DE69428891T2 - VERFAHREN ZUR VERBINDUNG VON LIGANDEN IN EINEM PORÖSEN TRÄGER (e.g.AZLAKTON) UND DESSEN ANWENDUNGEN - Google Patents

VERFAHREN ZUR VERBINDUNG VON LIGANDEN IN EINEM PORÖSEN TRÄGER (e.g.AZLAKTON) UND DESSEN ANWENDUNGEN

Info

Publication number
DE69428891T2
DE69428891T2 DE69428891T DE69428891T DE69428891T2 DE 69428891 T2 DE69428891 T2 DE 69428891T2 DE 69428891 T DE69428891 T DE 69428891T DE 69428891 T DE69428891 T DE 69428891T DE 69428891 T2 DE69428891 T2 DE 69428891T2
Authority
DE
Germany
Prior art keywords
azlakton
applications
porous carrier
connecting ligands
ligands
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69428891T
Other languages
English (en)
Other versions
DE69428891D1 (de
Inventor
William Velander
S Milbrath
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VIRGINIA S CT FOR INNOVATIVE T
3M Co
Original Assignee
VIRGINIA S CT FOR INNOVATIVE T
Minnesota Mining and Manufacturing Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by VIRGINIA S CT FOR INNOVATIVE T, Minnesota Mining and Manufacturing Co filed Critical VIRGINIA S CT FOR INNOVATIVE T
Publication of DE69428891D1 publication Critical patent/DE69428891D1/de
Application granted granted Critical
Publication of DE69428891T2 publication Critical patent/DE69428891T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6464—Protein C (3.4.21.69)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
DE69428891T 1993-03-29 1994-02-18 VERFAHREN ZUR VERBINDUNG VON LIGANDEN IN EINEM PORÖSEN TRÄGER (e.g.AZLAKTON) UND DESSEN ANWENDUNGEN Expired - Fee Related DE69428891T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3864593A 1993-03-29 1993-03-29
PCT/US1994/003927 WO1994022918A1 (en) 1993-03-29 1994-02-18 Method of coupling ligands within porous supports (p.e. azlactone) and uses thereof

Publications (2)

Publication Number Publication Date
DE69428891D1 DE69428891D1 (de) 2001-12-06
DE69428891T2 true DE69428891T2 (de) 2002-06-27

Family

ID=21901089

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69428891T Expired - Fee Related DE69428891T2 (de) 1993-03-29 1994-02-18 VERFAHREN ZUR VERBINDUNG VON LIGANDEN IN EINEM PORÖSEN TRÄGER (e.g.AZLAKTON) UND DESSEN ANWENDUNGEN

Country Status (8)

Country Link
US (1) US5907016A (de)
EP (1) EP0693085B1 (de)
JP (1) JP3607289B2 (de)
KR (1) KR960701099A (de)
CA (1) CA2158056A1 (de)
DE (1) DE69428891T2 (de)
NO (1) NO953836L (de)
WO (1) WO1994022918A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9425138D0 (en) 1994-12-12 1995-02-08 Dynal As Isolation of nucleic acid
US6379952B1 (en) 1999-02-01 2002-04-30 3M Innovative Properties Company Method for cell selection utilizing azlactone-functional supports
US6787635B2 (en) * 2001-04-05 2004-09-07 3M Innovative Properties Company Solid phase synthesis supports and methods
CA2473376A1 (en) 2002-01-16 2003-07-31 Dynal Biotech Asa Method for isolating nucleic acids and protein from a single sample
US20030203504A1 (en) * 2002-04-26 2003-10-30 John Hefti Diffusion-based system and method for detecting and monitoring activity of biologic and chemical species
GB0229287D0 (en) * 2002-12-16 2003-01-22 Dna Res Innovations Ltd Polyfunctional reagents
JP5032324B2 (ja) * 2004-10-01 2012-09-26 スリーエム イノベイティブ プロパティズ カンパニー 複合濾過物品
US7645312B2 (en) * 2004-10-15 2010-01-12 3M Innovative Properties Company Pleated multi-layer filter media and cartridge
AU2005317279C1 (en) * 2004-12-14 2014-07-17 Cytiva Bioprocess R&D Ab Purification of immunoglobulins
US8728828B2 (en) 2004-12-22 2014-05-20 Ge Healthcare Bio-Sciences Ab Purification of immunoglobulins
WO2008026953A1 (en) * 2006-08-28 2008-03-06 Akademia Medyczna Im. Piastow Slaskich We Wroclawiu A system and method for the extra-corporeal purification of blood of pathogenic enzymes
GB201703116D0 (en) * 2017-02-27 2017-04-12 Ge Healthcare Bioprocess R&D Ab A seperation matrix and a method of seperating antibodies

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS635133B2 (de) * 1978-01-24 1988-02-02 Paburitsuku Herusu Raboratarii Saauisu Boodo
US4704366A (en) * 1984-06-22 1987-11-03 Bio-Rad Laboratories, Inc. Process for binding IgG to protein A
US4791069A (en) * 1984-09-21 1988-12-13 Ortho Diagnostic Systems Inc. Methods for attaching ligands or anti-ligands to a solid phase
CS253971B1 (en) * 1984-12-11 1987-12-17 Peter Hermann Production method of high active biological effective compounds immobilized on carrier
DE3515252C2 (de) * 1985-04-27 1994-02-24 Roehm Gmbh Verfahren zur Immobilisierung gelöster Eiweißstoffe
US4822747A (en) * 1986-12-09 1989-04-18 Miles Inc. Polyacrylamide gel particles having hapten moieties bound thereto as immunoassay reagent
US4968742A (en) * 1987-11-09 1990-11-06 Miles Inc. Preparation of ligand-polymer conjugate having a controlled number of introduced ligands
AU3047989A (en) * 1988-02-11 1989-09-06 Cuno Incorporated Affinity matrices of modified polysaccharide supports
US5013795A (en) * 1989-04-10 1991-05-07 Minnesota Mining And Manufacturing Company Azlactone graft copolymers
US5039813A (en) * 1990-06-29 1991-08-13 Polaroid Corporation 2-(4-alkenylphenyl)-5-oxazolones and polymers thereof
US5200471A (en) * 1990-11-05 1993-04-06 Minnesota Mining And Manufacturing Company Biomolecules covalently immobilized with a high bound specific biological activity and method of preparing same
US5120833A (en) * 1991-03-15 1992-06-09 Alexander Kaplan Method of producing grafts
US5219749A (en) * 1991-10-09 1993-06-15 Institute For Molecular Biology & Biotechnology/Forth Process for isolating and preparing purified chitin deacetylase
US5993935A (en) * 1991-10-11 1999-11-30 3M Innovative Properties Company Covalently reactive particles incorporated in a continous porous matrix
DE4310964A1 (de) * 1992-04-16 1993-10-21 Merck Patent Gmbh Aktivierte Trägermaterialien, ihre Herstellung und Verwendung

Also Published As

Publication number Publication date
EP0693085B1 (de) 2001-10-31
WO1994022918A1 (en) 1994-10-13
JPH09506067A (ja) 1997-06-17
EP0693085A1 (de) 1996-01-24
US5907016A (en) 1999-05-25
KR960701099A (ko) 1996-02-24
CA2158056A1 (en) 1994-10-13
DE69428891D1 (de) 2001-12-06
JP3607289B2 (ja) 2005-01-05
NO953836D0 (no) 1995-09-28
NO953836L (no) 1995-11-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee