DE69325794T2 - Humanes serum albumin, herstellung und verwendung - Google Patents

Humanes serum albumin, herstellung und verwendung

Info

Publication number
DE69325794T2
DE69325794T2 DE69325794T DE69325794T DE69325794T2 DE 69325794 T2 DE69325794 T2 DE 69325794T2 DE 69325794 T DE69325794 T DE 69325794T DE 69325794 T DE69325794 T DE 69325794T DE 69325794 T2 DE69325794 T2 DE 69325794T2
Authority
DE
Germany
Prior art keywords
pct
production
serum albumin
sec
date
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69325794T
Other languages
English (en)
Other versions
DE69325794D1 (de
Inventor
Jerome Becquart
Reinhard Fleer
Gerard Jung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Albumedix Ltd
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9425981&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69325794(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Application granted granted Critical
Publication of DE69325794D1 publication Critical patent/DE69325794D1/de
Publication of DE69325794T2 publication Critical patent/DE69325794T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
DE69325794T 1992-01-27 1993-01-26 Humanes serum albumin, herstellung und verwendung Expired - Lifetime DE69325794T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9200807A FR2686620B1 (fr) 1992-01-27 1992-01-27 Serum-albumine humaine, preparation et utilisation.
PCT/FR1993/000072 WO1993015204A1 (fr) 1992-01-27 1993-01-26 Serum-albumine humaine, preparation et utilisation

Publications (2)

Publication Number Publication Date
DE69325794D1 DE69325794D1 (de) 1999-09-02
DE69325794T2 true DE69325794T2 (de) 2000-01-13

Family

ID=9425981

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69325794T Expired - Lifetime DE69325794T2 (de) 1992-01-27 1993-01-26 Humanes serum albumin, herstellung und verwendung

Country Status (16)

Country Link
US (1) US5612196A (de)
EP (1) EP0625202B1 (de)
JP (1) JP3390990B2 (de)
AT (1) ATE182623T1 (de)
AU (1) AU686996B2 (de)
CA (1) CA2126356C (de)
DE (1) DE69325794T2 (de)
DK (1) DK0625202T3 (de)
ES (1) ES2137251T3 (de)
FI (1) FI943512A0 (de)
FR (1) FR2686620B1 (de)
GR (1) GR3030873T3 (de)
HU (1) HU218353B (de)
NO (1) NO310418B1 (de)
NZ (1) NZ249153A (de)
WO (1) WO1993015204A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
US5728553A (en) * 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
CA2136564C (en) * 1993-11-26 2008-04-08 Kaoru Kobayashi Process for producing human serum albumin
GB9526733D0 (en) 1995-12-30 1996-02-28 Delta Biotechnology Ltd Fusion proteins
GB9902000D0 (en) * 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
AU2001264563A1 (en) 2000-04-12 2001-10-30 Human Genome Sciences, Inc. Albumin fusion proteins
US6946134B1 (en) 2000-04-12 2005-09-20 Human Genome Sciences, Inc. Albumin fusion proteins
US6762053B2 (en) * 2000-06-09 2004-07-13 Vitrolife, Inc. Mammalian gamete and embryo culture media and culture media supplements
US20060084794A1 (en) * 2001-04-12 2006-04-20 Human Genome Sciences, Inc. Albumin fusion proteins
US7507413B2 (en) 2001-04-12 2009-03-24 Human Genome Sciences, Inc. Albumin fusion proteins
US20050244931A1 (en) * 2001-04-12 2005-11-03 Human Genome Sciences, Inc. Albumin fusion proteins
US20050054051A1 (en) * 2001-04-12 2005-03-10 Human Genome Sciences, Inc. Albumin fusion proteins
AU2002332041A1 (en) * 2001-10-05 2003-04-22 Human Genome Sciences, Inc. Albumin fusion proteins
EP1997829A1 (de) 2001-12-21 2008-12-03 Human Genome Sciences, Inc. Albumin Fusionsproteine
CA2484556A1 (en) 2001-12-21 2003-07-24 Human Genome Sciences, Inc. Albumin fusion proteins
CA2513213C (en) 2003-01-22 2013-07-30 Human Genome Sciences, Inc. Albumin fusion proteins
PL1729795T3 (pl) * 2004-02-09 2016-08-31 Human Genome Sciences Inc Białka fuzyjne albuminy
US20090280534A1 (en) * 2004-12-22 2009-11-12 Novozymes A/S Recombinant Production of Serum Albumin
CN102282168A (zh) * 2008-11-18 2011-12-14 梅里麦克制药股份有限公司 人血清白蛋白接头以及其结合物
CN102127164B (zh) 2010-12-20 2013-01-30 武汉禾元生物科技有限公司 一种从水稻种子中提取重组人血清白蛋白的方法
CN102532254B (zh) 2010-12-24 2015-06-24 武汉禾元生物科技股份有限公司 一种从水稻种子中分离纯化重组人血清白蛋白的方法
EP2729492B1 (de) 2011-07-05 2019-01-02 Albumedix Ltd Albuminformulierung und verwendung
US9345766B2 (en) 2012-08-30 2016-05-24 Merrimack Pharmaceuticals, Inc. Combination therapies comprising anti-ERBB3 agents
CN103880947B (zh) 2012-12-21 2016-01-13 武汉禾元生物科技股份有限公司 一种分离纯化高纯度重组人血清白蛋白的层析方法
PT3240798T (pt) 2015-01-01 2020-05-07 Shilpa Medicare Ltd Novo método para purificação eficiente de albumina do soro humana
US11739166B2 (en) 2020-07-02 2023-08-29 Davol Inc. Reactive polysaccharide-based hemostatic agent
WO2024018452A1 (en) 2022-07-18 2024-01-25 Yeda Research And Development Co. Ltd. Albumin protein variants, production thereof and uses of same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE405549B (sv) * 1975-10-09 1978-12-18 Pharmacia Fine Chemicals Ab Forfarande for isolering av albumin ur plasmaprodukter genom kromatografisk fraktionering
NL7708005A (nl) * 1976-07-22 1978-01-24 Monsanto Co Werkwijze voor de bereiding van serumalbumine.
JPS62294621A (ja) * 1986-06-13 1987-12-22 Green Cross Corp:The アルブミンの回収方法
IL89992A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Expression of human serum albumin in methylotrophic yeasts
FR2649991B2 (fr) * 1988-08-05 1994-03-04 Rhone Poulenc Sante Utilisation de derives stables du plasmide pkd1 pour l'expression et la secretion de proteines heterologues dans les levures du genre kluyveromyces
FR2635115B1 (fr) * 1988-08-05 1992-04-03 Rhone Poulenc Sante Procede de preparation de la serum albumine humaine a partir d'une levure
GB8923521D0 (en) * 1989-10-18 1989-12-06 Delta Biotechnology Ltd Yeast promoter
JP3230091B2 (ja) * 1990-06-25 2001-11-19 ウェルファイド株式会社 ヒト血清アルブミンの着色抑制方法
US5330901A (en) * 1991-04-26 1994-07-19 Research Corporation Technologies, Inc. Expression of human serum albumin in Pichia pastoris
FR2677996B1 (fr) * 1991-06-21 1993-08-27 Rhone Poulenc Rorer Sa Vecteurs de clonage et/ou d'expression preparation et utilisation.

Also Published As

Publication number Publication date
NO942780D0 (no) 1994-07-26
CA2126356C (fr) 2003-03-18
FI943512A (fi) 1994-07-26
AU686996B2 (en) 1998-02-19
FR2686620A1 (fr) 1993-07-30
ES2137251T3 (es) 1999-12-16
HU9401960D0 (en) 1994-09-28
EP0625202B1 (de) 1999-07-28
US5612196A (en) 1997-03-18
FI943512A0 (fi) 1994-07-26
HUT70570A (en) 1995-10-30
GR3030873T3 (en) 1999-11-30
DK0625202T3 (da) 2000-02-28
NO310418B1 (no) 2001-07-02
JP3390990B2 (ja) 2003-03-31
CA2126356A1 (fr) 1993-08-05
HU218353B (hu) 2000-08-28
DE69325794D1 (de) 1999-09-02
AU3503893A (en) 1993-09-01
EP0625202A1 (de) 1994-11-23
ATE182623T1 (de) 1999-08-15
NZ249153A (en) 1996-03-26
FR2686620B1 (fr) 1995-06-23
WO1993015204A1 (fr) 1993-08-05
NO942780L (no) 1994-07-26
JPH07503137A (ja) 1995-04-06

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8327 Change in the person/name/address of the patent owner

Owner name: NOVOZYMES BIOPHARMA UK LIMITED, NOTTINGHAM, GB