DE69528062D1 - Verfahren zum herstellen von emulsionen aus einem emulgator - Google Patents

Verfahren zum herstellen von emulsionen aus einem emulgator

Info

Publication number
DE69528062D1
DE69528062D1 DE69528062T DE69528062T DE69528062D1 DE 69528062 D1 DE69528062 D1 DE 69528062D1 DE 69528062 T DE69528062 T DE 69528062T DE 69528062 T DE69528062 T DE 69528062T DE 69528062 D1 DE69528062 D1 DE 69528062D1
Authority
DE
Germany
Prior art keywords
emulgator
producing emulsions
emulsions
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69528062T
Other languages
English (en)
Other versions
DE69528062T2 (de
Inventor
Akira Saheki
Junzo Seki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shinyaku Co Ltd
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Publication of DE69528062D1 publication Critical patent/DE69528062D1/de
Application granted granted Critical
Publication of DE69528062T2 publication Critical patent/DE69528062T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40Mixing liquids with liquids; Emulsifying
    • B01F23/41Emulsifying
    • B01F23/4105Methods of emulsifying
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/20Jet mixers, i.e. mixers using high-speed fluid streams
    • B01F25/23Mixing by intersecting jets
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/20Jet mixers, i.e. mixers using high-speed fluid streams
    • B01F25/25Mixing by jets impinging against collision plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40Static mixers
    • B01F25/42Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40Static mixers
    • B01F25/42Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B01F25/4331Mixers with bended, curved, coiled, wounded mixing tubes or comprising elements for bending the flow
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40Static mixers
    • B01F25/42Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B01F25/4332Mixers with a strong change of direction in the conduit for homogenizing the flow
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40Static mixers
    • B01F25/42Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B01F25/4334Mixers with a converging cross-section
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40Static mixers
    • B01F25/44Mixers in which the components are pressed through slits
    • B01F25/441Mixers in which the components are pressed through slits characterised by the configuration of the surfaces forming the slits
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40Static mixers
    • B01F25/44Mixers in which the components are pressed through slits
    • B01F25/442Mixers in which the components are pressed through slits characterised by the relative position of the surfaces during operation
    • B01F25/4422Mixers in which the components are pressed through slits characterised by the relative position of the surfaces during operation the surfaces being maintained in a fixed but adjustable position, spaced from each other, therefore allowing the slit spacing to be varied
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S516/00Colloid systems and wetting agents; subcombinations thereof; processes of
    • Y10S516/922Colloid systems having specified particle size, range, or distribution, e.g. bimodal particle distribution
    • Y10S516/923Emulsion
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S516/00Colloid systems and wetting agents; subcombinations thereof; processes of
    • Y10S516/924Significant dispersive or manipulative operation or step in making or stabilizing colloid system
    • Y10S516/928Mixing combined with non-mixing operation or step, successively or simultaneously, e.g. heating, cooling, ph change, ageing, milling
DE69528062T 1994-06-20 1995-06-19 Verfahren zum herstellen von emulsionen aus einem emulgator Expired - Fee Related DE69528062T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP13705494 1994-06-20
PCT/JP1995/001209 WO1995035157A1 (fr) 1994-06-20 1995-06-19 Procede de fabrication d'emulsion et emulsificateur

Publications (2)

Publication Number Publication Date
DE69528062D1 true DE69528062D1 (de) 2002-10-10
DE69528062T2 DE69528062T2 (de) 2003-04-30

Family

ID=15189808

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69528062T Expired - Fee Related DE69528062T2 (de) 1994-06-20 1995-06-19 Verfahren zum herstellen von emulsionen aus einem emulgator

Country Status (4)

Country Link
US (1) US5843334A (de)
EP (1) EP0770422B1 (de)
DE (1) DE69528062T2 (de)
WO (1) WO1995035157A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017085508A1 (en) 2015-11-19 2017-05-26 Sofia University "St. Kliment Ohridski" A method for the preparation of particles with controlled shape and/or size

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5720551A (en) * 1994-10-28 1998-02-24 Shechter; Tal Forming emulsions
SK57199A3 (en) * 1996-10-29 1999-12-10 Unilever Nv Method for the preparation of a foodstuff
US5927852A (en) * 1997-12-01 1999-07-27 Minnesota Mining And Manfacturing Company Process for production of heat sensitive dispersions or emulsions
US6207719B1 (en) * 1998-08-19 2001-03-27 Dennis G. Pardikes Method and system for preparing ASA emulsion
US6106145A (en) * 1999-03-31 2000-08-22 Baker Hughes Incorporated Adjustable homogenizer device
JP4649689B2 (ja) * 1999-07-09 2011-03-16 ダイキン工業株式会社 ポリフルオロアルキルエステル類の製造方法およびこのエステルを用いる含フッ素アクリル共重合体の製造方法
EP1702607B1 (de) * 2004-01-06 2017-04-05 Shiseido Company, Ltd. Monophasische mikroemulsionszusammensetzung, ultrafeine öl-in-wasser-emulsion als topische formulierung und verfahren zu ihrer herstellung
AU2006346369B2 (en) 2005-07-18 2013-02-21 University Of Massachusetts Lowell Compositions and methods for making and using nanoemulsions
WO2008045107A2 (en) 2005-12-01 2008-04-17 University Of Massachusetts Lowell Botulinum nanoemulsions
US9486408B2 (en) 2005-12-01 2016-11-08 University Of Massachusetts Lowell Botulinum nanoemulsions
US20100172943A1 (en) 2006-12-01 2010-07-08 Anterios, Inc. Peptide nanoparticles and uses therefor
CA2671447A1 (en) 2006-12-01 2008-06-12 Anterios, Inc. Amphiphilic entity nanoparticles
CN101765423B (zh) 2007-05-31 2014-08-06 安特里奥公司 核酸纳米粒子和其用途
US9445975B2 (en) 2008-10-03 2016-09-20 Access Business Group International, Llc Composition and method for preparing stable unilamellar liposomal suspension
DE102009056884B4 (de) 2009-12-03 2021-03-18 Novartis Ag Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben
CL2012001399A1 (es) 2009-12-03 2013-03-08 Novartis Ag Metodo para fabricar adyuvante para vacuna (emulsion aceite/agua con escualeno, polisorbato 80 y trioleato de sorbitan), que comprende (i) formar primera emulsion en homogenizador desde un contendor a otro para formar segunda emulsion, (ii) y microfluidizar primera emulsion para formar segunda emulsion.
EP2506832B1 (de) 2009-12-03 2014-02-26 Novartis AG Hydrophile filtrierung bei der herstellung von impfstoffhilfsstoffen
US8895629B2 (en) 2009-12-03 2014-11-25 Novartis Ag Circulation of components during homogenization of emulsions
DE102009056883B4 (de) 2009-12-03 2012-08-16 Novartis Ag Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben
DE102009056871A1 (de) 2009-12-03 2011-06-22 Novartis AG, 4056 Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben
MX340263B (es) 2009-12-03 2016-07-04 Novartis Ag * Disposicion de camaras de interaccion y contrapresion para la microfluidizacion.
ES2764971T3 (es) * 2009-12-22 2020-06-05 Evonik Corp Proceso basado en emulsión para la preparación de micropartículas y conjunto de cabezal de trabajo para su uso con el mismo
JP5801974B1 (ja) * 2015-02-12 2015-10-28 株式会社Nextコロイド分散凝集技術研究所 多層エマルションの製造方法、及びカプセルの製造方法
CN110198703A (zh) 2016-11-21 2019-09-03 艾里奥治疗公司 大试剂的透皮递送

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1817958A (en) * 1926-08-21 1931-08-11 Nat Aniline & Chem Co Inc Dispersion
US3684251A (en) * 1970-09-08 1972-08-15 Us Army Apparatus for continuous emulsification
US4081863A (en) * 1975-07-23 1978-03-28 Gaulin Corporation Method and valve apparatus for homogenizing fluid emulsions and dispersions and controlling homogenizing efficiency and uniformity of processed particles
US4057223A (en) * 1975-10-03 1977-11-08 Nalco Chemical Company Mixing block for mixing polymers
JPS5577035U (de) * 1978-11-16 1980-05-27
CH626788A5 (de) * 1978-11-17 1981-12-15 Nestle Sa
JPS5577035A (en) * 1978-12-01 1980-06-10 Tdk Corp Production of magnetic recording medium
US4383769A (en) * 1980-01-29 1983-05-17 Gaulin Corporation Homogenizing apparatus and method
US4344752A (en) * 1980-03-14 1982-08-17 The Trane Company Water-in-oil emulsifier and oil-burner boiler system incorporating such emulsifier
JPS5926128A (ja) * 1982-08-05 1984-02-10 Konishiroku Photo Ind Co Ltd 分散液滴の製造装置
FR2534487B1 (fr) * 1982-10-15 1988-06-10 Dior Christian Parfums Procede d'homogeneisation de dispersions de phases lamellaires lipidiques hydratees, et suspensions obtenues par ce procede
FR2543018B1 (fr) * 1983-03-22 1985-07-26 Oreal Procede de preparation de vesicules lipidiques par vaporisation de solvants
JPS621444A (ja) * 1985-06-27 1987-01-07 Snow Brand Milk Prod Co Ltd 高圧型均質機
US4664528A (en) * 1985-10-18 1987-05-12 Betz Laboratories, Inc. Apparatus for mixing water and emulsion polymer
CH677886A5 (de) * 1989-06-26 1991-07-15 Hans Georg Prof Dr Weder
US5173007A (en) * 1989-10-23 1992-12-22 Serv-Tech, Inc. Method and apparatus for in-line blending of aqueous emulsion
DE4031094A1 (de) * 1990-10-02 1992-04-09 Basf Ag Verfahren zur herstellung von stabilen injizierbaren (beta)-carotin-solubilisaten
US5149720A (en) * 1991-08-12 1992-09-22 The Procter & Gamble Company Process for preparing emulsions that are polymerizable to absorbent foam materials
US5273407A (en) * 1992-04-30 1993-12-28 Apv Gaulin Gmbh Homogenizing system having improved fluid flow path
US5554382A (en) * 1993-05-28 1996-09-10 Aphios Corporation Methods and apparatus for making liposomes

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017085508A1 (en) 2015-11-19 2017-05-26 Sofia University "St. Kliment Ohridski" A method for the preparation of particles with controlled shape and/or size

Also Published As

Publication number Publication date
WO1995035157A1 (fr) 1995-12-28
EP0770422A1 (de) 1997-05-02
DE69528062T2 (de) 2003-04-30
EP0770422A4 (de) 1998-03-25
US5843334A (en) 1998-12-01
EP0770422B1 (de) 2002-09-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee