DE69532970D1 - Sprühgetrocknetes erythropoietin - Google Patents
Sprühgetrocknetes erythropoietinInfo
- Publication number
- DE69532970D1 DE69532970D1 DE69532970T DE69532970T DE69532970D1 DE 69532970 D1 DE69532970 D1 DE 69532970D1 DE 69532970 T DE69532970 T DE 69532970T DE 69532970 T DE69532970 T DE 69532970T DE 69532970 D1 DE69532970 D1 DE 69532970D1
- Authority
- DE
- Germany
- Prior art keywords
- sprühgetrocknetes
- erythropoietin
- rhepo
- provides
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000003951 Erythropoietin Human genes 0.000 title 1
- 108090000394 Erythropoietin Proteins 0.000 title 1
- 229940105423 erythropoietin Drugs 0.000 title 1
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 title 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000007921 spray Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35794794A | 1994-12-16 | 1994-12-16 | |
US357947 | 1994-12-16 | ||
EP95943452A EP0805822B2 (de) | 1994-12-16 | 1995-12-15 | Sprühgetrocknetes erythropoietin |
PCT/US1995/016416 WO1996018647A1 (en) | 1994-12-16 | 1995-12-15 | Spray dried erythropoietin |
Publications (3)
Publication Number | Publication Date |
---|---|
DE69532970D1 true DE69532970D1 (en) | 2004-06-03 |
DE69532970T2 DE69532970T2 (de) | 2005-06-09 |
DE69532970T3 DE69532970T3 (de) | 2012-02-09 |
Family
ID=23407689
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69532970T Expired - Lifetime DE69532970T3 (de) | 1994-12-16 | 1995-12-15 | Sprühgetrocknetes erythropoietin |
Country Status (19)
Country | Link |
---|---|
US (2) | US6001800A (de) |
EP (1) | EP0805822B2 (de) |
JP (1) | JP4039686B2 (de) |
CN (1) | CN1117762C (de) |
AT (1) | ATE265468T1 (de) |
AU (1) | AU697287B2 (de) |
CA (1) | CA2207615C (de) |
DE (1) | DE69532970T3 (de) |
DK (1) | DK0805822T4 (de) |
ES (1) | ES2219672T5 (de) |
FI (1) | FI119723B (de) |
HU (1) | HU222370B1 (de) |
IL (1) | IL116085A (de) |
NO (1) | NO319895B1 (de) |
NZ (1) | NZ298981A (de) |
PT (1) | PT805822E (de) |
TW (1) | TW425287B (de) |
WO (1) | WO1996018647A1 (de) |
ZA (1) | ZA9510708B (de) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19539574A1 (de) | 1995-10-25 | 1997-04-30 | Boehringer Mannheim Gmbh | Zubereitungen und Verfahren zur Stabilisierung biologischer Materialien mittels Trocknungsverfahren ohne Einfrieren |
US6151332A (en) | 1997-06-20 | 2000-11-21 | Tantivy Communications, Inc. | Protocol conversion and bandwidth reduction technique providing multiple nB+D ISDN basic rate interface links over a wireless code division multiple access communication system |
US6081536A (en) | 1997-06-20 | 2000-06-27 | Tantivy Communications, Inc. | Dynamic bandwidth allocation to transmit a wireless protocol across a code division multiple access (CDMA) radio link |
US6542481B2 (en) | 1998-06-01 | 2003-04-01 | Tantivy Communications, Inc. | Dynamic bandwidth allocation for multiple access communication using session queues |
EP0913177A1 (de) * | 1997-11-03 | 1999-05-06 | Roche Diagnostics GmbH | Verfahren zur Herstellung trockener, amorpher Produkte enthaltend biologisch aktive Materialien mittels Konvektionstrocknung, insbesondere Sprühtrocknung |
US7496072B2 (en) | 1997-12-17 | 2009-02-24 | Interdigital Technology Corporation | System and method for controlling signal strength over a reverse link of a CDMA wireless communication system |
US9525923B2 (en) | 1997-12-17 | 2016-12-20 | Intel Corporation | Multi-detection of heartbeat to reduce error probability |
US6222832B1 (en) | 1998-06-01 | 2001-04-24 | Tantivy Communications, Inc. | Fast Acquisition of traffic channels for a highly variable data rate reverse link of a CDMA wireless communication system |
US7936728B2 (en) | 1997-12-17 | 2011-05-03 | Tantivy Communications, Inc. | System and method for maintaining timing of synchronization messages over a reverse link of a CDMA wireless communication system |
US7394791B2 (en) | 1997-12-17 | 2008-07-01 | Interdigital Technology Corporation | Multi-detection of heartbeat to reduce error probability |
US8134980B2 (en) | 1998-06-01 | 2012-03-13 | Ipr Licensing, Inc. | Transmittal of heartbeat signal at a lower level than heartbeat request |
US7773566B2 (en) | 1998-06-01 | 2010-08-10 | Tantivy Communications, Inc. | System and method for maintaining timing of synchronization messages over a reverse link of a CDMA wireless communication system |
US6526034B1 (en) | 1999-09-21 | 2003-02-25 | Tantivy Communications, Inc. | Dual mode subscriber unit for short range, high rate and long range, lower rate data communications |
WO2001058044A2 (en) | 2000-02-07 | 2001-08-09 | Tantivy Communications, Inc. | Minimal maintenance link to support synchronization |
US8155096B1 (en) | 2000-12-01 | 2012-04-10 | Ipr Licensing Inc. | Antenna control system and method |
US6954448B2 (en) | 2001-02-01 | 2005-10-11 | Ipr Licensing, Inc. | Alternate channel for carrying selected message types |
US7551663B1 (en) | 2001-02-01 | 2009-06-23 | Ipr Licensing, Inc. | Use of correlation combination to achieve channel detection |
EP1471871B1 (de) | 2001-02-02 | 2007-05-02 | Ortho-McNeil Pharmaceutical, Inc. | Behandlung von neurologischen funktionsstörungen mit fructopyranosesulfamaten und erythropoetin |
ES2626289T3 (es) | 2001-06-13 | 2017-07-24 | Intel Corporation | Método y aparatos para la transmisión de señal de latido a un nivel más bajo que la solicitud de latido |
ATE466085T1 (de) * | 2002-09-09 | 2010-05-15 | Hanall Pharmaceutical Co Ltd | Protease-resistente modifizierte interferon alpha polypeptide |
EP1578394A4 (de) * | 2002-12-31 | 2011-02-23 | Nektar Therapeutics | Antikörperhaltige partikel und zusammensetzungen |
EP1683812B1 (de) | 2003-11-14 | 2014-11-12 | Chugai Seiyaku Kabushiki Kaisha | Mikroteilchen aus vernetztem polysaccharid und deren herstellungsverfahren |
EP1836314B1 (de) | 2004-12-22 | 2012-01-25 | Ambrx, Inc. | Modifiziertes menschliches wachstumshormon |
JP5425398B2 (ja) | 2004-12-22 | 2014-02-26 | アンブレツクス・インコーポレイテツド | 非天然アミノ酸及びポリペプチドを含む組成物、非天然アミノ酸及びポリペプチドに関連する方法並び非天然アミノ酸及びポリペプチドその使用 |
US20090018029A1 (en) | 2005-11-16 | 2009-01-15 | Ambrx, Inc. | Methods and Compositions Comprising Non-Natural Amino Acids |
JP5840345B2 (ja) | 2006-09-08 | 2016-01-06 | アンブルックス, インコーポレイテッドAmbrx, Inc. | 修飾ヒト血漿ポリペプチドまたは修飾ヒトFc足場タンパク質ならびにこれらの利用 |
EP2120998B1 (de) | 2006-11-28 | 2013-08-07 | HanAll Biopharma Co., Ltd. | Modifizierte erythropoetin-polypeptide und ihre verwendungen zur behandlung |
KR101476472B1 (ko) | 2007-03-30 | 2015-01-05 | 암브룩스, 인코포레이티드 | 변형된 fgf-21 폴리펩티드 및 그 용도 |
JP2010525821A (ja) | 2007-05-02 | 2010-07-29 | アンブルックス,インコーポレイテッド | 修飾IFNβポリペプチドおよびこれらの使用 |
NZ621174A (en) * | 2008-01-15 | 2015-09-25 | Abbvie Deutschland | Powdered protein compositions and methods of making same |
EP3225248B1 (de) | 2008-07-23 | 2023-06-07 | Ambrx, Inc. | Modifizierte bovine g-csf-polypeptide und ihre verwendung |
PT104350A (pt) | 2009-01-23 | 2010-07-23 | Hovione Farmaci Ncia S A | Processo de isolamento de tigeciclina |
NZ600363A (en) | 2009-12-21 | 2014-07-25 | Ambrx Inc | Modified porcine somatotropin polypeptides and their uses |
EP2805964A1 (de) | 2009-12-21 | 2014-11-26 | Ambrx, Inc. | Modifizierte Rinder-Somatotropinpolypeptide und deren Verwendungen |
TWI480288B (zh) | 2010-09-23 | 2015-04-11 | Lilly Co Eli | 牛顆粒細胞群落刺激因子及其變體之調配物 |
AU2012204462A1 (en) | 2011-01-05 | 2013-07-11 | Hospira, Inc. | Spray drying vancomycin |
WO2013126552A1 (en) | 2012-02-21 | 2013-08-29 | Auburn University | Buprenorphine nanoparticle composition and methods thereof |
CN104043104B (zh) | 2013-03-15 | 2018-07-10 | 浙江创新生物有限公司 | 含盐酸万古霉素的喷雾干粉及其工业化制备方法 |
UY36370A (es) | 2014-10-24 | 2016-04-29 | Bristol Myers Squibb Company Una Corporación Del Estado De Delaware | Polipéptidos fgf-21 modificados y sus usos |
CN104984323B (zh) * | 2015-06-12 | 2018-05-01 | 北京四环生物制药有限公司 | 注射用重组人促红素冻干粉针剂 |
CN105311624A (zh) * | 2015-11-23 | 2016-02-10 | 哈药集团生物工程有限公司 | 一种含有重组人促红素的药物组合物 |
JP7441826B2 (ja) | 2018-09-11 | 2024-03-01 | アンブルックス,インコーポレイテッド | インターロイキン-2ポリペプチド抱合物およびその使用 |
AU2019361206A1 (en) | 2018-10-19 | 2021-06-03 | Ambrx, Inc. | Interleukin-10 polypeptide conjugates, dimers thereof, and their uses |
JP2022520792A (ja) | 2019-02-12 | 2022-04-01 | アンブルックス,インコーポレイテッド | 抗体-tlrアゴニストコンジュゲートを含有する組成物、その方法、及び使用 |
CA3174114A1 (en) | 2020-03-11 | 2021-09-16 | Ambrx, Inc. | Interleukin-2 polypeptide conjugates and methods of use thereof |
JP2023538071A (ja) | 2020-08-20 | 2023-09-06 | アンブルックス,インコーポレイテッド | 抗体-tlrアゴニストコンジュゲート、その方法及び使用 |
CA3213805A1 (en) | 2021-04-03 | 2022-10-06 | Feng Tian | Anti-her2 antibody-drug conjugates and uses thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57149228A (en) * | 1981-03-11 | 1982-09-14 | Ajinomoto Co Inc | Novel erythropoietin and its preparation |
JPS6197229A (ja) * | 1984-10-18 | 1986-05-15 | Chugai Pharmaceut Co Ltd | 安定なエリトロポエチン製剤 |
DE3729863A1 (de) * | 1987-09-05 | 1989-03-16 | Boehringer Mannheim Gmbh | Stabilisierte erythropoietin-lyophilisate |
GB9001987D0 (en) * | 1990-01-29 | 1990-03-28 | Janssen Pharmaceutica Nv | Improved cyclodextrin based erythropietin formulation |
US5354934A (en) * | 1993-02-04 | 1994-10-11 | Amgen Inc. | Pulmonary administration of erythropoietin |
-
1995
- 1995-11-21 IL IL11608595A patent/IL116085A/xx not_active IP Right Cessation
- 1995-12-15 NZ NZ298981A patent/NZ298981A/xx not_active IP Right Cessation
- 1995-12-15 WO PCT/US1995/016416 patent/WO1996018647A1/en active IP Right Grant
- 1995-12-15 ZA ZA9510708A patent/ZA9510708B/xx unknown
- 1995-12-15 DK DK95943452.3T patent/DK0805822T4/da active
- 1995-12-15 HU HU9800996A patent/HU222370B1/hu active IP Right Grant
- 1995-12-15 EP EP95943452A patent/EP0805822B2/de not_active Expired - Lifetime
- 1995-12-15 DE DE69532970T patent/DE69532970T3/de not_active Expired - Lifetime
- 1995-12-15 CA CA2207615A patent/CA2207615C/en not_active Expired - Lifetime
- 1995-12-15 AU AU44713/96A patent/AU697287B2/en not_active Expired
- 1995-12-15 JP JP51929496A patent/JP4039686B2/ja not_active Expired - Lifetime
- 1995-12-15 AT AT95943452T patent/ATE265468T1/de active
- 1995-12-15 PT PT95943452T patent/PT805822E/pt unknown
- 1995-12-15 CN CN95197638.9A patent/CN1117762C/zh not_active Expired - Lifetime
- 1995-12-15 ES ES95943452T patent/ES2219672T5/es not_active Expired - Lifetime
-
1996
- 1996-06-06 TW TW085106816A patent/TW425287B/zh not_active IP Right Cessation
- 1996-12-15 US US08/894,023 patent/US6001800A/en not_active Expired - Lifetime
-
1997
- 1997-06-13 NO NO19972725A patent/NO319895B1/no not_active IP Right Cessation
- 1997-06-16 FI FI972557A patent/FI119723B/fi not_active IP Right Cessation
-
1999
- 1999-10-12 US US09/415,726 patent/US6235710B1/en not_active Expired - Lifetime
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
8328 | Change in the person/name/address of the agent |
Representative=s name: BOEHMERT & BOEHMERT, 28209 BREMEN |
|
R102 | Epo decision maintaining patent in amended form now final |
Ref document number: 805822 Country of ref document: EP Effective date: 20110615 |