DE69621015D1 - Gasemulsionen, die durch fluorierte ether mit niedrigen ostwaldkoeffizienten stabilisiert sind - Google Patents
Gasemulsionen, die durch fluorierte ether mit niedrigen ostwaldkoeffizienten stabilisiert sindInfo
- Publication number
- DE69621015D1 DE69621015D1 DE69621015T DE69621015T DE69621015D1 DE 69621015 D1 DE69621015 D1 DE 69621015D1 DE 69621015 T DE69621015 T DE 69621015T DE 69621015 T DE69621015 T DE 69621015T DE 69621015 D1 DE69621015 D1 DE 69621015D1
- Authority
- DE
- Germany
- Prior art keywords
- gas emulsions
- ocf2
- emulsions stabilized
- 2ocf3
- fluorine ethers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000839 emulsion Substances 0.000 title abstract 3
- -1 FLUORINE ETHERS Chemical class 0.000 title 1
- 229910052731 fluorine Inorganic materials 0.000 title 1
- 239000011737 fluorine Substances 0.000 title 1
- XZKOELJOFVHXRS-UHFFFAOYSA-N 1,1,1,2,2,3,3-heptafluoro-3-(1,1,2,2,3,3,3-heptafluoropropoxy)propane Chemical compound FC(F)(F)C(F)(F)C(F)(F)OC(F)(F)C(F)(F)C(F)(F)F XZKOELJOFVHXRS-UHFFFAOYSA-N 0.000 abstract 1
- JTPMOHUDFCBCEC-UHFFFAOYSA-N 1,1,2,2-tetrafluoro-1,2-bis(trifluoromethoxy)ethane Chemical compound FC(F)(F)OC(F)(F)C(F)(F)OC(F)(F)F JTPMOHUDFCBCEC-UHFFFAOYSA-N 0.000 abstract 1
- YSGKVOMJRCQYMT-UHFFFAOYSA-N 1,1,2,2-tetrafluoro-1-[1,1,2,2-tetrafluoro-2-(trifluoromethoxy)ethoxy]-2-(trifluoromethoxy)ethane Chemical compound FC(F)(F)OC(F)(F)C(F)(F)OC(F)(F)C(F)(F)OC(F)(F)F YSGKVOMJRCQYMT-UHFFFAOYSA-N 0.000 abstract 1
- 229920001774 Perfluoroether Polymers 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000005923 long-lasting effect Effects 0.000 abstract 1
- 238000002595 magnetic resonance imaging Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000012285 ultrasound imaging Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1806—Suspensions, emulsions, colloids, dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/226—Solutes, emulsions, suspensions, dispersions, semi-solid forms, e.g. hydrogels
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/479,621 US5804162A (en) | 1995-06-07 | 1995-06-07 | Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients |
| PCT/US1996/009068 WO1996040281A2 (en) | 1995-06-07 | 1996-06-05 | Gas emulsions stabilized with fluorinated ethers having low ostwald coefficients |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69621015D1 true DE69621015D1 (de) | 2002-06-06 |
| DE69621015T2 DE69621015T2 (de) | 2002-12-19 |
Family
ID=23904745
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69636486T Expired - Fee Related DE69636486T2 (de) | 1995-06-07 | 1996-06-05 | Gasemulsionen, die durch fluorierte Ether mit niedrigen Ostwaldkoeffizienten stabilisiert sind |
| DE69621015T Expired - Fee Related DE69621015T2 (de) | 1995-06-07 | 1996-06-05 | Gasemulsionen, die durch fluorierte ether mit niedrigen ostwaldkoeffizienten stabilisiert sind |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69636486T Expired - Fee Related DE69636486T2 (de) | 1995-06-07 | 1996-06-05 | Gasemulsionen, die durch fluorierte Ether mit niedrigen Ostwaldkoeffizienten stabilisiert sind |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US5804162A (de) |
| EP (2) | EP1174153B1 (de) |
| JP (1) | JP4067116B2 (de) |
| KR (1) | KR100401429B1 (de) |
| CN (1) | CN1087954C (de) |
| AT (2) | ATE337018T1 (de) |
| AU (1) | AU712946B2 (de) |
| CA (1) | CA2222186A1 (de) |
| CZ (1) | CZ391397A3 (de) |
| DE (2) | DE69636486T2 (de) |
| DK (1) | DK0833669T3 (de) |
| ES (2) | ES2269262T3 (de) |
| HU (1) | HUP9900848A3 (de) |
| IL (1) | IL122217A (de) |
| NO (1) | NO975317L (de) |
| PL (1) | PL185883B1 (de) |
| PT (1) | PT833669E (de) |
| WO (1) | WO1996040281A2 (de) |
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-
1995
- 1995-06-07 US US08/479,621 patent/US5804162A/en not_active Expired - Fee Related
-
1996
- 1996-06-05 ES ES01119824T patent/ES2269262T3/es not_active Expired - Lifetime
- 1996-06-05 US US08/973,281 patent/US6193952B1/en not_active Expired - Fee Related
- 1996-06-05 PT PT96918164T patent/PT833669E/pt unknown
- 1996-06-05 AT AT01119824T patent/ATE337018T1/de not_active IP Right Cessation
- 1996-06-05 EP EP01119824A patent/EP1174153B1/de not_active Expired - Lifetime
- 1996-06-05 JP JP50147797A patent/JP4067116B2/ja not_active Expired - Fee Related
- 1996-06-05 AT AT96918164T patent/ATE216894T1/de not_active IP Right Cessation
- 1996-06-05 PL PL96323868A patent/PL185883B1/pl unknown
- 1996-06-05 EP EP96918164A patent/EP0833669B1/de not_active Expired - Lifetime
- 1996-06-05 HU HU9900848A patent/HUP9900848A3/hu unknown
- 1996-06-05 ES ES96918164T patent/ES2176462T3/es not_active Expired - Lifetime
- 1996-06-05 CN CN96195879A patent/CN1087954C/zh not_active Expired - Fee Related
- 1996-06-05 CA CA002222186A patent/CA2222186A1/en not_active Abandoned
- 1996-06-05 KR KR1019970709075A patent/KR100401429B1/ko not_active IP Right Cessation
- 1996-06-05 DE DE69636486T patent/DE69636486T2/de not_active Expired - Fee Related
- 1996-06-05 WO PCT/US1996/009068 patent/WO1996040281A2/en not_active Application Discontinuation
- 1996-06-05 CZ CZ973913A patent/CZ391397A3/cs unknown
- 1996-06-05 AU AU60487/96A patent/AU712946B2/en not_active Ceased
- 1996-06-05 DE DE69621015T patent/DE69621015T2/de not_active Expired - Fee Related
- 1996-06-05 IL IL12221796A patent/IL122217A/en not_active IP Right Cessation
- 1996-06-05 DK DK96918164T patent/DK0833669T3/da active
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1997
- 1997-11-19 NO NO975317A patent/NO975317L/no not_active Application Discontinuation
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