DE69535317D1 - Aus nematoden extrahierte serinprotease-inhibitoren und die koagulation hemmende proteine - Google Patents

Aus nematoden extrahierte serinprotease-inhibitoren und die koagulation hemmende proteine

Info

Publication number
DE69535317D1
DE69535317D1 DE69535317T DE69535317T DE69535317D1 DE 69535317 D1 DE69535317 D1 DE 69535317D1 DE 69535317 T DE69535317 T DE 69535317T DE 69535317 T DE69535317 T DE 69535317T DE 69535317 D1 DE69535317 D1 DE 69535317D1
Authority
DE
Germany
Prior art keywords
serine protease
protease inhibitors
coagulation
proteins
inhibiting proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69535317T
Other languages
English (en)
Other versions
DE69535317T2 (de
Inventor
Phillip Vlasuk
Eric Stanssens
Hilda Messens
Josef Lauwereys
Rene Laroche
Stephane Jespers
Georges Gansemans
Matthew Moyle
W Bergum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dendreon Corp
Original Assignee
Dendreon Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/326,110 external-priority patent/US5945275A/en
Priority claimed from US08/465,380 external-priority patent/US5863894A/en
Priority claimed from US08/486,399 external-priority patent/US5866543A/en
Priority claimed from US08/486,397 external-priority patent/US5866542A/en
Priority claimed from US08/461,965 external-priority patent/US5872098A/en
Application filed by Dendreon Corp filed Critical Dendreon Corp
Application granted granted Critical
Publication of DE69535317D1 publication Critical patent/DE69535317D1/de
Publication of DE69535317T2 publication Critical patent/DE69535317T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
DE69535317T 1994-10-18 1995-10-17 Aus nematoden extrahierte serinprotease-inhibitoren und die koagulation hemmende proteine Expired - Lifetime DE69535317T2 (de)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US486399 1990-02-28
US08/326,110 US5945275A (en) 1994-10-18 1994-10-18 Nematode-extracted anticoagulant protein
US326110 1994-10-18
US461965 1995-06-05
US08/465,380 US5863894A (en) 1995-06-05 1995-06-05 Nematode-extracted anticoagulant protein
US08/486,399 US5866543A (en) 1995-06-05 1995-06-05 Nematode-extracted anticoagulant protein
US486397 1995-06-05
US465380 1995-06-05
US08/486,397 US5866542A (en) 1994-10-18 1995-06-05 Nematode-extracted anticoagulant protein
US08/461,965 US5872098A (en) 1995-06-05 1995-06-05 Nematode-extracted anticoagulant protein
PCT/US1995/013231 WO1996012021A2 (en) 1994-10-18 1995-10-17 Nematode-extracted serine protease inhibitors and anticoagulant proteins

Publications (2)

Publication Number Publication Date
DE69535317D1 true DE69535317D1 (de) 2007-01-11
DE69535317T2 DE69535317T2 (de) 2007-06-21

Family

ID=27541063

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69535317T Expired - Lifetime DE69535317T2 (de) 1994-10-18 1995-10-17 Aus nematoden extrahierte serinprotease-inhibitoren und die koagulation hemmende proteine

Country Status (12)

Country Link
US (11) US6090916A (de)
EP (2) EP0788546B9 (de)
JP (3) JP3811186B2 (de)
AT (1) ATE346928T1 (de)
AU (1) AU711405B2 (de)
DE (1) DE69535317T2 (de)
DK (1) DK0788546T3 (de)
ES (1) ES2276396T3 (de)
HU (1) HU225126B1 (de)
NZ (1) NZ296648A (de)
PL (1) PL183855B1 (de)
WO (1) WO1996012021A2 (de)

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KR102169651B1 (ko) 2011-01-06 2020-10-23 다이액스 코포레이션 혈장 칼리크레인 결합 단백질
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Also Published As

Publication number Publication date
ATE346928T1 (de) 2006-12-15
JP4101833B2 (ja) 2008-06-18
HUT77431A (hu) 1998-04-28
US6096877A (en) 2000-08-01
JP2006117675A (ja) 2006-05-11
US6046318A (en) 2000-04-04
US6872808B1 (en) 2005-03-29
DE69535317T2 (de) 2007-06-21
PL319782A1 (en) 1997-08-18
WO1996012021A3 (en) 1996-07-25
EP0788546B9 (de) 2007-06-13
AU4130796A (en) 1996-05-06
WO1996012021A2 (en) 1996-04-25
EP1772516A1 (de) 2007-04-11
HU225126B1 (en) 2006-06-28
US6534629B1 (en) 2003-03-18
US6087487A (en) 2000-07-11
US20060246547A1 (en) 2006-11-02
DK0788546T3 (da) 2007-04-10
EP0788546B1 (de) 2006-11-29
EP0788546A1 (de) 1997-08-13
ES2276396T3 (es) 2007-06-16
US6090916A (en) 2000-07-18
AU711405B2 (en) 1999-10-14
US6040441A (en) 2000-03-21
NZ296648A (en) 2001-05-25
US20100240584A1 (en) 2010-09-23
JP3811186B2 (ja) 2006-08-16
US20050191724A1 (en) 2005-09-01
JPH10507361A (ja) 1998-07-21
US6121435A (en) 2000-09-19
PL183855B1 (pl) 2002-07-31
JP2007145851A (ja) 2007-06-14

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