DE69331526T2 - Adenovirus gelenkter gen-transfer zum herz- und glatten vaskularen muskel - Google Patents

Adenovirus gelenkter gen-transfer zum herz- und glatten vaskularen muskel

Info

Publication number
DE69331526T2
DE69331526T2 DE69331526T DE69331526T DE69331526T2 DE 69331526 T2 DE69331526 T2 DE 69331526T2 DE 69331526 T DE69331526 T DE 69331526T DE 69331526 T DE69331526 T DE 69331526T DE 69331526 T2 DE69331526 T2 DE 69331526T2
Authority
DE
Germany
Prior art keywords
adenovirus
heart
guided
vascular muscle
smooth vascular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69331526T
Other languages
English (en)
Other versions
DE69331526D1 (de
Inventor
M Leiden
Eliav Barr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arch Development Corp
Original Assignee
Arch Development Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25525197&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69331526(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Arch Development Corp filed Critical Arch Development Corp
Publication of DE69331526D1 publication Critical patent/DE69331526D1/de
Application granted granted Critical
Publication of DE69331526T2 publication Critical patent/DE69331526T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4707Muscular dystrophy
    • C07K14/4708Duchenne dystrophy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/008Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
DE69331526T 1992-11-18 1993-11-16 Adenovirus gelenkter gen-transfer zum herz- und glatten vaskularen muskel Expired - Fee Related DE69331526T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97749692A 1992-11-18 1992-11-18
PCT/US1993/011133 WO1994011506A1 (en) 1992-11-18 1993-11-16 Adenovirus-mediated gene transfer to cardiac and vascular smooth muscle

Publications (2)

Publication Number Publication Date
DE69331526D1 DE69331526D1 (de) 2002-03-14
DE69331526T2 true DE69331526T2 (de) 2002-10-24

Family

ID=25525197

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69333886T Expired - Fee Related DE69333886T2 (de) 1992-11-18 1993-11-16 Adenovirus-gelenkter Gen-Transfer zum Herz-und glattem vaskulären Muskel
DE69331526T Expired - Fee Related DE69331526T2 (de) 1992-11-18 1993-11-16 Adenovirus gelenkter gen-transfer zum herz- und glatten vaskularen muskel

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69333886T Expired - Fee Related DE69333886T2 (de) 1992-11-18 1993-11-16 Adenovirus-gelenkter Gen-Transfer zum Herz-und glattem vaskulären Muskel

Country Status (8)

Country Link
US (2) US6297220B1 (de)
EP (3) EP0957172B1 (de)
JP (4) JPH08506008A (de)
AT (2) ATE307212T1 (de)
AU (1) AU694097B2 (de)
CA (1) CA2149771A1 (de)
DE (2) DE69333886T2 (de)
WO (1) WO1994011506A1 (de)

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Also Published As

Publication number Publication date
JP2004313198A (ja) 2004-11-11
JP2003102474A (ja) 2003-04-08
EP0668913A1 (de) 1995-08-30
EP0957172A2 (de) 1999-11-17
EP0668913B1 (de) 2002-01-30
CA2149771A1 (en) 1994-05-26
AU694097B2 (en) 1998-07-16
AU5609394A (en) 1994-06-08
JP2006212034A (ja) 2006-08-17
JPH08506008A (ja) 1996-07-02
DE69331526D1 (de) 2002-03-14
EP1321526A2 (de) 2003-06-25
US6436907B1 (en) 2002-08-20
EP0957172B1 (de) 2005-10-19
DE69333886T2 (de) 2006-07-27
WO1994011506A1 (en) 1994-05-26
US6297220B1 (en) 2001-10-02
EP0957172A3 (de) 2000-03-15
ATE212665T1 (de) 2002-02-15
DE69333886D1 (de) 2006-03-02
ATE307212T1 (de) 2005-11-15
EP1321526A3 (de) 2003-07-02

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