DE69429852T2 - Vorrichtung und Verfahren zur Flüssigkeitstrennung - Google Patents

Vorrichtung und Verfahren zur Flüssigkeitstrennung

Info

Publication number
DE69429852T2
DE69429852T2 DE69429852T DE69429852T DE69429852T2 DE 69429852 T2 DE69429852 T2 DE 69429852T2 DE 69429852 T DE69429852 T DE 69429852T DE 69429852 T DE69429852 T DE 69429852T DE 69429852 T2 DE69429852 T2 DE 69429852T2
Authority
DE
Germany
Prior art keywords
phase
annular chamber
liquid sample
piston body
separation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69429852T
Other languages
English (en)
Other versions
DE69429852D1 (de
Inventor
Niels-Erik Holm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VIVOLUTION A/S, BIRKEROD, DK
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of DE69429852D1 publication Critical patent/DE69429852D1/de
Publication of DE69429852T2 publication Critical patent/DE69429852T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B1/00—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles
    • B04B1/04—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles with inserted separating walls
    • B04B1/06—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles with inserted separating walls of cylindrical shape
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021—Test tubes specially adapted for centrifugation purposes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B1/00—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles
    • B04B1/02—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles without inserted separating walls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B7/00—Elements of centrifuges
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0622—Valves, specific forms thereof distribution valves, valves having multiple inlets and/or outlets, e.g. metering valves, multi-way valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0485—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with a displaceable piston in the centrifuge chamber
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
DE69429852T 1993-11-19 1994-11-21 Vorrichtung und Verfahren zur Flüssigkeitstrennung Expired - Fee Related DE69429852T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15598493A 1993-11-19 1993-11-19

Publications (2)

Publication Number Publication Date
DE69429852D1 DE69429852D1 (de) 2002-03-21
DE69429852T2 true DE69429852T2 (de) 2002-08-22

Family

ID=22557593

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69429852T Expired - Fee Related DE69429852T2 (de) 1993-11-19 1994-11-21 Vorrichtung und Verfahren zur Flüssigkeitstrennung

Country Status (26)

Country Link
US (6) US5603845A (de)
EP (2) EP1152241A3 (de)
JP (1) JP3745397B2 (de)
KR (1) KR950013582A (de)
CN (1) CN1044977C (de)
AT (1) ATE213329T1 (de)
AU (1) AU688390B2 (de)
BR (1) BR9404484A (de)
CA (1) CA2136148C (de)
CZ (1) CZ280694A3 (de)
DE (1) DE69429852T2 (de)
DK (1) DK0654669T3 (de)
ES (1) ES2170763T3 (de)
FI (2) FI114340B (de)
HU (1) HU215246B (de)
IL (1) IL111524A (de)
MX (1) MXPA99004700A (de)
NO (1) NO314715B1 (de)
NZ (1) NZ264859A (de)
PL (1) PL176963B1 (de)
PT (1) PT654669E (de)
RU (1) RU2133468C1 (de)
SG (1) SG49212A1 (de)
SK (1) SK138394A3 (de)
UA (1) UA27898C2 (de)
ZA (1) ZA948564B (de)

Families Citing this family (148)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996006850A1 (en) * 1994-08-29 1996-03-07 Akzo Nobel N.V. Device for use in the isolation of a biological material such as nucleic acid
CZ164797A3 (cs) * 1994-12-02 1998-07-15 Bristol-Myers Sguibb Company Způsob oddělování fibrinu I z krevní plazmy a zařízení k tomu
US5830352A (en) 1994-12-02 1998-11-03 Bristol-Myers Squibb Company Centrifuge reagent delivery system
US5926387A (en) * 1995-06-30 1999-07-20 Beckman Instruments, Inc. Ultracentrifuge operation by computer system
USD420444S (en) 1995-12-07 2000-02-08 Bristol-Myers Squibb Company Blood processor
US6123655A (en) * 1996-04-24 2000-09-26 Fell; Claude Cell separation system with variable size chamber for the processing of biological fluids
US6132598A (en) * 1997-01-08 2000-10-17 Bristol-Myers Squibb Company Centrifuge apparatus with temperature control means
IL130729A0 (en) * 1997-01-08 2000-06-01 Bristol Myers Squibb Co Apparatus and methods for preparing blood or plasma component solutions of known concentration
WO1998030331A1 (en) * 1997-01-08 1998-07-16 Bristol-Myers Squibb Company Centrifuge apparatus for separating blood
NZ336398A (en) * 1997-01-08 2000-12-22 Bristol Myers Squibb Co A centrifuge apparatus with temperature control means
US6979307B2 (en) 1997-06-24 2005-12-27 Cascade Medical Enterprises Llc Systems and methods for preparing autologous fibrin glue
AU745761B2 (en) * 1997-07-25 2002-03-28 Vivolution A/S Blood product delivery system
US6846298B1 (en) 1997-07-25 2005-01-25 Bristol-Myers Squibb Company Blood product delivery system
ES2259286T3 (es) 1999-03-15 2006-10-01 Implant Innovations, Inc. Sistema de recogida de trombocitos.
US6393369B1 (en) * 1999-04-30 2002-05-21 Bristol-Myers Squibb Company System for control of blood processor
US6716187B1 (en) 1999-07-08 2004-04-06 Implant Innovations, Inc. Platelet concentration syringe kit
AU5918800A (en) * 1999-07-08 2001-01-30 Implant Innovations, Inc. Platelet concentration syringe kit
US6387263B1 (en) * 1999-09-02 2002-05-14 Bristol-Myers Squibb Company Apparatus and methods for preparing plasma solutions from blood with improved separation of plasma
US6524231B1 (en) * 1999-09-03 2003-02-25 Baxter International Inc. Blood separation chamber with constricted interior channel and recessed passage
US7033501B1 (en) * 1999-09-24 2006-04-25 Bristol-Myers Squibb Company Centrifuge apparatus and method with improved temperature control
US7045283B2 (en) * 2000-10-18 2006-05-16 The Regents Of The University Of California Methods of high-throughput screening for internalizing antibodies
US6610002B2 (en) 2001-04-09 2003-08-26 Medtronic, Inc. Method for handling blood sample to ensure blood components are isolated
JP2004536794A (ja) * 2001-04-09 2004-12-09 メドトロニック、インコーポレイテッド マイクロ遠心機を用いる血液成分の分離方法及びその使用法
US6605028B2 (en) 2001-04-09 2003-08-12 Medtronic, Inc. Blood centrifuge having integral heating to control cellular component temperature
US6790371B2 (en) 2001-04-09 2004-09-14 Medtronic, Inc. System and method for automated separation of blood components
US6579219B2 (en) * 2001-04-09 2003-06-17 Medtronic, Inc. Centrifuge bag and methods of use
US6612975B2 (en) 2001-04-09 2003-09-02 Medtronic, Inc. Blood centrifuge with an enhanced internal drive assembly
US6596181B2 (en) 2001-04-09 2003-07-22 Medtronic, Inc. Hard shell disposable reservoir having complex internal design for use in a centrifuge
US20020144939A1 (en) * 2001-04-09 2002-10-10 Dolecek Victor D. Miniaturized blood centrifuge having side mounted motor with belt drive
US6582350B2 (en) 2001-04-09 2003-06-24 Medtronic, Inc. Centrifuge container having curved linear shape
US6589155B2 (en) 2001-04-09 2003-07-08 Medtronic, Inc. Miniaturized blood centrifuge having side mounted motor with belt drive
US6835316B2 (en) 2001-04-09 2004-12-28 Medtronic, Inc. Clam shell blood reservoir holder with index line
US7011852B2 (en) * 2001-05-07 2006-03-14 Hemogenesis, Llc Separation of platelets from whole blood for use as a healant
US8101077B2 (en) * 2001-05-07 2012-01-24 Sivaprasad Sukavaneshvar Device for separating platelets from fluid suspensions
US6890291B2 (en) * 2001-06-25 2005-05-10 Mission Medical, Inc. Integrated automatic blood collection and processing unit
SE0102922D0 (sv) * 2001-08-31 2001-08-31 Astrazeneca Ab Method and apparatus for sample preparation
US6589153B2 (en) 2001-09-24 2003-07-08 Medtronic, Inc. Blood centrifuge with exterior mounted, self-balancing collection chambers
US7479123B2 (en) 2002-03-04 2009-01-20 Therakos, Inc. Method for collecting a desired blood component and performing a photopheresis treatment
US7211037B2 (en) * 2002-03-04 2007-05-01 Therakos, Inc. Apparatus for the continuous separation of biological fluids into components and method of using same
US6820506B2 (en) * 2002-03-27 2004-11-23 3M Innovative Properties Company Multi-chambered pump-valve device
EP1497645A2 (de) * 2002-04-19 2005-01-19 Mission Medical, Inc. Integrierte automatische blutverarbeitungseinheit
US7992725B2 (en) 2002-05-03 2011-08-09 Biomet Biologics, Llc Buoy suspension fractionation system
US7374678B2 (en) * 2002-05-24 2008-05-20 Biomet Biologics, Inc. Apparatus and method for separating and concentrating fluids containing multiple components
US20030205538A1 (en) * 2002-05-03 2003-11-06 Randel Dorian Methods and apparatus for isolating platelets from blood
US7832566B2 (en) 2002-05-24 2010-11-16 Biomet Biologics, Llc Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles
US20060278588A1 (en) 2002-05-24 2006-12-14 Woodell-May Jennifer E Apparatus and method for separating and concentrating fluids containing multiple components
AU2003249642A1 (en) * 2002-05-24 2003-12-12 Biomet Manufacturing Corp. Apparatus and method for separating and concentrating fluids containing multiple components
US7845499B2 (en) 2002-05-24 2010-12-07 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
WO2004050102A2 (en) * 2002-06-27 2004-06-17 Roberto Beretta Methods for preparing a solid-fibrin web
US7297272B2 (en) * 2002-10-24 2007-11-20 Fenwal, Inc. Separation apparatus and method
IL190642A (en) * 2002-11-13 2011-06-30 Biomet 3I Llc Dental implant system
WO2004103440A1 (ja) 2003-05-21 2004-12-02 Jms Co., Ltd. 血清調製用容器及びそれを用いた再生医療方法
JP4682591B2 (ja) * 2003-05-21 2011-05-11 株式会社ジェイ・エム・エス 血液成分分離収容装置及び血清調製方法
US20050054506A1 (en) * 2003-07-30 2005-03-10 Bradley Bruce J. Microbial concentration system
US20050049539A1 (en) * 2003-09-03 2005-03-03 O'hara Gerald P. Control system for driving fluids through an extracorporeal blood circuit
CN100417428C (zh) * 2003-09-30 2008-09-10 博奥生物有限公司 离心分离的仪器和方法
US20070161491A1 (en) * 2003-09-30 2007-07-12 Kabushiki Kaisha Kitazato Supply Centrifuging settling tube and organic cell collection tube
US7354515B2 (en) * 2004-02-23 2008-04-08 Millennium Medical Technologies, Inc. Fluid concentrator
US7588732B2 (en) * 2004-03-30 2009-09-15 Genesis Biosystems, Inc. Autologus tissue harvesting and irrigation device
JP4412029B2 (ja) * 2004-03-30 2010-02-10 パナソニック株式会社 密度勾配遠心分離による微生物抽出方法
JP4533706B2 (ja) * 2004-09-01 2010-09-01 旭化成株式会社 濾過方法及びそのシステム
WO2006029387A1 (en) * 2004-09-09 2006-03-16 Microfluidic Systems Inc. A handheld and portable microfluidic device to automatically prepare nucleic acids for analysis
US7476209B2 (en) * 2004-12-21 2009-01-13 Therakos, Inc. Method and apparatus for collecting a blood component and performing a photopheresis treatment
EP1848474B1 (de) 2005-02-07 2013-06-12 Hanuman LLC Vorrichtung und verfahren mit blutplättchenreichem plasmakonzentrat
ES2426941T3 (es) * 2005-02-07 2013-10-25 Hanuman Llc Aparato y procedimiento de concentrados de plasma rico en plaquetas
US7866485B2 (en) * 2005-02-07 2011-01-11 Hanuman, Llc Apparatus and method for preparing platelet rich plasma and concentrates thereof
DK1848473T3 (da) * 2005-02-07 2013-09-02 Hanuman Llc Plasmakoncentrationsanordning
US7789872B2 (en) 2005-03-23 2010-09-07 Shippert Ronald D Tissue transplantation method and apparatus
US8062286B2 (en) * 2005-03-23 2011-11-22 Shippert Ronald D Tissue transplantation method and apparatus
US8622997B2 (en) 2005-03-23 2014-01-07 Ronald D. Shippert Tissue transfer method and apparatus
US9581942B1 (en) 2005-03-23 2017-02-28 Shippert Enterprises, Llc Tissue transfer method and apparatus
US7794449B2 (en) 2005-03-23 2010-09-14 Shippert Ronald D Tissue transplantation method and apparatus
US7780649B2 (en) * 2005-03-23 2010-08-24 Shippert Ronald D Tissue transplantation method and apparatus
EP2323774B1 (de) * 2005-04-20 2019-08-21 SpineSmith Holdings, LLC Fluidkonzentrator
US7694828B2 (en) 2005-04-27 2010-04-13 Biomet Manufacturing Corp. Method and apparatus for producing autologous clotting components
FR2888585B1 (fr) * 2005-07-12 2007-09-14 Hemosystem Sa Dispositif de preparation d'un echantillon de fluide biologique en vue d'une analyse bacteriologique
US7618361B2 (en) * 2005-09-01 2009-11-17 Wagner Development, Inc. Gas driven solids discharge and pumping piston for a centrifugal separator
US8567609B2 (en) 2006-05-25 2013-10-29 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
KR100855621B1 (ko) 2006-06-26 2008-09-01 연세대학교 산학협력단 자가 트롬빈 및 피브리노겐의 제조장치 및 방법
NL1033365C2 (nl) 2007-02-09 2008-08-12 Medavinci Dev B V Inrichting en werkwijze voor scheiden en analyseren van bloed.
EP1967278A1 (de) * 2007-03-06 2008-09-10 Herbert Weidner Mehrstufige Zentrifuge mit Energie-Rückgewinnung zur Entsalzung von Meerwasser
US8328024B2 (en) 2007-04-12 2012-12-11 Hanuman, Llc Buoy suspension fractionation system
EP2146794B1 (de) 2007-04-12 2016-10-19 Biomet Biologics, LLC Fraktionierungssystem für suspensionen mit trennungsschwimmer
US20080302932A1 (en) * 2007-06-08 2008-12-11 Smiths Medical Asd, Inc. Mounting Clip for Fluid Reservoir
JP2010531142A (ja) * 2007-06-22 2010-09-24 サークル バイオロジクス、 エルエルシー． 液体濃縮装置、オートロガスな濃縮体液、およびそれらの使用方法
JP5163395B2 (ja) * 2007-09-26 2013-03-13 株式会社ジェイ・エム・エス 血液成分調製用容器及び血液成分分離収容装置
WO2009053927A2 (en) * 2007-10-23 2009-04-30 Lotus Bio (Nympheaa) Ltd. Biologic sample assay device
CN101821011B (zh) * 2007-10-24 2012-06-13 株式会社Jms 分离方法
EP3338896A1 (de) 2007-12-07 2018-06-27 Miltenyi Biotec GmbH Probenverarbeitungssysteme und -verfahren
CN101298008B (zh) * 2008-01-14 2012-10-03 经建中 应用于混合液体连续离心分离系统上的盘管结构
US8685258B2 (en) * 2008-02-27 2014-04-01 Fenwal, Inc. Systems and methods for conveying multiple blood components to a recipient
WO2009108890A1 (en) 2008-02-27 2009-09-03 Biomet Biologics, Llc Methods and compositions for delivering interleukin-1 receptor antagonist
US8075468B2 (en) * 2008-02-27 2011-12-13 Fenwal, Inc. Systems and methods for mid-processing calculation of blood composition
WO2009111338A1 (en) * 2008-02-29 2009-09-11 Biomet Manufacturing Corp. A system and process for separating a material
NL2001577C2 (nl) 2008-05-14 2009-11-17 Medavinci Dev B V Inrichting en werkwijze voor scheiden en analyseren van bloed.
US8177072B2 (en) * 2008-12-04 2012-05-15 Thermogenesis Corp. Apparatus and method for separating and isolating components of a biological fluid
US8187475B2 (en) * 2009-03-06 2012-05-29 Biomet Biologics, Llc Method and apparatus for producing autologous thrombin
US8313954B2 (en) 2009-04-03 2012-11-20 Biomet Biologics, Llc All-in-one means of separating blood components
WO2010119377A1 (en) * 2009-04-15 2010-10-21 Koninklijke Philips Electronics N.V. A gas-free fluid chamber
CN201404734Y (zh) * 2009-04-28 2010-02-17 厦门市毕恩生物技术有限公司 底部控制式标本过滤容器
WO2010127278A1 (en) 2009-05-01 2010-11-04 Trustees Of Boston University Disposal separator/concentrator device and method of use
US9011800B2 (en) * 2009-07-16 2015-04-21 Biomet Biologics, Llc Method and apparatus for separating biological materials
KR101069877B1 (ko) * 2009-10-28 2011-10-05 임기표 원심분리 키트 및 이를 이용한 원심분리 방법
US8591391B2 (en) 2010-04-12 2013-11-26 Biomet Biologics, Llc Method and apparatus for separating a material
WO2012021167A2 (en) * 2010-08-09 2012-02-16 Charles, Mirho Blood centrifuge with separation, sensor and dispense control system
US9555171B2 (en) 2010-09-30 2017-01-31 Depuy Mitek, Llc Methods and devices for collecting separate components of whole blood
US8469871B2 (en) 2010-11-19 2013-06-25 Kensey Nash Corporation Centrifuge
US8394006B2 (en) 2010-11-19 2013-03-12 Kensey Nash Corporation Centrifuge
US8556794B2 (en) 2010-11-19 2013-10-15 Kensey Nash Corporation Centrifuge
US8317672B2 (en) 2010-11-19 2012-11-27 Kensey Nash Corporation Centrifuge method and apparatus
US8870733B2 (en) 2010-11-19 2014-10-28 Kensey Nash Corporation Centrifuge
CN103370134B (zh) 2010-12-21 2015-12-16 通用电气医疗集团英国有限公司 过滤装置和方法
US9011684B2 (en) 2011-03-07 2015-04-21 Spinesmith Holdings, Llc Fluid concentrator with removable cartridge
US8887770B1 (en) 2011-03-17 2014-11-18 Ronald D. Shippert Vessel fill control method and apparatus
US9011846B2 (en) 2011-05-02 2015-04-21 Biomet Biologics, Llc Thrombin isolated from blood and blood fractions
US10201405B2 (en) 2011-06-28 2019-02-12 Biomet 3I, Llc System and method of dental implant and interface to abutment for restoration
CN103120865A (zh) * 2011-11-18 2013-05-29 博研国际有限公司 旋转容器、使用该旋转容器的流体过滤装置及系统
ES2602500T3 (es) 2011-11-25 2017-02-21 Miltenyi Biotec Gmbh Método de separación celular
WO2013096621A2 (en) * 2011-12-23 2013-06-27 The Broad Institute, Inc. Device and method for fragmenting polymers and particles
US9642956B2 (en) 2012-08-27 2017-05-09 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US9468709B2 (en) 2012-11-12 2016-10-18 Shippert Enterprises, Llc Syringe fill method and apparatus
US9895418B2 (en) 2013-03-15 2018-02-20 Biomet Biologics, Llc Treatment of peripheral vascular disease using protein solutions
US10208095B2 (en) 2013-03-15 2019-02-19 Biomet Manufacturing, Llc Methods for making cytokine compositions from tissues using non-centrifugal methods
US10143725B2 (en) 2013-03-15 2018-12-04 Biomet Biologics, Llc Treatment of pain using protein solutions
US9950035B2 (en) 2013-03-15 2018-04-24 Biomet Biologics, Llc Methods and non-immunogenic compositions for treating inflammatory disorders
US20140271589A1 (en) 2013-03-15 2014-09-18 Biomet Biologics, Llc Treatment of collagen defects using protein solutions
JP5896571B2 (ja) * 2013-10-15 2016-03-30 キム ホンＫｉｍ Ｈｏｎｇ 全血から高濃縮血漿を抽出する装置及び方法
KR102369602B1 (ko) 2014-01-31 2022-03-02 디에스엠 아이피 어셋츠 비.브이. 지방 조직 원심 분리기 및 그 사용 방법
US9550028B2 (en) 2014-05-06 2017-01-24 Biomet Biologics, LLC. Single step desiccating bead-in-syringe concentrating device
US10772997B2 (en) 2014-05-15 2020-09-15 Ronald D. Shippert Tissue parcelization method and apparatus
GB201416944D0 (en) * 2014-09-25 2014-11-12 Benson Viscometers Ltd An Apparatus for monitoring blood coagulation
US9713810B2 (en) 2015-03-30 2017-07-25 Biomet Biologics, Llc Cell washing plunger using centrifugal force
US9757721B2 (en) 2015-05-11 2017-09-12 Biomet Biologics, Llc Cell washing plunger using centrifugal force
US10413902B2 (en) 2015-07-17 2019-09-17 Stat-Diagnostica & Innovation, S.L. Apparatus for sample separation and collection
US10501715B1 (en) 2015-09-11 2019-12-10 Mark H. Widick System for the formation of fibrin foam
CA3013659C (en) 2016-03-10 2023-11-14 Arthrex, Inc. Systems and methods for preparing protein enhanced serums
AU2017230806B2 (en) 2016-03-10 2021-06-24 Arthrex, Inc. Systems and methods for preparing a thrombin serum
US10702629B2 (en) * 2016-05-13 2020-07-07 Black Tie Medical Inc. Conditioning harvested fat for re-injection
KR101926710B1 (ko) * 2016-07-19 2018-12-07 이준석 원심 분리용 용기, 및 원심 분리용 용기 내의 물질 이동 방법
CH713443A2 (de) * 2017-02-08 2018-08-15 Roth Felix Medizinalröhrchen.
EP3470142A1 (de) 2017-10-11 2019-04-17 Orthogen AG Vorrichtung mit einer ersten kammer zur aufnahme eines körperfluids
US11229722B2 (en) * 2018-01-29 2022-01-25 Omer Peled System and method for harvesting autologous adipose tissue
JP7007476B2 (ja) * 2018-05-31 2022-01-24 エッペンドルフ・ハイマック・テクノロジーズ株式会社 連続遠心機
KR101979382B1 (ko) * 2018-11-30 2019-05-17 (주)레보메드 줄기세포를 포함하는 체액세포 분리 및 농축키트
CN109593824B (zh) * 2019-01-04 2022-03-18 宁波艾捷康宁生物科技有限公司 一种游离核酸保存剂及采血保存装置
CN109750087A (zh) * 2019-03-05 2019-05-14 温州广立生物医药科技有限公司 一种血液cfDNA提取试剂盒
CN109731740B (zh) * 2019-03-08 2021-02-02 立讯精密工业（滁州）有限公司 一种灌胶装置及灌胶方法
CN111141569B (zh) * 2020-01-22 2020-12-29 兰州大学 一种积液类病理分析沉淀层提取装置

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1346485A (en) * 1918-05-13 1920-07-13 Arrigunaga Manuel De Device for the preparation of coffee or like beverages
US3064647A (en) * 1957-06-13 1962-11-20 Baxter Laboratories Inc Blood component separation method and apparatus
US3078847A (en) * 1959-05-06 1963-02-26 Baxter Laboratories Inc Blood handling method and apparatus
US3560163A (en) * 1968-12-23 1971-02-02 Armour Pharma Diagnostic device
US3799342A (en) * 1970-07-27 1974-03-26 Medical Res & Dev Inc Method of using a serum separator
US3911918A (en) * 1972-04-13 1975-10-14 Ralph D Turner Blood collection, storage and administering bag
US3846077A (en) * 1972-09-18 1974-11-05 P Ohringer Liquid sample collection tube
US3838809A (en) * 1973-04-16 1974-10-01 M Williams Automatic serum preparation station
US3932277A (en) * 1974-03-29 1976-01-13 Bio-Logics Products, Inc. Method and apparatus for separating blood fractions
FR2274918A1 (fr) * 1974-03-30 1976-01-09 Sarstedt Kunststoff Dispositif de filtrage pour la separation de fractions de sang
US4784715A (en) * 1975-07-09 1988-11-15 Milton Stoll Methods and apparatus for producing coherent or monolithic elements
DE2609089A1 (de) * 1976-03-05 1977-09-08 Heinz Kijewski Kaffeekanne mit siebeinsatz
DE2624373C2 (de) * 1976-05-31 1983-02-03 Arnold Dr. 8782 Karlstadt Seufert Verfahren zur Herstellung von steril filtriertem Kryopräzipilat mit einer Anreicherung des Faktors VIII
US4086924A (en) * 1976-10-06 1978-05-02 Haemonetics Corporation Plasmapheresis apparatus
US4300717A (en) * 1979-04-02 1981-11-17 Haemonetics Corporation Rotary centrifuge seal
AT366916B (de) * 1980-04-02 1982-05-25 Immuno Ag Vorrichtung zur applikation eines gewebeklebstoffes auf basis von menschlichen oder tierischenproteinen
US4334647A (en) * 1980-12-03 1982-06-15 Bird Machine Company, Inc. Centrifuges
DE3128611C2 (de) * 1981-07-20 1994-07-14 Hilti Ag Dosiergerät für Mehrkomponenten-Massen
US4735726A (en) * 1981-07-22 1988-04-05 E. I. Du Pont De Nemours And Company Plasmapheresis by reciprocatory pulsatile filtration
US4729829A (en) * 1981-07-22 1988-03-08 E. I. Du Pont De Nemours And Company Hollow fiber plasmapheresis module
US4668399A (en) * 1982-02-16 1987-05-26 E. I. Du Pont De Nemours And Company Hollow fiber plasmapheresis process
US4596657A (en) * 1982-06-04 1986-06-24 Miles Laboratories, Inc. Blood bag system with integral filtering means
DE3234250A1 (de) * 1982-09-15 1984-03-15 Hilti AG, 9494 Schaan Handgeraet zum abgeben von mehrkomponenten-massen
DE3305216C2 (de) * 1983-02-16 1986-04-10 Westfalia Separator Ag, 4740 Oelde Zentrifuge mit einer selbstentleerenden Schleudertrommel
US4530691A (en) * 1983-12-13 1985-07-23 Baxter Travenol Laboratories, Inc. Centrifuge with movable mandrel
CA1339745C (en) * 1984-04-10 1998-03-17 Martin Anderson Pesticidal benzoylurea compounds
ATE66392T1 (de) * 1985-09-16 1991-09-15 Mueller Drm Ag Klaer-filter-zentrifuge und verfahren zum trennen von suspensionen.
GB8602732D0 (en) * 1986-02-04 1986-03-12 Univ Brunel Taking samples from patients
US4666429A (en) * 1986-02-26 1987-05-19 Intelligent Medicine, Inc. Infusion device having improved valving apparatus
US4810378A (en) * 1986-04-21 1989-03-07 Miles Laboratories, Inc. Red blood cell filtering system
DK475386D0 (da) * 1986-10-03 1986-10-03 Weis Fogh Ulla Sivertsen Fremgangsmaade og apparat til fremstilling af biologiske stoffer
US4767396A (en) * 1987-03-03 1988-08-30 Haemonetics Corporation Method and apparatus for processing biological fluids
DE3706998A1 (de) * 1987-03-05 1988-09-15 Hettich Andreas Fa Zentrifugationskammer zur zytologischen untersuchung von zellsuspensionen
US4828716A (en) * 1987-04-03 1989-05-09 Andronic Devices, Ltd. Apparatus and method for separating phases of blood
US4795441A (en) * 1987-04-16 1989-01-03 Bhatt Kunjlata M Medication administration system
DE3723517A1 (de) * 1987-07-16 1989-01-26 Licentia Gmbh Handgefuehrtes, motorisch angetriebenes elektrowerkzeug
US4818386A (en) * 1987-10-08 1989-04-04 Becton, Dickinson And Company Device for separating the components of a liquid sample having higher and lower specific gravities
US4902281A (en) * 1988-08-16 1990-02-20 Corus Medical Corporation Fibrinogen dispensing kit
DE3920694A1 (de) * 1989-06-24 1991-01-10 Friedhelm Schneider Dosierpistole fuer zwei komponenten mit dynamischer mischkammer
CA2013021C (en) * 1989-11-29 1995-05-09 Richard Lewis Columbus Blood collection device
US5030215A (en) * 1990-01-03 1991-07-09 Cryolife, Inc. Preparation of fibrinogen/factor XIII precipitate
US5100372A (en) * 1990-03-02 1992-03-31 Haemonetics Corporation Core for blood processing apparatus
US5102407A (en) * 1990-03-13 1992-04-07 Miles Inc. Blood separation system
US5061381A (en) * 1990-06-04 1991-10-29 Abaxis, Inc. Apparatus and method for separating cells from biological fluids
US5137181A (en) * 1990-07-18 1992-08-11 Wilhelm A. Keller Manually operated appliance, in particular for a double dispensing cartridge for two-component substances
CN2089341U (zh) * 1990-10-24 1991-11-27 北京医科大学第一医院 血液回收机
IT1246530B (it) * 1991-03-29 1994-11-24 Miramed Spa Metodo e corredo pre-assemblato per l'ottenimento di colla di fibrina in ambiente completamente sterile.
CN1091315A (zh) * 1992-10-08 1994-08-31 E·R·斯奎布父子公司 血纤维蛋白封闭剂组合物及其使用方法

Also Published As

Publication number Publication date
ATE213329T1 (de) 2002-02-15
NO314715B1 (no) 2003-05-12
US6027655A (en) 2000-02-22
NZ264859A (en) 1996-10-28
CN1044977C (zh) 1999-09-08
NO944422L (no) 1995-05-22
IL111524A0 (en) 1995-01-24
NO944422D0 (no) 1994-11-18
DK0654669T3 (da) 2002-04-29
ZA948564B (en) 1995-07-26
EP0654669A3 (de) 1997-03-19
JPH07185393A (ja) 1995-07-25
PT654669E (pt) 2002-07-31
IL111524A (en) 1998-06-15
HUT70365A (en) 1995-10-30
CZ280694A3 (en) 1995-12-13
FI945401A0 (fi) 1994-11-16
US5776336A (en) 1998-07-07
EP0654669B1 (de) 2002-02-13
EP1152241A3 (de) 2004-12-01
JP3745397B2 (ja) 2006-02-15
ES2170763T3 (es) 2002-08-16
MXPA99004700A (es) 2004-08-31
RU94040895A (ru) 1996-09-20
AU7889794A (en) 1995-05-25
RU2133468C1 (ru) 1999-07-20
EP0654669A2 (de) 1995-05-24
HU9403324D0 (en) 1995-01-30
SK138394A3 (en) 1995-06-07
US5603845A (en) 1997-02-18
BR9404484A (pt) 1995-07-11
FI114340B (fi) 2004-09-30
SG49212A1 (en) 1998-05-18
FI945401A (fi) 1995-05-20
CN1108964A (zh) 1995-09-27
FI20040656A (fi) 2004-05-10
PL305907A1 (en) 1995-05-29
HU215246B (hu) 1998-11-30
US5792344A (en) 1998-08-11
PL176963B1 (pl) 1999-08-31
KR950013582A (ko) 1995-06-15
DE69429852D1 (de) 2002-03-21
CA2136148C (en) 2006-05-09
US5858253A (en) 1999-01-12
UA27898C2 (uk) 2000-10-16
CA2136148A1 (en) 1995-05-20
EP1152241A2 (de) 2001-11-07
US5741428A (en) 1998-04-21
AU688390B2 (en) 1998-03-12

Similar Documents

Publication Publication Date Title
ATE213329T1 (de) Vorrichtung und verfahren zur flüssigkeitstrennung
FI972339A (fi) Menetelmä ja laite fibriinin erottamiseksi veriplasmasta
DE69520375T2 (de) Zentrifuge mit ringfilter
FI943210A0 (fi) Laite ja menetelmä märkien hiukkasten erottamista varten
ATE237407T1 (de) Zentrifuge und verfahren zum betreiben der zentrifuge
DE50102530D1 (de) Verfahren zum Trennen eines Mehrphasengemisches und Dekantierzentrifungensystem zur Durchführung des Verfahrens
JPS57105207A (en) Method and apparatus for separating gas from high-viscosity liquid fluidized by gas agitation
SU1082492A1 (ru) Центрифуга дл разделени крови

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: VIVOLUTION A/S, BIRKEROD, DK

8339 Ceased/non-payment of the annual fee