DE69524232D1 - Polynukleotid reagenzien mit nichtnukleotidischen gruppierungen, deren herstellung und verwendung - Google Patents

Polynukleotid reagenzien mit nichtnukleotidischen gruppierungen, deren herstellung und verwendung

Info

Publication number
DE69524232D1
DE69524232D1 DE69524232T DE69524232T DE69524232D1 DE 69524232 D1 DE69524232 D1 DE 69524232D1 DE 69524232 T DE69524232 T DE 69524232T DE 69524232 T DE69524232 T DE 69524232T DE 69524232 D1 DE69524232 D1 DE 69524232D1
Authority
DE
Germany
Prior art keywords
nucleotidic
groups
production
polynucleotide reagents
polynucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69524232T
Other languages
English (en)
Other versions
DE69524232T2 (de
Inventor
S Urdea
Thomas Horn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Corp
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Application granted granted Critical
Publication of DE69524232D1 publication Critical patent/DE69524232D1/de
Publication of DE69524232T2 publication Critical patent/DE69524232T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65515Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6823Release of bound markers
DE69524232T 1994-08-25 1995-08-24 Polynukleotid reagenzien mit nichtnukleotidischen gruppierungen, deren herstellung und verwendung Expired - Fee Related DE69524232T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/296,368 US5597909A (en) 1994-08-25 1994-08-25 Polynucleotide reagents containing modified deoxyribose moieties, and associated methods of synthesis and use
PCT/US1995/010776 WO1996006104A1 (en) 1994-08-25 1995-08-24 Polynucleotide reagents having nonnucleotidic moieties, and associated methods of synthesis and use

Publications (2)

Publication Number Publication Date
DE69524232D1 true DE69524232D1 (de) 2002-01-10
DE69524232T2 DE69524232T2 (de) 2002-05-23

Family

ID=23141731

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69524232T Expired - Fee Related DE69524232T2 (de) 1994-08-25 1995-08-24 Polynukleotid reagenzien mit nichtnukleotidischen gruppierungen, deren herstellung und verwendung

Country Status (10)

Country Link
US (2) US5597909A (de)
EP (1) EP0777674B1 (de)
JP (2) JPH10504719A (de)
AT (1) ATE209655T1 (de)
AU (1) AU3494595A (de)
CA (1) CA2196806A1 (de)
DE (1) DE69524232T2 (de)
ES (1) ES2169149T3 (de)
MX (1) MX9701293A (de)
WO (1) WO1996006104A1 (de)

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US5597909A (en) 1997-01-28
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