DE69432300D1 - Biologische klebstoffzusammensetzung und verfahren zum fördern der haftung zwischen flächengewebe - Google Patents
Biologische klebstoffzusammensetzung und verfahren zum fördern der haftung zwischen flächengewebeInfo
- Publication number
- DE69432300D1 DE69432300D1 DE69432300T DE69432300T DE69432300D1 DE 69432300 D1 DE69432300 D1 DE 69432300D1 DE 69432300 T DE69432300 T DE 69432300T DE 69432300 T DE69432300 T DE 69432300T DE 69432300 D1 DE69432300 D1 DE 69432300D1
- Authority
- DE
- Germany
- Prior art keywords
- adhesive composition
- tissue
- biological adhesive
- liability
- promoting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/104—Aminoacyltransferases (2.3.2)
- C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
- A61L24/0015—Medicaments; Biocides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/10—Polypeptides; Proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/10—Polypeptides; Proteins
- A61L24/106—Fibrin; Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
- A61L2300/254—Enzymes, proenzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/834—Urine; urinary system
- Y10S530/835—Kidney
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/84—Bones; tendons; teeth; cartilage
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/841—Muscles; heart
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/842—Skin; hair; nails; sebaceous glands; cerumen
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/843—Digestive system
- Y10S530/846—Liver
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/85—Reproductive organs or embryos
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/071,528 US5549904A (en) | 1993-06-03 | 1993-06-03 | Biological adhesive composition and method of promoting adhesion between tissue surfaces |
US71528 | 1993-06-03 | ||
PCT/US1994/006208 WO1994028949A1 (en) | 1993-06-03 | 1994-06-03 | Biological adhesive composition and method of promoting adhesion between tissue surfaces |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69432300D1 true DE69432300D1 (de) | 2003-04-24 |
DE69432300T2 DE69432300T2 (de) | 2004-02-12 |
Family
ID=22101910
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69432300T Expired - Fee Related DE69432300T2 (de) | 1993-06-03 | 1994-06-03 | Biologische klebstoffzusammensetzung und verfahren zum fördern der haftung zwischen flächengewebe |
Country Status (10)
Country | Link |
---|---|
US (2) | US5549904A (de) |
EP (1) | EP0702572B1 (de) |
JP (1) | JP3483255B2 (de) |
AT (1) | ATE234643T1 (de) |
AU (2) | AU7051194A (de) |
CA (1) | CA2163250A1 (de) |
DE (1) | DE69432300T2 (de) |
ES (1) | ES2194869T3 (de) |
TW (1) | TW404836B (de) |
WO (1) | WO1994028949A1 (de) |
Families Citing this family (114)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5936035A (en) * | 1988-11-21 | 1999-08-10 | Cohesion Technologies, Inc. | Biocompatible adhesive compositions |
US6197325B1 (en) | 1990-11-27 | 2001-03-06 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
US6117425A (en) | 1990-11-27 | 2000-09-12 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, method of their production and use |
US6054122A (en) | 1990-11-27 | 2000-04-25 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
US7189410B1 (en) * | 1990-11-27 | 2007-03-13 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
JPH07328108A (ja) * | 1994-06-10 | 1995-12-19 | Ajinomoto Co Inc | 生体組織接着剤及び血液凝固剤 |
US6010871A (en) * | 1994-09-29 | 2000-01-04 | Ajinomoto Co., Inc. | Modification of peptide and protein |
US6833408B2 (en) | 1995-12-18 | 2004-12-21 | Cohesion Technologies, Inc. | Methods for tissue repair using adhesive materials |
JP4193917B2 (ja) | 1995-12-18 | 2008-12-10 | アンジオデバイス インターナショナル ゲーエムベーハー | 架橋ポリマー組成物およびその使用方法 |
US7883693B2 (en) | 1995-12-18 | 2011-02-08 | Angiodevice International Gmbh | Compositions and systems for forming crosslinked biomaterials and methods of preparation of use |
US6458889B1 (en) | 1995-12-18 | 2002-10-01 | Cohesion Technologies, Inc. | Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use |
AU8783798A (en) * | 1997-08-15 | 1999-03-08 | Children's Medical Center Corporation | Osteopontin coated surfaces and methods of use |
US6114119A (en) * | 1997-08-29 | 2000-09-05 | Wisconsin Alumni Research Foundation | Transglutaminase and gene encoding same |
US20030099620A1 (en) * | 1997-10-30 | 2003-05-29 | The General Hospital Corporation | Bonding of cartilaginous matrices using isolated chondrocytes |
JP2001521786A (ja) * | 1997-10-30 | 2001-11-13 | ザ ジュネラル ホスピタル コーポレーション | 単離軟骨細胞を使用した軟骨性基質の接着 |
US6190896B1 (en) | 1997-11-14 | 2001-02-20 | Bassam M. Fraij | Active human cellular transglutaminase |
EP1066051A4 (de) * | 1998-03-26 | 2002-05-02 | Gen Hospital Corp | Sciellin und seine verwendungen |
US20020022588A1 (en) * | 1998-06-23 | 2002-02-21 | James Wilkie | Methods and compositions for sealing tissue leaks |
US6190815B1 (en) * | 1998-08-11 | 2001-02-20 | Xerox Corporation | Toner compositions |
US7241730B2 (en) * | 1998-08-27 | 2007-07-10 | Universitat Zurich | Enzyme-mediated modification of fibrin for tissue engineering: fibrin formulations with peptides |
US6197061B1 (en) * | 1999-03-01 | 2001-03-06 | Koichi Masuda | In vitro production of transplantable cartilage tissue cohesive cartilage produced thereby, and method for the surgical repair of cartilage damage |
US6463335B1 (en) | 1999-10-04 | 2002-10-08 | Medtronic, Inc. | Temporary medical electrical lead having electrode mounting pad with biodegradable adhesive |
WO2001054748A1 (en) | 2000-01-25 | 2001-08-02 | Edwards Lifesciences Corporation | Delivery systems for treatment of restenosis and anastomotic intimal hyperplasia |
GB0011356D0 (en) | 2000-05-12 | 2000-06-28 | Univ Nottingham Trent | Medical implant materials |
US6685626B2 (en) | 2001-02-02 | 2004-02-03 | Regeneration Technologies, Inc. | Compositions, devices, methods, and kits for induction of adhesions |
US20060094112A1 (en) * | 2001-03-07 | 2006-05-04 | Omotunde Babalola | Biological scaffold |
JP2005523733A (ja) * | 2001-07-16 | 2005-08-11 | デピュイ・プロダクツ・インコーポレイテッド | 多孔質配給支持骨格材料および方法 |
US7618937B2 (en) * | 2001-07-20 | 2009-11-17 | Northwestern University | Peptidomimetic polymers for antifouling surfaces |
US8815793B2 (en) * | 2001-07-20 | 2014-08-26 | Northwestern University | Polymeric compositions and related methods of use |
US7858679B2 (en) * | 2001-07-20 | 2010-12-28 | Northwestern University | Polymeric compositions and related methods of use |
US7476257B2 (en) * | 2001-09-15 | 2009-01-13 | Rush University Medical Center | Methods to engineer stratified cartilage tissue |
US20030165473A1 (en) * | 2001-11-09 | 2003-09-04 | Rush-Presbyterian-St. Luke's Medical Center | Engineered intervertebral disc tissue |
ES2223227B1 (es) | 2002-05-31 | 2006-04-16 | Consejo Sup. Investig. Cientificas | Secuencia de nucleotidos de maiz codificante de una proteina con actividad transglutaminasa, y su uso. |
US8911831B2 (en) * | 2002-07-19 | 2014-12-16 | Northwestern University | Surface independent, surface-modifying, multifunctional coatings and applications thereof |
US20080171012A1 (en) * | 2007-01-11 | 2008-07-17 | Phillip Messersmith | Fouling Resistant Coatings and Methods of Making Same |
US7163545B2 (en) * | 2002-07-29 | 2007-01-16 | Mayo Foundation For Medical Education And Research | Spinal cord surgical implant |
WO2004042068A2 (en) * | 2002-10-31 | 2004-05-21 | Northwestern University | Injectable and bioadhesive polymeric hydrogels as well as related methods of enzymatic preparation |
WO2004060405A2 (en) * | 2002-12-30 | 2004-07-22 | Angiotech International Ag | Tissue reactive compounds and compositions and uses thereof |
JP2006516548A (ja) * | 2002-12-30 | 2006-07-06 | アンジオテック インターナショナル アクツィエン ゲゼルシャフト | 迅速ゲル化ポリマー組成物からの薬物送達法 |
JP2004283371A (ja) * | 2003-03-20 | 2004-10-14 | Nagoya Industrial Science Research Inst | 医用材料 |
US7067123B2 (en) | 2003-04-29 | 2006-06-27 | Musculoskeletal Transplant Foundation | Glue for cartilage repair |
US7901457B2 (en) | 2003-05-16 | 2011-03-08 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
CA2545874C (en) | 2003-10-06 | 2012-02-21 | 3F Therapeutics, Inc. | Minimally invasive valve replacement system |
US20050075730A1 (en) | 2003-10-06 | 2005-04-07 | Myers Keith E. | Minimally invasive valve replacement system |
ES2396689T3 (es) | 2003-12-11 | 2013-02-25 | Isto Technologies Inc. | Sistema de cartílago particulado |
BRPI0510477B1 (pt) | 2004-04-28 | 2023-01-17 | Angiotech Biomaterials Corporation | Método para formar um gel e dispositivo para uso em aplicações médicas |
US7670282B2 (en) | 2004-06-14 | 2010-03-02 | Pneumrx, Inc. | Lung access device |
US7608579B2 (en) * | 2004-06-16 | 2009-10-27 | Pneumrx, Inc. | Lung volume reduction using glue compositions |
US20050281798A1 (en) * | 2004-06-16 | 2005-12-22 | Glen Gong | Targeting sites of damaged lung tissue using composition |
US20050281739A1 (en) * | 2004-06-16 | 2005-12-22 | Glen Gong | Imaging damaged lung tissue using compositions |
US20050281740A1 (en) * | 2004-06-16 | 2005-12-22 | Glen Gong | Imaging damaged lung tissue |
WO2006009688A2 (en) * | 2004-06-16 | 2006-01-26 | Pneumrx, Inc. | Intra-bronchial lung volume reduction system |
US20050281799A1 (en) * | 2004-06-16 | 2005-12-22 | Glen Gong | Targeting damaged lung tissue using compositions |
US7678767B2 (en) | 2004-06-16 | 2010-03-16 | Pneumrx, Inc. | Glue compositions for lung volume reduction |
US7553810B2 (en) * | 2004-06-16 | 2009-06-30 | Pneumrx, Inc. | Lung volume reduction using glue composition |
US20050288796A1 (en) * | 2004-06-23 | 2005-12-29 | Hani Awad | Native soft tissue matrix for therapeutic applications |
US7766891B2 (en) | 2004-07-08 | 2010-08-03 | Pneumrx, Inc. | Lung device with sealing features |
US7766938B2 (en) | 2004-07-08 | 2010-08-03 | Pneumrx, Inc. | Pleural effusion treatment device, method and material |
US8303973B2 (en) | 2004-09-17 | 2012-11-06 | Angiotech Pharmaceuticals (Us), Inc. | Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use |
US7837740B2 (en) | 2007-01-24 | 2010-11-23 | Musculoskeletal Transplant Foundation | Two piece cancellous construct for cartilage repair |
US20060111778A1 (en) * | 2004-10-29 | 2006-05-25 | Michalow Alexander E | Methods of promoting healing of cartilage defects and method of causing stem cells to differentiate by the articular chondrocyte pathway |
JP4874259B2 (ja) | 2004-11-23 | 2012-02-15 | ヌームアールエックス・インコーポレーテッド | 標的部位にアクセスするための操縦可能な装置 |
US7815926B2 (en) * | 2005-07-11 | 2010-10-19 | Musculoskeletal Transplant Foundation | Implant for articular cartilage repair |
US8480757B2 (en) | 2005-08-26 | 2013-07-09 | Zimmer, Inc. | Implants and methods for repair, replacement and treatment of disease |
US8921109B2 (en) | 2005-09-19 | 2014-12-30 | Histogenics Corporation | Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof |
US7732539B2 (en) * | 2006-02-16 | 2010-06-08 | National Science Foundation | Modified acrylic block copolymers for hydrogels and pressure sensitive wet adhesives |
US9402633B2 (en) | 2006-03-13 | 2016-08-02 | Pneumrx, Inc. | Torque alleviating intra-airway lung volume reduction compressive implant structures |
US8157837B2 (en) | 2006-03-13 | 2012-04-17 | Pneumrx, Inc. | Minimally invasive lung volume reduction device and method |
US8888800B2 (en) | 2006-03-13 | 2014-11-18 | Pneumrx, Inc. | Lung volume reduction devices, methods, and systems |
EP2029184B1 (de) | 2006-05-26 | 2011-02-23 | Baxter International Inc. | Injizierbare fibrin-zusammensetzung zur knochenverstärkung |
CA2651820C (en) * | 2006-05-26 | 2015-01-13 | Baxter International Inc. | Injectable bone void filler |
DE102006033167A1 (de) | 2006-07-10 | 2008-01-24 | Gelita Ag | Verwendung von Gelatine und einem Vernetzungsmittel zur Herstellung eines vernetzenden medizinischen Klebers |
DE102006033168A1 (de) | 2006-07-10 | 2008-01-17 | Gelita Ag | Verwendung von Gelatine und einem Vernetzungsmittel zur Herstellung einer vernetzenden therapeutischen Zusammensetzung |
US8563117B2 (en) * | 2006-08-04 | 2013-10-22 | Phillip B. Messersmith | Biomimetic modular adhesive complex: materials, methods and applications therefore |
JP5597836B2 (ja) | 2006-08-04 | 2014-10-01 | ケンジー ナッシュ コーポレイション | バイオミメティック化合物およびその合成方法 |
WO2008036763A2 (en) * | 2006-09-20 | 2008-03-27 | Pneumrx, Inc. | Tissue adhesive compositions and methods thereof |
DK176786B1 (da) * | 2006-12-08 | 2009-08-24 | Dat Schaub A M B A | A process for joining of pieces of natural casing |
US7935363B2 (en) | 2006-12-12 | 2011-05-03 | Synthasome, Inc. | Composite material for tissue repair |
WO2008076407A2 (en) | 2006-12-15 | 2008-06-26 | Lifebond Ltd. | Gelatin-transglutaminase hemostatic dressings and sealants |
US8133484B2 (en) | 2006-12-15 | 2012-03-13 | Lifebond Ltd | Hemostatic materials and dressing |
US20080154233A1 (en) * | 2006-12-20 | 2008-06-26 | Zimmer Orthobiologics, Inc. | Apparatus for delivering a biocompatible material to a surgical site and method of using same |
US8163549B2 (en) | 2006-12-20 | 2012-04-24 | Zimmer Orthobiologics, Inc. | Method of obtaining viable small tissue particles and use for tissue repair |
US8673286B2 (en) | 2007-04-09 | 2014-03-18 | Northwestern University | DOPA-functionalized, branched, poly(aklylene oxide) adhesives |
US8383092B2 (en) * | 2007-02-16 | 2013-02-26 | Knc Ner Acquisition Sub, Inc. | Bioadhesive constructs |
US10278947B2 (en) | 2007-02-28 | 2019-05-07 | Orthopeutics, L.P. | Crosslinker enhanced repair of connective tissues |
US8435551B2 (en) | 2007-03-06 | 2013-05-07 | Musculoskeletal Transplant Foundation | Cancellous construct with support ring for repair of osteochondral defects |
WO2008128075A1 (en) | 2007-04-12 | 2008-10-23 | Isto Technologies, Inc. | Compositions and methods for tissue repair |
CN101668549B (zh) * | 2007-04-23 | 2014-04-09 | 巴克斯特国际公司 | 包含锶化合物的纤维蛋白组合物 |
WO2009111069A1 (en) | 2008-03-05 | 2009-09-11 | Musculoskeletal Transplant Foundation | Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles |
WO2009153748A2 (en) * | 2008-06-18 | 2009-12-23 | Lifebond Ltd | Methods and devices for use with sealants |
CN104031393B (zh) | 2008-06-18 | 2017-08-01 | 生命连结有限公司 | 改进的交联组合物 |
WO2009153751A2 (en) * | 2008-06-18 | 2009-12-23 | Lifebond Ltd | A method for enzymatic cross-linking of a protein |
US8632605B2 (en) | 2008-09-12 | 2014-01-21 | Pneumrx, Inc. | Elongated lung volume reduction devices, methods, and systems |
WO2010083051A2 (en) * | 2009-01-15 | 2010-07-22 | ProChon Biotech, Ltd. | Cartilage particle tissue mixtures optionally combined with a cancellous construct |
JP5809621B2 (ja) | 2009-05-18 | 2015-11-11 | ヌームアールエックス・インコーポレーテッド | 患者の肺を治療するインプラント |
US9597430B2 (en) * | 2009-07-31 | 2017-03-21 | Synthasome, Inc. | Synthetic structure for soft tissue repair |
US20110130465A1 (en) * | 2009-12-01 | 2011-06-02 | Nerites Corporation | Coatings for prevention of biofilms |
CA2782863A1 (en) | 2009-12-22 | 2011-06-30 | Lifebond Ltd | Modification of enzymatic crosslinkers for controlling properties of crosslinked matrices |
US9163212B2 (en) | 2010-01-25 | 2015-10-20 | Warsaw Orthopedic, Inc. | Osteogenic cell delivery matrix |
ES2567174T3 (es) | 2010-08-05 | 2016-04-20 | Lifebond Ltd | Composición seca en apósitos y adhesivos para heridas |
US9549760B2 (en) | 2010-10-29 | 2017-01-24 | Kyphon Sarl | Reduced extravasation of bone cement |
EP2637707A4 (de) | 2010-11-09 | 2014-10-01 | Kensey Nash Corp | Haftverbindungen und anwendungsverfahren für herniereparatur |
WO2013055891A1 (en) * | 2011-10-11 | 2013-04-18 | Knee Creations Llc. | Methods and instruments for subchondral treatment of osteoarthritis in a small joint |
US20130202656A1 (en) | 2012-02-03 | 2013-08-08 | Dynasil Biomedical Corporation | Systems and kits for the fabrication of tissue patches |
US20140178343A1 (en) | 2012-12-21 | 2014-06-26 | Jian Q. Yao | Supports and methods for promoting integration of cartilage tissue explants |
US10390838B1 (en) | 2014-08-20 | 2019-08-27 | Pneumrx, Inc. | Tuned strength chronic obstructive pulmonary disease treatment |
US10077420B2 (en) | 2014-12-02 | 2018-09-18 | Histogenics Corporation | Cell and tissue culture container |
AU2016307447A1 (en) | 2015-08-07 | 2018-02-22 | Xcede Technologies, Inc. | Adhesive compositions and related methods |
US9833538B2 (en) | 2015-08-07 | 2017-12-05 | Xcede Technologies, Inc. | Adhesive compositions and related methods |
US9540548B1 (en) | 2015-08-07 | 2017-01-10 | Xcede Technologies, Inc. | Adhesive compositions and related methods |
WO2017223462A1 (en) * | 2016-06-24 | 2017-12-28 | President And Fellows Of Harvard College | Composition and method for adhering biomaterials to a target surface |
WO2018140855A1 (en) * | 2017-01-30 | 2018-08-02 | Lifecell Corporation | Devices including muscle matrix and methods of production and use |
JP2020513944A (ja) * | 2017-01-30 | 2020-05-21 | ライフセル コーポレーションLifeCell Corporation | 組織マトリックス材料および酵素接着剤 |
US10413634B2 (en) | 2017-01-30 | 2019-09-17 | Lifecell Corporation | Transglutaminase treated products |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2949407A1 (de) * | 1979-12-07 | 1981-06-11 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur gewinnung von (alpha) -2-sb-glykoprotein |
DE3113986A1 (de) * | 1981-04-07 | 1982-10-21 | Robert Bosch Gmbh, 7000 Stuttgart | Vorrichtung zur regelung der leerlaufdrehzahl einer brennkraftmaschine |
US4582794A (en) * | 1982-09-15 | 1986-04-15 | The University Of Arizona Foundation | Method of determining polyamine content of biological fluids |
US4728643A (en) * | 1984-11-02 | 1988-03-01 | The General Hospital Corporation | Method of treating psoriasis |
US5037816A (en) * | 1984-11-02 | 1991-08-06 | The General Hospital Corporation | Method of treating psoriasis |
AU2423988A (en) * | 1987-08-17 | 1989-03-09 | Liposome Company, Inc., The | A sponge enzyme having transglutaminase-like activity |
US4968713A (en) * | 1989-07-31 | 1990-11-06 | Merck & Co., Inc. | Certain imidazole compounds as transglutaminase inhibitors |
WO1992012238A1 (en) * | 1991-01-04 | 1992-07-23 | The Board Of Regents, University Of Texas System | Cloning and expression of tissue transglutaminases |
US5206023A (en) * | 1991-01-31 | 1993-04-27 | Robert F. Shaw | Method and compositions for the treatment and repair of defects or lesions in cartilage |
US5270300A (en) * | 1991-09-06 | 1993-12-14 | Robert Francis Shaw | Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone |
-
1993
- 1993-06-03 US US08/071,528 patent/US5549904A/en not_active Expired - Lifetime
-
1994
- 1994-06-03 ES ES94919328T patent/ES2194869T3/es not_active Expired - Lifetime
- 1994-06-03 AT AT94919328T patent/ATE234643T1/de not_active IP Right Cessation
- 1994-06-03 CA CA002163250A patent/CA2163250A1/en not_active Abandoned
- 1994-06-03 WO PCT/US1994/006208 patent/WO1994028949A1/en active IP Right Grant
- 1994-06-03 AU AU70511/94A patent/AU7051194A/en not_active Abandoned
- 1994-06-03 EP EP94919328A patent/EP0702572B1/de not_active Expired - Lifetime
- 1994-06-03 JP JP50193595A patent/JP3483255B2/ja not_active Expired - Fee Related
- 1994-06-03 DE DE69432300T patent/DE69432300T2/de not_active Expired - Fee Related
- 1994-06-06 TW TW083105136A patent/TW404836B/zh not_active IP Right Cessation
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1996
- 1996-01-29 US US08/592,921 patent/US5736132A/en not_active Expired - Lifetime
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1998
- 1998-09-01 AU AU83055/98A patent/AU8305598A/en not_active Abandoned
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ATE234643T1 (de) | 2003-04-15 |
WO1994028949A1 (en) | 1994-12-22 |
US5736132A (en) | 1998-04-07 |
ES2194869T3 (es) | 2003-12-01 |
AU7051194A (en) | 1995-01-03 |
TW404836B (en) | 2000-09-11 |
DE69432300T2 (de) | 2004-02-12 |
JPH08510943A (ja) | 1996-11-19 |
AU8305598A (en) | 1999-04-29 |
JP3483255B2 (ja) | 2004-01-06 |
US5549904A (en) | 1996-08-27 |
EP0702572A1 (de) | 1996-03-27 |
CA2163250A1 (en) | 1994-12-22 |
EP0702572B1 (de) | 2003-03-19 |
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