DE69610227T2 - Verfahren zur selektiver trennung organischer komponenten aus biologischen flüssigkeiten - Google Patents
Verfahren zur selektiver trennung organischer komponenten aus biologischen flüssigkeitenInfo
- Publication number
- DE69610227T2 DE69610227T2 DE69610227T DE69610227T DE69610227T2 DE 69610227 T2 DE69610227 T2 DE 69610227T2 DE 69610227 T DE69610227 T DE 69610227T DE 69610227 T DE69610227 T DE 69610227T DE 69610227 T2 DE69610227 T2 DE 69610227T2
- Authority
- DE
- Germany
- Prior art keywords
- blood
- organic components
- selective separation
- invention pertains
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/644—Coagulation factor IXa (3.4.21.22)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21022—Coagulation factor IXa (3.4.21.22)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2154596P | 1996-07-10 | 1996-07-10 | |
PCT/US1996/020034 WO1998001464A1 (en) | 1996-07-10 | 1996-12-20 | Methods for the selective separation of organic components from biological fluids |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69610227D1 DE69610227D1 (de) | 2000-10-12 |
DE69610227T2 true DE69610227T2 (de) | 2001-01-04 |
Family
ID=21804845
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69610227T Expired - Lifetime DE69610227T2 (de) | 1996-07-10 | 1996-12-20 | Verfahren zur selektiver trennung organischer komponenten aus biologischen flüssigkeiten |
Country Status (8)
Country | Link |
---|---|
US (1) | US6193891B1 (de) |
EP (1) | EP0915906B1 (de) |
AT (1) | ATE196148T1 (de) |
AU (1) | AU1422597A (de) |
DE (1) | DE69610227T2 (de) |
DK (1) | DK0915906T3 (de) |
ES (1) | ES2149515T3 (de) |
WO (1) | WO1998001464A1 (de) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPN030794A0 (en) | 1994-12-22 | 1995-01-27 | Aruba International Pty Ltd | Discontinuous plasma or serum delipidation |
JP4856833B2 (ja) * | 1999-12-22 | 2012-01-18 | メルク・シャープ・エンド・ドーム・コーポレイション | プラスミドdnaの大規模化可能な精製方法 |
US20020012990A1 (en) * | 1999-12-22 | 2002-01-31 | Lander Russel Jackson | Process for the scaleable purification of plasmid DNA |
US8597516B2 (en) * | 2000-05-16 | 2013-12-03 | Immunocept, L.L.C. | Methods and systems for colloid exchange therapy |
US7407662B2 (en) * | 2000-06-29 | 2008-08-05 | Lipid Sciences, Inc. | Modified viral particles with immunogenic properties and reduced lipid content |
AUPQ846900A0 (en) * | 2000-06-29 | 2000-07-27 | Aruba International Pty Ltd | A vaccine |
US7439052B2 (en) * | 2000-06-29 | 2008-10-21 | Lipid Sciences | Method of making modified immunodeficiency virus particles |
US7407663B2 (en) * | 2000-06-29 | 2008-08-05 | Lipid Sciences, Inc. | Modified immunodeficiency virus particles |
US20090017069A1 (en) * | 2000-06-29 | 2009-01-15 | Lipid Sciences, Inc. | SARS Vaccine Compositions and Methods of Making and Using Them |
US20020164825A1 (en) * | 2000-09-09 | 2002-11-07 | Wen-Tien Chen | Cell separation matrix |
US6506308B1 (en) * | 2000-09-12 | 2003-01-14 | Advanced Minerals Corporation | Methods for the removal of organic substances from aqueous solutions |
WO2002092161A1 (en) * | 2001-05-10 | 2002-11-21 | Biophan, Llc | Miniaturized particle analyzer |
EP1409108A4 (de) * | 2001-06-25 | 2007-11-14 | Lipid Sciences Inc | Hohlfaserberührungssysteme zur entfernung von lipiden aus fluiden |
AU2002322284A1 (en) * | 2001-06-25 | 2003-01-08 | Lipid Sciences, Inc. | Systems and methods using multiple solvents for the removal of lipids from fluids |
EP1412045A4 (de) * | 2001-06-25 | 2007-05-02 | Lipid Sciences Inc | Ein lösungsmittel zur entfernung von lipiden aus fluiden verwendende systeme und verfahren |
US6991727B2 (en) * | 2001-06-25 | 2006-01-31 | Lipid Sciences, Inc. | Hollow fiber contactor systems for removal of lipids from fluids |
US20060060520A1 (en) * | 2001-06-25 | 2006-03-23 | Bomberger David C | Systems and methods using a solvent for the removal of lipids from fluids |
WO2003035888A1 (en) * | 2001-08-28 | 2003-05-01 | Wen-Tien Chen | Cell separation matrix |
CA2462244C (en) * | 2001-10-04 | 2010-11-09 | Toray Industries, Inc. | A hydrophilic substance and a production method thereof |
US20030201229A1 (en) * | 2002-02-04 | 2003-10-30 | Martin Siwak | Process for prefiltration of a protein solution |
WO2003066669A2 (en) * | 2002-02-04 | 2003-08-14 | Millipore Corporation | Process for removing protein aggregates and virus from a protein solution |
US20040106556A1 (en) * | 2002-08-26 | 2004-06-03 | Yanhong Zhu | Method of treating and preventing alzheimer disease through administration of delipidated protein and lipoprotein particles |
WO2004072647A1 (en) * | 2003-02-07 | 2004-08-26 | Beyond Genomics | Removal of proteins from a sample |
US20040245144A1 (en) * | 2003-06-03 | 2004-12-09 | Hurst William E. | Preformed mixing bag for dry powder, apparatus, method and system for using same |
US20040245124A1 (en) * | 2003-06-03 | 2004-12-09 | Hurst William E. | Preformed mixing bag for dry powder, apparatus, method and system for using same |
PT2368565E (pt) * | 2003-07-03 | 2015-10-19 | Hdl Therapeutics Inc | Enriquecimento de lipoproteínas pré-beta de alta densidade |
US7393826B2 (en) * | 2003-07-03 | 2008-07-01 | Lipid Sciences, Inc. | Methods and apparatus for creating particle derivatives of HDL with reduced lipid content |
US6960803B2 (en) * | 2003-10-23 | 2005-11-01 | Silicon Storage Technology, Inc. | Landing pad for use as a contact to a conductive spacer |
FR2869995B1 (fr) * | 2004-05-10 | 2006-09-22 | Sebia Sa | Procede ameliore de separation de proteines par electrophorese capillaire et compositions de tampon pour electrophorese capillaire |
US20080028989A1 (en) * | 2006-07-20 | 2008-02-07 | Scott Kevin Palm | Process for removing organic contaminants from non-metallic inorganic materials using dielectric heating |
US20080119350A1 (en) * | 2006-11-20 | 2008-05-22 | Korea Institute Of Geosciences And Mineral Resources | Ion exchange type lithium adsorbent using filter and method for preparing the same |
US8835104B2 (en) | 2007-12-20 | 2014-09-16 | Fenwal, Inc. | Medium and methods for the storage of platelets |
KR101839278B1 (ko) * | 2007-12-28 | 2018-03-15 | 박스알타 인코퍼레이티드 | 단백질의 역압 여과 |
EP2652491B1 (de) | 2010-12-15 | 2017-11-29 | Baxalta GmbH | Eluatsammlung mit leitfähigkeitsgradient |
AU2012240016B2 (en) | 2011-04-07 | 2016-11-10 | Fenwal, Inc. | Automated methods and systems for providing platelet concentrates with reduced residual plasma volumes and storage media for such platelet concentrates |
KR101446265B1 (ko) * | 2011-10-17 | 2014-11-03 | 메디칸(주) | 면역성이 제거된 생체지방소재 및 이의 제조방법 |
DE102014210662A1 (de) | 2014-06-04 | 2015-12-17 | Gea Westfalia Separator Group Gmbh | Vorrichtung und Verfahren zur Gewinnung von Glycoglycerolipiden und Glycosphingolipiden aus lipoiden Phasen |
CN105153297B (zh) * | 2015-09-17 | 2020-03-31 | 中国人民解放军军事医学科学院野战输血研究所 | 一种从Cohn组分Ⅳ沉淀中分离纯化α2-巨球蛋白的方法 |
WO2017066683A1 (en) * | 2015-10-15 | 2017-04-20 | Plasma Technologies, Llc | Methods for extracting proteins from blood plasma |
CA3083194A1 (en) | 2017-11-22 | 2019-05-31 | Hdl Therapeutics, Inc. | Systems and methods for priming fluid circuits of a plasma processing system |
CA3087207A1 (en) | 2017-12-28 | 2019-07-04 | Hdl Therapeutics, Inc. | Methods for preserving and administering pre-beta high density lipoprotein extracted from human plasma |
US11471497B1 (en) | 2019-03-13 | 2022-10-18 | David Gordon Bermudes | Copper chelation therapeutics |
CN115066497A (zh) * | 2019-12-03 | 2022-09-16 | 奥姆里克斯生物药品有限公司 | 凝血酶原纯化 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2539397A (en) | 1947-03-26 | 1951-01-30 | Nat Cylinder Gas Co | Purification of sugar solutions |
US3099626A (en) | 1958-12-31 | 1963-07-30 | Johns Manville | Sweetener for dry cleaners' solvents |
DE2239254C2 (de) * | 1970-12-30 | 1983-08-04 | Organon Teknika Corp., Oklahoma City, Okla. | "Säule zur Regenerierung einer zirkulierenden Dialysatlösung und Verwendung dieser Säule". |
JPS5327491A (en) * | 1976-08-26 | 1978-03-14 | Terumo Corp | Separation and refining process for red corpuscle |
US4112129A (en) * | 1977-09-14 | 1978-09-05 | Johns-Manville Corporation | Cooking oil treating system and composition therefor |
JPS5545458A (en) * | 1978-09-29 | 1980-03-31 | Kyowa Kagaku Kogyo Kk | Adsorbent for purifying blood |
US4399164A (en) | 1979-01-26 | 1983-08-16 | Nutrisearch Company | Preparation of a dried blend of whey by-product and casein or its salts |
US4384954A (en) * | 1980-04-16 | 1983-05-24 | Kuraray Co., Ltd. | Column for adsorption of blood proteins |
JPS5810056A (ja) * | 1981-07-10 | 1983-01-20 | 株式会社クラレ | 血液浄化装置 |
FR2561074B1 (fr) | 1984-03-15 | 1986-10-31 | Lille I Universite Sciences Te | Procede de decoloration de substances colorees par des composes tetrapyrroliques, et produits obtenus |
US5037649A (en) * | 1985-01-11 | 1991-08-06 | Imre Corporation | Method for treatment of HIV-infected patients |
CA1259915A (en) * | 1985-10-09 | 1989-09-26 | Sailen S. Mookerjea | Means to reduce plasma cholesterol |
US5252762A (en) | 1991-04-03 | 1993-10-12 | W. R. Grace & Co.-Conn. | Use of base-treated inorganic porous adsorbents for removal of contaminants |
ES2087831B1 (es) | 1994-12-22 | 1997-04-01 | Tolsa Sa | Nueva litera absorbente a base de sepiolita para animales y procedimiento para su preparacion. |
US6008040A (en) * | 1995-07-07 | 1999-12-28 | Synosys, Inc. | Procedures for efficient separation of cells, cellular materials and proteins |
-
1996
- 1996-12-20 AT AT96944412T patent/ATE196148T1/de active
- 1996-12-20 AU AU14225/97A patent/AU1422597A/en not_active Abandoned
- 1996-12-20 WO PCT/US1996/020034 patent/WO1998001464A1/en active IP Right Grant
- 1996-12-20 DE DE69610227T patent/DE69610227T2/de not_active Expired - Lifetime
- 1996-12-20 ES ES96944412T patent/ES2149515T3/es not_active Expired - Lifetime
- 1996-12-20 DK DK96944412T patent/DK0915906T3/da active
- 1996-12-20 EP EP96944412A patent/EP0915906B1/de not_active Expired - Lifetime
- 1996-12-20 US US08/765,101 patent/US6193891B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO1998001464A1 (en) | 1998-01-15 |
DK0915906T3 (da) | 2000-11-20 |
AU1422597A (en) | 1998-02-02 |
EP0915906B1 (de) | 2000-09-06 |
EP0915906A1 (de) | 1999-05-19 |
US6193891B1 (en) | 2001-02-27 |
ES2149515T3 (es) | 2000-11-01 |
DE69610227D1 (de) | 2000-10-12 |
ATE196148T1 (de) | 2000-09-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |