DE69517816D1 - Matrix für transdermale wirkstofffreisetzung - Google Patents

Matrix für transdermale wirkstofffreisetzung

Info

Publication number
DE69517816D1
DE69517816D1 DE69517816T DE69517816T DE69517816D1 DE 69517816 D1 DE69517816 D1 DE 69517816D1 DE 69517816 T DE69517816 T DE 69517816T DE 69517816 T DE69517816 T DE 69517816T DE 69517816 D1 DE69517816 D1 DE 69517816D1
Authority
DE
Germany
Prior art keywords
matrix
active substance
substance release
transdermal active
softener
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE69517816T
Other languages
English (en)
Other versions
DE69517816T2 (de
Inventor
E Garbe
C Duan
L Moore
C Keister
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3M Co
Original Assignee
Minnesota Mining and Manufacturing Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23182561&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69517816(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Minnesota Mining and Manufacturing Co filed Critical Minnesota Mining and Manufacturing Co
Publication of DE69517816D1 publication Critical patent/DE69517816D1/de
Application granted granted Critical
Publication of DE69517816T2 publication Critical patent/DE69517816T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/04—Polymers provided for in subclasses C08C or C08F
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J155/00—Adhesives based on homopolymers or copolymers, obtained by polymerisation reactions only involving carbon-to-carbon unsaturated bonds, not provided for in groups C09J123/00 - C09J153/00
    • C09J155/005—Homopolymers or copolymers obtained by polymerisation of macromolecular compounds terminated by a carbon-to-carbon double bond
DE69517816T 1994-09-14 1995-09-12 Matrix für transdermale wirkstofffreisetzung Revoked DE69517816T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30583394A 1994-09-14 1994-09-14
PCT/US1995/012163 WO1996008229A2 (en) 1994-09-14 1995-09-12 Matrix for transdermal drug delivery

Publications (2)

Publication Number Publication Date
DE69517816D1 true DE69517816D1 (de) 2000-08-10
DE69517816T2 DE69517816T2 (de) 2000-12-28

Family

ID=23182561

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69517816T Revoked DE69517816T2 (de) 1994-09-14 1995-09-12 Matrix für transdermale wirkstofffreisetzung

Country Status (14)

Country Link
US (2) US7097853B1 (de)
EP (1) EP0781122B1 (de)
JP (1) JP4102901B2 (de)
KR (1) KR100382706B1 (de)
AT (1) ATE194281T1 (de)
AU (1) AU702593B2 (de)
CA (1) CA2198390C (de)
DE (1) DE69517816T2 (de)
DK (1) DK0781122T3 (de)
ES (1) ES2147858T3 (de)
GR (1) GR3033859T3 (de)
NZ (1) NZ293849A (de)
PT (1) PT781122E (de)
WO (1) WO1996008229A2 (de)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4580682A (en) * 1983-01-31 1986-04-08 North American Science Associates, Inc. Self-contained indicator device
DE19526864A1 (de) * 1995-07-22 1997-01-23 Labtec Gmbh Hormonpflaster
US5703169A (en) * 1996-01-24 1997-12-30 Adhesives Research, Inc. Non-corrosive, low volatiles-containing pressure sensitive adhesive
DE19629468A1 (de) * 1996-07-11 1998-01-15 Schering Ag Transdermale therapeutische Systeme
US5951999A (en) 1997-02-21 1999-09-14 Adhesives Research, Inc. Transdermal pressure sensitive adhesive drug delivery system
WO1998053815A1 (en) * 1997-05-30 1998-12-03 Minnesota Mining And Manufacturing Company Transdermal drug delivery device for the delivery of tropisetron or granisetron
DE19728516C2 (de) * 1997-07-04 1999-11-11 Sanol Arznei Schwarz Gmbh TTS zur Verabreichung von Levonorgestrel und gegebenenfalls Estradiol
MY122454A (en) 1998-06-05 2006-04-29 Upjohn Co Use of oxazolidinones for the preparation of a medicament for transdermal delivery
US6136807A (en) * 1998-11-10 2000-10-24 3M Innovative Properties Company Composition for the transdermal delivery of lerisetron
US20030139384A1 (en) * 2000-08-30 2003-07-24 Dudley Robert E. Method for treating erectile dysfunction and increasing libido in men
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
KR100940245B1 (ko) * 2000-09-19 2010-02-04 내쇼날 스타치 앤드 케미칼 인베스트멘트 홀딩 코포레이션 경피 약물 전달 시스템에 유용한 비반응성 접착제
CA2422267C (en) * 2000-09-24 2010-02-16 3M Innovative Properties Company Drying method for selectively removing volatile components from wet coatings
AU2007205756B2 (en) * 2000-09-29 2010-04-15 Kindeva Drug Delivery L.P. Composition for the transdermal delivery of fentanyl
US20020119187A1 (en) * 2000-09-29 2002-08-29 Cantor Adam S. Composition for the transdermal delivery of fentanyl
US6479076B2 (en) * 2001-01-12 2002-11-12 Izhak Blank Nicotine delivery compositions
DE20221247U1 (de) * 2001-03-16 2005-09-15 Alza Corp Transdermal-Pflaster zum Verabreichen von Fentanyl
RU2708563C2 (ru) 2001-03-16 2019-12-10 Алза Корпорейшн Трансдермальный пластырь для введения фентанила
US6902740B2 (en) * 2001-07-09 2005-06-07 3M Innovative Properties Company Pyrrolidonoethyl (meth)acrylate containing pressure sensitive adhesive compositions
DE10141650C1 (de) * 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
US6893655B2 (en) 2001-10-09 2005-05-17 3M Innovative Properties Co. Transdermal delivery devices
BR0308584A (pt) * 2002-03-15 2005-02-22 Unimed Pharmaceuticals Inc Composição farmacêutica androgênica e método para tratamento de depressão
JP4746984B2 (ja) * 2003-03-28 2011-08-10 独立行政法人科学技術振興機構 生体適合性と温度応答性を併せ持つ高分子
JP4567998B2 (ja) * 2004-03-22 2010-10-27 コスメディ製薬株式会社 親水性粘着剤を用いた親水性皮膚外用粘着剤組成物および親水性貼付剤
IL177071A0 (en) * 2005-08-01 2006-12-10 Nitto Denko Corp Method of preparing a nicotine transdermal preparation
EP1928537B1 (de) * 2005-09-02 2015-01-21 Intercell USA, Inc. Vorrichtungen für die transkutane Abgabe von Vakzine und transdermale Abgabe von Arzneimittel
WO2007035939A2 (en) 2005-09-23 2007-03-29 Alza Corporation High enhancer-loading polyacrylate formulation for transdermal applications
US9056061B2 (en) 2005-09-23 2015-06-16 Alza Corporation Transdermal nicotine salt delivery system
AU2006299833B2 (en) 2005-10-12 2012-04-12 Besins Healthcare Luxembourg Sarl Improved testosterone gel and method of use
ES2499067T3 (es) 2005-10-13 2014-09-26 Nitto Denko Corporation Preparación transdérmica de nicotina y método de producción de la misma
JP5188680B2 (ja) * 2006-04-10 2013-04-24 花王株式会社 生分解性樹脂用可塑剤
JP5241714B2 (ja) 2006-07-07 2013-07-17 プロテウス デジタル ヘルス， インコーポレイテッド スマートな非経口送達システム
EP2211974A4 (de) 2007-10-25 2013-02-27 Proteus Digital Health Inc Informationssystem für flüssigkeitsüberströmkanal
US20090124952A1 (en) * 2007-11-09 2009-05-14 Berman David A Herpes Treatment and Dressing
US8419638B2 (en) 2007-11-19 2013-04-16 Proteus Digital Health, Inc. Body-associated fluid transport structure evaluation devices
BRPI0913214B1 (pt) * 2008-05-30 2022-05-17 Mylan Laboratories Inc Dispositivo de fornecimento de drogas transdérmico e método de fabricação do mesmo
KR101264843B1 (ko) * 2008-12-31 2013-05-16 주식회사 삼양바이오팜 휘발성 약물 또는 열에 약한 약물의 경피 투여용 패치 제조방법 및 그 경피 패치
US8701671B2 (en) 2011-02-04 2014-04-22 Joseph E. Kovarik Non-surgical method and system for reducing snoring
US9549842B2 (en) 2011-02-04 2017-01-24 Joseph E. Kovarik Buccal bioadhesive strip and method of treating snoring and sleep apnea
AU2011210648B2 (en) 2010-02-01 2014-10-16 Otsuka Pharmaceutical Co., Ltd. Data gathering system
US8332020B2 (en) 2010-02-01 2012-12-11 Proteus Digital Health, Inc. Two-wrist data gathering system
ES2720952T3 (es) 2010-07-21 2019-07-25 3M Innovative Properties Co Composiciones adhesivas transdérmicas, dispositivos y métodos
US11951139B2 (en) 2015-11-30 2024-04-09 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US11951140B2 (en) 2011-02-04 2024-04-09 Seed Health, Inc. Modulation of an individual's gut microbiome to address osteoporosis and bone disease
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis
CA2856520C (en) 2011-11-23 2021-04-06 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
JP6120873B2 (ja) 2011-12-13 2017-04-26 スリーエム イノベイティブ プロパティズ カンパニー 活性剤を含む感圧接着剤物品を製造する方法
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
EP2712612B1 (de) * 2012-09-28 2020-03-25 Nitto Denko Corporation Pflasterpräparat mir Aminoxid und Isopropylmyristat
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
JP6186994B2 (ja) * 2013-07-29 2017-08-30 三菱ケミカル株式会社 アクリル系樹脂組成物
WO2015054059A2 (en) 2013-10-07 2015-04-16 Teikoku Pharma Usa, Inc. Methods and compositions for treating attention deficit hyperactivity disorder, anxiety and insomnia using dexmedetomidine transdermal compositions
TWI629067B (zh) 2013-10-07 2018-07-11 美商帝國製藥美國股份有限公司 用於經皮輸送非鎮靜量右美托咪啶之方法及組成物
CA2924231C (en) * 2013-10-07 2018-04-03 Teikoku Pharma Usa, Inc. Dexmedetomidine transdermal delivery devices and methods for using the same
US11839632B2 (en) 2013-12-20 2023-12-12 Seed Health, Inc. Topical application of CRISPR-modified bacteria to treat acne vulgaris
US11826388B2 (en) 2013-12-20 2023-11-28 Seed Health, Inc. Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation
US11833177B2 (en) 2013-12-20 2023-12-05 Seed Health, Inc. Probiotic to enhance an individual's skin microbiome
MX2016014281A (es) 2014-05-22 2017-02-22 Therapeuticsmd Inc Formulaciones y terapias de reemplazo de combinación de hormonas naturales.
CN107001873B (zh) 2014-12-16 2021-06-29 3M创新有限公司 具有阻挡层的粘合剂制品
EP3233081B1 (de) 2014-12-19 2021-09-22 Kindeva Drug Delivery L.P. Transdermale arzneimittelverabreichungsvorrichtung enthaltend fentanyl
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
WO2017173071A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
WO2017223402A1 (en) 2016-06-23 2017-12-28 Corium International, Inc. Adhesive matrix with hydrophilic and hydrophobic domains and a therapeutic agent
AU2017302306A1 (en) 2016-07-27 2019-02-14 Corium, LLC. Transdermal formulation and delivery method of low solubility or unstable unionized neutral drugs by in situ salt-to-neutral drug conversion of salt drug
EP3490559A1 (de) 2016-07-27 2019-06-05 Corium International, Inc. Transdermales verabreichungssystem mit bioäquivalenter pharmakokinetik zur oralen verabreichung
KR102508993B1 (ko) 2016-07-27 2023-03-10 코리움, 인크. 메만틴 경피 송달 시스템
US11173132B2 (en) 2017-12-20 2021-11-16 Corium, Inc. Transdermal adhesive composition comprising a volatile liquid therapeutic agent having low melting point
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations
JP2023519959A (ja) * 2020-03-30 2023-05-15 シンケイ セラピューティクス インコーポレイテッド デキストロメトルファンの経皮送達

Family Cites Families (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA677797A (en) 1955-11-18 1964-01-14 Minnesota Mining And Manufacturing Company Sheet material having a pressure-sensitive adhesive coating of acrylate ester copolymer
US3862102A (en) 1971-02-22 1975-01-21 Cpc International Inc Alpha-olefin terminated polydiene macromolecular monomers having a substantially uniform molecular weight distribution
US3842146A (en) 1971-02-22 1974-10-15 Cpc International Inc Polymerizable diblock macromolecular monomers having a substantially uniform molecular weight distribution and their preparation
US3832423A (en) 1971-02-22 1974-08-27 Cpc International Inc Chemically joined, phase separated graft copolymers having hydrocarbon polymeric backbones
US3879494A (en) 1971-02-22 1975-04-22 Cpc International Inc Polyblends of chemically joined, phase separated thermoplastic graft copolymers
US3862077A (en) 1971-02-22 1975-01-21 Cpc International Inc Stable latexes of a chemically joined, phase separated thermoplastic graft copolymer and method for preparing the same
US3842057A (en) 1971-02-22 1974-10-15 Cpc International Inc Vinyl ester terminated macromolecular monomers having a substantially uniform molecular weight distribution and process for preparing same
US3862101A (en) 1971-02-22 1975-01-21 Cpc International Inc Acrylate and methacrylate terminated polydiene macromolecular monomers having a substantially uniform molecular weight distribution
US3842058A (en) 1971-02-22 1974-10-15 Cpc International Inc Vinyl ether terminated polystyrene macromolecular monomers having a substantially uniform molecular weight distribution
US3862098A (en) 1971-02-22 1975-01-21 Cpc International Inc Alpha-olefin terminated polystyrene macromolecular monomers having a substantially uniform molecular weight distribution
US4085168A (en) 1971-02-22 1978-04-18 Cpc International Inc. Chemically joined, phase separated self-cured hydrophilic thermoplastic graft copolymers and their preparation
US3842059A (en) 1971-02-22 1974-10-15 M Chiang Acrylate and methacrylate terminated polystyrene macromolecular monomers having a substantially uniform molecular weight distribution
US3989768A (en) 1971-02-22 1976-11-02 Cpc International Inc. Chemically joined phase separated thermoplastic graft copolymers
US3928255A (en) 1971-02-22 1975-12-23 Cpc International Inc Chemically joined, phase separated self-cured hydrophilic thermoplastic graft copolymers and their preparation
US3786116A (en) 1972-08-21 1974-01-15 Cpc International Inc Chemically joined,phase separated thermoplastic graft copolymers
US4304591A (en) 1978-01-25 1981-12-08 Ciba-Geigy Corporation Water-insoluble hydrophilic copolymers used as carriers for medicaments and pesticides
US4260659A (en) 1979-06-18 1981-04-07 Minnesota Mining And Manufacturing Company Pressure-sensitive tape having a plurality of adhesive layers
JPS596284B2 (ja) * 1980-06-26 1984-02-10 積水化学工業株式会社 治療用接着テ−プもしくはシ−ト
JPS57125753A (en) 1981-01-30 1982-08-05 Sekisui Chemical Co Ltd Therapeutic adhesive tape or sheet
GB2105990B (en) 1981-08-27 1985-06-19 Nitto Electric Ind Co Adhesive skin patches
US4374883A (en) 1981-10-15 1983-02-22 Minnesota Mining And Manufacturing Company Pressure-sensitive adhesive tape
JPS58176208A (ja) 1982-04-09 1983-10-15 Dainippon Ink & Chem Inc 塗料用樹脂組成物
US4554324A (en) 1982-09-16 1985-11-19 Minnesota Mining And Manufacturing Co. Acrylate copolymer pressure-sensitive adhesive composition and sheet materials coated therewith
US4551388A (en) 1983-06-27 1985-11-05 Atlantic Richfield Company Acrylic hot melt pressure sensitive adhesive coated sheet material
JPS60228413A (ja) 1984-04-27 1985-11-13 Sekisui Chem Co Ltd 治療用テ−プもしくはシ−ト及びその製造方法
US4656213A (en) 1984-10-26 1987-04-07 Atlantic Richfield Company Acrylic hot melt pressure sensitive adhesive compounds
US4818540A (en) 1985-02-25 1989-04-04 Rutgers, The State University Of New Jersey Transdermal fertility control system and process
US5296230A (en) 1985-02-25 1994-03-22 Rutgers, The State University Of New Jersey Transdermal fertility control system and process
US4883669A (en) 1985-02-25 1989-11-28 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit for estradiol and other estrogenic steroids and process for administration
US4751087A (en) * 1985-04-19 1988-06-14 Riker Laboratories, Inc. Transdermal nitroglycerin delivery system
US4693776A (en) 1985-05-16 1987-09-15 Minnesota Mining And Manufacturing Company Macromer reinforced pressure sensitive skin adhesive
US4732808A (en) * 1985-11-14 1988-03-22 Minnesota Mining And Manufacturing Company Macromer reinforced pressure sensitive skin adhesive sheet material
US4737559A (en) 1986-05-19 1988-04-12 Minnesota Mining And Manufacturing Co. Pressure-sensitive adhesive crosslinked by copolymerizable aromatic ketone monomers
US4847137A (en) 1986-05-19 1989-07-11 Minnesota Mining And Manufacturing Company Pressure-sensitive adhesive crosslinked by copolymerizable aromatic ketone monomers
US5145682A (en) 1986-05-30 1992-09-08 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit for postmenopausal syndrome treatment and process for administration
US4851278A (en) 1986-08-11 1989-07-25 Minnesota Mining And Manufacturing Company Acrylate hot melt adhesive containing zinc carboxylate
US4871812A (en) 1986-11-28 1989-10-03 Minnesota Mining And Manufacturing Company Moldable medical adhesive
US4906169A (en) 1986-12-29 1990-03-06 Rutgers, The State University Of New Jersey Transdermal estrogen/progestin dosage unit, system and process
US5023084A (en) 1986-12-29 1991-06-11 Rutgers, The State University Of New Jersey Transdermal estrogen/progestin dosage unit, system and process
US5229195A (en) 1987-08-26 1993-07-20 Lintec Corporation Composite body having a blister-free pressure-sensitive adhesive sheet attached thereto
US5225473A (en) * 1987-11-25 1993-07-06 Minnesota Mining And Manufacturing Company Pressure-sensitive adhesives
JPH01213379A (ja) 1988-02-22 1989-08-28 Nitto Denko Corp 感圧性接着剤
US5223261A (en) * 1988-02-26 1993-06-29 Riker Laboratories, Inc. Transdermal estradiol delivery system
US4994267A (en) 1988-03-04 1991-02-19 Noven Pharmaceuticals, Inc. Transdermal acrylic multipolymer drug delivery system
US5175052A (en) 1988-05-11 1992-12-29 Nitto Denko Corporation Adhesive tape preparation of clonidine
US4946742A (en) 1988-05-20 1990-08-07 Minnesota Mining And Manufacturing Company Pressure-sensitive adhesive having improved adhesion to plasticized vinyl substrates
US5006582A (en) 1988-08-01 1991-04-09 E. I. Du Pont De Nemours And Company Acrylic hot melt pressure sensitive adhesive compositions
EP0353677B1 (de) 1988-08-04 1995-04-05 LINTEC Corporation Kunststoffplatte und dafür geeigneter Klebefilm
DE68920109T2 (de) 1988-10-11 1995-05-11 Shire Holdings Ltd Arzneimittelpräparat für perkutane Absorption.
US5008110A (en) * 1988-11-10 1991-04-16 The Procter & Gamble Company Storage-stable transdermal patch
DE3844247A1 (de) * 1988-12-29 1990-07-12 Minnesota Mining & Mfg Vorrichtung, insbesondere pflaster zum transdermalen verabreichen eines medikaments
US5053227A (en) 1989-03-22 1991-10-01 Cygnus Therapeutic Systems Skin permeation enhancer compositions, and methods and transdermal systems associated therewith
US5059426A (en) 1989-03-22 1991-10-22 Cygnus Therapeutic Systems Skin permeation enhancer compositions, and methods and transdermal systems associated therewith
US4973468A (en) 1989-03-22 1990-11-27 Cygnus Research Corporation Skin permeation enhancer compositions
EP0399432B1 (de) 1989-05-25 1994-06-22 Takeda Chemical Industries, Ltd. Transdermales therapeutisches Mittel
US5262165A (en) 1992-02-04 1993-11-16 Schering Corporation Transdermal nitroglycerin patch with penetration enhancers
US4994322A (en) 1989-09-18 1991-02-19 Minnesota Mining And Manufacturing Pressure-sensitive adhesive comprising hollow tacky microspheres and macromonomer-containing binder copolymer
US5298258A (en) 1989-12-28 1994-03-29 Nitto Denko Corporation Acrylic oily gel bioadhesive material and acrylic oily gel preparation
US5032637A (en) 1990-03-14 1991-07-16 Adhesives Research Inc. Water-inactivatable pressure sensitive adhesive
JP2849937B2 (ja) 1990-04-18 1999-01-27 日東電工株式会社 医療用貼付剤
CA2039586A1 (en) 1990-05-02 1991-11-03 Marian R. Appelt Crosslinked pressure-sensitive adhesives tolerant of alcohol-based excipients used in transdermal delivery devices and method of preparing same
US5143972A (en) 1990-05-17 1992-09-01 Minnesota Mining And Manufacturing Company Pressure-sensitive adhesive composition
DE4020144A1 (de) 1990-06-25 1992-01-09 Lohmann Therapie Syst Lts Pflaster mit hohem gehalt an weichmachenden inhaltsstoffen
JP2849950B2 (ja) 1990-11-30 1999-01-27 日東電工株式会社 経皮吸収製剤
JPH04216886A (ja) 1990-12-17 1992-08-06 Lintec Corp 耐ブリスター性粘着シート
AU641580B2 (en) 1991-02-28 1993-09-23 National Starch And Chemical Investment Holding Corporation Water vapor permeable pressure sensitive adhesive composition
WO1993006184A1 (en) 1991-09-23 1993-04-01 Minnesota Mining And Manufacturing Company PRESSURE SENSITIVE ADHESIVE COMPOSITION WHICH IS REPULPABLE UNDER ACIDIC pH CONDITIONS
US5276079A (en) * 1991-11-15 1994-01-04 Minnesota Mining And Manufacturing Company Pressure-sensitive poly(n-vinyl lactam) adhesive composition and method for producing and using same
US5352516A (en) 1992-01-31 1994-10-04 Adhesives Research, Inc. Water-inactivatable pressure sensitive adhesive
US5302629A (en) * 1992-05-15 1994-04-12 Berejka Anthony J Hydrophilic acrylic pressure sensitive adhesives
US5264219A (en) 1992-08-07 1993-11-23 Minnesota Mining And Manufacturing Company Transdermal drug delivery backing
US5489624A (en) 1992-12-01 1996-02-06 Minnesota Mining And Manufacturing Company Hydrophilic pressure sensitive adhesives
SG49755A1 (en) 1992-12-07 1998-06-15 Minnesota Mining & Mfg Adhesive for polycarbonate
US5395907A (en) 1993-11-29 1995-03-07 Adhesive Research, Inc. Water-soluble pressure sensitive adhesive
US5508367A (en) 1993-11-29 1996-04-16 Adhesives Research, Inc. Water-soluble pressure sensitive adhesive
US5573778A (en) 1995-03-17 1996-11-12 Adhesives Research, Inc. Drug flux enhancer-tolerant pressure sensitive adhesive composition
US5614210A (en) 1995-03-31 1997-03-25 Minnesota Mining And Manufacturing Company Transdermal device for the delivery of alfuzosin

Also Published As

Publication number Publication date
DK0781122T3 (da) 2000-10-30
AU3639795A (en) 1996-03-29
US7097853B1 (en) 2006-08-29
AU702593B2 (en) 1999-02-25
NZ293849A (en) 1998-10-28
US20060099242A1 (en) 2006-05-11
JPH10508296A (ja) 1998-08-18
ATE194281T1 (de) 2000-07-15
CA2198390C (en) 2009-08-11
KR100382706B1 (ko) 2003-10-10
JP4102901B2 (ja) 2008-06-18
EP0781122A2 (de) 1997-07-02
GR3033859T3 (en) 2000-10-31
ES2147858T3 (es) 2000-10-01
EP0781122B1 (de) 2000-07-05
PT781122E (pt) 2000-11-30
CA2198390A1 (en) 1996-03-21
WO1996008229A3 (en) 1996-07-25
WO1996008229A2 (en) 1996-03-21
DE69517816T2 (de) 2000-12-28
KR970705974A (ko) 1997-11-03

Similar Documents

Publication Publication Date Title
DE69517816D1 (de) Matrix für transdermale wirkstofffreisetzung
NO982764L (no) Oppfinnelse og anordning for transdermal anordning for avgivelse av flurbiprofen
NZ316026A (en) A transdermal therapeutic system (a hormone patch) in which drugs are contained which are released into the skin comprising a backing film and a pressure sensitive adhesive
DE69426988D1 (de) Transdermale abgabe vorrichtung
ZA977832B (en) Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents.
IL113611A0 (en) A device for the release of subtances from pressure-sensitive hot-melt adhesives
NZ333558A (en) Transdermal drug delivery matrix for coadministering estradiol and another sex steroid
BR9506470B8 (pt) Composição adesiva sensível à pressão e sistema de distribuição transdérmica de droga.
BR9407238A (pt) Dispositivo implantável de fornecimento de droga
DK0596903T3 (da) Transdermale, terapeutiske systemer.
NO941593D0 (de)
DE69824600D1 (de) Minimal-invasive anzeige-vorrichtung

Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation