DE69610227T2 - Verfahren zur selektiver trennung organischer komponenten aus biologischen flüssigkeiten - Google Patents

Verfahren zur selektiver trennung organischer komponenten aus biologischen flüssigkeiten

Info

Publication number
DE69610227T2
DE69610227T2 DE69610227T DE69610227T DE69610227T2 DE 69610227 T2 DE69610227 T2 DE 69610227T2 DE 69610227 T DE69610227 T DE 69610227T DE 69610227 T DE69610227 T DE 69610227T DE 69610227 T2 DE69610227 T2 DE 69610227T2
Authority
DE
Germany
Prior art keywords
blood
organic components
selective separation
invention pertains
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69610227T
Other languages
English (en)
Other versions
DE69610227D1 (de
Inventor
S Kent
N Drohan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
American National Red Cross
Original Assignee
American National Red Cross
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American National Red Cross filed Critical American National Red Cross
Application granted granted Critical
Publication of DE69610227D1 publication Critical patent/DE69610227D1/de
Publication of DE69610227T2 publication Critical patent/DE69610227T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/644Coagulation factor IXa (3.4.21.22)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/16Blood plasma; Blood serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21022Coagulation factor IXa (3.4.21.22)
DE69610227T 1996-07-10 1996-12-20 Verfahren zur selektiver trennung organischer komponenten aus biologischen flüssigkeiten Expired - Lifetime DE69610227T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2154596P 1996-07-10 1996-07-10
PCT/US1996/020034 WO1998001464A1 (en) 1996-07-10 1996-12-20 Methods for the selective separation of organic components from biological fluids

Publications (2)

Publication Number Publication Date
DE69610227D1 DE69610227D1 (de) 2000-10-12
DE69610227T2 true DE69610227T2 (de) 2001-01-04

Family

ID=21804845

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69610227T Expired - Lifetime DE69610227T2 (de) 1996-07-10 1996-12-20 Verfahren zur selektiver trennung organischer komponenten aus biologischen flüssigkeiten

Country Status (8)

Country Link
US (1) US6193891B1 (de)
EP (1) EP0915906B1 (de)
AT (1) ATE196148T1 (de)
AU (1) AU1422597A (de)
DE (1) DE69610227T2 (de)
DK (1) DK0915906T3 (de)
ES (1) ES2149515T3 (de)
WO (1) WO1998001464A1 (de)

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US20020012990A1 (en) * 1999-12-22 2002-01-31 Lander Russel Jackson Process for the scaleable purification of plasmid DNA
US8597516B2 (en) * 2000-05-16 2013-12-03 Immunocept, L.L.C. Methods and systems for colloid exchange therapy
US7407662B2 (en) * 2000-06-29 2008-08-05 Lipid Sciences, Inc. Modified viral particles with immunogenic properties and reduced lipid content
AUPQ846900A0 (en) * 2000-06-29 2000-07-27 Aruba International Pty Ltd A vaccine
US7439052B2 (en) * 2000-06-29 2008-10-21 Lipid Sciences Method of making modified immunodeficiency virus particles
US7407663B2 (en) * 2000-06-29 2008-08-05 Lipid Sciences, Inc. Modified immunodeficiency virus particles
US20090017069A1 (en) * 2000-06-29 2009-01-15 Lipid Sciences, Inc. SARS Vaccine Compositions and Methods of Making and Using Them
US20020164825A1 (en) * 2000-09-09 2002-11-07 Wen-Tien Chen Cell separation matrix
US6506308B1 (en) * 2000-09-12 2003-01-14 Advanced Minerals Corporation Methods for the removal of organic substances from aqueous solutions
WO2002092161A1 (en) * 2001-05-10 2002-11-21 Biophan, Llc Miniaturized particle analyzer
EP1409108A4 (de) * 2001-06-25 2007-11-14 Lipid Sciences Inc Hohlfaserberührungssysteme zur entfernung von lipiden aus fluiden
AU2002322284A1 (en) * 2001-06-25 2003-01-08 Lipid Sciences, Inc. Systems and methods using multiple solvents for the removal of lipids from fluids
EP1412045A4 (de) * 2001-06-25 2007-05-02 Lipid Sciences Inc Ein lösungsmittel zur entfernung von lipiden aus fluiden verwendende systeme und verfahren
US6991727B2 (en) * 2001-06-25 2006-01-31 Lipid Sciences, Inc. Hollow fiber contactor systems for removal of lipids from fluids
US20060060520A1 (en) * 2001-06-25 2006-03-23 Bomberger David C Systems and methods using a solvent for the removal of lipids from fluids
WO2003035888A1 (en) * 2001-08-28 2003-05-01 Wen-Tien Chen Cell separation matrix
CA2462244C (en) * 2001-10-04 2010-11-09 Toray Industries, Inc. A hydrophilic substance and a production method thereof
US20030201229A1 (en) * 2002-02-04 2003-10-30 Martin Siwak Process for prefiltration of a protein solution
WO2003066669A2 (en) * 2002-02-04 2003-08-14 Millipore Corporation Process for removing protein aggregates and virus from a protein solution
US20040106556A1 (en) * 2002-08-26 2004-06-03 Yanhong Zhu Method of treating and preventing alzheimer disease through administration of delipidated protein and lipoprotein particles
WO2004072647A1 (en) * 2003-02-07 2004-08-26 Beyond Genomics Removal of proteins from a sample
US20040245144A1 (en) * 2003-06-03 2004-12-09 Hurst William E. Preformed mixing bag for dry powder, apparatus, method and system for using same
US20040245124A1 (en) * 2003-06-03 2004-12-09 Hurst William E. Preformed mixing bag for dry powder, apparatus, method and system for using same
PT2368565E (pt) * 2003-07-03 2015-10-19 Hdl Therapeutics Inc Enriquecimento de lipoproteínas pré-beta de alta densidade
US7393826B2 (en) * 2003-07-03 2008-07-01 Lipid Sciences, Inc. Methods and apparatus for creating particle derivatives of HDL with reduced lipid content
US6960803B2 (en) * 2003-10-23 2005-11-01 Silicon Storage Technology, Inc. Landing pad for use as a contact to a conductive spacer
FR2869995B1 (fr) * 2004-05-10 2006-09-22 Sebia Sa Procede ameliore de separation de proteines par electrophorese capillaire et compositions de tampon pour electrophorese capillaire
US20080028989A1 (en) * 2006-07-20 2008-02-07 Scott Kevin Palm Process for removing organic contaminants from non-metallic inorganic materials using dielectric heating
US20080119350A1 (en) * 2006-11-20 2008-05-22 Korea Institute Of Geosciences And Mineral Resources Ion exchange type lithium adsorbent using filter and method for preparing the same
US8835104B2 (en) 2007-12-20 2014-09-16 Fenwal, Inc. Medium and methods for the storage of platelets
KR101839278B1 (ko) * 2007-12-28 2018-03-15 박스알타 인코퍼레이티드 단백질의 역압 여과
EP2652491B1 (de) 2010-12-15 2017-11-29 Baxalta GmbH Eluatsammlung mit leitfähigkeitsgradient
AU2012240016B2 (en) 2011-04-07 2016-11-10 Fenwal, Inc. Automated methods and systems for providing platelet concentrates with reduced residual plasma volumes and storage media for such platelet concentrates
KR101446265B1 (ko) * 2011-10-17 2014-11-03 메디칸(주) 면역성이 제거된 생체지방소재 및 이의 제조방법
DE102014210662A1 (de) 2014-06-04 2015-12-17 Gea Westfalia Separator Group Gmbh Vorrichtung und Verfahren zur Gewinnung von Glycoglycerolipiden und Glycosphingolipiden aus lipoiden Phasen
CN105153297B (zh) * 2015-09-17 2020-03-31 中国人民解放军军事医学科学院野战输血研究所 一种从Cohn组分Ⅳ沉淀中分离纯化α2-巨球蛋白的方法
WO2017066683A1 (en) * 2015-10-15 2017-04-20 Plasma Technologies, Llc Methods for extracting proteins from blood plasma
CA3083194A1 (en) 2017-11-22 2019-05-31 Hdl Therapeutics, Inc. Systems and methods for priming fluid circuits of a plasma processing system
CA3087207A1 (en) 2017-12-28 2019-07-04 Hdl Therapeutics, Inc. Methods for preserving and administering pre-beta high density lipoprotein extracted from human plasma
US11471497B1 (en) 2019-03-13 2022-10-18 David Gordon Bermudes Copper chelation therapeutics
CN115066497A (zh) * 2019-12-03 2022-09-16 奥姆里克斯生物药品有限公司 凝血酶原纯化

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US6008040A (en) * 1995-07-07 1999-12-28 Synosys, Inc. Procedures for efficient separation of cells, cellular materials and proteins

Also Published As

Publication number Publication date
WO1998001464A1 (en) 1998-01-15
DK0915906T3 (da) 2000-11-20
AU1422597A (en) 1998-02-02
EP0915906B1 (de) 2000-09-06
EP0915906A1 (de) 1999-05-19
US6193891B1 (en) 2001-02-27
ES2149515T3 (es) 2000-11-01
DE69610227D1 (de) 2000-10-12
ATE196148T1 (de) 2000-09-15

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