DE69526855D1 - Krebstest, in welchem eine vom H19-Gen abgeleitete Sonde verwendet wird - Google Patents

Krebstest, in welchem eine vom H19-Gen abgeleitete Sonde verwendet wird

Info

Publication number
DE69526855D1
DE69526855D1 DE69526855T DE69526855T DE69526855D1 DE 69526855 D1 DE69526855 D1 DE 69526855D1 DE 69526855 T DE69526855 T DE 69526855T DE 69526855 T DE69526855 T DE 69526855T DE 69526855 D1 DE69526855 D1 DE 69526855D1
Authority
DE
Germany
Prior art keywords
gene
probe derived
cancer test
cancer
test
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69526855T
Other languages
English (en)
Other versions
DE69526855T2 (de
Inventor
Abraham Hochberg
Ilana Ariel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hadasit Medical Research Services and Development Co
Yissum Research Development Co of Hebrew University of Jerusalem
Original Assignee
Hadasit Medical Research Services and Development Co
Yissum Research Development Co of Hebrew University of Jerusalem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hadasit Medical Research Services and Development Co, Yissum Research Development Co of Hebrew University of Jerusalem filed Critical Hadasit Medical Research Services and Development Co
Application granted granted Critical
Publication of DE69526855D1 publication Critical patent/DE69526855D1/de
Publication of DE69526855T2 publication Critical patent/DE69526855T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
DE69526855T 1994-03-07 1995-03-06 Krebstest, in welchem eine vom H19-Gen abgeleitete Sonde verwendet wird Expired - Lifetime DE69526855T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL10887994A IL108879A (en) 1994-03-07 1994-03-07 Diagnostic assay for malignancies using the H19 gene and kit
PCT/EP1995/000823 WO1995024503A1 (en) 1994-03-07 1995-03-06 Sensitive cancer test

Publications (2)

Publication Number Publication Date
DE69526855D1 true DE69526855D1 (de) 2002-07-04
DE69526855T2 DE69526855T2 (de) 2002-11-28

Family

ID=11065896

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69526855T Expired - Lifetime DE69526855T2 (de) 1994-03-07 1995-03-06 Krebstest, in welchem eine vom H19-Gen abgeleitete Sonde verwendet wird

Country Status (7)

Country Link
US (1) US5955273A (de)
EP (1) EP0759092B1 (de)
AU (1) AU1893095A (de)
DE (1) DE69526855T2 (de)
ES (1) ES2177653T3 (de)
IL (1) IL108879A (de)
WO (1) WO1995024503A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000510330A (ja) * 1996-04-05 2000-08-15 トーマス・ジェファーソン・ユニバーシティ 癌の診断および予後のための方法
US6087164A (en) * 1997-10-03 2000-07-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods and compositions for inducing tumor-specific cytotoxicity
US7041654B2 (en) 1997-10-03 2006-05-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods and compositions for inducing tumor-specific cytotoxicity
DE19828624C1 (de) * 1998-06-26 2000-02-24 Deutsches Krebsforsch Modular aufgebaute RNA-Moleküle mit zwei Sequenzbereichstypen
US20060121477A1 (en) * 2002-09-12 2006-06-08 Abraham Hochberg Method for detection of micro-metastasis
US7482156B2 (en) * 2003-10-15 2009-01-27 Cell Genesys, Inc. Hepatocellular carcinoma specific promoter and uses thereof
CA2614531C (en) 2005-07-07 2015-06-16 Avraham Hochberg Nucleic acid agents for downregulating h19, and methods of using same
US8034914B2 (en) * 2005-09-22 2011-10-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Nucleic acid constructs, pharmaceutical compositions and methods of using same for treating cancer
WO2008087641A2 (en) * 2007-01-16 2008-07-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem H19 silencing nucleic acid agents for treating rheumatoid arthritis
US20100196403A1 (en) * 2007-01-29 2010-08-05 Jacob Hochman Antibody conjugates for circumventing multi-drug resistance
EP2203187B1 (de) 2007-10-25 2012-08-29 Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. Konstruktionen mit mehreren expressionskassetten für die krebstherapie
WO2016203476A1 (en) 2015-06-18 2016-12-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods and compositions for diagnosing and treating urothelial cancer
WO2018214249A1 (zh) * 2017-05-22 2018-11-29 立森印迹诊断技术（无锡）有限公司 一种印记基因分级模型及其组成的系统和应用
WO2018218737A1 (zh) * 2017-06-01 2018-12-06 立森印迹诊断技术（无锡）有限公司 一种印记基因在膀胱肿瘤中的分级模型及其组成的系统
WO2019041689A1 (zh) * 2017-08-31 2019-03-07 立森印迹诊断技术（无锡）有限公司 用于结直肠肿瘤的印记基因分级模型及其组成的系统
WO2019105381A1 (zh) * 2017-11-28 2019-06-06 立森印迹诊断技术有限公司 一种用于检测乳腺肿瘤良恶性程度的分级模型及其应用
CN110714075A (zh) * 2018-07-13 2020-01-21 立森印迹诊断技术（无锡）有限公司 一种用于检测肺肿瘤良恶性程度的分级模型及其应用
CN110890128B (zh) * 2018-09-10 2024-02-09 立森印迹诊断技术（无锡）有限公司 一种用于检测皮肤肿瘤良恶性程度的分级模型及其应用
CN111172278B (zh) * 2018-11-12 2024-02-09 立森印迹诊断技术（无锡）有限公司 一种用于检测前列腺肿瘤良恶性程度的分级模型及其应用
WO2020103905A1 (zh) * 2018-11-21 2020-05-28 立森印迹诊断技术有限公司 肺癌预后标志物、肺癌预后分型模型及其应用
CN112301125A (zh) * 2019-07-30 2021-02-02 立森印迹诊断技术（无锡）有限公司 一种肿瘤标志物及其应用

Also Published As

Publication number Publication date
US5955273A (en) 1999-09-21
DE69526855T2 (de) 2002-11-28
EP0759092B1 (de) 2002-05-29
EP0759092A1 (de) 1997-02-26
ES2177653T3 (es) 2002-12-16
IL108879A0 (en) 1994-06-24
WO1995024503A1 (en) 1995-09-14
AU1893095A (en) 1995-09-25
IL108879A (en) 2000-08-31

Similar Documents

Publication Publication Date Title
DE69526855T2 (de) Krebstest, in welchem eine vom H19-Gen abgeleitete Sonde verwendet wird
DE69416685T2 (de) Kryochirurgische sonde
DE69109086T2 (de) Kapazitieve sonde.
DE69528187T2 (de) Ultraschall-lipektomie sonde
NO905460L (no) Broennsonde.
DE69026732T2 (de) Sonde
DE69423814D1 (de) Medizinische Sonde
DE69635744D1 (de) Modifizierte Nukleinsäuresonden
DE69518698T2 (de) Zeitanzeiger für eine Zuletzt verabreichte Injektion für einen Injektionsstift
DE69601464T2 (de) Robuste spektroskopische sonde
DE69228369D1 (de) Berührungslose Testsonde
DE69105758D1 (de) Intramuskulaere sonde zum eluiren vom steroid.
DE69029206D1 (de) Verbesserte kapazitive Sonde
DE69020328T2 (de) Kontaktlose profilprüfeinheit.
NL194563B (nl) Digitaliserende oscilloscoop.
DE69405781D1 (de) Testverfahren, das zwei voneinander unterscheidbare partikeltupen verwendet
DE68904334D1 (de) Kapazitive messsonde.
DE9117226U1 (de) Mehrkoordinaten-Tastmeßgerät
DE69216063D1 (de) Tastkopf
NL1000363C2 (nl) Sonde-verbindingsstuk.
DE69007534T2 (de) Ultraschallmikroskopsonde.
FR2710755B1 (fr) Sonde vélocimétrique et clinométrique à laser.
FR2716684B1 (fr) Banc à broches.
DE69717170D1 (de) Pitot-statische sonde
ITBO930481A0 (it) "sonda di tastaggio"

Legal Events

Date Code Title Description
8364 No opposition during term of opposition