DE69427807T2 - Hemmung von Hirsutismus und Alopecia bei Frauen - Google Patents

Hemmung von Hirsutismus und Alopecia bei Frauen

Info

Publication number
DE69427807T2
DE69427807T2 DE69427807T DE69427807T DE69427807T2 DE 69427807 T2 DE69427807 T2 DE 69427807T2 DE 69427807 T DE69427807 T DE 69427807T DE 69427807 T DE69427807 T DE 69427807T DE 69427807 T2 DE69427807 T2 DE 69427807T2
Authority
DE
Germany
Prior art keywords
alopecia
women
hirsutism
inhibition
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69427807T
Other languages
English (en)
Other versions
DE69427807D1 (de
Inventor
George Joseph Cullinan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE69427807D1 publication Critical patent/DE69427807D1/de
Publication of DE69427807T2 publication Critical patent/DE69427807T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
DE69427807T 1993-12-21 1994-12-19 Hemmung von Hirsutismus und Alopecia bei Frauen Expired - Fee Related DE69427807T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/171,089 US5574048A (en) 1993-12-21 1993-12-21 Methods of inhibiting hirsutism and alopecia in women

Publications (2)

Publication Number Publication Date
DE69427807D1 DE69427807D1 (de) 2001-08-30
DE69427807T2 true DE69427807T2 (de) 2001-12-06

Family

ID=22622479

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69427807T Expired - Fee Related DE69427807T2 (de) 1993-12-21 1994-12-19 Hemmung von Hirsutismus und Alopecia bei Frauen

Country Status (22)

Country Link
US (2) US5574048A (de)
EP (1) EP0659414B1 (de)
JP (1) JPH07215864A (de)
KR (1) KR950016728A (de)
CN (1) CN1107703A (de)
AT (1) ATE203406T1 (de)
AU (1) AU690162B2 (de)
CA (1) CA2138498A1 (de)
CZ (1) CZ321394A3 (de)
DE (1) DE69427807T2 (de)
DK (1) DK0659414T3 (de)
ES (1) ES2157961T3 (de)
GR (1) GR3036977T3 (de)
HU (1) HUT71479A (de)
IL (1) IL112040A0 (de)
NO (1) NO944920L (de)
NZ (1) NZ270171A (de)
PH (1) PH31440A (de)
PT (1) PT659414E (de)
RU (1) RU94044457A (de)
SI (1) SI0659414T1 (de)
ZA (1) ZA9410092B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965551A (en) * 1996-02-21 1999-10-12 North Carolina State University Method of treating alopecia
IL120266A (en) 1996-02-28 2005-05-17 Pfizer Use of estrogen antagonists and estrogen agonists in the preparation of medicaments for inhibiting pathological conditions
TW442286B (en) * 1996-02-28 2001-06-23 Pfizer New therapeutic uses of estrogen agonists
JP5005127B2 (ja) 1999-05-04 2012-08-22 ストラカン・インターナショナル・リミテッド アンドロゲングリコシド及びそのアンドロゲン作用活性
US20060263452A1 (en) * 2005-05-17 2006-11-23 Alwyn Dowell Topical composition containing essential oils
EP2459187B1 (de) 2009-07-29 2021-01-06 Olsen, Elise Zusammensetzungen und verfahren zur hemmung von haarwachstum

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4418068A (en) * 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
US4380635A (en) * 1981-04-03 1983-04-19 Eli Lilly And Company Synthesis of acylated benzothiophenes
US4859585A (en) * 1986-04-17 1989-08-22 Trustees Of Tufts College In-vitro methods for identifying compositions which are agonists and antagonists of estrogens
US5075321A (en) * 1987-03-24 1991-12-24 University Of Pennsylvania Methods of treating diseases characterized by interactions of IgG-containing immune complexes with macrophage Fc receptors using antiestrogenic benzothiophenes
US5395842A (en) * 1988-10-31 1995-03-07 Endorecherche Inc. Anti-estrogenic compounds and compositions
JP3157882B2 (ja) * 1991-11-15 2001-04-16 帝国臓器製薬株式会社 新規なベンゾチオフエン誘導体

Also Published As

Publication number Publication date
NO944920L (no) 1995-06-22
NO944920D0 (no) 1994-12-19
JPH07215864A (ja) 1995-08-15
GR3036977T3 (en) 2002-01-31
HU9403665D0 (en) 1995-02-28
CA2138498A1 (en) 1995-06-22
EP0659414A3 (de) 1995-09-06
AU8155094A (en) 1995-06-29
EP0659414B1 (de) 2001-07-25
PH31440A (en) 1998-11-03
PT659414E (pt) 2001-11-30
KR950016728A (ko) 1995-07-20
US5574048A (en) 1996-11-12
SI0659414T1 (en) 2001-12-31
US5686468A (en) 1997-11-11
ZA9410092B (en) 1996-06-19
ES2157961T3 (es) 2001-09-01
HUT71479A (en) 1995-11-28
ATE203406T1 (de) 2001-08-15
NZ270171A (en) 1996-08-27
AU690162B2 (en) 1998-04-23
IL112040A0 (en) 1995-03-15
CZ321394A3 (en) 1995-08-16
DK0659414T3 (da) 2001-09-24
RU94044457A (ru) 1996-10-10
DE69427807D1 (de) 2001-08-30
CN1107703A (zh) 1995-09-06
EP0659414A2 (de) 1995-06-28

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DE69427807D1 (de) Hemmung von Hirsutismus und Alopecia bei Frauen

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee