DE69637047D1 - Unabhängiges gerät zur extraktion, amplifikation und nachweis von nukleinsäuren - Google Patents
Unabhängiges gerät zur extraktion, amplifikation und nachweis von nukleinsäurenInfo
- Publication number
- DE69637047D1 DE69637047D1 DE69637047T DE69637047T DE69637047D1 DE 69637047 D1 DE69637047 D1 DE 69637047D1 DE 69637047 T DE69637047 T DE 69637047T DE 69637047 T DE69637047 T DE 69637047T DE 69637047 D1 DE69637047 D1 DE 69637047D1
- Authority
- DE
- Germany
- Prior art keywords
- detection
- extraction
- amplification
- nucleic acid
- nucleic acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5082—Test tubes per se
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
- B01L2300/047—Additional chamber, reservoir
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0663—Whole sensors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
- B01L2400/0644—Valves, specific forms thereof with moving parts rotary valves
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/81—Tube, bottle, or dipstick
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US88595P | 1995-07-13 | 1995-07-13 | |
US885P | 1995-07-13 | ||
PCT/US1996/011633 WO1997003348A1 (en) | 1995-07-13 | 1996-07-12 | Self-contained device integrating nucleic acid extraction, amplification and detection |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69637047D1 true DE69637047D1 (de) | 2007-06-06 |
DE69637047T2 DE69637047T2 (de) | 2007-12-27 |
Family
ID=21693436
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69637047T Expired - Lifetime DE69637047T2 (de) | 1995-07-13 | 1996-07-12 | Unabhängiges gerät zur extraktion, amplifikation und nachweis von nukleinsäuren |
Country Status (8)
Country | Link |
---|---|
US (1) | US5955351A (de) |
EP (1) | EP0838025B1 (de) |
JP (1) | JPH11509100A (de) |
AT (1) | ATE360808T1 (de) |
AU (1) | AU718183B2 (de) |
CA (1) | CA2226717A1 (de) |
DE (1) | DE69637047T2 (de) |
WO (1) | WO1997003348A1 (de) |
Families Citing this family (87)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110097791A1 (en) * | 1999-04-16 | 2011-04-28 | Engelhardt Dean L | Novel process, construct and conjugate for producing multiple nucleic acid copies |
US20050123926A1 (en) * | 1994-01-13 | 2005-06-09 | Enzo Diagnostics, Inc., | In vitro process for producing multiple nucleic acid copies |
US6986985B1 (en) * | 1994-01-13 | 2006-01-17 | Enzo Life Sciences, Inc. | Process for producing multiple nucleic acid copies in vivo using a protein-nucleic acid construct |
US6153425A (en) * | 1995-07-13 | 2000-11-28 | Xtrana, Inc. | Self-contained device integrating nucleic acid extraction, amplification and detection |
US5989499A (en) * | 1997-05-02 | 1999-11-23 | Biomerieux, Inc. | Dual chamber disposable reaction vessel for amplification reactions |
US6429007B1 (en) | 1997-05-02 | 2002-08-06 | BIOMéRIEUX, INC. | Nucleic acid amplification reaction station for disposable test devices |
US6410275B1 (en) | 1997-05-02 | 2002-06-25 | Biomerieux, Inc. | Disposable test devices for performing nucleic acid amplification reactions |
DE69831830T2 (de) * | 1997-06-09 | 2006-06-22 | F. Hoffmann-La Roche Ag | Einweg-Analysevorrichtung |
EP1179585B1 (de) | 1997-12-24 | 2008-07-09 | Cepheid | Vorrichtung und Verfahren zur Lyse |
US8337753B2 (en) | 1998-05-01 | 2012-12-25 | Gen-Probe Incorporated | Temperature-controlled incubator having a receptacle mixing mechanism |
DE1075328T1 (de) | 1998-05-01 | 2001-10-11 | Ammann Kelly G | Automatische diagnostische analysevorrichtung und -verfahren |
US6413780B1 (en) * | 1998-10-14 | 2002-07-02 | Abbott Laboratories | Structure and method for performing a determination of an item of interest in a sample |
DK1121460T3 (da) * | 1998-10-23 | 2010-09-20 | Qiagen Ges Mit Beschraenkter H | Fremgangsmåde og middel til isolering og oprensning af nucleinsyrer på overflader |
US6887693B2 (en) | 1998-12-24 | 2005-05-03 | Cepheid | Device and method for lysing cells, spores, or microorganisms |
US7914994B2 (en) * | 1998-12-24 | 2011-03-29 | Cepheid | Method for separating an analyte from a sample |
US6818185B1 (en) | 1999-05-28 | 2004-11-16 | Cepheid | Cartridge for conducting a chemical reaction |
US8815521B2 (en) | 2000-05-30 | 2014-08-26 | Cepheid | Apparatus and method for cell disruption |
US9073053B2 (en) * | 1999-05-28 | 2015-07-07 | Cepheid | Apparatus and method for cell disruption |
CA2374423C (en) * | 1999-05-28 | 2013-04-09 | Cepheid | Apparatus and method for analyzing a liquid sample |
US6159727A (en) * | 1999-06-04 | 2000-12-12 | Clontech Laboratories, Inc. | Hybridization chamber |
WO2000077253A1 (fr) * | 1999-06-16 | 2000-12-21 | Hitachi, Ltd. | Appareil et procede d'examen des genes |
DE19963032A1 (de) | 1999-12-24 | 2001-06-28 | Roche Diagnostics Gmbh | System zur Bearbeitung von Proben in einer Mehrkammeranordnung |
DE10006214A1 (de) | 2000-02-11 | 2001-08-16 | Roche Diagnostics Gmbh | System zur einfachen Nukleinsäureanalytik |
WO2001070402A2 (en) * | 2000-03-22 | 2001-09-27 | Dewalch Technologies, Inc. | Method and apparatus for processing substances in a single container |
US20080260593A1 (en) * | 2000-03-22 | 2008-10-23 | Dewalch Norman Binz | Method and apparatus for processing substances in a single container |
US6869532B2 (en) * | 2001-06-04 | 2005-03-22 | Cuno Incorporated | Nucleic acid binding matrix |
US20030098271A1 (en) * | 2001-11-26 | 2003-05-29 | Ralph Somack | Capsule and tray systems for combined sample collection, archiving, purification, and PCR |
US20040014097A1 (en) * | 2002-05-06 | 2004-01-22 | Mcglennen Ronald C. | Genetic test apparatus and method |
AU2003260679A1 (en) * | 2002-07-12 | 2004-02-02 | British Biocell International Limited | Lateral flow assay device and method |
US8594948B2 (en) * | 2002-09-18 | 2013-11-26 | Ronald C. McGlennen | Apparatus and methods for medical testing |
US20060278242A1 (en) * | 2005-03-23 | 2006-12-14 | Mcglennen Ronald C | Apparatus and methods for medical testing |
US7217542B2 (en) * | 2002-10-31 | 2007-05-15 | Hewlett-Packard Development Company, L.P. | Microfluidic system for analyzing nucleic acids |
WO2004048936A2 (en) * | 2002-11-26 | 2004-06-10 | University Of Utah Research Foundation | Microporous materials, methods, and articles for localizing and quantifying analytes |
US7597936B2 (en) * | 2002-11-26 | 2009-10-06 | University Of Utah Research Foundation | Method of producing a pigmented composite microporous material |
DE102004021822B3 (de) * | 2004-04-30 | 2005-11-17 | Siemens Ag | Verfahren und Anordnung zur DNA-Amplifikation mittels PCR unter Einsatz von Trockenreagenzien |
DE102004021780B4 (de) * | 2004-04-30 | 2008-10-02 | Siemens Ag | Verfahren und Anordnung zur DNA-Isolierung mit Trockenreagenzien |
US20060264714A1 (en) * | 2005-03-23 | 2006-11-23 | Mcglennen Ronald C | Apparatus and methods for medical testing |
GB0604973D0 (en) * | 2006-03-11 | 2006-04-19 | Central Science Lab Csl Of San | Purification method and kit |
US11001881B2 (en) | 2006-08-24 | 2021-05-11 | California Institute Of Technology | Methods for detecting analytes |
US11525156B2 (en) | 2006-07-28 | 2022-12-13 | California Institute Of Technology | Multiplex Q-PCR arrays |
US9839909B2 (en) | 2006-07-28 | 2017-12-12 | Diagnostics For The Real World, Ltd. | Device, system and method for processing a sample |
US8048626B2 (en) | 2006-07-28 | 2011-11-01 | California Institute Of Technology | Multiplex Q-PCR arrays |
CN1888902B (zh) * | 2006-08-11 | 2011-05-18 | 杭州优思达生物技术有限公司 | 全封闭式靶核酸扩增物快速检测装置 |
US11560588B2 (en) | 2006-08-24 | 2023-01-24 | California Institute Of Technology | Multiplex Q-PCR arrays |
US7492312B2 (en) * | 2006-11-14 | 2009-02-17 | Fam Adly T | Multiplicative mismatched filters for optimum range sidelobe suppression in barker code reception |
GB0701253D0 (en) | 2007-01-23 | 2007-02-28 | Diagnostics For The Real World | Nucleic acid amplification and testing |
CA2691451C (en) | 2007-06-21 | 2015-03-24 | Sara H. Fan | Instrument and receptacles for performing processes |
DE102007029772B4 (de) * | 2007-06-22 | 2011-12-08 | Aj Innuscreen Gmbh | Verfahren und Schnelltest zum Nachweis spezifischer Nukleinsäuresequenzen |
IL184183A0 (en) * | 2007-06-25 | 2007-10-31 | Benjamin Alspector | Bi directional transfer of an aliquot of fluid between compartments |
WO2009024773A1 (en) | 2007-08-17 | 2009-02-26 | Diagnostics For The Real World, Ltd | Device, system and method for processing a sample |
US8415141B2 (en) * | 2007-08-17 | 2013-04-09 | Qimin You | Enclosed unit for rapid detection of a target nucleic acid amplification product |
JP5628677B2 (ja) | 2007-10-19 | 2014-11-19 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | ベータ−ラクタマーゼの検出のための方法および組成物 |
US9409166B2 (en) * | 2007-12-10 | 2016-08-09 | The Trustees Of The University Of Pennsylvania | Integrated PCR reactor for cell lysis, nucleic acid isolation and purification, and nucleic acid amplication related applications |
EP2257646A1 (de) | 2008-02-29 | 2010-12-08 | ISIS Innovation Limited | Diagnoseverfahren |
US9817001B2 (en) | 2008-05-27 | 2017-11-14 | Boston Heart Diagnostics Corporation | Methods for determining LDL cholesterol treatment |
US8470541B1 (en) * | 2008-09-27 | 2013-06-25 | Boston Heart Diagnostics Corporation | Methods for separation and immuno-detection of biomolecules, and apparatus related thereto |
WO2010047778A1 (en) * | 2008-10-20 | 2010-04-29 | Becton Dickinson And Company | Compositions for the detection of intracellular bacterial targets and other intracellular microorganism targets |
WO2010075025A2 (en) * | 2008-12-16 | 2010-07-01 | Shell Oil Company | Device for evaluating a heat exchange fluid |
US9121054B2 (en) * | 2009-12-08 | 2015-09-01 | Biohelix Corporation | Detection of nucleic acid amplification products in the presence of an internal control sequence on an immunochromatographic strip |
CN103540518B (zh) | 2010-07-23 | 2015-07-08 | 贝克曼考尔特公司 | 化验盒 |
WO2012063877A1 (ja) * | 2010-11-09 | 2012-05-18 | 株式会社ジェイ・エム・エス | 分離容器および分離方法 |
EP2766728B1 (de) | 2011-10-13 | 2017-09-06 | Boston Heart Diagnostics | Zusammensetzungen und verfahren zur behandlung und prävention von koronarer herzkrankheit |
CN104053997B (zh) | 2011-11-07 | 2016-12-21 | 贝克曼考尔特公司 | 用于处理样本的系统和方法 |
WO2013070754A1 (en) | 2011-11-07 | 2013-05-16 | Beckman Coulter, Inc. | Robotic arm |
BR112014011046A2 (pt) | 2011-11-07 | 2017-06-13 | Beckman Coulter, Inc. | fluxo de trabalho e sistema de centrífuga |
WO2013070740A1 (en) | 2011-11-07 | 2013-05-16 | Beckman Coulter, Inc. | Aliquotter system and workflow |
KR20140091033A (ko) | 2011-11-07 | 2014-07-18 | 베크만 컬터, 인코포레이티드 | 검체 컨테이너 검출 |
US8973736B2 (en) | 2011-11-07 | 2015-03-10 | Beckman Coulter, Inc. | Magnetic damping for specimen transport system |
AU2013203281A1 (en) | 2012-02-03 | 2013-08-22 | Axxin Pty Ltd | Nucleic acid amplification and detection apparatus and method |
EP2864503B1 (de) * | 2012-06-26 | 2019-10-09 | Axxin Pty Ltd | Nukleinsäureamplifikations- und -nachweiskit |
JP6166938B2 (ja) * | 2013-04-18 | 2017-07-19 | ローム株式会社 | マイクロチップ |
US9828624B2 (en) | 2013-07-24 | 2017-11-28 | Boston Heart Diagnostics Corporation | Driving patient compliance with therapy |
WO2015187849A2 (en) | 2014-06-04 | 2015-12-10 | Lucigen Corporation | Sample collection and analysis devices |
US9593368B2 (en) | 2014-07-01 | 2017-03-14 | General Electric Company | Methods for amplifying nucleic acids on substrates |
US10870845B2 (en) | 2014-07-01 | 2020-12-22 | Global Life Sciences Solutions Operations UK Ltd | Methods for capturing nucleic acids |
US10472620B2 (en) | 2014-07-01 | 2019-11-12 | General Electric Company | Method, substrate and device for separating nucleic acids |
US10463290B2 (en) | 2014-11-14 | 2019-11-05 | Axxin Pty Ltd. | Biological sample collection and storage assembly |
WO2016081471A1 (en) | 2014-11-17 | 2016-05-26 | Boston Heart Diagnostic Corporation | Cardiovascular disease risk assessment |
US11198122B2 (en) | 2015-07-17 | 2021-12-14 | Axxin Pty Ltd | Diagnostic test assembly, apparatus, method |
WO2017117666A1 (en) * | 2016-01-08 | 2017-07-13 | Advanced Theranostics Inc. | Fully integrated, stand-alone, point-of-care device to detect target nucleic acids |
WO2017155858A1 (en) | 2016-03-07 | 2017-09-14 | Insilixa, Inc. | Nucleic acid sequence identification using solid-phase cyclic single base extension |
KR102628173B1 (ko) | 2017-04-19 | 2024-01-25 | 야마토 에슬론 가부시키가이샤 | Pcr용 용기, 시약이 든 pcr용 용기, 및 시약 카세트 |
JP7276716B2 (ja) | 2017-09-27 | 2023-05-18 | アックスイン ピーティーワイ リミテッド | 診断テストシステムおよび方法 |
JP2022513079A (ja) * | 2018-11-19 | 2022-02-07 | バイオカルティス エン フェー | 統合ワークフローでの低コピー数の核酸の強化された検出 |
EP3937780A4 (de) | 2019-03-14 | 2022-12-07 | InSilixa, Inc. | Verfahren und systeme zur zeitgesteuerten fluoreszenzbasierten detektion |
EP4228813A1 (de) * | 2020-10-26 | 2023-08-23 | NAVARRO, Thierry | Vorrichtung und verfahren zur rna- oder dna-amplifikation |
CN113249214B (zh) * | 2021-07-05 | 2022-05-10 | 广州和实生物技术有限公司 | 一种可家庭自测的核酸检测装置、其使用方法及用途 |
Family Cites Families (36)
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US3715189A (en) * | 1970-06-15 | 1973-02-06 | Secretary Of The Treasury | Qualitative analysis device |
US4473530A (en) * | 1980-09-24 | 1984-09-25 | Villa Real Antony Euclid C | Compact sanitary urinalysis unit |
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US4458020A (en) * | 1982-11-15 | 1984-07-03 | Quidel | Integrated single tube plunger immunoassay system having plural reagent chambers |
US4687732A (en) * | 1983-06-10 | 1987-08-18 | Yale University | Visualization polymers and their application to diagnostic medicine |
DE3431536A1 (de) * | 1984-08-28 | 1986-03-13 | Boehringer Mannheim Gmbh, 6800 Mannheim | Derivatisierte nucleinsaeure-sequenz, verfahren zu deren herstellung sowie deren verwendung zum nachweis von nucleinsaeuren |
US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
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US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
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SE465086B (sv) * | 1990-05-16 | 1991-07-22 | Mats Malmquist | Reagenskapillaerer, reaktionskaerl, beredningssaett och anvaendning daerav |
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DE19512369A1 (de) * | 1995-04-01 | 1996-10-02 | Boehringer Mannheim Gmbh | Vorrichtung zur Isolierung von Nukleinsäuren |
-
1996
- 1996-07-12 WO PCT/US1996/011633 patent/WO1997003348A1/en active IP Right Grant
- 1996-07-12 US US08/679,522 patent/US5955351A/en not_active Expired - Lifetime
- 1996-07-12 AT AT96923760T patent/ATE360808T1/de not_active IP Right Cessation
- 1996-07-12 DE DE69637047T patent/DE69637047T2/de not_active Expired - Lifetime
- 1996-07-12 EP EP96923760A patent/EP0838025B1/de not_active Expired - Lifetime
- 1996-07-12 CA CA002226717A patent/CA2226717A1/en not_active Abandoned
- 1996-07-12 JP JP9506006A patent/JPH11509100A/ja not_active Ceased
- 1996-07-12 AU AU64580/96A patent/AU718183B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
AU718183B2 (en) | 2000-04-06 |
AU6458096A (en) | 1997-02-10 |
US5955351A (en) | 1999-09-21 |
JPH11509100A (ja) | 1999-08-17 |
WO1997003348A1 (en) | 1997-01-30 |
EP0838025A1 (de) | 1998-04-29 |
CA2226717A1 (en) | 1997-01-30 |
EP0838025B1 (de) | 2007-04-25 |
ATE360808T1 (de) | 2007-05-15 |
DE69637047T2 (de) | 2007-12-27 |
EP0838025A4 (de) | 1999-10-06 |
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