992/000069 WO1992013264A1 (fr) | 1991-01-28 | 1992-01-27 | Procede de mesure de la luminescence emise dans un dosage par luminescence |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69200445D1 DE69200445D1 (de) | 1994-10-27 |
DE69200445T2 true DE69200445T2 (de) | 1995-02-16 |
Family
ID=9409109
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69200445T Expired - Lifetime DE69200445T2 (de) | 1991-01-28 | 1992-01-27 | Verfahren zur lumineszenzmessung in einer lumineszenzbestimmung. |
Country Status (10)
Country | Link |
---|---|
US (1) | US5527684A (de) |
EP (1) | EP0569496B1 (de) |
JP (1) | JP3233285B2 (de) |
AT (1) | ATE112055T1 (de) |
AU (1) | AU1274292A (de) |
DE (1) | DE69200445T2 (de) |
DK (1) | DK0569496T3 (de) |
ES (1) | ES2066602T3 (de) |
FR (1) | FR2672128B1 (de) |
WO (1) | WO1992013264A1 (de) |
Families Citing this family (63)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6352672B1 (en) | 1991-01-28 | 2002-03-05 | Cis Bio International | Apparatus for measuring the luminescence emitted in a luminescent assay |
US6861264B2 (en) * | 1992-01-27 | 2005-03-01 | Cis Bio International | Method of measuring the luminescence emitted in a luminescent assay |
US5395752A (en) * | 1993-03-19 | 1995-03-07 | Ciba Corning Diagnostics Corp. | Long emission wavelength chemiluminescent compounds and their use in test assays |
ATE217087T1 (de) * | 1993-03-19 | 2002-05-15 | Novartis Ag | Chemilumineszierende derivate mit langer emissionswellenlänge und ihre verwendung in assays |
DE69530043T2 (de) * | 1994-11-08 | 2003-10-16 | Tosoh Corp | Verfahren zur Bestimmung einer fluoreszierenden Substanz, sowie Verfahren zur Enzym-Aktivität-Bestimmung |
CA2164167A1 (en) * | 1994-12-20 | 1996-06-21 | Izak Bahar | Assay normalization method |
US5736333A (en) * | 1996-06-04 | 1998-04-07 | The Perkin-Elmer Corporation | Passive internal references for the detection of nucleic acid amplification products |
JP3716502B2 (ja) * | 1996-07-24 | 2005-11-16 | 東ソー株式会社 | 蛍光検出装置 |
US5985214A (en) * | 1997-05-16 | 1999-11-16 | Aurora Biosciences Corporation | Systems and methods for rapidly identifying useful chemicals in liquid samples |
US6258326B1 (en) | 1997-09-20 | 2001-07-10 | Ljl Biosystems, Inc. | Sample holders with reference fiducials |
US6071748A (en) | 1997-07-16 | 2000-06-06 | Ljl Biosystems, Inc. | Light detection device |
US6469311B1 (en) | 1997-07-16 | 2002-10-22 | Molecular Devices Corporation | Detection device for light transmitted from a sensed volume |
US6121050A (en) * | 1997-08-29 | 2000-09-19 | Han; Chi-Neng Arthur | Analyte detection systems |
US7745142B2 (en) | 1997-09-15 | 2010-06-29 | Molecular Devices Corporation | Molecular modification assays |
US6992761B2 (en) * | 1997-09-20 | 2006-01-31 | Molecular Devices Corporation | Broad range light detection system |
WO2000006990A2 (en) | 1998-07-27 | 2000-02-10 | Ljl Biosystems, Inc. | Apparatus and methods for time-resolved spectroscopic measurements |
US6326605B1 (en) | 1998-02-20 | 2001-12-04 | Ljl Biosystems, Inc. | Broad range light detection system |
US6297018B1 (en) | 1998-04-17 | 2001-10-02 | Ljl Biosystems, Inc. | Methods and apparatus for detecting nucleic acid polymorphisms |
US6825921B1 (en) | 1999-11-10 | 2004-11-30 | Molecular Devices Corporation | Multi-mode light detection system |
US6576476B1 (en) | 1998-09-02 | 2003-06-10 | Ljl Biosystems, Inc. | Chemiluminescence detection method and device |
WO2000006991A2 (en) | 1998-07-27 | 2000-02-10 | Ljl Biosystems, Inc. | Apparatus and methods for spectroscopic measurements |
FR2769315B1 (fr) * | 1997-10-03 | 2001-06-08 | Cis Bio Int | Conjugues fluorescents de nucleosides ou de nucleotides, leur procede de preparation et leur utilisation |
US6653088B1 (en) * | 1997-10-24 | 2003-11-25 | Aventis Pharma S.A. | Interaction test for the investigation of inhibitory molecules of the interaction between a presenilin and the β-amyloid peptide |
DE19756782A1 (de) | 1997-12-19 | 1999-06-24 | Dade Behring Marburg Gmbh | Nachweis und Bestimmung festphasenassoziierter Faktoren |
DE19756773A1 (de) | 1997-12-19 | 1999-06-24 | Dade Behring Marburg Gmbh | Neues Verfahren und Diagnosemittel zur Hämostase-Diagnostik |
US6818437B1 (en) * | 1998-05-16 | 2004-11-16 | Applera Corporation | Instrument for monitoring polymerase chain reaction of DNA |
US7498164B2 (en) | 1998-05-16 | 2009-03-03 | Applied Biosystems, Llc | Instrument for monitoring nucleic acid sequence amplification reaction |
WO1999060381A1 (en) * | 1998-05-16 | 1999-11-25 | The Perkin-Elmer Corporation | Instrument for monitoring polymerase chain reaction of dna |
WO2000014515A1 (en) * | 1998-09-08 | 2000-03-16 | University Of Maryland At Baltimore | Low frequency modulation sensors using nanosecond fluorophores |
US6806089B1 (en) | 1998-09-08 | 2004-10-19 | University Of Maryland, Baltimore | Low frequency modulation sensors using nanosecond fluorophores |
AU3005400A (en) | 1999-02-23 | 2000-09-14 | Ljl Biosystems, Inc. | Frequency-domain light detection device |
US6410255B1 (en) * | 1999-05-05 | 2002-06-25 | Aurora Biosciences Corporation | Optical probes and assays |
US6569685B1 (en) | 1999-10-05 | 2003-05-27 | The Molecular Sciences Institute, Inc. | Protein fingerprint system and related methods |
ES2287006T3 (es) | 2000-03-06 | 2007-12-16 | Dade Behring Marburg Gmbh | Vehiculos revestidos con polisacaridos, su preparacion y uso. |
US20020132360A1 (en) * | 2000-11-17 | 2002-09-19 | Flir Systems Boston, Inc. | Apparatus and methods for infrared calorimetric measurements |
AU2002249778A1 (en) * | 2000-11-17 | 2002-08-12 | Thermogenic Imaging, Inc. | Apparatus and methods for infrared calorimetric measurements |
CA2445420A1 (en) | 2003-07-29 | 2005-01-29 | Invitrogen Corporation | Kinase and phosphatase assays |
US7619059B2 (en) | 2003-07-29 | 2009-11-17 | Life Technologies Corporation | Bimolecular optical probes |
US7727752B2 (en) | 2003-07-29 | 2010-06-01 | Life Technologies Corporation | Kinase and phosphatase assays |
JP2007505315A (ja) * | 2003-09-12 | 2007-03-08 | インヴィトロジェン コーポレーション | 多重結合および活性アッセイ |
JP2007512543A (ja) * | 2003-12-01 | 2007-05-17 | デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング | ホモジニアスな検出方法 |
US20050118727A1 (en) * | 2003-12-01 | 2005-06-02 | Carsten Schelp | Conjugates and their use in detection methods |
WO2006039505A2 (en) | 2004-09-30 | 2006-04-13 | Molecular Devices Corporation | Luminescent lanthanide complexes |
FR2878850B1 (fr) | 2004-12-02 | 2008-10-31 | Cis Bio Internat Sa | Derives de l'inositol-1-phosphate |
FR2890446B1 (fr) | 2005-09-05 | 2008-04-18 | Cis Bio Internat Sa | Methode de detection d'interaction intracellulaire entre bio-molecules |
US7772009B2 (en) * | 2005-11-22 | 2010-08-10 | SCR Research, LLC | Room temperature phosphorescence apparatus and methods |
BRPI0717416A2 (pt) | 2006-09-21 | 2013-11-12 | Prometheus Lab Inc | Método para realizar um imunoensaio complexo de alta produtividade, e, arranjo |
WO2011008990A1 (en) | 2009-07-15 | 2011-01-20 | Prometheus Laboratories Inc. | Drug selection for gastric cancer therapy using antibody-based arrays |
AU2008276251B2 (en) * | 2007-07-13 | 2014-04-24 | Nestec S.A. | Drug selection for lung cancer therapy using antibody-based arrays |
DK2602623T3 (en) | 2008-02-25 | 2015-11-09 | Nestec Sa | METHOD OF DETECTING INTRACELLULAR TRUNCTED RECEPTORS |
EP2288918A1 (de) * | 2008-05-23 | 2011-03-02 | Amylin Pharmaceuticals, Inc. | Glp-1-rezeptor-agonist-bioassays |
US8778614B2 (en) | 2010-08-24 | 2014-07-15 | Enzo Life Sciences, Inc. | Assays for detecting modified compounds |
US20130183696A1 (en) | 2010-09-15 | 2013-07-18 | Constance Neely Wilson | Methods of use and kit for measurement of lipopolysaccharide with a time resolved fluorescence based assay |
JP6121330B2 (ja) | 2010-09-28 | 2017-04-26 | アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc | 作用持続時間が増した改変ポリペプチド |
US9719995B2 (en) | 2011-02-03 | 2017-08-01 | Pierian Holdings, Inc. | Drug selection for colorectal cancer therapy using receptor tyrosine kinase profiling |
CN104271588B (zh) | 2011-07-08 | 2017-10-10 | 安米林药品有限责任公司 | 具有增强的作用持续时间和降低的免疫原性的工程改造的多肽 |
EP2751562B1 (de) | 2011-09-02 | 2015-09-16 | Nestec S.A. | Profilierung von signalwegproteinen zur bestimmung der therapeutischen wirksamkeit |
EP2817614A1 (de) * | 2012-02-22 | 2014-12-31 | Cisbio Bioassays | Verfahren zur normalisierung der von einem messmedium emittierten lumineszenz |
US9834808B2 (en) | 2016-01-21 | 2017-12-05 | SeLux Diagnostics, Inc. | Methods for rapid antibiotic susceptibility testing |
WO2017127684A1 (en) | 2016-01-21 | 2017-07-27 | SeLux Diagnostics, Inc. | Methods for rapid antimicrobial susceptibility testing |
BR112019012979A2 (pt) | 2016-12-23 | 2019-12-31 | Selux Diagnostics Inc | métodos para o teste de suscetibilidade antimicrobiana rápida melhorada |
AU2020340381A1 (en) | 2019-08-27 | 2022-04-07 | SeLux Diagnostics, Inc. | Systems and methods for performing antimicrobial susceptibility testing |
EP4299125A1 (de) | 2022-06-30 | 2024-01-03 | Universite De Montpellier | Anti-mglur2-biparatopische nanokörper und deren verwendungen |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4341957A (en) * | 1975-11-26 | 1982-07-27 | Analytical Radiation Corporation | Fluorescent antibody composition for immunofluorometric assay |
US4100416A (en) * | 1977-03-02 | 1978-07-11 | Block Engineering, Inc. | Serum fluorescence suppression |
US4542104A (en) * | 1983-04-06 | 1985-09-17 | The Board Of Trustees Of The Leland Stanford Jr. Univ. | Phycobiliprotein fluorescent conjugates |
US4868103A (en) * | 1986-02-19 | 1989-09-19 | Enzo Biochem, Inc. | Analyte detection by means of energy transfer |
EP0266881A3 (de) * | 1986-09-30 | 1990-04-04 | Astromed Limited | Verfahren und Vorrichtung für optische Mehrfachprüfung |
US4954435A (en) * | 1987-01-12 | 1990-09-04 | Becton, Dickinson And Company | Indirect colorimetric detection of an analyte in a sample using ratio of light signals |
US4876190A (en) * | 1987-10-21 | 1989-10-24 | Becton Dickinson & Company | Peridinin-chlorophyll complex as fluorescent label |
GB2215838B (en) * | 1988-02-12 | 1992-10-21 | Nat Res Dev | Fluorimeters |
GB2228081B (en) * | 1988-12-06 | 1993-07-07 | Loughborough Consult Ltd | A fluorimeter, and a method of carrying out a fluorescent assay of a plurality of analytes |
-
1991
- 1991-01-28 FR FR9100930A patent/FR2672128B1/fr not_active Expired - Fee Related
-
1992
- 1992-01-27 AT AT92905184T patent/ATE112055T1/de not_active IP Right Cessation
- 1992-01-27 DK DK92905184.5T patent/DK0569496T3/da active
- 1992-01-27 WO PCT/FR1992/000069 patent/WO1992013264A1/fr active IP Right Grant
- 1992-01-27 DE DE69200445T patent/DE69200445T2/de not_active Expired - Lifetime
- 1992-01-27 ES ES92905184T patent/ES2066602T3/es not_active Expired - Lifetime
- 1992-01-27 AU AU12742/92A patent/AU1274292A/en not_active Abandoned
- 1992-01-27 JP JP50501492A patent/JP3233285B2/ja not_active Expired - Lifetime
- 1992-01-27 US US08/094,085 patent/US5527684A/en not_active Expired - Lifetime
- 1992-01-27 EP EP92905184A patent/EP0569496B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DK0569496T3 (da) | 1995-03-06 |
DE69200445D1 (de) | 1994-10-27 |
JPH06508919A (ja) | 1994-10-06 |
ATE112055T1 (de) | 1994-10-15 |
EP0569496A1 (de) | 1993-11-18 |
AU1274292A (en) | 1992-08-27 |
WO1992013264A1 (fr) | 1992-08-06 |
EP0569496B1 (de) | 1994-09-21 |
JP3233285B2 (ja) | 2001-11-26 |
FR2672128B1 (fr) | 1995-08-18 |
ES2066602T3 (es) | 1995-03-01 |
FR2672128A1 (fr) | 1992-07-31 |
US5527684A (en) | 1996-06-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |