DE69637150D1 - Für das Beta-A4 (1-42) Peptid spezifischer monoklonaler Antikörper - Google Patents
Für das Beta-A4 (1-42) Peptid spezifischer monoklonaler AntikörperInfo
- Publication number
- DE69637150D1 DE69637150D1 DE69637150T DE69637150T DE69637150D1 DE 69637150 D1 DE69637150 D1 DE 69637150D1 DE 69637150 T DE69637150 T DE 69637150T DE 69637150 T DE69637150 T DE 69637150T DE 69637150 D1 DE69637150 D1 DE 69637150D1
- Authority
- DE
- Germany
- Prior art keywords
- instant invention
- monoclonal antibody
- beta
- specific monoclonal
- peptide specific
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US388463 | 1995-02-14 | ||
US08/388,463 US5786180A (en) | 1995-02-14 | 1995-02-14 | Monoclonal antibody 369.2B specific for β A4 peptide |
EP01114005A EP1160256B2 (de) | 1995-02-14 | 1996-02-14 | Für das Beta-A4 (1-42) Peptid spezifischer monoklonaler Antikörper |
Publications (3)
Publication Number | Publication Date |
---|---|
DE69637150D1 true DE69637150D1 (de) | 2007-08-09 |
DE69637150T2 DE69637150T2 (de) | 2008-02-28 |
DE69637150T3 DE69637150T3 (de) | 2012-03-15 |
Family
ID=23534218
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69637150T Expired - Lifetime DE69637150T3 (de) | 1995-02-14 | 1996-02-14 | Für das Beta-A4 (1-42) Peptid spezifischer monoklonaler Antikörper |
DE69617916T Expired - Fee Related DE69617916T2 (de) | 1995-02-14 | 1996-02-14 | Beta-a4 peptid spezifischer monoklonaler antikörper |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69617916T Expired - Fee Related DE69617916T2 (de) | 1995-02-14 | 1996-02-14 | Beta-a4 peptid spezifischer monoklonaler antikörper |
Country Status (11)
Country | Link |
---|---|
US (3) | US5786180A (de) |
EP (3) | EP1842859B1 (de) |
JP (1) | JP3115606B2 (de) |
AT (2) | ATE210681T1 (de) |
CA (1) | CA2212887C (de) |
DE (2) | DE69637150T3 (de) |
DK (2) | DK1160256T4 (de) |
ES (3) | ES2400674T3 (de) |
HK (1) | HK1114105A1 (de) |
PT (2) | PT1160256E (de) |
WO (1) | WO1996025435A1 (de) |
Families Citing this family (101)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6114133A (en) * | 1994-11-14 | 2000-09-05 | Elan Pharmaceuticals, Inc. | Methods for aiding in the diagnosis of Alzheimer's disease by measuring amyloid-β peptide (x-≧41) |
US7427392B1 (en) | 1994-11-14 | 2008-09-23 | Elan Pharmaceuticals, Inc. | Methods for aiding in the diagnosis of alzheimer's disease by measuring amyloid-β peptide (x-≧41) and tau |
US20060178302A1 (en) * | 1997-02-05 | 2006-08-10 | Northwestern University & The University Of Southern California | Amyloid beta protein (globular assembly and uses thereof) |
US20030068316A1 (en) * | 1997-02-05 | 2003-04-10 | Klein William L. | Anti-ADDL antibodies and uses thereof |
US8173127B2 (en) * | 1997-04-09 | 2012-05-08 | Intellect Neurosciences, Inc. | Specific antibodies to amyloid beta peptide, pharmaceutical compositions and methods of use thereof |
AU743827B2 (en) | 1997-04-09 | 2002-02-07 | Intellect Neurosciences, Inc. | Recombinant antibodies specific for beta-amyloid ends, DNA encoding and methods of use thereof |
ES2136535B1 (es) * | 1997-04-15 | 2000-08-16 | Consejo Superior Investigacion | Peptido sintetico para la produccion de anticuerpos contra el peptido beta amiloide 1-42. |
AU740445B2 (en) * | 1997-04-16 | 2001-11-01 | Wyeth | Beta-amyloid peptide-binding proteins and polynucleotides encoding the same |
US7005295B1 (en) | 1997-04-16 | 2006-02-28 | Wyeth | β-amyloid peptide-binding proteins and polynucleotides encoding the same |
US6787319B2 (en) | 1997-04-16 | 2004-09-07 | American Home Products Corp. | β-amyloid peptide-binding proteins and polynucleotides encoding the same |
US6787523B1 (en) | 1997-12-02 | 2004-09-07 | Neuralab Limited | Prevention and treatment of amyloidogenic disease |
US7179892B2 (en) * | 2000-12-06 | 2007-02-20 | Neuralab Limited | Humanized antibodies that recognize beta amyloid peptide |
US7964192B1 (en) | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
US6710226B1 (en) | 1997-12-02 | 2004-03-23 | Neuralab Limited | Transgenic mouse assay to determine the effect of Aβ antibodies and Aβ Fragments on alzheimer's disease characteristics |
US6743427B1 (en) | 1997-12-02 | 2004-06-01 | Neuralab Limited | Prevention and treatment of amyloidogenic disease |
US20080050367A1 (en) | 1998-04-07 | 2008-02-28 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
US6761888B1 (en) * | 2000-05-26 | 2004-07-13 | Neuralab Limited | Passive immunization treatment of Alzheimer's disease |
US7790856B2 (en) | 1998-04-07 | 2010-09-07 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize beta amyloid peptide |
TWI239847B (en) * | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
US6913745B1 (en) | 1997-12-02 | 2005-07-05 | Neuralab Limited | Passive immunization of Alzheimer's disease |
US7588766B1 (en) | 2000-05-26 | 2009-09-15 | Elan Pharma International Limited | Treatment of amyloidogenic disease |
US6750324B1 (en) | 1997-12-02 | 2004-06-15 | Neuralab Limited | Humanized and chimeric N-terminal amyloid beta-antibodies |
US6923964B1 (en) | 1997-12-02 | 2005-08-02 | Neuralab Limited | Active immunization of AScr for prion disorders |
AU2003262458B2 (en) * | 1998-05-21 | 2008-06-19 | University Of Tennessee Research Foundation | Methods for amyloid removal using anti-amyloid antibodies |
US20030147882A1 (en) * | 1998-05-21 | 2003-08-07 | Alan Solomon | Methods for amyloid removal using anti-amyloid antibodies |
CN1344275A (zh) | 1998-05-21 | 2002-04-10 | 田纳西州立大学研究股份有限公司 | 用淀粉样蛋白抗体除去淀粉样蛋白的方法 |
US6787637B1 (en) | 1999-05-28 | 2004-09-07 | Neuralab Limited | N-Terminal amyloid-β antibodies |
UA81216C2 (en) * | 1999-06-01 | 2007-12-25 | Prevention and treatment of amyloid disease | |
JP5249482B2 (ja) * | 1999-06-16 | 2013-07-31 | ボストン・バイオメデイカル・リサーチ・インステイテユート | インビボのβ−アミロイドレベルの免疫学的制御 |
SI1481992T1 (sl) | 2000-02-24 | 2017-01-31 | Washington University St. Louis | Humanizirana protitelesa, ki vežejo amiloidni peptid beta |
US7485616B2 (en) * | 2000-04-05 | 2009-02-03 | University Of Tennessee Research Foundation | Methods of investigating, diagnosing, and treating amyloidosis |
JP2003516929A (ja) * | 2000-06-01 | 2003-05-20 | ニユーララブ・リミテツド | アミロイド形成性疾患の予防および治療 |
WO2002003911A2 (en) | 2000-07-07 | 2002-01-17 | Lars Lannfelt | Prevention and treatment of alzheimer's disease |
TWI255272B (en) | 2000-12-06 | 2006-05-21 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
US7700751B2 (en) | 2000-12-06 | 2010-04-20 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize β-amyloid peptide |
US6815175B2 (en) * | 2001-03-16 | 2004-11-09 | Cornell Research Foundation, Inc. | Anti-amyloid peptide antibody based diagnosis and treatment of a neurological disease or disorder |
WO2002088307A2 (en) | 2001-04-30 | 2002-11-07 | Eli Lilly And Company | Humanized antibodies |
US7318923B2 (en) | 2001-04-30 | 2008-01-15 | Eli Lilly And Company | Humanized anti-βantibodies |
EP1944040B1 (de) | 2001-08-17 | 2012-08-01 | Washington University | Assay-Verfahren für Alzheimer |
EP1481245A4 (de) * | 2002-03-01 | 2007-06-13 | Applera Corp | Bestimmung der kompatibilität eines satzes chemischer modifikationen mit einer aminosäurekette |
MY139983A (en) * | 2002-03-12 | 2009-11-30 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
US20040107871A1 (en) * | 2002-08-09 | 2004-06-10 | Defeo Maureen A. | Aluminum trihydrate containing slurries |
AU2003279216A1 (en) * | 2002-10-09 | 2004-05-04 | Rinat Neuroscience Corp. | Methods of treating alzheimer's disease using antibodies directed against amyloid beta peptide and compositions thereof |
DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
US20060188512A1 (en) * | 2003-02-01 | 2006-08-24 | Ted Yednock | Active immunization to generate antibodies to solble a-beta |
ES2344645T3 (es) | 2003-02-10 | 2010-09-02 | Applied Molecular Evolution, Inc. | Moleculas de union al abeta. |
US8663650B2 (en) | 2003-02-21 | 2014-03-04 | Ac Immune Sa | Methods and compositions comprising supramolecular constructs |
US7732162B2 (en) | 2003-05-05 | 2010-06-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases |
TWI306458B (en) | 2003-05-30 | 2009-02-21 | Elan Pharma Int Ltd | Humanized antibodies that recognize beta amyloid peptide |
US7807171B2 (en) | 2003-07-25 | 2010-10-05 | Ac Immune Sa | Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers |
SE0401601D0 (sv) | 2004-06-21 | 2004-06-21 | Bioarctic Neuroscience Ab | Protofibril specific antibodies and uses thereof |
TWI355389B (en) * | 2004-07-30 | 2012-01-01 | Rinat Neuroscience Corp | Antibodies directed against amyloid-beta peptide a |
AU2005297854A1 (en) * | 2004-10-28 | 2006-05-04 | Sanko Junyaku Co., Ltd. | Method of examining Alzheimer's disease and diagnostic reagent |
CA2587487A1 (en) * | 2004-11-12 | 2006-05-18 | Pfizer, Inc. | Method of measuring amyloid-beta peptides |
ES2396555T3 (es) | 2004-12-15 | 2013-02-22 | Janssen Alzheimer Immunotherapy | Anticuerpos que reconocen péptido beta amiloide |
PE20061329A1 (es) | 2004-12-15 | 2006-12-08 | Neuralab Ltd | Anticuerpos ab humanizados para mejorar la cognicion |
WO2006081171A1 (en) | 2005-01-24 | 2006-08-03 | Amgen Inc. | Humanized anti-amyloid antibody |
GT200600031A (es) * | 2005-01-28 | 2006-08-29 | Formulacion anticuerpo anti a beta | |
PE20061201A1 (es) * | 2005-01-28 | 2006-11-03 | Wyeth Corp | Formulaciones liquidas estabilizadas de polipeptido |
UY29504A1 (es) | 2005-04-29 | 2006-10-31 | Rinat Neuroscience Corp | Anticuerpos dirigidos contra el péptido amiloide beta y métodos que utilizan los mismos. |
EA201100177A1 (ru) * | 2005-06-17 | 2011-06-30 | Элан Фарма Интернэшнл Лимитед | СПОСОБЫ ОЧИСТКИ АНТИТЕЛ К β-АМИЛОИДУ |
RU2008120027A (ru) * | 2005-10-21 | 2009-11-27 | Мерк энд Ко., Инк. (US) | Анти-addl моноклональное антитело и его применение |
RS53270B2 (sr) | 2005-11-30 | 2018-05-31 | Abbvie Deutschland | Monoklonalna antitela protiv amiloidnog beta proteina i njihova upotreba |
AU2006319358B2 (en) | 2005-11-30 | 2012-01-19 | AbbVie Deutschland GmbH & Co. KG | Anti-Abeta globulomer antibodies, antigen-binding moieties thereof, corresponding hybridomas, nucleic acids, vectors, host cells, methods of producing said antibodies, compositions comprising said antibodies, uses of said antibodies and methods of using said antibodies |
NO345996B1 (no) * | 2005-12-12 | 2021-12-13 | Ac Immune Sa | A beta 1-42-spesifikke monoklonale antistoffer med terapeutiske egenskaper. |
WO2007108756A1 (en) | 2006-03-23 | 2007-09-27 | Bioarctic Neuroscience Ab | Improved protofibril selective antibodies and the use thereof |
US8784810B2 (en) | 2006-04-18 | 2014-07-22 | Janssen Alzheimer Immunotherapy | Treatment of amyloidogenic diseases |
PL2468770T3 (pl) * | 2006-07-14 | 2018-07-31 | Ac Immune S.A. | Humanizowane przeciwciało przeciw amyloidowi beta |
FR2903999B1 (fr) * | 2006-07-19 | 2008-09-05 | Galderma Res & Dev S N C Snc | Modulateurs de sc4mol dans le traitement de l'acne ou de l'hyperseborrhee |
WO2008045962A2 (en) * | 2006-10-10 | 2008-04-17 | Mayo Foundation For Medical Education And Research | Methods and materials related to anti-a (beta) antibodies |
US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
EP2121754B1 (de) | 2007-01-18 | 2015-02-11 | Eli Lilly and Company | Pegyliertes amyloid beta fab |
EP2486928A1 (de) | 2007-02-27 | 2012-08-15 | Abbott GmbH & Co. KG | Verfahren zur Behandlung von Amyloidosen |
AU2008220785B2 (en) | 2007-03-01 | 2013-02-21 | Vivoryon Therapeutics N.V. | New use of glutaminyl cyclase inhibitors |
US9656991B2 (en) | 2007-04-18 | 2017-05-23 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
US8003097B2 (en) | 2007-04-18 | 2011-08-23 | Janssen Alzheimer Immunotherapy | Treatment of cerebral amyloid angiopathy |
US8048420B2 (en) | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
EP2009445A1 (de) * | 2007-06-29 | 2008-12-31 | Institut Pasteur | Verwendung von Einzeldomänen-Camelid-Antikörpern zur Entdeckung einer oligomeren Form eines Amyloid-Betapeptids und deren Anwendungen |
ES2498040T3 (es) | 2007-07-27 | 2014-09-24 | Janssen Alzheimer Immunotherapy | Tratamiento de enfermedades amiloidogénicas con anticuerpos anti-beta humanizados |
US20100297012A1 (en) * | 2007-10-05 | 2010-11-25 | Andrea Pfeifer | Humanized antibody |
ES2445590T3 (es) * | 2007-10-05 | 2014-03-04 | Genentech, Inc. | Uso de anticuerpo anti-amiloide beta en enfermedades oculares |
JO3076B1 (ar) | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | نظم العلاج المناعي المعتمد على حالة apoe |
US9067981B1 (en) | 2008-10-30 | 2015-06-30 | Janssen Sciences Ireland Uc | Hybrid amyloid-beta antibodies |
EP2475428B1 (de) | 2009-09-11 | 2015-07-01 | Probiodrug AG | Heterocyclische derivate als glutaminylcyclase-hemmer |
JP6026284B2 (ja) | 2010-03-03 | 2016-11-16 | プロビオドルグ エージー | グルタミニルシクラーゼの阻害剤 |
JP5688745B2 (ja) | 2010-03-10 | 2015-03-25 | プロビオドルグ エージー | グルタミニルシクラーゼ(qc、ec2.3.2.5)の複素環阻害剤 |
MX336196B (es) | 2010-04-15 | 2016-01-11 | Abbvie Inc | Proteinas de union a amiloide beta. |
US8541596B2 (en) | 2010-04-21 | 2013-09-24 | Probiodrug Ag | Inhibitors |
BR112013002297A2 (pt) | 2010-07-30 | 2016-05-24 | Ac Immune Sa | anticorpos humanizados seguros e funcionais |
EP3527220A1 (de) | 2010-08-12 | 2019-08-21 | AC Immune S.A. | Manipulation von impfstoffen |
WO2012024187A1 (en) | 2010-08-14 | 2012-02-23 | Abbott Laboratories | Amyloid-beta binding proteins |
EP2632434A1 (de) | 2010-10-26 | 2013-09-04 | AC Immune S.A. | Konstrukt auf liposomenbasis mit einem anhand von hydrophoben einheiten modifizierten peptid |
WO2012123563A1 (en) | 2011-03-16 | 2012-09-20 | Probiodrug Ag | Benz imidazole derivatives as inhibitors of glutaminyl cyclase |
WO2012142301A2 (en) | 2011-04-12 | 2012-10-18 | Quanterix Corporation | Methods of determining a treatment protocol for and/or a prognosis of a patients recovery from a brain injury |
JP2012102131A (ja) * | 2012-01-05 | 2012-05-31 | Elan Pharma Internatl Ltd | アミロイド形成性疾患の予防および治療 |
CN103665113A (zh) * | 2012-09-14 | 2014-03-26 | 深圳市安群生物工程有限公司 | 人Aβ42抗原决定簇多肽、抗原、抗体、用途及试剂盒 |
KR102450670B1 (ko) | 2012-10-15 | 2022-10-04 | 메디뮨 리미티드 | 아밀로이드 베타에 대한 항체 |
JP2016103980A (ja) * | 2013-03-08 | 2016-06-09 | パナソニックヘルスケア株式会社 | ハイブリドーマ及びモノクローナル抗体 |
BR112016030774A2 (pt) | 2014-07-10 | 2018-01-16 | Bioarctic Neuroscience Ab | anticorpo ou fragmento de ligação a antígeno do mesmo, uso de um anticorpo, métodos para redução da quantidade de protofibrilas de ?? em um indivíduo, para tratamento e/ou para profilaxia de uma doença, para medição da quantidade de protofibrilas de ?? e/ou de proteína ?? agregada em uma pessoa, e para diagnóstico de uma doença, e, composição farmacêutica |
ES2812698T3 (es) | 2017-09-29 | 2021-03-18 | Probiodrug Ag | Inhibidores de glutaminil ciclasa |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4666829A (en) * | 1985-05-15 | 1987-05-19 | University Of California | Polypeptide marker for Alzheimer's disease and its use for diagnosis |
EP0527823A1 (de) * | 1990-04-24 | 1993-02-24 | The Regents Of The University Of California | Reinigung, nachweis und verfahren zur verwendung der protease-nexin-2 |
US5750349A (en) * | 1993-01-25 | 1998-05-12 | Takeda Chemical Industries Ltd. | Antibodies to β-amyloids or their derivatives and use thereof |
-
1995
- 1995-02-14 US US08/388,463 patent/US5786180A/en not_active Expired - Fee Related
- 1995-06-07 US US08/484,969 patent/US5679531A/en not_active Expired - Lifetime
- 1995-06-07 US US08/472,627 patent/US5693753A/en not_active Expired - Lifetime
-
1996
- 1996-02-14 DE DE69637150T patent/DE69637150T3/de not_active Expired - Lifetime
- 1996-02-14 EP EP07012421A patent/EP1842859B1/de not_active Expired - Lifetime
- 1996-02-14 AT AT96906616T patent/ATE210681T1/de not_active IP Right Cessation
- 1996-02-14 EP EP01114005A patent/EP1160256B2/de not_active Expired - Lifetime
- 1996-02-14 CA CA002212887A patent/CA2212887C/en not_active Expired - Lifetime
- 1996-02-14 DK DK01114005.0T patent/DK1160256T4/da active
- 1996-02-14 DE DE69617916T patent/DE69617916T2/de not_active Expired - Fee Related
- 1996-02-14 DK DK96906616T patent/DK0809656T3/da active
- 1996-02-14 WO PCT/US1996/002491 patent/WO1996025435A1/en active IP Right Grant
- 1996-02-14 ES ES07012421T patent/ES2400674T3/es not_active Expired - Lifetime
- 1996-02-14 ES ES96906616T patent/ES2167548T3/es not_active Expired - Lifetime
- 1996-02-14 PT PT01114005T patent/PT1160256E/pt unknown
- 1996-02-14 AT AT01114005T patent/ATE365750T1/de active
- 1996-02-14 ES ES01114005T patent/ES2288896T5/es not_active Expired - Lifetime
- 1996-02-14 PT PT96906616T patent/PT809656E/pt unknown
- 1996-02-14 JP JP08525208A patent/JP3115606B2/ja not_active Expired - Fee Related
- 1996-02-14 EP EP96906616A patent/EP0809656B1/de not_active Expired - Lifetime
-
2008
- 2008-04-10 HK HK08104065.4A patent/HK1114105A1/xx not_active IP Right Cessation
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