DE69232615T2 - Zusammensetzungen zur verhütung und/oder behandlung von pathologischen prozessen - Google Patents
Zusammensetzungen zur verhütung und/oder behandlung von pathologischen prozessenInfo
- Publication number
- DE69232615T2 DE69232615T2 DE69232615T DE69232615T DE69232615T2 DE 69232615 T2 DE69232615 T2 DE 69232615T2 DE 69232615 T DE69232615 T DE 69232615T DE 69232615 T DE69232615 T DE 69232615T DE 69232615 T2 DE69232615 T2 DE 69232615T2
- Authority
- DE
- Germany
- Prior art keywords
- lmwh
- present
- pathological processes
- compositions
- preventing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7024—Esters of saccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL9802891A IL98028A (en) | 1991-05-02 | 1991-05-02 | Pharmaceuticals containing low molecular weight heparin (HWML) |
IL98298A IL98298A0 (en) | 1991-05-28 | 1991-05-28 | Pharmaceutical compositions comprising a heparin derivative |
PCT/US1992/003626 WO1992019249A1 (en) | 1991-05-02 | 1992-05-01 | Compositions for the prevention and/or treatment of pathological processes |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69232615D1 DE69232615D1 (de) | 2002-06-27 |
DE69232615T2 true DE69232615T2 (de) | 2003-01-30 |
Family
ID=26322260
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69232615T Expired - Lifetime DE69232615T2 (de) | 1991-05-02 | 1992-05-01 | Zusammensetzungen zur verhütung und/oder behandlung von pathologischen prozessen |
Country Status (15)
Country | Link |
---|---|
US (3) | US5474987A (de) |
EP (1) | EP0583360B1 (de) |
JP (1) | JPH06507635A (de) |
KR (1) | KR100235782B1 (de) |
AT (1) | ATE217796T1 (de) |
AU (1) | AU668865B2 (de) |
BR (1) | BR9205961A (de) |
CA (1) | CA2102207A1 (de) |
CZ (1) | CZ232593A3 (de) |
DE (1) | DE69232615T2 (de) |
FI (1) | FI934849A (de) |
HU (1) | HUT67136A (de) |
NO (1) | NO933942L (de) |
SK (1) | SK120193A3 (de) |
WO (1) | WO1992019249A1 (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5605938A (en) | 1991-05-31 | 1997-02-25 | Gliatech, Inc. | Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate |
US6750207B1 (en) * | 1992-05-01 | 2004-06-15 | Yeda Research And Development Co. Ltd. | Compositions for the regulation of cytokine activity |
NZ258367A (en) * | 1992-11-10 | 1997-02-24 | Yeda Res & Dev | Oligosaccharide compositions comprising carboxylated and/or sulphated oligosaccharides for use in regulating tnf alpha production |
AU6204594A (en) * | 1993-02-22 | 1994-09-14 | Ulrich-Christoph Von Arnim | Use of heparins for the treatment of inflammatory or immunological diseases |
US5980865A (en) * | 1995-08-18 | 1999-11-09 | Baker Norton Pharmaceuticals, Inc. | Method for treating late phase allergic reactions and inflammatory diseases |
WO1997016556A1 (en) | 1995-10-30 | 1997-05-09 | Massachusetts Institute Of Technology | Rationally designed polysaccharide lyases derived from heparinase i |
DK0946185T4 (da) * | 1996-11-27 | 2010-08-30 | Aventis Pharma Inc | Farmaceutisk præparat, som omfatter en forbindelse med anti-Xa-aktivitet og en blodpladeaggregations antagonistforbindelse |
EP0998941B9 (de) | 1997-07-14 | 2007-03-14 | Takashi Muramatsu | Verwendung von midkin oder von anti-midkin antikörper |
US7056504B1 (en) | 1998-08-27 | 2006-06-06 | Massachusetts Institute Of Technology | Rationally designed heparinases derived from heparinase I and II |
JP2003527822A (ja) | 1998-08-27 | 2003-09-24 | マサチューセッツ インスティテュート オブ テクノロジー | ヘパリナーゼiおよびii由来の合理的に設計されたヘパリナーゼ |
IL127851A0 (en) | 1998-12-30 | 1999-10-28 | Applied Research Systems | Inhibition of TNF activity |
CA2370539C (en) | 1999-04-23 | 2009-01-06 | Massachusetts Institute Of Technology | System and method for notating polymers |
AU782661B2 (en) * | 1999-06-30 | 2005-08-18 | Hamilton Civic Hospitals Research Development, Inc. | Heparin compositions that inhibit clot associated coagulation factors |
JP2003525946A (ja) * | 2000-03-08 | 2003-09-02 | マサチューセッツ インスティテュート オブ テクノロジー | ヘパリナーゼiiiおよびその使用 |
CZ2003961A3 (cs) * | 2000-09-08 | 2003-10-15 | Hamilton Civic Hospitals Research Development, Inc. | Farmaceutický prostředek k inhibici nebo prevenci tvorby či aktivity thrombinu |
CA2422059C (en) | 2000-09-12 | 2012-05-15 | Massachusetts Institute Of Technology | Methods and products related to low molecular weight heparin |
CA2423469A1 (en) | 2000-10-18 | 2002-04-25 | Massachusetts Institute Of Technology | Methods and products related to pulmonary delivery of polysaccharides |
ES2238383T3 (es) * | 2000-12-16 | 2005-09-01 | Aventis Pharma Deutschland Gmbh | Uso de heparina de bajo peso molecular para el tratamiento de la osteoartrosis. |
JP2004535434A (ja) * | 2001-06-25 | 2004-11-25 | デピユイ | 関節炎にかかった関節の処置のためのグリコサミノグリカン類のリポソームカプセル化 |
US20040241689A1 (en) * | 2001-07-31 | 2004-12-02 | Baseman Joel B. | Antigens of and antibodies to translocated molecules of microorganisms and uses thereof |
AU2002322862A1 (en) * | 2001-07-31 | 2003-02-17 | Reddy Us Therapeutics, Inc. | Methods and compositions for diagnosis and treatment of vascular conditions |
US7285536B2 (en) * | 2001-12-05 | 2007-10-23 | Yeda Research And Development Co., Ltd. | Anti-cancer therapeutic compounds |
US20040072796A1 (en) * | 2002-04-18 | 2004-04-15 | Embury Stephen H. | Method and composition for preventing pain in sickle cell patients |
US8071569B2 (en) * | 2002-09-20 | 2011-12-06 | Mousa Shaker A | Oxidized heparin fractions and their use in inhibiting angiogenesis |
WO2004067704A2 (en) * | 2003-01-30 | 2004-08-12 | Prochon Biotech Ltd. | Freeze-dried fibrin matrices and methods for preparation thereof |
WO2005054493A2 (en) * | 2003-06-12 | 2005-06-16 | Mayo Foundation For Medical Education And Research | Altered activity of toll-like receptors |
AU2004252567B2 (en) | 2003-06-27 | 2011-10-06 | Ethicon, Incorporated | Repair and regeneration of ocular tissue using postpartum-derived cells |
US9572840B2 (en) | 2003-06-27 | 2017-02-21 | DePuy Synthes Products, Inc. | Regeneration and repair of neural tissue using postpartum-derived cells |
EP1667633A4 (de) * | 2003-10-01 | 2008-10-08 | Momenta Pharmaceuticals Inc | Polysaccharide zur pulmonalen abgabe von wirkstoffen |
WO2005092348A1 (ja) * | 2004-03-29 | 2005-10-06 | Kringle Pharma Inc. | ヘパリン様オリゴ糖含有hgf産生促進薬剤 |
US8450297B2 (en) * | 2004-08-16 | 2013-05-28 | Massachusetts Institute Of Technology | Rapid two-step synthesis of anti-coagulants |
CA2589041C (en) | 2004-12-23 | 2019-08-20 | Ethicon, Incorporated | Postpartum cells derived from umbilical cord tissue, and methods of making and using the same |
WO2007014049A2 (en) * | 2005-07-22 | 2007-02-01 | The Regents Of The University Of California | Heparin compositions and selectin inhibition |
EP1926459B1 (de) | 2005-09-19 | 2015-01-07 | Histogenics Corporation | Zellunterstützende matrix mit eng definierter, gleichmässig senkrecht und nicht zufällig organisierter porosität und porendichte und verfahren zur herstellung davon |
EP2283045A1 (de) * | 2008-05-20 | 2011-02-16 | Crystal Clear Partnership | Trennung von polysacchariden mittels ladungsdichtegradient |
US10077420B2 (en) | 2014-12-02 | 2018-09-18 | Histogenics Corporation | Cell and tissue culture container |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL61201A (en) * | 1979-10-05 | 1984-09-30 | Choay Sa | Oligosaccharides having no more than 8 saccharide moieties,their obtention from heparin and pharmaceutical compositions containing them |
US4281108A (en) * | 1980-01-28 | 1981-07-28 | Hepar Industries, Inc. | Process for obtaining low molecular weight heparins endowed with elevated pharmacological properties, and product so obtained |
DE3373782D1 (en) * | 1982-12-20 | 1987-10-29 | Harvard College | Inhibition of angiogenesis |
US4916219A (en) * | 1985-03-28 | 1990-04-10 | University Of Iowa Research Foundation | Oligosaccharide heparin fragments as inhibitors of complement cascade |
IT1214609B (it) * | 1985-05-17 | 1990-01-18 | Opocrin Spa | Esosaminoglicani solfati depolimerizzati ad attivita'antitrombotica, fibrinolitica, antinfiammatoria, loro procedimento di preparazione e composizioni farmaceutiche che li contengono. |
US4889808A (en) * | 1985-10-01 | 1989-12-26 | American Home Products | Method of enchancing t-PA and SCU-PA production |
EP0240098A3 (de) * | 1986-04-04 | 1989-05-10 | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo | Oligo und Polysaccharide zur Behandlung von Krankheiten verursacht durch Retroviren |
US4788307A (en) * | 1986-04-30 | 1988-11-29 | Choay S.A. | Oligosaccharidic fractions devoid or practically devoid of antithrombotic activity |
DE3787996T2 (de) * | 1986-05-16 | 1994-03-03 | Italfarmaco Spa | Heparine, frei von E.D.T.A., Fraktionen und Fragmente von Heparin, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, welche diese enthalten. |
WO1988000017A1 (en) * | 1986-06-27 | 1988-01-14 | Boon Corporation Pty. Ltd. | Mat |
IL85145A (en) * | 1987-01-23 | 1994-08-26 | Univ Australian | Anti-metastatic pharmacological or veterinary preparations containing modified herpin with reduced anticoagulant activity |
FR2614026B1 (fr) * | 1987-04-16 | 1992-04-17 | Sanofi Sa | Heparines de bas poids moleculaire, a structure reguliere, leur preparation et leurs applications biologiques |
SE8702254D0 (sv) * | 1987-05-29 | 1987-05-29 | Kabivitrum Ab | Novel heparin derivatives |
AU4426289A (en) * | 1988-10-05 | 1990-05-01 | Nicola Diferrante | Methods for interfering with hiv multiplication and composition for the treatment of aids |
IL88554A0 (en) * | 1988-12-01 | 1989-07-31 | Hadassah Med Org | Compositions containing a compound binding to a heparin receptor |
PT93847A (pt) * | 1989-04-24 | 1990-11-20 | Harvard College | Processo para a preparacao de oligossacaridos de baixo peso molecular derivados de heparina ou de sulfato de heparano despolimerizados e de composicoes farmaceuticas que os contem |
AT500533B8 (de) * | 2000-04-13 | 2007-02-15 | Man Nutzfahrzeuge Ag | Gas- oder trolleybus |
-
1992
- 1992-05-01 KR KR1019930703303A patent/KR100235782B1/ko not_active IP Right Cessation
- 1992-05-01 BR BR9205961A patent/BR9205961A/pt not_active Application Discontinuation
- 1992-05-01 EP EP92911373A patent/EP0583360B1/de not_active Expired - Lifetime
- 1992-05-01 WO PCT/US1992/003626 patent/WO1992019249A1/en active IP Right Grant
- 1992-05-01 AU AU19131/92A patent/AU668865B2/en not_active Ceased
- 1992-05-01 CA CA002102207A patent/CA2102207A1/en not_active Abandoned
- 1992-05-01 AT AT92911373T patent/ATE217796T1/de not_active IP Right Cessation
- 1992-05-01 DE DE69232615T patent/DE69232615T2/de not_active Expired - Lifetime
- 1992-05-01 JP JP4511483A patent/JPH06507635A/ja active Pending
- 1992-05-01 SK SK1201-93A patent/SK120193A3/sk unknown
- 1992-05-01 CZ CS932325A patent/CZ232593A3/cs unknown
- 1992-05-01 HU HU9303110A patent/HUT67136A/hu unknown
-
1993
- 1993-11-01 NO NO933942A patent/NO933942L/no unknown
- 1993-11-02 FI FI934849A patent/FI934849A/fi not_active Application Discontinuation
-
1995
- 1995-02-03 US US08/384,203 patent/US5474987A/en not_active Expired - Lifetime
- 1995-06-01 US US08/457,655 patent/US5686431A/en not_active Expired - Lifetime
-
1997
- 1997-11-07 US US08/966,315 patent/US5908837A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
FI934849A (fi) | 1993-12-31 |
AU668865B2 (en) | 1996-05-23 |
HU9303110D0 (en) | 1994-01-28 |
CA2102207A1 (en) | 1992-11-03 |
JPH06507635A (ja) | 1994-09-01 |
US5474987A (en) | 1995-12-12 |
BR9205961A (pt) | 1994-07-26 |
EP0583360A4 (de) | 1994-04-06 |
WO1992019249A1 (en) | 1992-11-12 |
HUT67136A (en) | 1995-02-28 |
DE69232615D1 (de) | 2002-06-27 |
EP0583360B1 (de) | 2002-05-22 |
NO933942L (no) | 1993-12-14 |
ATE217796T1 (de) | 2002-06-15 |
FI934849A0 (fi) | 1993-11-02 |
NO933942D0 (no) | 1993-11-01 |
US5686431A (en) | 1997-11-11 |
SK120193A3 (en) | 1994-07-06 |
US5908837A (en) | 1999-06-01 |
EP0583360A1 (de) | 1994-02-23 |
AU1913192A (en) | 1992-12-21 |
CZ232593A3 (en) | 1994-07-13 |
KR100235782B1 (ko) | 1999-12-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |