DE69434924D1 - Verbindungen zur photodekontamination von pathogenen erregern im blut - Google Patents

Verbindungen zur photodekontamination von pathogenen erregern im blut

Info

Publication number
DE69434924D1
DE69434924D1 DE69434924T DE69434924T DE69434924D1 DE 69434924 D1 DE69434924 D1 DE 69434924D1 DE 69434924 T DE69434924 T DE 69434924T DE 69434924 T DE69434924 T DE 69434924T DE 69434924 D1 DE69434924 D1 DE 69434924D1
Authority
DE
Germany
Prior art keywords
compounds
psoralen
blood
photodecontamination
pathogens
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69434924T
Other languages
English (en)
Other versions
DE69434924T2 (de
Inventor
Susan Wollowitz
Stephen T Isaacs
Henry Rapoport
Hans Peter Spielman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cerus Corp
Original Assignee
Cerus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cerus Corp filed Critical Cerus Corp
Publication of DE69434924D1 publication Critical patent/DE69434924D1/de
Application granted granted Critical
Publication of DE69434924T2 publication Critical patent/DE69434924T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0215—Disinfecting agents, e.g. antimicrobials for preserving living parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0066—Psoralene-activated UV-A photochemotherapy (PUVA-therapy), e.g. for treatment of psoriasis or eczema, extracorporeal photopheresis with psoralens or fucocoumarins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/10—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
    • A61K41/17—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
DE69434924T 1993-06-28 1994-06-24 Verbindungen zur photodekontamination von pathogenen erregern im blut Expired - Lifetime DE69434924T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/083,459 US5399719A (en) 1993-06-28 1993-06-28 Compounds for the photodecontamination of pathogens in blood
US83459 1993-06-28
PCT/US1994/007185 WO1995000141A1 (en) 1993-06-28 1994-06-24 Compounds for the photodecontamination of pathogens in blood

Publications (2)

Publication Number Publication Date
DE69434924D1 true DE69434924D1 (de) 2007-03-29
DE69434924T2 DE69434924T2 (de) 2007-11-22

Family

ID=22178486

Family Applications (3)

Application Number Title Priority Date Filing Date
DE200712000052 Pending DE122007000052I1 (de) 1993-06-28 1994-06-24 Verbindungen zur Photodekontamination von pathogenen Erregern im Blut
DE69435250T Expired - Lifetime DE69435250D1 (de) 1993-06-28 1994-06-24 Verbindungen zur Photodekontamination von pathogenen Erregern im Blut
DE69434924T Expired - Lifetime DE69434924T2 (de) 1993-06-28 1994-06-24 Verbindungen zur photodekontamination von pathogenen erregern im blut

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE200712000052 Pending DE122007000052I1 (de) 1993-06-28 1994-06-24 Verbindungen zur Photodekontamination von pathogenen Erregern im Blut
DE69435250T Expired - Lifetime DE69435250D1 (de) 1993-06-28 1994-06-24 Verbindungen zur Photodekontamination von pathogenen Erregern im Blut

Country Status (10)

Country Link
US (6) US5399719A (de)
EP (3) EP1584622B1 (de)
JP (1) JP4047374B2 (de)
AT (2) ATE353643T1 (de)
AU (1) AU699805B2 (de)
CA (1) CA2165984C (de)
DE (3) DE122007000052I1 (de)
ES (2) ES2282991T3 (de)
HK (1) HK1083493A1 (de)
WO (1) WO1995000141A1 (de)

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Also Published As

Publication number Publication date
DE69435250D1 (de) 2009-12-24
DE122007000052I1 (de) 2007-11-08
US5654443A (en) 1997-08-05
EP0707476A1 (de) 1996-04-24
US5399719A (en) 1995-03-21
ATE353643T1 (de) 2007-03-15
US5972593A (en) 1999-10-26
JPH08512032A (ja) 1996-12-17
EP1776952A3 (de) 2007-05-02
CA2165984C (en) 2004-01-20
CA2165984A1 (en) 1995-01-05
EP1584622A2 (de) 2005-10-12
AU699805B2 (en) 1998-12-17
AU7251194A (en) 1995-01-17
EP0707476A4 (de) 1998-12-23
WO1995000141A1 (en) 1995-01-05
EP1584622B1 (de) 2009-11-11
ATE448233T1 (de) 2009-11-15
EP1776952A2 (de) 2007-04-25
EP0707476B1 (de) 2007-02-14
ES2282991T3 (es) 2007-10-16
EP1584622A3 (de) 2007-10-17
DE69434924T2 (de) 2007-11-22
US6503699B1 (en) 2003-01-07
US5585503A (en) 1996-12-17
HK1083493A1 (en) 2006-07-07
ES2336574T3 (es) 2010-04-14
JP4047374B2 (ja) 2008-02-13
US5578736A (en) 1996-11-26

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