DE69429265D1 - Medizinabgabe - Google Patents

Medizinabgabe

Info

Publication number
DE69429265D1
DE69429265D1 DE69429265T DE69429265T DE69429265D1 DE 69429265 D1 DE69429265 D1 DE 69429265D1 DE 69429265 T DE69429265 T DE 69429265T DE 69429265 T DE69429265 T DE 69429265T DE 69429265 D1 DE69429265 D1 DE 69429265D1
Authority
DE
Germany
Prior art keywords
medical supply
medical
supply
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69429265T
Other languages
English (en)
Other versions
DE69429265T2 (de
Inventor
A Sahatjian
J Barry
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston Scientific Corp
Original Assignee
Boston Scientific Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Scientific Corp filed Critical Boston Scientific Corp
Publication of DE69429265D1 publication Critical patent/DE69429265D1/de
Application granted granted Critical
Publication of DE69429265T2 publication Critical patent/DE69429265T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/104Balloon catheters used for angioplasty
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49Urokinase; Tissue plasminogen activator
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08Materials for coatings
    • A61L29/085Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/145Hydrogels or hydrocolloids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/145Hydrogels or hydrocolloids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005Use of materials characterised by their function or physical properties
    • A61L33/0011Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0023Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using a quaternized group or a protonated amine group of the substrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005Use of materials characterised by their function or physical properties
    • A61L33/0011Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0029Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using an intermediate layer of polymer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/04Tracheal tubes
    • A61M16/0475Tracheal tubes having openings in the tube
    • A61M16/0477Tracheal tubes having openings in the tube with incorporated means for delivering or removing fluids
    • A61M16/0481Tracheal tubes having openings in the tube with incorporated means for delivering or removing fluids through the cuff wall
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M25/0045Catheters; Hollow probes characterised by structural features multi-layered, e.g. coated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004Rounded shapes, e.g. with rounded corners
    • A61F2230/0013Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067Means for introducing or releasing pharmaceutical products into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A61L2300/256Antibodies, e.g. immunoglobulins, vaccines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/258Genetic materials, DNA, RNA, genes, vectors, e.g. plasmids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/42Anti-thrombotic agents, anticoagulants, anti-platelet agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45Mixtures of two or more drugs, e.g. synergistic mixtures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602Type of release, e.g. controlled, sustained, slow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/62Encapsulated active agents, e.g. emulsified droplets
    • A61L2300/622Microcapsules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M25/0045Catheters; Hollow probes characterised by structural features multi-layered, e.g. coated
    • A61M2025/0046Coatings for improving slidability
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M2025/0057Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • A61M2025/09175Guide wires having specific characteristics at the distal tip
    • A61M2025/09183Guide wires having specific characteristics at the distal tip having tools at the distal tip
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/105Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/1086Balloon catheters with special features or adapted for special applications having a special balloon surface topography, e.g. pores, protuberances, spikes or grooves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0266Shape memory materials
DE69429265T 1993-07-23 1994-07-25 Medizinabgabe Expired - Lifetime DE69429265T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/097,248 US5674192A (en) 1990-12-28 1993-07-23 Drug delivery
PCT/US1994/008394 WO1995003083A1 (en) 1993-07-23 1994-07-25 Drug delivery

Publications (2)

Publication Number Publication Date
DE69429265D1 true DE69429265D1 (de) 2002-01-10
DE69429265T2 DE69429265T2 (de) 2002-08-22

Family

ID=22262447

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69429265T Expired - Lifetime DE69429265T2 (de) 1993-07-23 1994-07-25 Medizinabgabe

Country Status (6)

Country Link
US (3) US5674192A (de)
EP (1) EP0708671B1 (de)
JP (1) JPH09500561A (de)
CA (1) CA2166101C (de)
DE (1) DE69429265T2 (de)
WO (1) WO1995003083A1 (de)

Families Citing this family (540)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5674192A (en) * 1990-12-28 1997-10-07 Boston Scientific Corporation Drug delivery
US5843089A (en) * 1990-12-28 1998-12-01 Boston Scientific Corporation Stent lining
US6004346A (en) * 1990-02-28 1999-12-21 Medtronic, Inc. Intralumenal drug eluting prosthesis
US5545208A (en) * 1990-02-28 1996-08-13 Medtronic, Inc. Intralumenal drug eluting prosthesis
US6524274B1 (en) * 1990-12-28 2003-02-25 Scimed Life Systems, Inc. Triggered release hydrogel drug delivery system
US5634901A (en) * 1992-11-02 1997-06-03 Localmed, Inc. Method of using a catheter sleeve
US20020055710A1 (en) * 1998-04-30 2002-05-09 Ronald J. Tuch Medical device for delivering a therapeutic agent and method of preparation
JP3333211B2 (ja) * 1994-01-26 2002-10-15 レイリー,マーク・エイ 骨の治療に関する外科的方法で使用される、改良に係る拡張可能な装置
US20030229372A1 (en) * 1994-01-26 2003-12-11 Kyphon Inc. Inflatable device for use in surgical protocols relating to treatment of fractured or diseased bone
EP0804249A2 (de) * 1994-03-15 1997-11-05 Brown University Research Foundation Polymeres system zur freisetzung von genen
FR2722413B1 (fr) * 1994-07-13 1997-02-07 Marian Devonec Implant therapeutique destine au traitement cytoreducteur selectif de l'obstruction d'une lumiere ou voie naturelle d'un corps humain ou animal
US6558798B2 (en) 1995-02-22 2003-05-06 Scimed Life Systems, Inc. Hydrophilic coating and substrates coated therewith having enhanced durability and lubricity
US6231600B1 (en) 1995-02-22 2001-05-15 Scimed Life Systems, Inc. Stents with hybrid coating for medical devices
US5885971A (en) * 1995-03-24 1999-03-23 The Regents Of The University Of California Gene therapy by secretory gland expression
US5922687A (en) * 1995-05-04 1999-07-13 Board Of Trustees Of The Leland Stanford Junior University Intracellular delivery of nucleic acids using pressure
US7896914B2 (en) 1995-06-07 2011-03-01 Cook Incorporated Coated implantable medical device
US7550005B2 (en) 1995-06-07 2009-06-23 Cook Incorporated Coated implantable medical device
US6774278B1 (en) 1995-06-07 2004-08-10 Cook Incorporated Coated implantable medical device
US7611533B2 (en) * 1995-06-07 2009-11-03 Cook Incorporated Coated implantable medical device
US5830879A (en) * 1995-10-02 1998-11-03 St. Elizabeth's Medical Center Of Boston, Inc. Treatment of vascular injury using vascular endothelial growth factor
US6379966B2 (en) * 1999-02-26 2002-04-30 Mirus Corporation Intravascular delivery of non-viral nucleic acid
US20020001574A1 (en) * 1995-12-13 2002-01-03 Jon A. Woiff Process of delivering a polynucleotide to a muscle cell via the vascular system
WO1997029701A1 (en) 1996-02-15 1997-08-21 Biosense Inc. Catheter based surgery
US5643279A (en) * 1996-03-12 1997-07-01 Cordis Corporation Method of catheter balloon manufacture and use
US6958059B2 (en) 1996-05-20 2005-10-25 Medtronic Ave, Inc. Methods and apparatuses for drug delivery to an intravascular occlusion
US6143037A (en) * 1996-06-12 2000-11-07 The Regents Of The University Of Michigan Compositions and methods for coating medical devices
US6443974B1 (en) * 1996-07-28 2002-09-03 Biosense, Inc. Electromagnetic cardiac biostimulation
US6451044B1 (en) 1996-09-20 2002-09-17 Board Of Regents, The University Of Texas System Method and apparatus for heating inflammed tissue
US6387700B1 (en) * 1996-11-04 2002-05-14 The Reagents Of The University Of Michigan Cationic peptides, Cys-Trp-(LYS)n, for gene delivery
US5833651A (en) * 1996-11-08 1998-11-10 Medtronic, Inc. Therapeutic intraluminal stents
US5776097A (en) * 1996-12-19 1998-07-07 University Of California At Los Angeles Method and device for treating intracranial vascular aneurysms
EP0850607A1 (de) * 1996-12-31 1998-07-01 Cordis Corporation Klappenprothese zur Implantation in Körperkanälen
US6494861B1 (en) 1997-01-15 2002-12-17 Boston Scientific Corporation Drug delivery system
US5868719A (en) * 1997-01-15 1999-02-09 Boston Scientific Corporation Drug delivery balloon catheter device
US6231495B1 (en) 1997-04-26 2001-05-15 Universitat Karlsruhe Radiation emitting, elastic hose for the endovascular therapy
US5879697A (en) * 1997-04-30 1999-03-09 Schneider Usa Inc Drug-releasing coatings for medical devices
US6635027B1 (en) 1997-05-19 2003-10-21 Micro Therepeutics, Inc. Method and apparatus for intramural delivery of a substance
EP0986402A2 (de) 1997-06-06 2000-03-22 Battelle Memorial Institute Reversibles gelbindendes copolymer und verfahren
US6203536B1 (en) 1997-06-17 2001-03-20 Medtronic, Inc. Medical device for delivering a therapeutic substance and method therefor
US20090239940A1 (en) * 1997-07-22 2009-09-24 Del Monte Federica Treating heart failure and ventricular arrhythmias
US6306166B1 (en) 1997-08-13 2001-10-23 Scimed Life Systems, Inc. Loading and release of water-insoluble drugs
EP0980280B1 (de) 1997-10-01 2005-02-09 Medtronic Ave, Inc. Wirstoffabgabe und gentherapiesystem
US6485514B1 (en) 1997-12-12 2002-11-26 Supergen, Inc. Local delivery of therapeutic agents
DE69838526T2 (de) 1998-02-05 2008-07-03 Biosense Webster, Inc., Diamond Bar Gerät zum Freisetzen eines Medikaments im Herzen
US20030113303A1 (en) * 1998-02-05 2003-06-19 Yitzhack Schwartz Homing of embryonic stem cells to a target zone in tissue using active therapeutics or substances
US6372720B1 (en) 1998-02-05 2002-04-16 Kenneth J. Longmuir Liposome fusion and delivery vehicle
US20030129750A1 (en) * 1998-02-05 2003-07-10 Yitzhack Schwartz Homing of donor cells to a target zone in tissue using active therapeutics or substances
AU2794399A (en) * 1998-03-06 1999-09-20 University Of Florida Medical device utilizing hydrogel materials
WO1999049908A1 (en) 1998-03-31 1999-10-07 University Of Cincinnati Temperature controlled solute delivery system
US7713297B2 (en) 1998-04-11 2010-05-11 Boston Scientific Scimed, Inc. Drug-releasing stent with ceramic-containing layer
US6364856B1 (en) 1998-04-14 2002-04-02 Boston Scientific Corporation Medical device with sponge coating for controlled drug release
US6395253B2 (en) 1998-04-23 2002-05-28 The Regents Of The University Of Michigan Microspheres containing condensed polyanionic bioactive agents and methods for their production
US6013099A (en) 1998-04-29 2000-01-11 Medtronic, Inc. Medical device for delivering a water-insoluble therapeutic salt or substance
DE19819426A1 (de) * 1998-04-30 1999-11-11 Christoph Hehrlein Katheter und Gefäßstütze, insbesondere zur kombinierten, radioaktiven Strahlen- und Medikamententherapie sowie Verfahren zu ihrer Herstellung
US6206914B1 (en) 1998-04-30 2001-03-27 Medtronic, Inc. Implantable system with drug-eluting cells for on-demand local drug delivery
US6200477B1 (en) * 1998-05-06 2001-03-13 Alltech Associates, Inc. Continuously regenerated and integrated suppressor and detector for suppressed ion chromatography and method
US8177743B2 (en) 1998-05-18 2012-05-15 Boston Scientific Scimed, Inc. Localized delivery of drug agents
US6280411B1 (en) * 1998-05-18 2001-08-28 Scimed Life Systems, Inc. Localized delivery of drug agents
US6206283B1 (en) * 1998-12-23 2001-03-27 At&T Corp. Method and apparatus for transferring money via a telephone call
JP2002536029A (ja) 1998-05-21 2002-10-29 ザ ガバメント オブ ザ ユナイテッドステイツ オブ アメリカ アズ リプレゼンテッド バイ ザ セクレタリー デパートメント オブ ヘルス アンド ヒューマン サービシーズ ザ ナショナル インステ 治療物質の圧力介在型選択的送達のための方法およびカニューレ
AU745302B2 (en) 1998-05-23 2002-03-21 Bieniarz, Andre Method of treatment for premature rupture of membranes in pregnancy (PROM)
US20020087184A1 (en) * 1998-06-18 2002-07-04 Eder Joseph C. Water-soluble coating for bioactive devices
DE69900689T2 (de) * 1998-06-26 2002-08-29 Quanam Medical Corp Topoisomerase inhibitoren zur restenose-prevention
US6369039B1 (en) * 1998-06-30 2002-04-09 Scimed Life Sytems, Inc. High efficiency local drug delivery
US6652581B1 (en) 1998-07-07 2003-11-25 Boston Scientific Scimed, Inc. Medical device with porous surface for controlled drug release and method of making the same
US6770473B1 (en) * 1998-08-21 2004-08-03 The Regents Of The University Of Michigan hKIS compositions and methods of use
US6186999B1 (en) * 1998-08-27 2001-02-13 The Cleveland Clinic Foundation Rigid clampable cannula
WO2000015285A1 (en) * 1998-09-14 2000-03-23 Mirus Corporation A process for delivering nucleic acids to cardiac tissue
US6299980B1 (en) 1998-09-29 2001-10-09 Medtronic Ave, Inc. One step lubricious coating
US6379691B1 (en) 1998-09-29 2002-04-30 Medtronic/Ave, Inc. Uses for medical devices having a lubricious, nitric oxide-releasing coating
US20040043068A1 (en) * 1998-09-29 2004-03-04 Eugene Tedeschi Uses for medical devices having a lubricious, nitric oxide-releasing coating
US6958147B1 (en) 1998-10-26 2005-10-25 Licentia Ltd Use of VEGF-C to prevent restenosis
US6361780B1 (en) 1998-11-12 2002-03-26 Cardiac Pacemakers, Inc. Microporous drug delivery system
US20030099682A1 (en) * 1998-11-20 2003-05-29 Francis Moussy Apparatus and method for control of tissue/implant interactions
DE19855521A1 (de) * 1998-12-02 2000-06-08 Tracoe Medizine Ges Fuer Tubus mit abgedichteter Manschette
US6309380B1 (en) * 1999-01-27 2001-10-30 Marian L. Larson Drug delivery via conformal film
US6398758B1 (en) 1999-02-16 2002-06-04 Stephen C. Jacobsen Medicament delivery system
US6200257B1 (en) 1999-03-24 2001-03-13 Proxima Therapeutics, Inc. Catheter with permeable hydrogel membrane
US6156373A (en) 1999-05-03 2000-12-05 Scimed Life Systems, Inc. Medical device coating methods and devices
DE60026513T2 (de) 1999-05-27 2006-10-05 Biocompatibles Uk Ltd., Farnham Lokale arzneistoffabgabe
US6398808B1 (en) 1999-06-15 2002-06-04 Scimed Life Systems, Inc. Localized delivery of genetic information from biostable materials
US6258121B1 (en) 1999-07-02 2001-07-10 Scimed Life Systems, Inc. Stent coating
US6770740B1 (en) 1999-07-13 2004-08-03 The Regents Of The University Of Michigan Crosslinked DNA condensate compositions and gene delivery methods
US6273901B1 (en) 1999-08-10 2001-08-14 Scimed Life Systems, Inc. Thrombosis filter having a surface treatment
US7850643B1 (en) * 1999-09-27 2010-12-14 Advanced Cardiovascular Systems, Inc. Drug diffusion barriers for a catheter assembly
US6682545B1 (en) * 1999-10-06 2004-01-27 The Penn State Research Foundation System and device for preventing restenosis in body vessels
US6738661B1 (en) 1999-10-22 2004-05-18 Biosynergetics, Inc. Apparatus and methods for the controllable modification of compound concentration in a tube
US6488671B1 (en) * 1999-10-22 2002-12-03 Corazon Technologies, Inc. Methods for enhancing fluid flow through an obstructed vascular site, and systems and kits for use in practicing the same
US6706034B1 (en) * 1999-12-30 2004-03-16 Advanced Cardiovascular Systems, Inc. Process for agent retention in biological tissues
US8172783B1 (en) 1999-12-30 2012-05-08 Advanced Cardiovascular Systems, Inc Conduit system for isolation of fluids in biological tissues
US7131959B2 (en) * 2003-01-23 2006-11-07 Integrated Vascular Interventional Technologies, L.C., (“IVIT LC”) Apparatus and methods for occluding an access tube anastomosed to sidewall of an anatomical vessel
US6595941B1 (en) * 2000-01-11 2003-07-22 Integrated Vascular Interventional Technologies, L.C. Methods for external treatment of blood
US6663590B2 (en) 2000-01-11 2003-12-16 Integrated Vascular Interventional Technologies, L.C. (Ivit, Lc) Vascular occlusal balloons and related vascular access devices and systems
US7118546B2 (en) * 2000-01-11 2006-10-10 Integrated Vascular Interventional Technologies, L.C. Apparatus and methods for facilitating repeated vascular access
US6656151B1 (en) 2000-01-11 2003-12-02 Integrated Vascular Interventional Technologies, L.C. (Ivit, Lc) Vascular access devices and systems
EP1250164B1 (de) * 2000-01-24 2005-11-23 Biocompatibles UK Limited Beschichtete implantate
CA2397377A1 (en) * 2000-01-25 2001-08-02 Edwards Lifesciences Corporation Bioactive coatings to prevent tissue overgrowth on artificial heart valves
DE60131146T2 (de) * 2000-02-25 2008-03-06 Ludwig Institute For Cancer Research Material und verfahren die hybridvaskularendothelwachstumfaktoren dns und proteine enthalten und screeningverfahren für modulatoren
US7373197B2 (en) 2000-03-03 2008-05-13 Intramedical Imaging, Llc Methods and devices to expand applications of intraoperative radiation probes
WO2001065911A2 (en) * 2000-03-03 2001-09-13 Valentis, Inc. Improved poloxamer and poloxamine compositions for nucleic acid delivery
US6602488B1 (en) * 2000-03-03 2003-08-05 Intramedical Imaging, Llc Use of radiopharmaceuticals and intraoperative radiation probe for delivery of medicinal treatments
CN100506293C (zh) * 2000-03-15 2009-07-01 祥丰医疗有限公司 促进内皮细胞粘附的涂层
US8088060B2 (en) 2000-03-15 2012-01-03 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
US9522217B2 (en) 2000-03-15 2016-12-20 Orbusneich Medical, Inc. Medical device with coating for capturing genetically-altered cells and methods for using same
US6629995B1 (en) * 2000-03-31 2003-10-07 Super Gen, Inc. Camptothecin conjugates
WO2001076514A2 (en) 2000-04-05 2001-10-18 Kyphon Inc. Methods and devices for treating fractured and/or diseased bone
US6682473B1 (en) * 2000-04-14 2004-01-27 Solace Therapeutics, Inc. Devices and methods for attenuation of pressure waves in the body
US7018645B1 (en) * 2000-04-27 2006-03-28 Macromed, Inc. Mixtures of various triblock polyester polyethylene glycol copolymers having improved gel properties
US6471968B1 (en) 2000-05-12 2002-10-29 Regents Of The University Of Michigan Multifunctional nanodevice platform
US6613025B1 (en) 2000-05-25 2003-09-02 Scimed Life Systems, Inc. Method and apparatus for diagnostic and therapeutic agent delivery
US6958075B2 (en) * 2001-09-18 2005-10-25 Celsion Corporation Device and method for treatment of tissue adjacent a bodily conduit by thermocompression
US7837720B2 (en) * 2000-06-20 2010-11-23 Boston Scientific Corporation Apparatus for treatment of tissue adjacent a bodily conduit with a gene or drug-coated compression balloon
US6660247B1 (en) * 2000-06-23 2003-12-09 Battelle Memorial Institute Multiple stimulus reversible hydrogels
WO2002000685A1 (en) * 2000-06-28 2002-01-03 University Of Pittsburgh Of The Commonwealth System Of Higher Education Localized delivery to a target surface
IL137090A (en) 2000-06-29 2010-04-15 Pentech Medical Devices Ltd Polymeric stent
US6685672B1 (en) 2000-07-13 2004-02-03 Edwards Lifesciences Corporation Multi-balloon drug delivery catheter for angiogenesis
US20050113798A1 (en) * 2000-07-21 2005-05-26 Slater Charles R. Methods and apparatus for treating the interior of a blood vessel
US20030120256A1 (en) * 2001-07-03 2003-06-26 Syntheon, Llc Methods and apparatus for sclerosing the wall of a varicose vein
US20050107738A1 (en) * 2000-07-21 2005-05-19 Slater Charles R. Occludable intravascular catheter for drug delivery and method of using the same
US7077836B2 (en) * 2000-07-21 2006-07-18 Vein Rx, Inc. Methods and apparatus for sclerosing the wall of a varicose vein
US20040018228A1 (en) * 2000-11-06 2004-01-29 Afmedica, Inc. Compositions and methods for reducing scar tissue formation
WO2002058578A1 (en) 2000-11-13 2002-08-01 Wit Ip Corporation Treatment catheters with thermally insulated regions
US6517888B1 (en) 2000-11-28 2003-02-11 Scimed Life Systems, Inc. Method for manufacturing a medical device having a coated portion by laser ablation
US6638246B1 (en) 2000-11-28 2003-10-28 Scimed Life Systems, Inc. Medical device for delivery of a biologically active material to a lumen
US6812217B2 (en) * 2000-12-04 2004-11-02 Medtronic, Inc. Medical device and methods of use
US6692458B2 (en) 2000-12-19 2004-02-17 Edwards Lifesciences Corporation Intra-pericardial drug delivery device with multiple balloons and method for angiogenesis
US6616626B2 (en) * 2000-12-21 2003-09-09 Scimed Life Systems, Inc. Infusion devices and method
US7481790B2 (en) * 2000-12-27 2009-01-27 Advanced Cardiovascular Systems, Inc. Vessel enlargement by arteriogenic factor delivery
US7763769B2 (en) 2001-02-16 2010-07-27 Kci Licensing, Inc. Biocompatible wound dressing
US7700819B2 (en) 2001-02-16 2010-04-20 Kci Licensing, Inc. Biocompatible wound dressing
US7238199B2 (en) * 2001-03-06 2007-07-03 The Board Of Regents Of The University Of Texas System Method and apparatus for stent deployment with enhanced delivery of bioactive agents
ES2328796T3 (es) 2001-03-14 2009-11-18 Myriad Genetics, Inc. Interaccion tsg101-gag y uso de la misma.
DE10115740A1 (de) 2001-03-26 2002-10-02 Ulrich Speck Zubereitung für die Restenoseprophylaxe
US20020161376A1 (en) 2001-04-27 2002-10-31 Barry James J. Method and system for delivery of coated implants
US6702744B2 (en) 2001-06-20 2004-03-09 Advanced Cardiovascular Systems, Inc. Agents that stimulate therapeutic angiogenesis and techniques and devices that enable their delivery
AU2002345328A1 (en) 2001-06-27 2003-03-03 Remon Medical Technologies Ltd. Method and device for electrochemical formation of therapeutic species in vivo
US20030083739A1 (en) * 2001-09-24 2003-05-01 Robert Cafferata Rational drug therapy device and methods
US6808518B2 (en) 2001-09-28 2004-10-26 Ethicon, Inc. Methods and devices for treating diseased blood vessels
DE60137593D1 (de) 2001-10-05 2009-03-19 Eugene A Larson Arzneimittelfreisetzung über gleichförmigen Film
WO2003030752A1 (en) * 2001-10-12 2003-04-17 Boston Scientific Limited Catheter with piezo elements for lesion diagnostics
US20040111108A1 (en) 2001-11-09 2004-06-10 Farnan Robert C. Balloon catheter with non-deployable stent
EP1441669B1 (de) 2001-11-09 2009-03-25 AngioScore, Inc. Ballonkatheter mit nicht ablegbarem stent
US6671562B2 (en) 2001-11-09 2003-12-30 Oscor Inc. High impedance drug eluting cardiac lead
US6783541B2 (en) * 2001-11-21 2004-08-31 Miravant Medical Technologies, Inc. Methods for inhibiting or suppressing stenosis of arteriovenous access fistulas and grafts
US8608661B1 (en) 2001-11-30 2013-12-17 Advanced Cardiovascular Systems, Inc. Method for intravascular delivery of a treatment agent beyond a blood vessel wall
US8062251B2 (en) * 2002-02-01 2011-11-22 Vascular Designs, Inc. Multi-function catheter and use thereof
US7645259B2 (en) * 2002-02-01 2010-01-12 Vascular Designs, Inc. Multi-function catheter and use thereof
US20050267407A1 (en) * 2002-02-01 2005-12-01 Vascular Designs, Inc. Multi-function catheter and use thereof
JP2005525848A (ja) 2002-02-13 2005-09-02 ベス イスラエル ディコネス メディカル センター 血管疾患の治療方法
MXPA04007897A (es) * 2002-02-15 2004-11-26 Celsion Corp Metodo y aparato para tratar el tejido adyacente a un conducto corporal con termocompresion y farmacos.
US20030181973A1 (en) * 2002-03-20 2003-09-25 Harvinder Sahota Reduced restenosis drug containing stents
US20030199917A1 (en) * 2002-04-22 2003-10-23 Knudson Mark B. Thrombus treatment with emboli management
US7939094B2 (en) * 2002-06-19 2011-05-10 Boston Scientific Scimed, Inc. Multiphase polymeric drug release region
US20030236513A1 (en) * 2002-06-19 2003-12-25 Scimed Life Systems, Inc. Implantable or insertable medical devices for controlled delivery of a therapeutic agent
US7105175B2 (en) * 2002-06-19 2006-09-12 Boston Scientific Scimed, Inc. Implantable or insertable medical devices for controlled delivery of a therapeutic agent
US8211455B2 (en) * 2002-06-19 2012-07-03 Boston Scientific Scimed, Inc. Implantable or insertable medical devices for controlled delivery of a therapeutic agent
US7361368B2 (en) 2002-06-28 2008-04-22 Advanced Cardiovascular Systems, Inc. Device and method for combining a treatment agent and a gel
DK1521603T3 (da) 2002-07-12 2011-04-18 Cook Inc Coated medicinsk anordning
DE10244847A1 (de) 2002-09-20 2004-04-01 Ulrich Prof. Dr. Speck Medizinische Vorrichtung zur Arzneimittelabgabe
US6802806B2 (en) 2002-09-23 2004-10-12 Cleveland Clinic Foundation Apparatus for use with an inflow cannula of ventricular assist device
US7060051B2 (en) * 2002-09-24 2006-06-13 Scimed Life Systems, Inc. Multi-balloon catheter with hydrogel coating
US7048714B2 (en) 2002-10-30 2006-05-23 Biorest Ltd. Drug eluting medical device with an expandable portion for drug release
US8524148B2 (en) * 2002-11-07 2013-09-03 Abbott Laboratories Method of integrating therapeutic agent into a bioerodible medical device
WO2004043300A1 (en) * 2002-11-07 2004-05-27 Abbott Laboratories Prosthesis with multiple drugs in discrete unmixed droplets
US8221495B2 (en) 2002-11-07 2012-07-17 Abbott Laboratories Integration of therapeutic agent into a bioerodible medical device
US7285287B2 (en) * 2002-11-14 2007-10-23 Synecor, Llc Carbon dioxide-assisted methods of providing biocompatible intraluminal prostheses
US6887266B2 (en) 2002-11-14 2005-05-03 Synecor, Llc Endoprostheses and methods of manufacture
US20040098090A1 (en) * 2002-11-14 2004-05-20 Williams Michael S. Polymeric endoprosthesis and method of manufacture
US20040098106A1 (en) * 2002-11-14 2004-05-20 Williams Michael S. Intraluminal prostheses and carbon dioxide-assisted methods of impregnating same with pharmacological agents
US9388427B2 (en) * 2002-12-02 2016-07-12 Biovec, Llc In vivo and ex vivo gene transfer into renal tissue using gutless adenovirus vectors
US7491234B2 (en) * 2002-12-03 2009-02-17 Boston Scientific Scimed, Inc. Medical devices for delivery of therapeutic agents
US20040111144A1 (en) * 2002-12-06 2004-06-10 Lawin Laurie R. Barriers for polymeric coatings
US6945957B2 (en) * 2002-12-30 2005-09-20 Scimed Life Systems, Inc. Valve treatment catheter and methods
US20040236415A1 (en) * 2003-01-02 2004-11-25 Richard Thomas Medical devices having drug releasing polymer reservoirs
US20060047261A1 (en) * 2004-06-28 2006-03-02 Shailendra Joshi Intra-arterial catheter for drug delivery
US8080026B2 (en) 2003-01-21 2011-12-20 Angioscore, Inc. Apparatus and methods for treating hardened vascular lesions
US7686824B2 (en) 2003-01-21 2010-03-30 Angioscore, Inc. Apparatus and methods for treating hardened vascular lesions
US7124570B2 (en) * 2003-01-23 2006-10-24 Integrated Vascular Interventional Technologies, L.C. Apparatus and methods for fluid occlusion of an access tube anastomosed to an anatomical vessel
US8313759B2 (en) * 2003-03-06 2012-11-20 Boston Scientific Scimed, Inc. Implantable or insertable medical devices containing miscible polymer blends for controlled delivery of a therapeutic agent
US6932930B2 (en) 2003-03-10 2005-08-23 Synecor, Llc Intraluminal prostheses having polymeric material with selectively modified crystallinity and methods of making same
US7318836B2 (en) * 2003-03-11 2008-01-15 Boston Scientific Scimed, Inc. Covered stent
US20040186549A1 (en) * 2003-03-19 2004-09-23 Swaminathan Jayaraman Braided stent with looped ends and method for making same
US20040243224A1 (en) * 2003-04-03 2004-12-02 Medtronic Vascular, Inc. Methods and compositions for inhibiting narrowing in mammalian vascular pathways
US7241455B2 (en) * 2003-04-08 2007-07-10 Boston Scientific Scimed, Inc. Implantable or insertable medical devices containing radiation-crosslinked polymer for controlled delivery of a therapeutic agent
US8821473B2 (en) 2003-04-15 2014-09-02 Abbott Cardiovascular Systems Inc. Methods and compositions to treat myocardial conditions
US8038991B1 (en) 2003-04-15 2011-10-18 Abbott Cardiovascular Systems Inc. High-viscosity hyaluronic acid compositions to treat myocardial conditions
US8383158B2 (en) * 2003-04-15 2013-02-26 Abbott Cardiovascular Systems Inc. Methods and compositions to treat myocardial conditions
CA2426115A1 (en) * 2003-04-18 2004-10-18 Victor Gurewich Methods, devices, and compositions for lysis of occlusive blood clots while sparing wound sealing clots
US7070958B2 (en) * 2003-04-18 2006-07-04 Thrombolytic Science, Inc. Methods of making pro-urokinase mutants
US7226473B2 (en) * 2003-05-23 2007-06-05 Brar Balbir S Treatment of stenotic regions
US20040236414A1 (en) * 2003-05-23 2004-11-25 Brar Balbir S. Devices and methods for treatment of stenotic regions
EP1633290B9 (de) * 2003-06-02 2009-09-02 Warsaw Orthopedic, Inc. Bandscheibenimplantate und methoden zu deren herstellung
US20090259236A2 (en) 2003-07-28 2009-10-15 Baronova, Inc. Gastric retaining devices and methods
US9498366B2 (en) * 2003-07-28 2016-11-22 Baronova, Inc. Devices and methods for pyloric anchoring
US9700450B2 (en) 2003-07-28 2017-07-11 Baronova, Inc. Devices and methods for gastrointestinal stimulation
US7357940B2 (en) * 2003-07-31 2008-04-15 Boston Scientific Scimed, Inc. Implantable or insertable medical devices containing graft copolymer for controlled delivery of therapeutic agents
US7914805B2 (en) * 2003-07-31 2011-03-29 Boston Scientific Scimed, Inc. Implantable or insertable medical devices containing radiation-treated polymer for improved delivery of therapeutic agent
US8870814B2 (en) * 2003-07-31 2014-10-28 Boston Scientific Scimed, Inc. Implantable or insertable medical devices containing silicone copolymer for controlled delivery of therapeutic agent
US9114199B2 (en) * 2003-07-31 2015-08-25 Boston Scientific Scimed, Inc. Implantable or insertable medical devices containing acrylic copolymer for controlled delivery of therapeutic agent
US20050033263A1 (en) * 2003-08-07 2005-02-10 Medtronic-Minimed, Inc. System and method for restenosis mitigation
WO2005023292A1 (en) 2003-09-03 2005-03-17 The General Hospital Corporation Methods of treating restenosis
US20050074453A1 (en) * 2003-10-02 2005-04-07 Ferree Bret A. Methods of preventing adhesions following laminectomies and other surgical procedures
AU2004289362A1 (en) * 2003-11-10 2005-05-26 Angiotech International Ag Intravascular devices and fibrosis-inducing agents
US7524275B2 (en) * 2003-11-14 2009-04-28 Cytyc Corporation Drug eluting brachytherapy methods and apparatus
JP2007512102A (ja) 2003-11-20 2007-05-17 ザ ヘンリー エム. ジャクソン ファウンデーション フォー ザ アドヴァンスメント オブ ミリタリー メディシン, インク. 流体の吸引のための携帯可能な手動ポンプ
US20050131513A1 (en) 2003-12-16 2005-06-16 Cook Incorporated Stent catheter with a permanently affixed conductor
US20050154451A1 (en) * 2003-12-18 2005-07-14 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US20050149174A1 (en) * 2003-12-18 2005-07-07 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US20050154455A1 (en) * 2003-12-18 2005-07-14 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US20050137683A1 (en) * 2003-12-19 2005-06-23 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US20050152942A1 (en) * 2003-12-23 2005-07-14 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US20050152940A1 (en) * 2003-12-23 2005-07-14 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US20050154452A1 (en) * 2003-12-23 2005-07-14 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US20050152943A1 (en) * 2003-12-23 2005-07-14 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
WO2005068020A1 (en) 2004-01-02 2005-07-28 Advanced Cardiovascular Systems, Inc. High-density lipoprotein coated medical devices
US20050159809A1 (en) * 2004-01-21 2005-07-21 Medtronic Vascular, Inc. Implantable medical devices for treating or preventing restenosis
US7803178B2 (en) 2004-01-30 2010-09-28 Trivascular, Inc. Inflatable porous implants and methods for drug delivery
US20050197691A1 (en) * 2004-02-18 2005-09-08 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US20050226991A1 (en) * 2004-04-07 2005-10-13 Hossainy Syed F Methods for modifying balloon of a catheter assembly
US20050228490A1 (en) * 2004-04-09 2005-10-13 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US7361168B2 (en) * 2004-04-21 2008-04-22 Acclarent, Inc. Implantable device and methods for delivering drugs and other substances to treat sinusitis and other disorders
US7654997B2 (en) * 2004-04-21 2010-02-02 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitus and other disorders of the ears, nose and/or throat
US9498563B2 (en) * 2004-04-23 2016-11-22 Boston Scientific Scimed, Inc. Medical articles having therapeutic-agent-containing regions formed from coalesced polymer particles
US7753876B2 (en) 2004-05-10 2010-07-13 Medtronic Vascular, Inc. Expandable jaw drug delivery catheter
US20050261762A1 (en) * 2004-05-21 2005-11-24 Medtronic Vascular, Inc. Medical devices to prevent or inhibit restenosis
US7824358B2 (en) * 2004-07-22 2010-11-02 Thoratec Corporation Heart pump connector
US8980300B2 (en) 2004-08-05 2015-03-17 Advanced Cardiovascular Systems, Inc. Plasticizers for coating compositions
US7758541B2 (en) * 2004-08-17 2010-07-20 Boston Scientific Scimed, Inc. Targeted drug delivery device and method
AU2005277797A1 (en) * 2004-08-19 2006-03-02 Vein Rx, Inc. An occludable intravascular catheter for drug delivery and method of using the same
WO2006033766A2 (en) * 2004-08-25 2006-03-30 The Regents Of The University Of Michigan Dendrimer based compositions and methods of using the same
US20060051390A1 (en) * 2004-09-03 2006-03-09 Schwarz Marlene C Medical devices having self-forming rate-controlling barrier for drug release
US20060062822A1 (en) * 2004-09-21 2006-03-23 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US8337475B2 (en) 2004-10-12 2012-12-25 C. R. Bard, Inc. Corporeal drainage system
US7402172B2 (en) * 2004-10-13 2008-07-22 Boston Scientific Scimed, Inc. Intraluminal therapeutic patch
US20060083770A1 (en) * 2004-10-15 2006-04-20 Specialty Coating Systems, Inc. Medical devices and methods of preparation and use
US20060085058A1 (en) * 2004-10-20 2006-04-20 Rosenthal Arthur L System and method for delivering a biologically active material to a body lumen
US20060088571A1 (en) * 2004-10-21 2006-04-27 Medtronic Vascular, Inc. Biocompatible and hemocompatible polymer compositions
MX2007006524A (es) * 2004-12-01 2007-06-22 Genzyme Corp Metodos para el suministro dirigido de material genetico al higado.
KR20060072734A (ko) * 2004-12-23 2006-06-28 두산인프라코어 주식회사 건설중장비의 압축공기 공급장치
US8828433B2 (en) 2005-04-19 2014-09-09 Advanced Cardiovascular Systems, Inc. Hydrogel bioscaffoldings and biomedical device coatings
US8303972B2 (en) 2005-04-19 2012-11-06 Advanced Cardiovascular Systems, Inc. Hydrogel bioscaffoldings and biomedical device coatings
US20080125745A1 (en) 2005-04-19 2008-05-29 Shubhayu Basu Methods and compositions for treating post-cardial infarction damage
US8187621B2 (en) 2005-04-19 2012-05-29 Advanced Cardiovascular Systems, Inc. Methods and compositions for treating post-myocardial infarction damage
US9539410B2 (en) 2005-04-19 2017-01-10 Abbott Cardiovascular Systems Inc. Methods and compositions for treating post-cardial infarction damage
US20060240253A1 (en) * 2005-04-22 2006-10-26 Cardiac Pacemakers, Inc. Guidewire and tube with lubricious coating
US20060241000A1 (en) * 2005-04-22 2006-10-26 Cardiac Pacemakers, Inc. Lubricious compound and medical device made of the same
US20060240060A1 (en) * 2005-04-22 2006-10-26 Cardiac Pacemakers, Inc. Lubricious compound and medical device made of the same
US20060240059A1 (en) * 2005-04-22 2006-10-26 Cardiac Pacemakers, Inc. Lubricious eluting polymer blend and coating made from the same
US8574259B2 (en) * 2005-05-10 2013-11-05 Lifescreen Sciences Llc Intravascular filter with drug reservoir
US10076641B2 (en) 2005-05-11 2018-09-18 The Spectranetics Corporation Methods and systems for delivering substances into luminal walls
WO2007011708A2 (en) 2005-07-15 2007-01-25 Micell Technologies, Inc. Stent with polymer coating containing amorphous rapamycin
PL1909973T3 (pl) 2005-07-15 2019-01-31 Micell Technologies, Inc. Polimerowe powłoki zawierające proszek leku o kontrolowanej morfologii
US20070027530A1 (en) * 2005-07-26 2007-02-01 Medtronic Vascular, Inc. Intraluminal device, catheter assembly, and method of use thereof
US9101949B2 (en) 2005-08-04 2015-08-11 Eilaz Babaev Ultrasonic atomization and/or seperation system
US20070041934A1 (en) * 2005-08-12 2007-02-22 Regents Of The University Of Michigan Dendrimer based compositions and methods of using the same
ES2363758T3 (es) 2005-08-15 2011-08-16 Vegenics Pty Ltd Vegf y pdgf modificados con propiedades angiogénicas mejoradas.
US7896539B2 (en) 2005-08-16 2011-03-01 Bacoustics, Llc Ultrasound apparatus and methods for mixing liquids and coating stents
US8444598B2 (en) * 2005-08-29 2013-05-21 Medtronic Vascular, Inc. Intravascular therapeutic agent delivery
US20070067020A1 (en) * 2005-09-22 2007-03-22 Medtronic Vasular, Inc. Intraluminal stent, delivery system, and a method of treating a vascular condition
WO2007038643A1 (en) 2005-09-26 2007-04-05 C.R. Bard, Inc. Catheter connection systems
US20070148390A1 (en) * 2005-12-27 2007-06-28 Specialty Coating Systems, Inc. Fluorinated coatings
US20080243068A1 (en) * 2005-12-29 2008-10-02 Kamal Ramzipoor Methods and apparatus for treatment of venous insufficiency
US8840660B2 (en) 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US20070173470A1 (en) * 2006-01-23 2007-07-26 Chi-Hung Lin Methods for delivering extracellular target into cells
US20090214496A1 (en) * 2006-01-30 2009-08-27 Licentia Ltd. Bmx/etk tyrosine kinase gene therapy materials and methods
US8089029B2 (en) 2006-02-01 2012-01-03 Boston Scientific Scimed, Inc. Bioabsorbable metal medical device and method of manufacture
US11278331B2 (en) 2006-02-07 2022-03-22 P Tech Llc Method and devices for intracorporeal bonding of implants with thermal energy
US8496657B2 (en) 2006-02-07 2013-07-30 P Tech, Llc. Methods for utilizing vibratory energy to weld, stake and/or remove implants
US7967820B2 (en) 2006-02-07 2011-06-28 P Tech, Llc. Methods and devices for trauma welding
US11253296B2 (en) 2006-02-07 2022-02-22 P Tech, Llc Methods and devices for intracorporeal bonding of implants with thermal energy
WO2007106554A2 (en) * 2006-03-14 2007-09-20 Progen Pharmaceuticals, Inc. Treatment and prevention of vascular hyperplasia using polyamine and polyamine analog compounds
US20070224235A1 (en) 2006-03-24 2007-09-27 Barron Tenney Medical devices having nanoporous coatings for controlled therapeutic agent delivery
US8187620B2 (en) 2006-03-27 2012-05-29 Boston Scientific Scimed, Inc. Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents
US8888684B2 (en) 2006-03-27 2014-11-18 Boston Scientific Scimed, Inc. Medical devices with local drug delivery capabilities
US20070231361A1 (en) * 2006-03-28 2007-10-04 Medtronic Vascular, Inc. Use of Fatty Acids to Inhibit the Growth of Aneurysms
US8048150B2 (en) 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
US8852625B2 (en) 2006-04-26 2014-10-07 Micell Technologies, Inc. Coatings containing multiple drugs
EP2035058A2 (de) * 2006-05-26 2009-03-18 MicroMuscle AB Vorrichtung und verfahren zur kontrollierten abgabe von chemischen substanzen
US11229746B2 (en) 2006-06-22 2022-01-25 Excelsior Medical Corporation Antiseptic cap
US8196584B2 (en) 2006-06-22 2012-06-12 Nellcor Puritan Bennett Llc Endotracheal cuff and technique for using the same
US8434487B2 (en) 2006-06-22 2013-05-07 Covidien Lp Endotracheal cuff and technique for using the same
US7837992B2 (en) 2006-06-22 2010-11-23 Beth Israel Deaconess Medical Center C-1 inhibitor prevents non-specific plasminogen activation by a prourokinase mutant without impeding fibrin-specific fibrinolysis
US9259535B2 (en) 2006-06-22 2016-02-16 Excelsior Medical Corporation Antiseptic cap equipped syringe
WO2007150069A2 (en) 2006-06-23 2007-12-27 Myriad Genetics, Inc. Dpyd gene variants and use thereof
US8815275B2 (en) 2006-06-28 2014-08-26 Boston Scientific Scimed, Inc. Coatings for medical devices comprising a therapeutic agent and a metallic material
JP2009542359A (ja) 2006-06-29 2009-12-03 ボストン サイエンティフィック リミテッド 選択的被覆部を備えた医療装置
EP2386322B1 (de) 2006-07-03 2017-12-27 Hemoteq AG Herstellung, Verfahren und Verwendung von wirkstofffreisetzenden Medizinprodukten zur permanenten Offenhaltung von Blutgefässen
WO2008079440A2 (en) 2006-07-10 2008-07-03 Medipacs, Inc. Super elastic epoxy hydrogel
US7732190B2 (en) * 2006-07-31 2010-06-08 Advanced Cardiovascular Systems, Inc. Modified two-component gelation systems, methods of use and methods of manufacture
JP2009545407A (ja) 2006-08-02 2009-12-24 ボストン サイエンティフィック サイムド,インコーポレイテッド 三次元分解制御を備えたエンドプロテーゼ
US9242005B1 (en) 2006-08-21 2016-01-26 Abbott Cardiovascular Systems Inc. Pro-healing agent formulation compositions, methods and treatments
US20080069855A1 (en) * 2006-08-21 2008-03-20 Bonutti Peter M Method of inhibiting the formation of adhesions and scar tissue and reducing blood loss
JP4602298B2 (ja) * 2006-08-31 2010-12-22 ホソカワミクロン株式会社 医薬製剤
US20080053454A1 (en) * 2006-09-01 2008-03-06 Nellcor Puritan Bennett Incorporated Endotracheal tube including a partially inverted cuff collar
JP2010503469A (ja) 2006-09-14 2010-02-04 ボストン サイエンティフィック リミテッド 薬物溶出性皮膜を有する医療デバイス
US8128689B2 (en) 2006-09-15 2012-03-06 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis with biostable inorganic layers
US8808726B2 (en) 2006-09-15 2014-08-19 Boston Scientific Scimed. Inc. Bioerodible endoprostheses and methods of making the same
WO2008034013A2 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Medical devices and methods of making the same
EP2068782B1 (de) 2006-09-15 2011-07-27 Boston Scientific Limited Biologisch erodierbare endoprothesen
JP2010503482A (ja) 2006-09-18 2010-02-04 ボストン サイエンティフィック リミテッド 内部人工器官
US8684175B2 (en) 2006-09-22 2014-04-01 Covidien Lp Method for shipping and protecting an endotracheal tube with an inflated cuff
US8561614B2 (en) 2006-09-28 2013-10-22 Covidien Lp Multi-layer cuffs for medical devices
US20080078401A1 (en) * 2006-09-29 2008-04-03 Nellcor Puritan Bennett Incorporated Self-sizing adjustable endotracheal tube
US8307830B2 (en) 2006-09-29 2012-11-13 Nellcor Puritan Bennett Llc Endotracheal cuff and technique for using the same
US20080078405A1 (en) 2006-09-29 2008-04-03 Crumback Gary L Self-sizing adjustable endotracheal tube
US7950393B2 (en) 2006-09-29 2011-05-31 Nellcor Puritan Bennett Llc Endotracheal cuff and technique for using the same
US20080078399A1 (en) 2006-09-29 2008-04-03 O'neil Michael P Self-sizing adjustable endotracheal tube
US8807136B2 (en) 2006-09-29 2014-08-19 Covidien Lp Self-sizing adjustable endotracheal tube
US8636767B2 (en) * 2006-10-02 2014-01-28 Micell Technologies, Inc. Surgical sutures having increased strength
WO2008051902A2 (en) * 2006-10-20 2008-05-02 Cpd, Llc Method of restoring the incretin effect
CN102886326A (zh) 2006-10-23 2013-01-23 米歇尔技术公司 用于在涂覆过程中为基底充电的保持器
US20110257723A1 (en) 2006-11-07 2011-10-20 Dc Devices, Inc. Devices and methods for coronary sinus pressure relief
US10624621B2 (en) 2006-11-07 2020-04-21 Corvia Medical, Inc. Devices and methods for the treatment of heart failure
US10413284B2 (en) 2006-11-07 2019-09-17 Corvia Medical, Inc. Atrial pressure regulation with control, sensing, monitoring and therapy delivery
US8745845B2 (en) 2006-11-07 2014-06-10 Dc Devices, Inc. Methods for mounting a prosthesis onto a delivery device
US8882697B2 (en) 2006-11-07 2014-11-11 Dc Devices, Inc. Apparatus and methods to create and maintain an intra-atrial pressure relief opening
US9232997B2 (en) 2006-11-07 2016-01-12 Corvia Medical, Inc. Devices and methods for retrievable intra-atrial implants
US7981150B2 (en) 2006-11-09 2011-07-19 Boston Scientific Scimed, Inc. Endoprosthesis with coatings
US9005672B2 (en) 2006-11-17 2015-04-14 Abbott Cardiovascular Systems Inc. Methods of modifying myocardial infarction expansion
US8741326B2 (en) 2006-11-17 2014-06-03 Abbott Cardiovascular Systems Inc. Modified two-component gelation systems, methods of use and methods of manufacture
US9737640B2 (en) 2006-11-20 2017-08-22 Lutonix, Inc. Drug releasing coatings for medical devices
US8430055B2 (en) 2008-08-29 2013-04-30 Lutonix, Inc. Methods and apparatuses for coating balloon catheters
US8998846B2 (en) 2006-11-20 2015-04-07 Lutonix, Inc. Drug releasing coatings for balloon catheters
US20080276935A1 (en) 2006-11-20 2008-11-13 Lixiao Wang Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs
US20080175887A1 (en) 2006-11-20 2008-07-24 Lixiao Wang Treatment of Asthma and Chronic Obstructive Pulmonary Disease With Anti-proliferate and Anti-inflammatory Drugs
US8414910B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
US8414526B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids
US9700704B2 (en) 2006-11-20 2017-07-11 Lutonix, Inc. Drug releasing coatings for balloon catheters
US8414525B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
US8425459B2 (en) 2006-11-20 2013-04-23 Lutonix, Inc. Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent
US8192760B2 (en) 2006-12-04 2012-06-05 Abbott Cardiovascular Systems Inc. Methods and compositions for treating tissue using silk proteins
US20080140002A1 (en) * 2006-12-06 2008-06-12 Kamal Ramzipoor System for delivery of biologically active substances with actuating three dimensional surface
WO2008083190A2 (en) 2006-12-28 2008-07-10 Boston Scientific Limited Bioerodible endoprostheses and methods of making same
US9737642B2 (en) 2007-01-08 2017-08-22 Micell Technologies, Inc. Stents having biodegradable layers
US11426494B2 (en) 2007-01-08 2022-08-30 MT Acquisition Holdings LLC Stents having biodegradable layers
DE112008000881A5 (de) 2007-01-21 2010-01-21 Hemoteq Ag Medizinprodukt zur Behandlung von Verschlüssen von Körperdurchgängen und zur Prävention drohender Wiederverschlüsse
US20080200873A1 (en) * 2007-02-16 2008-08-21 Alejandro Espinosa Methods and Apparatus for Infusing the Interior of a Blood Vessel
US8070797B2 (en) 2007-03-01 2011-12-06 Boston Scientific Scimed, Inc. Medical device with a porous surface for delivery of a therapeutic agent
US8431149B2 (en) 2007-03-01 2013-04-30 Boston Scientific Scimed, Inc. Coated medical devices for abluminal drug delivery
US20080210243A1 (en) * 2007-03-02 2008-09-04 Jessica Clayton Endotracheal cuff and technique for using the same
US8303639B2 (en) * 2007-03-22 2012-11-06 Medtronic Vascular, Inc. Releasable polymer on drug elution stent and method
US8067054B2 (en) 2007-04-05 2011-11-29 Boston Scientific Scimed, Inc. Stents with ceramic drug reservoir layer and methods of making and using the same
GR20070100224A (el) * 2007-04-13 2008-11-14 Κωνστατινος Σπαργιας Μπαλονι βαλβιδοπλαστικης για την στενωση αορτικησβαλβιδας που φερει επιστρωση εκλυομενης φαρμακευτικης ουσιας η οποια επιδρα προληπτικα κατα της επαναστενωσης.
AU2008275501A1 (en) * 2007-04-19 2009-01-15 The Regents Of The University Of Michigan Dendrimer based compositions and methods of using the same
US7976915B2 (en) 2007-05-23 2011-07-12 Boston Scientific Scimed, Inc. Endoprosthesis with select ceramic morphology
EP2170418B1 (de) * 2007-05-25 2016-03-16 Micell Technologies, Inc. Polymerfilme zur beschichtung von medizinprodukten
US20090004243A1 (en) 2007-06-29 2009-01-01 Pacetti Stephen D Biodegradable triblock copolymers for implantable devices
US9370642B2 (en) 2007-06-29 2016-06-21 J.W. Medical Systems Ltd. Adjustable-length drug delivery balloon
US9192697B2 (en) 2007-07-03 2015-11-24 Hemoteq Ag Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
US7942926B2 (en) 2007-07-11 2011-05-17 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8002823B2 (en) 2007-07-11 2011-08-23 Boston Scientific Scimed, Inc. Endoprosthesis coating
US7753285B2 (en) 2007-07-13 2010-07-13 Bacoustics, Llc Echoing ultrasound atomization and/or mixing system
US7780095B2 (en) 2007-07-13 2010-08-24 Bacoustics, Llc Ultrasound pumping apparatus
JP2010533563A (ja) 2007-07-19 2010-10-28 ボストン サイエンティフィック リミテッド 吸着抑制表面を有する内部人工器官
US8815273B2 (en) 2007-07-27 2014-08-26 Boston Scientific Scimed, Inc. Drug eluting medical devices having porous layers
US7931683B2 (en) 2007-07-27 2011-04-26 Boston Scientific Scimed, Inc. Articles having ceramic coated surfaces
WO2009018340A2 (en) 2007-07-31 2009-02-05 Boston Scientific Scimed, Inc. Medical device coating by laser cladding
JP2010535541A (ja) 2007-08-03 2010-11-25 ボストン サイエンティフィック リミテッド 広い表面積を有する医療器具用のコーティング
DE102007036685A1 (de) 2007-08-03 2009-02-05 Innora Gmbh Verbesserte arzneimittelbeschichtete Medizinprodukte deren Herstellung und Verwendung
US8333795B2 (en) * 2007-08-27 2012-12-18 Boston Scientific Scimed, Inc. Bulging balloon for bifurcation catheter assembly and methods
US20090069878A1 (en) * 2007-08-27 2009-03-12 Boston Scientific Scimed, Inc. Bifurcation post-dilatation balloon and methods
US20110137243A1 (en) * 2007-09-06 2011-06-09 Abbott Cardiovascular Systems Inc. Coating On A Balloon Device
US20110129514A1 (en) * 2007-09-06 2011-06-02 Hossainy Syed F A Hygroscopic coating on a balloon device
CA2698729C (en) 2007-09-07 2014-04-22 Baronova, Inc. Device for intermittently obstructing a gastric opening and method of use
US8568385B2 (en) * 2007-09-11 2013-10-29 Boston Scientific Scimed, Inc. Device and method for restricting blood flow to fibroids
US8052745B2 (en) 2007-09-13 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis
ES2626630T3 (es) 2007-10-30 2017-07-25 Uti Limited Partnership Procedimiento y sistema de liberación sostenida de agente esclerosante
US7938855B2 (en) 2007-11-02 2011-05-10 Boston Scientific Scimed, Inc. Deformable underlayer for stent
US8216632B2 (en) 2007-11-02 2012-07-10 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8029554B2 (en) 2007-11-02 2011-10-04 Boston Scientific Scimed, Inc. Stent with embedded material
WO2009061787A1 (en) * 2007-11-05 2009-05-14 Nanocopoeia, Inc. Coated devices and method of making coated devices that reduce smooth muscle cell proliferation and platelet activity
US8613721B2 (en) * 2007-11-14 2013-12-24 Medrad, Inc. Delivery and administration of compositions using interventional catheters
JP2011505520A (ja) 2007-12-03 2011-02-24 メディパックス インコーポレイテッド 流体計量供給装置
US8750978B2 (en) 2007-12-31 2014-06-10 Covidien Lp System and sensor for early detection of shock or perfusion failure and technique for using the same
US8157747B2 (en) 2008-02-15 2012-04-17 Lary Research & Development, Llc Single-use indicator for a surgical instrument and a surgical instrument incorporating same
WO2009111716A1 (en) * 2008-03-06 2009-09-11 Boston Scientific Scimed, Inc. Balloon catheter devices with sheath covering
WO2009151687A2 (en) 2008-03-12 2009-12-17 The Regents Of The University Of Michigan Dendrimer conjugates
KR20100132486A (ko) 2008-03-12 2010-12-17 안게스 엠지 인코포레이티드 약제 용출형 카테터 및 그 제조방법
MX2010010663A (es) * 2008-03-28 2010-11-09 Surmodics Inc Dispositivos medicos insertables que tienen substratos elasticos asociados con microparticulas, y metodos de suministro de farmacos.
CN101549150A (zh) * 2008-03-31 2009-10-07 刘建宁 尿激酶原及尿激酶原变体在急性心肌梗塞易化经皮冠状动脉介入中的应用
AU2009251504B2 (en) 2008-04-17 2013-09-05 Micell Technologies, Inc. Stents having bioabsorbable layers
WO2009131911A2 (en) 2008-04-22 2009-10-29 Boston Scientific Scimed, Inc. Medical devices having a coating of inorganic material
WO2009130265A2 (en) * 2008-04-23 2009-10-29 Andreas Grundlehner Medical device
WO2009132176A2 (en) 2008-04-24 2009-10-29 Boston Scientific Scimed, Inc. Medical devices having inorganic particle layers
US7998192B2 (en) 2008-05-09 2011-08-16 Boston Scientific Scimed, Inc. Endoprostheses
US8236046B2 (en) 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
EP2303350A2 (de) 2008-06-18 2011-04-06 Boston Scientific Scimed, Inc. Endoprothesen-beschichtung
US9510856B2 (en) 2008-07-17 2016-12-06 Micell Technologies, Inc. Drug delivery medical device
JP2011528275A (ja) 2008-07-17 2011-11-17 ミセル テクノロジーズ,インク. 薬物送達医療デバイス
US7985252B2 (en) 2008-07-30 2011-07-26 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US9295820B2 (en) 2008-08-14 2016-03-29 Surmodics, Inc. Method and apparatus for coating balloon catheters
EP2324864A4 (de) * 2008-09-08 2013-12-18 Nat Inst For Materials Science Verbundmaterial mit einer matrix von hohem molekulargewicht und einem verbundstoff von niedrigem molekulargewicht sowie verfahren zu seiner herstellung
US9198968B2 (en) 2008-09-15 2015-12-01 The Spectranetics Corporation Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
US8114429B2 (en) 2008-09-15 2012-02-14 Cv Ingenuity Corp. Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
US8128951B2 (en) 2008-09-15 2012-03-06 Cv Ingenuity Corp. Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
US8257722B2 (en) 2008-09-15 2012-09-04 Cv Ingenuity Corp. Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
US8500687B2 (en) 2008-09-25 2013-08-06 Abbott Cardiovascular Systems Inc. Stent delivery system having a fibrous matrix covering with improved stent retention
US8076529B2 (en) 2008-09-26 2011-12-13 Abbott Cardiovascular Systems, Inc. Expandable member formed of a fibrous matrix for intraluminal drug delivery
US8049061B2 (en) 2008-09-25 2011-11-01 Abbott Cardiovascular Systems, Inc. Expandable member formed of a fibrous matrix having hydrogel polymer for intraluminal drug delivery
US8226603B2 (en) 2008-09-25 2012-07-24 Abbott Cardiovascular Systems Inc. Expandable member having a covering formed of a fibrous matrix for intraluminal drug delivery
US8889635B2 (en) 2008-09-30 2014-11-18 The Regents Of The University Of Michigan Dendrimer conjugates
US8382824B2 (en) 2008-10-03 2013-02-26 Boston Scientific Scimed, Inc. Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides
DE102008042798A1 (de) * 2008-10-13 2010-04-15 Biotronik Vi Patent Ag Katheter mit einer Applikationsvorrichtung für flüssige Wirkstoffe
US8622996B2 (en) 2008-10-27 2014-01-07 Pursuit Vascular, Inc. Method for applying antimicrobial to proximal end of catheter
US9078992B2 (en) 2008-10-27 2015-07-14 Pursuit Vascular, Inc. Medical device for applying antimicrobial to proximal end of catheter
US9022984B2 (en) * 2008-10-27 2015-05-05 Pursuit Vascular, Inc. Apparatus for delivery of device and antimicrobial agent into trans-dermal catheter
US8622995B2 (en) 2009-10-26 2014-01-07 Pursuit Vascular, Inc. Method for delivery of antimicrobial to proximal end of catheter
WO2010054321A2 (en) 2008-11-07 2010-05-14 The Regents Of The University Of Michigan Methods of treating autoimmune disorders and/or inflammatory disorders
CN102271754B (zh) * 2008-11-10 2014-07-16 Med-El电气医疗器械有限公司 填充水凝胶的药物递送储器
US8540667B2 (en) * 2008-11-12 2013-09-24 Sanovas, Inc. Multi-balloon catheter for extravasated drug delivery
US8226601B2 (en) 2008-11-12 2012-07-24 Sanovas, Inc. Resector balloon system
WO2010064222A2 (en) 2008-12-01 2010-06-10 University College Cork, National University Of Ireland, Cork Igf1 for myocardial repair
US8231980B2 (en) 2008-12-03 2012-07-31 Boston Scientific Scimed, Inc. Medical implants including iridium oxide
US20100143325A1 (en) * 2008-12-09 2010-06-10 Vascular Laboratory, Inc. Composition And Methods Involving Thrombolytic Agents
US8834913B2 (en) 2008-12-26 2014-09-16 Battelle Memorial Institute Medical implants and methods of making medical implants
US8267992B2 (en) 2009-03-02 2012-09-18 Boston Scientific Scimed, Inc. Self-buffering medical implants
US8071156B2 (en) 2009-03-04 2011-12-06 Boston Scientific Scimed, Inc. Endoprostheses
EP2411083A4 (de) * 2009-03-23 2013-11-13 Micell Technologies Inc Medizinische wirkstofffreisetzungsvorrichtung
CN102481195B (zh) 2009-04-01 2015-03-25 米歇尔技术公司 涂覆支架
US8735506B2 (en) * 2009-04-03 2014-05-27 Ashland Licensing And Intellectual Property Llc Ultraviolet radiation curable pressure sensitive acrylic adhesive
EP2419058B1 (de) 2009-04-17 2018-02-28 Micell Technologies, Inc. Stents mit gesteuerter elution
EP2421571A2 (de) * 2009-04-24 2012-02-29 Boston Scientific Scimed, Inc. Verwendung von arzneimittelpolymorphen zur erzielung kontrollierter arzneifreisetzung aus einem beschichteten medizinprodukt
US8287937B2 (en) 2009-04-24 2012-10-16 Boston Scientific Scimed, Inc. Endoprosthese
US8551096B2 (en) * 2009-05-13 2013-10-08 Boston Scientific Scimed, Inc. Directional delivery of energy and bioactives
US20100292641A1 (en) * 2009-05-15 2010-11-18 Bandula Wijay Targeted drug delivery device and method
EP2253337A1 (de) * 2009-05-18 2010-11-24 Encapson B.V. Ballonkatheter mit druckempfindlichen Mikrokapseln
AU2010255329B2 (en) * 2009-06-02 2016-02-25 Concept Medical Inc. Non-implantable medical device coated with encapsulated nanoparticles containing therapeutic agents
US8590534B2 (en) 2009-06-22 2013-11-26 Covidien Lp Cuff for use with medical tubing and method and apparatus for making the same
US20110300205A1 (en) 2009-07-06 2011-12-08 Novartis Ag Self replicating rna molecules and uses thereof
ES2550634T3 (es) * 2009-07-10 2015-11-11 Boston Scientific Scimed, Inc. Uso de nanocristales para un balón de suministro de fármaco
ES2563730T3 (es) 2009-07-15 2016-03-16 Glaxosmithkline Biologicals S.A. Composiciones de proteína RSV F y procedimientos de fabricación de las mismas
US10080821B2 (en) 2009-07-17 2018-09-25 Boston Scientific Scimed, Inc. Nucleation of drug delivery balloons to provide improved crystal size and density
US20110022026A1 (en) * 2009-07-21 2011-01-27 Lake Region Manufacturing, Inc. d/b/a Lake Region Medical. Inc. Methods and Devices for Delivering Drugs Using Drug-Delivery or Drug-Coated Guidewires
JP5767226B2 (ja) * 2009-08-27 2015-08-19 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. 医療用デバイス
US9757107B2 (en) 2009-09-04 2017-09-12 Corvia Medical, Inc. Methods and devices for intra-atrial shunts having adjustable sizes
US9642993B2 (en) 2011-12-22 2017-05-09 Corvia Medical, Inc. Methods and devices for intra-atrial shunts having selectable flow rates
KR100982612B1 (ko) * 2009-09-09 2010-09-15 박효남 정밀 약액 주입량 조절장치
WO2011032011A1 (en) 2009-09-10 2011-03-17 Medipacs, Inc. Low profile actuator and improved method of caregiver controlled administration of therapeutics
US8945508B2 (en) 2009-10-13 2015-02-03 The Regents Of The University Of Michigan Dendrimer compositions and methods of synthesis
WO2011059586A2 (en) 2009-10-30 2011-05-19 The Regents Of The University Of Michigan Multifunctional small molecules
JP2013514278A (ja) 2009-12-18 2013-04-25 インターフェース バイオロジクス,インコーポレーテッド 自己集合コーティングからの薬物の局所送達
CA2785041A1 (en) 2010-01-29 2011-08-04 Dc Devices, Inc. Devices and methods for reducing venous pressure
US9500186B2 (en) 2010-02-01 2016-11-22 Medipacs, Inc. High surface area polymer actuator with gas mitigating components
EP2531140B1 (de) * 2010-02-02 2017-11-01 Micell Technologies, Inc. Stent und stenteinsatzsystem mit verbesserter einsetzbarkeit
WO2011097098A1 (en) * 2010-02-03 2011-08-11 Boston Scientific Scimed, Inc. A therapeutic balloon with systemic drug loss protection and controlled particle size release
US8038650B2 (en) * 2010-02-22 2011-10-18 Microsert Ltd. Slow release liquid drug delivery device
EP2361651B1 (de) * 2010-02-25 2016-04-27 Biotronik AG System aus einer Schutzhülse und einem medizinischen Gerät sowie Verfahren zur Herstellung desselben
WO2011119573A1 (en) 2010-03-23 2011-09-29 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
US8795762B2 (en) 2010-03-26 2014-08-05 Battelle Memorial Institute System and method for enhanced electrostatic deposition and surface coatings
EP2380604A1 (de) 2010-04-19 2011-10-26 InnoRa Gmbh Verbesserte Beschichtungsformulierung zum Einritzen oder Schneiden von Ballonkathetern
WO2011133655A1 (en) 2010-04-22 2011-10-27 Micell Technologies, Inc. Stents and other devices having extracellular matrix coating
US8389041B2 (en) 2010-06-17 2013-03-05 Abbott Cardiovascular Systems, Inc. Systems and methods for rotating and coating an implantable device
US8927000B2 (en) 2010-06-30 2015-01-06 Surmodics, Inc. Lipid coating for medical devices delivering bioactive agent
US9295663B2 (en) 2010-07-14 2016-03-29 Abbott Cardiovascular Systems Inc. Drug coated balloon with in-situ formed drug containing microspheres
CA2805631C (en) 2010-07-16 2018-07-31 Micell Technologies, Inc. Drug delivery medical device
EP2611476B1 (de) 2010-09-02 2016-08-10 Boston Scientific Scimed, Inc. Beschichtungsverfahren für wirkstofffreisetzungsballons mit wärmeinduziertem rewrap-gedächtnis
US8632559B2 (en) 2010-09-21 2014-01-21 Angioscore, Inc. Method and system for treating valve stenosis
US20120078227A1 (en) 2010-09-23 2012-03-29 Boston Scientific Scimed, Inc. Drug Coated Balloon Composition with High Drug Transfer to Vessel
AU2011316707A1 (en) 2010-10-11 2013-05-09 Novartis Ag Antigen delivery platforms
US8668675B2 (en) 2010-11-03 2014-03-11 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
DK2667892T3 (da) 2011-01-26 2019-05-13 Glaxosmithkline Biologicals Sa RSV-vaccineringsprogram
US8348890B2 (en) 2011-03-01 2013-01-08 Sanovas, Inc. Nested balloon catheter for localized drug delivery
US20160074581A1 (en) 2014-09-17 2016-03-17 Lawrence J. Gerrans Modulated Drug Delivery
US10898693B2 (en) 2011-03-01 2021-01-26 Sanovas Intellectual Property, Llc Nasal delivery of agents with nested balloon catheter
US8597239B2 (en) * 2011-03-01 2013-12-03 Sanovas, Inc. Abrading balloon catheter for extravasated drug delivery
US9415193B2 (en) 2011-03-04 2016-08-16 W. L. Gore & Associates, Inc. Eluting medical devices
US20120259401A1 (en) 2011-04-08 2012-10-11 Gerrans Lawrence J Balloon catheter for launching drug delivery device
US9180281B2 (en) 2011-04-08 2015-11-10 Sanovas, Inc. Adjustable balloon catheter for extravasated drug delivery
HUE034673T2 (en) 2011-05-13 2018-02-28 Glaxosmithkline Biologicals Sa Pre-fusion Rsv F antigens
US9937255B2 (en) 2011-05-18 2018-04-10 Nectero Medical, Inc. Coated balloons for blood vessel stabilization
US10464100B2 (en) 2011-05-31 2019-11-05 Micell Technologies, Inc. System and process for formation of a time-released, drug-eluting transferable coating
ES2656050T3 (es) 2011-07-06 2018-02-22 Glaxosmithkline Biologicals Sa Composiciones de combinación inmunogénica y usos de las mismas
CA2841047A1 (en) 2011-07-06 2013-01-10 Novartis Ag Immunogenic compositions and uses thereof
CN103796704B (zh) 2011-07-12 2016-12-07 博讯瓦勒公司 用于将抗微生物剂递送到经皮导管中的装置
US10117972B2 (en) * 2011-07-15 2018-11-06 Micell Technologies, Inc. Drug delivery medical device
WO2013022458A1 (en) 2011-08-05 2013-02-14 Boston Scientific Scimed, Inc. Methods of converting amorphous drug substance into crystalline form
US9056152B2 (en) 2011-08-25 2015-06-16 Boston Scientific Scimed, Inc. Medical device with crystalline drug coating
US20130190857A1 (en) * 2011-09-09 2013-07-25 Endoluminal Sciences Pty Ltd. Means for controlled sealing of endovascular devices
EP2578190A1 (de) * 2011-10-07 2013-04-10 Sanofi-Aventis Deutschland GmbH Intraokulare Injektionsvorrichtung
AU2012322704B2 (en) 2011-10-11 2017-09-07 Novartis Ag Recombinant self-replicating polycistronic RNA molecules
EP2766081A1 (de) 2011-10-11 2014-08-20 Boston Scientific Scimed, Inc. Wiederaufnahmehülle
US20140348863A1 (en) 2011-10-12 2014-11-27 Alessia Bianchi Cmv antigens and uses thereof
US10188772B2 (en) 2011-10-18 2019-01-29 Micell Technologies, Inc. Drug delivery medical device
CN104093445B (zh) * 2011-10-18 2016-09-07 米歇尔技术公司 药物递送医疗装置
WO2013085718A1 (en) 2011-12-08 2013-06-13 The Regents Of The University Of Michigan Multifunctional small molecules
WO2013091722A1 (en) 2011-12-23 2013-06-27 Innora Gmbh Drug-coated medical devices
DE102012001188A1 (de) * 2012-01-24 2013-07-25 Qualimed Innovative Medizinprodukte Gmbh Ballonkatheter
WO2013111341A1 (ja) * 2012-01-27 2013-08-01 有限会社日本エレクテル バルーンカテーテル
US9005155B2 (en) 2012-02-03 2015-04-14 Dc Devices, Inc. Devices and methods for treating heart failure
CN104245038B (zh) * 2012-03-09 2017-05-31 明讯科技有限公司 具有共同挤出的辐射不可透过部分的医疗球囊
JP2015510956A (ja) 2012-03-14 2015-04-13 メディパックス インコーポレイテッド 過剰反応性分子を含むスマートポリマー材料
US10588611B2 (en) 2012-04-19 2020-03-17 Corvia Medical Inc. Implant retention attachment and method of use
US9956385B2 (en) 2012-06-28 2018-05-01 The Spectranetics Corporation Post-processing of a medical device to control morphology and mechanical properties
US9649480B2 (en) 2012-07-06 2017-05-16 Corvia Medical, Inc. Devices and methods of treating or ameliorating diastolic heart failure through pulmonary valve intervention
JP2015522580A (ja) 2012-07-06 2015-08-06 ノバルティス アーゲー 免疫学的組成物およびその使用
US10173038B2 (en) 2012-09-05 2019-01-08 W. L. Gore & Associates, Inc. Retractable sheath devices, systems, and methods
CN104619375A (zh) * 2012-09-11 2015-05-13 波士顿科学西美德公司 用于与球囊导管一起使用的装载工具
US20140214002A1 (en) 2013-01-27 2014-07-31 Thermopeutix, Inc. Bifurcation catheter with variable length occlusion elements
US9775636B2 (en) 2013-03-12 2017-10-03 Corvia Medical, Inc. Devices, systems, and methods for treating heart failure
JP6330024B2 (ja) 2013-03-12 2018-05-23 マイセル・テクノロジーズ,インコーポレイテッド 生体吸収性バイオメディカルインプラント
ES2675373T3 (es) 2013-03-15 2018-07-10 Baronova, Inc. Dispositivo de obstrucción gástrica con bloqueo
CN105377318A (zh) 2013-05-15 2016-03-02 脉胜医疗技术公司 可生物吸收的生物医学植入物
US10117668B2 (en) 2013-10-08 2018-11-06 The Spectranetics Corporation Balloon catheter with non-deployable stent having improved stability
RU2635557C2 (ru) 2014-01-13 2017-11-14 Хафид БЕЛХАДЖ-ТАХАР Дендримерные композиции, способы их синтеза и их применение
US10525171B2 (en) 2014-01-24 2020-01-07 The Spectranetics Corporation Coatings for medical devices
US10675450B2 (en) 2014-03-12 2020-06-09 Corvia Medical, Inc. Devices and methods for treating heart failure
JP6787789B2 (ja) 2014-04-04 2020-11-18 プレジデント アンド フェローズ オブ ハーバード カレッジ 詰め替え可能な薬物送達デバイスおよびその使用方法
US9492594B2 (en) 2014-07-18 2016-11-15 M.A. Med Alliance SA Coating for intraluminal expandable catheter providing contact transfer of drug micro-reservoirs
US11406742B2 (en) 2014-07-18 2022-08-09 M.A. Med Alliance SA Coating for intraluminal expandable catheter providing contact transfer of drug micro-reservoirs
CA2955389C (en) 2014-07-23 2023-04-04 Corvia Medical, Inc. Devices and methods for treating heart failure
WO2016065245A1 (en) * 2014-10-24 2016-04-28 Incept, Llc Extra luminal scaffold
MA40871A (fr) 2014-10-29 2017-09-05 Novartis Ag Expression directe d'anticorps
ES2788697T3 (es) 2014-11-03 2020-10-22 Thrombolytic Science Llc Métodos y composiciones para trombólisis segura y eficaz
CN107405343A (zh) 2014-11-07 2017-11-28 明尼苏达大学董事会 可用于治疗疾病的盐和组合物
WO2016111899A1 (en) 2015-01-05 2016-07-14 Petrucci Gary M Methods and materials for treating lung disorders
CN117838375A (zh) * 2015-03-19 2024-04-09 南洋理工大学 支架组件和制备支架组件的方法
BR112017020491A2 (pt) 2015-03-25 2018-07-17 The Regents Of The University Of Michigan composições e métodos para distribuição de agentes de biomacromolécula.
WO2016182822A1 (en) 2015-05-08 2016-11-17 Icu Medical, Inc. Medical connectors configured to receive emitters of therapeutic agents
EP3305342A4 (de) * 2015-05-27 2019-02-06 Toray Industries, Inc. Antithrombotisches material
WO2017136557A1 (en) 2016-02-05 2017-08-10 Petrucci Gary M Methods and materials for treating nerve injuries and neurological disorders
WO2017158436A1 (en) 2016-03-17 2017-09-21 Oslo Universitetssykehus Hf Fusion proteins targeting tumour associated macrophages for treating cancer
US10702281B2 (en) 2016-07-18 2020-07-07 Merit Medical Systems, Inc. Inflatable radial artery compression device
JP7005609B2 (ja) 2016-10-14 2022-02-10 アイシーユー・メディカル・インコーポレーテッド 医療用コネクタのための浄化キャップ
KR20190073371A (ko) * 2016-10-20 2019-06-26 레트로배스큘러, 아이엔씨. 증대된 조성물 전달을 위한 방법 및 디바이스
WO2018104473A1 (en) 2016-12-07 2018-06-14 Oslo Universitetssykehus Hf Compositions and methods for cell therapy
JP6995869B2 (ja) 2017-02-23 2022-01-17 ボストン サイエンティフィック サイムド,インコーポレイテッド 医療装置と共に使用される搭載具
US10441300B2 (en) 2017-04-19 2019-10-15 Shockwave Medical, Inc. Drug delivery shock wave balloon catheter system
WO2018204206A2 (en) 2017-05-01 2018-11-08 Icu Medical, Inc. Medical fluid connectors and methods for providing additives in medical fluid lines
WO2018232305A1 (en) 2017-06-16 2018-12-20 Thrombolytic Science, Llc Methods and compositions for thrombolysis
US10478531B2 (en) 2017-06-22 2019-11-19 Gary M. Petrucci Methods and materials for treating blood vessels
WO2019195641A2 (en) 2018-04-06 2019-10-10 The Regents Of The University Of Michigan Inhibitors of rho/mrtf/srf-mediated gene transcription and methods for use of the same
EP3796948A4 (de) 2018-05-22 2022-03-02 Interface Biologics Inc. Zusammensetzungen und verfahren zur verabreichung von arzneimitteln an eine gefässwand
US11534595B2 (en) 2018-11-07 2022-12-27 Icu Medical, Inc. Device for delivering an antimicrobial composition into an infusion device
US11517732B2 (en) 2018-11-07 2022-12-06 Icu Medical, Inc. Syringe with antimicrobial properties
US10525250B1 (en) 2018-11-07 2020-01-07 Pursuit Vascular, Inc. Infusion device with antimicrobial properties
US11541220B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Needleless connector with antimicrobial properties
US11400195B2 (en) 2018-11-07 2022-08-02 Icu Medical, Inc. Peritoneal dialysis transfer set with antimicrobial properties
US11541221B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Tubing set with antimicrobial properties
AU2019384564B2 (en) 2018-11-21 2023-11-23 Icu Medical, Inc. Antimicrobial device comprising a cap with ring and insert
JP2024500319A (ja) 2020-12-07 2024-01-09 アイシーユー・メディカル・インコーポレーテッド 腹膜透析キャップ、システム、及び方法

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE380205C (de) * 1921-09-29 1924-01-19 Julius Frankenstein Dr Vorrichtung zur therapeutischen Behandlung von menschlichen Koerperhoehlen mit einem auf einem Luftzufuehrungsrohr luftdicht festsitzenden Gummimantel
DE1196327B (de) * 1963-04-06 1965-07-08 Willy Ruesch Fa Katheter
US3699956A (en) * 1970-10-01 1972-10-24 Tecna Corp Percutaneous lead device
CS173836B1 (de) * 1974-03-19 1977-03-31
JPS5950335B2 (ja) * 1976-07-06 1984-12-07 東洋紡績株式会社 抗血液凝固性医用軟質材料の製造法
JPS5435036A (en) * 1977-08-13 1979-03-14 Sumitomo Electric Industries Irrigation device
US4299226A (en) * 1979-08-08 1981-11-10 Banka Vidya S Coronary dilation method
US4481323A (en) * 1980-05-07 1984-11-06 Medical Research Associates, Ltd. #2 Hydrocarbon block copolymer with dispersed polysiloxane
US4364392A (en) * 1980-12-04 1982-12-21 Wisconsin Alumni Research Foundation Detachable balloon catheter
US4330497A (en) * 1981-01-19 1982-05-18 Sherwood Medical Industries Inc. Method of making grooved plastic medical tubing
US4448195A (en) * 1981-05-08 1984-05-15 Leveen Harry H Reinforced balloon catheter
CA1191064A (en) * 1981-12-31 1985-07-30 Bard (C. R.), Inc. Catheter with selectively rigidified portion
US4515593A (en) * 1981-12-31 1985-05-07 C. R. Bard, Inc. Medical tubing having exterior hydrophilic coating for microbiocide absorption therein and method for using same
US4417576A (en) 1982-02-25 1983-11-29 Baran Ostap E Double-wall surgical cuff
US4423725A (en) * 1982-03-31 1984-01-03 Baran Ostap E Multiple surgical cuff
US4636195A (en) 1982-04-02 1987-01-13 Harvey Wolinsky Method and apparatus for removing arterial constriction
US4769013A (en) * 1982-09-13 1988-09-06 Hydromer, Inc. Bio-effecting medical material and device
SU1069826A1 (ru) * 1982-09-17 1984-01-30 Запорожский медицинский институт Эндотрахеальна трубка
EP0121533B1 (de) * 1982-10-08 1990-02-28 HARDCASTLE, David Ballon-katheter und verfahren für dessen herstellung
US4603152A (en) * 1982-11-05 1986-07-29 Baxter Travenol Laboratories, Inc. Antimicrobial compositions
US4693243A (en) * 1983-01-14 1987-09-15 Buras Sharon Y Conduit system for directly administering topical anaesthesia to blocked laryngeal-tracheal areas
US4714460A (en) * 1983-07-29 1987-12-22 Reynaldo Calderon Methods and systems for retrograde perfusion in the body for curing it of the disease or immume deficiency
US4592340A (en) * 1984-05-02 1986-06-03 Boyles Paul W Artificial catheter means
US4589873A (en) * 1984-05-29 1986-05-20 Becton, Dickinson And Company Method of applying a hydrophilic coating to a polymeric substrate and articles prepared thereby
AU566085B2 (en) * 1984-06-04 1987-10-08 Terumo Kabushiki Kaisha Medical instrument with surface treatment
US4732930A (en) * 1985-05-20 1988-03-22 Massachusetts Institute Of Technology Reversible, discontinuous volume changes of ionized isopropylacrylamide cells
JPS62236560A (ja) * 1986-04-09 1987-10-16 テルモ株式会社 血管修復用カテ−テル
US4784647A (en) * 1986-07-30 1988-11-15 The Kendal Company Catheter meatal pad device
JPS6415056A (en) * 1987-07-09 1989-01-19 Hanarou Maeda Body indwelling tube
JPH01171571A (ja) * 1987-12-28 1989-07-06 Yoshiharu Yamawaki バルーンカテーテル
US4950256A (en) * 1988-04-07 1990-08-21 Luther Medical Products, Inc. Non-thrombogenic intravascular time release catheter
JP2683750B2 (ja) * 1988-06-06 1997-12-03 住友電気工業株式会社 カテーテル用バルーン
DE3821544C2 (de) * 1988-06-25 1994-04-28 H Prof Dr Med Just Dilatationskatheter
US4909258A (en) * 1988-08-08 1990-03-20 The Beth Israel Hospital Association Internal mammary artery (IMA) catheter
JP2836878B2 (ja) 1988-08-24 1998-12-14 スリピアン,マービン,ジェイ 生分解性高分子材料による管腔内封止
US5213580A (en) * 1988-08-24 1993-05-25 Endoluminal Therapeutics, Inc. Biodegradable polymeric endoluminal sealing process
CH676426A5 (de) * 1988-09-27 1991-01-31 Schneider Shiley Ag
US5091205A (en) * 1989-01-17 1992-02-25 Union Carbide Chemicals & Plastics Technology Corporation Hydrophilic lubricious coatings
US5021044A (en) * 1989-01-30 1991-06-04 Advanced Cardiovascular Systems, Inc. Catheter for even distribution of therapeutic fluids
US5087244A (en) 1989-01-31 1992-02-11 C. R. Bard, Inc. Catheter and method for locally applying medication to the wall of a blood vessel or other body lumen
US5328470A (en) * 1989-03-31 1994-07-12 The Regents Of The University Of Michigan Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor
US5047045A (en) * 1989-04-13 1991-09-10 Scimed Life Systems, Inc. Multi-section coaxial angioplasty catheter
US5041100A (en) * 1989-04-28 1991-08-20 Cordis Corporation Catheter and hydrophilic, friction-reducing coating thereon
US4994033A (en) * 1989-05-25 1991-02-19 Schneider (Usa) Inc. Intravascular drug delivery dilatation catheter
US5026607A (en) * 1989-06-23 1991-06-25 C. R. Bard, Inc. Medical apparatus having protective, lubricious coating
US4993412A (en) * 1989-08-02 1991-02-19 Eclipse Surgical Technologies, Inc. Method and apparatus for removal of obstructive substance from body channels
EP0497874A1 (de) * 1989-10-23 1992-08-12 Massachusetts Institute Of Technology Photoinduzierte reversible, diskontinuierliche volumenänderungen in gelen
US5843089A (en) * 1990-12-28 1998-12-01 Boston Scientific Corporation Stent lining
US5304121A (en) * 1990-12-28 1994-04-19 Boston Scientific Corporation Drug delivery system making use of a hydrogel polymer coating
US5674192A (en) * 1990-12-28 1997-10-07 Boston Scientific Corporation Drug delivery
US5439446A (en) * 1994-06-30 1995-08-08 Boston Scientific Corporation Stent and therapeutic delivery system
US5135516A (en) * 1989-12-15 1992-08-04 Boston Scientific Corporation Lubricious antithrombogenic catheters, guidewires and coatings
US5049132A (en) * 1990-01-08 1991-09-17 Cordis Corporation Balloon catheter for delivering therapeutic agents
ATE120377T1 (de) * 1990-02-08 1995-04-15 Howmedica Aufblasbarer dilatator.
US5120322A (en) * 1990-06-13 1992-06-09 Lathrotec, Inc. Method and apparatus for treatment of fibrotic lesions
US5180366A (en) * 1990-10-10 1993-01-19 Woods W T Apparatus and method for angioplasty and for preventing re-stenosis
DK0565604T3 (da) * 1990-12-28 2000-03-06 Boston Scient Corp System til afgivelse af lægemidler
WO1992011895A1 (en) * 1990-12-28 1992-07-23 Boston Scientific Corporation Balloon drug delivery system
US5324261A (en) * 1991-01-04 1994-06-28 Medtronic, Inc. Drug delivery balloon catheter with line of weakness
US5102402A (en) * 1991-01-04 1992-04-07 Medtronic, Inc. Releasable coatings on balloon catheters
WO1992013566A1 (en) * 1991-01-31 1992-08-20 Massachusetts Institute Of Technology Interpenetrating-polymer network phase-transition gels
US5171217A (en) * 1991-02-28 1992-12-15 Indiana University Foundation Method for delivery of smooth muscle cell inhibitors
US5213576A (en) * 1991-06-11 1993-05-25 Cordis Corporation Therapeutic porous balloon catheter
US5234457A (en) 1991-10-09 1993-08-10 Boston Scientific Corporation Impregnated stent
JPH06506019A (ja) * 1991-12-18 1994-07-07 シメッド ライフ システムズ インコーポレイテッド 潤滑性ポリマーネットワーク
US5336615A (en) * 1992-01-06 1994-08-09 Yale University Genetically engineered endothelial cells exhibiting enhanced migration and plasminogen activator activity
US5254089A (en) 1992-04-02 1993-10-19 Boston Scientific Corp. Medication dispensing balloon catheter
US5246437A (en) * 1992-04-10 1993-09-21 Abela George S Cell treatment apparatus and method
US5304120A (en) * 1992-07-01 1994-04-19 Btx Inc. Electroporation method and apparatus for insertion of drugs and genes into endothelial cells
US5336178A (en) * 1992-11-02 1994-08-09 Localmed, Inc. Intravascular catheter with infusion array

Also Published As

Publication number Publication date
CA2166101A1 (en) 1995-02-02
WO1995003083A1 (en) 1995-02-02
CA2166101C (en) 2005-10-04
EP0708671A4 (de) 1997-01-29
DE69429265T2 (de) 2002-08-22
US6409716B1 (en) 2002-06-25
EP0708671B1 (de) 2001-11-28
US5674192A (en) 1997-10-07
JPH09500561A (ja) 1997-01-21
US5954706A (en) 1999-09-21
EP0708671A1 (de) 1996-05-01

Similar Documents

Publication Publication Date Title
DE69429265T2 (de) Medizinabgabe
DE69424027D1 (de) Katheter
NO944047D0 (no) Strömningsledet kateter
FI935768A (fi) I fysiologisk omgivning upploesande mineralfibrer
DE69325089D1 (de) Chirurgischer endoklipp
FI956308A0 (fi) Injektioruisku
DE69413701T2 (de) Desinfektionsmittel
DE69423046T2 (de) Schnellzurückziehbarer katheter
FI931234A0 (fi) Foerfarande foer oevervakning av en patients tillstaond
BR9406092A (pt) Cateter
DE69307754D1 (de) Gewebe
FI92525B (fi) Ilmanvaihto-lämmitysyksikkö
FI955605A0 (fi) Aryloivia lääkkeitä
FI944137A (fi) Raakelilaite
DE9316984U1 (de) Zentralversorgungseinheit
DE9317847U1 (de) Kanüle
DE9314406U1 (de) Rollstuhl
DE69410327D1 (de) Rollstuhl
DE9310610U1 (de) Rollstuhl
KR950016714U (ko) 환자용 침대
KR950003044U (ko) 환자용 침대
DE9316220U1 (de) Katheter
DE9312616U1 (de) Rollstuhl
SE9301376D0 (sv) Patientanslutning
SE9301963D0 (sv) Patientanslutning

Legal Events

Date Code Title Description
8364 No opposition during term of opposition