DE69637724D1 - Polypeptide mit spezieller, funktioneller domäne, verfahren zu ihrer identifikation und anwendungen derselben - Google Patents
Polypeptide mit spezieller, funktioneller domäne, verfahren zu ihrer identifikation und anwendungen derselbenInfo
- Publication number
- DE69637724D1 DE69637724D1 DE69637724T DE69637724T DE69637724D1 DE 69637724 D1 DE69637724 D1 DE 69637724D1 DE 69637724 T DE69637724 T DE 69637724T DE 69637724 T DE69637724 T DE 69637724T DE 69637724 D1 DE69637724 D1 DE 69637724D1
- Authority
- DE
- Germany
- Prior art keywords
- polypeptides
- applications
- identification
- special
- functional domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41787295A | 1995-04-07 | 1995-04-07 | |
US08/630,915 US6309820B1 (en) | 1995-04-07 | 1996-04-03 | Polypeptides having a functional domain of interest and methods of identifying and using same |
PCT/US1996/004454 WO1996031625A1 (en) | 1995-04-07 | 1996-04-04 | Polypeptides having a functional domain of interest and methods of identifying and using same |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69637724D1 true DE69637724D1 (de) | 2008-12-04 |
Family
ID=23655708
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69637724T Expired - Fee Related DE69637724D1 (de) | 1995-04-07 | 1996-04-04 | Polypeptide mit spezieller, funktioneller domäne, verfahren zu ihrer identifikation und anwendungen derselben |
Country Status (4)
Country | Link |
---|---|
US (1) | US6309820B1 (de) |
AT (1) | ATE412067T1 (de) |
DE (1) | DE69637724D1 (de) |
ZA (1) | ZA962813B (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6184205B1 (en) * | 1994-07-22 | 2001-02-06 | University Of North Carolina At Chapel Hill | GRB2 SH3 binding peptides and methods of isolating and using same |
WO1999040434A1 (en) | 1998-02-04 | 1999-08-12 | Invitrogen Corporation | Microarrays and uses therefor |
US7118886B1 (en) * | 1998-04-27 | 2006-10-10 | Hsc Research And Development Limited Partnership | Ese genes and proteins |
US6406921B1 (en) * | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
US6831063B1 (en) * | 1999-08-31 | 2004-12-14 | The Wistar Institute Of Anatomy And Biology | Bridging Integrator-2(Bin2) nucleic acid molecules and proteins and uses therefor |
US7977119B2 (en) * | 2004-12-08 | 2011-07-12 | Agilent Technologies, Inc. | Chemical arrays and methods of using the same |
US9006173B2 (en) * | 2006-05-10 | 2015-04-14 | University Of Kentucky Research Foundation | Microcystins as agents for treatment of cancer |
FI126633B (en) * | 2015-07-10 | 2017-03-15 | Next Biomed Therapies Oy | Method of Preparation of a Library comprising Recombinant Derivatives of the SH3 Domain of Nephrocystin (NPHP1) |
CN112625112B (zh) * | 2020-12-16 | 2022-03-29 | 熊猫乳品集团股份有限公司 | 一种生物活性多肽paapaqlpkki及其制备方法和应用 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5866363A (en) * | 1985-08-28 | 1999-02-02 | Pieczenik; George | Method and means for sorting and identifying biological information |
EP1892296A1 (de) | 1988-09-02 | 2008-02-27 | Dyax Corporation | Herstellung und Auswahl von Rekombinantproteinen mit verschiedenen Bindestellen |
US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
US5198346A (en) | 1989-01-06 | 1993-03-30 | Protein Engineering Corp. | Generation and selection of novel DNA-binding proteins and polypeptides |
US5096815A (en) | 1989-01-06 | 1992-03-17 | Protein Engineering Corporation | Generation and selection of novel dna-binding proteins and polypeptides |
US5723286A (en) | 1990-06-20 | 1998-03-03 | Affymax Technologies N.V. | Peptide library and screening systems |
GB9107434D0 (en) | 1991-04-09 | 1991-05-22 | Medical Res Council | Peptide-based assay |
US5270170A (en) * | 1991-10-16 | 1993-12-14 | Affymax Technologies N.V. | Peptide library and screening method |
KR100257941B1 (ko) | 1992-03-06 | 2000-06-01 | 휴버스윗 에이치. 밴 | 면역학적으로 중요한 에피토프에 상응하는 펩티드의 측정 방법 및 면역학적으로 중요한 에피토프에 상응하는 항체 또는 비오티닐화된 펩티드의 측정 방법에 상기 펩티드를 사용하는 방법, 상기 펩티드의 제조 방법 및 상기 펩티드를 함유하는 조성물 |
WO1995010296A1 (en) | 1993-10-12 | 1995-04-20 | Glycomed Incorporated | A library of glyco-peptides useful for identification of cell adhesion inhibitors |
WO1995024419A1 (en) | 1994-03-11 | 1995-09-14 | Ariad Pharmaceuticals, Inc. | Methods and materials for identifying inhibitors of molecular interactions mediated by sh3 domains |
US5541109A (en) | 1994-04-19 | 1996-07-30 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Expression cloning of c-src SH3-domain binding proteins |
GB9509844D0 (en) | 1995-05-16 | 1995-07-12 | Cancer Res Campaign Tech | Screening for inhibitors of TCR-MHC interactions |
US6011137A (en) | 1996-04-03 | 2000-01-04 | University Of North Carolina At Chapel Hill | Identification and isolation of novel polypeptides having WW domains and methods of using same |
-
1996
- 1996-04-03 US US08/630,915 patent/US6309820B1/en not_active Expired - Fee Related
- 1996-04-04 DE DE69637724T patent/DE69637724D1/de not_active Expired - Fee Related
- 1996-04-04 AT AT96910696T patent/ATE412067T1/de not_active IP Right Cessation
- 1996-04-09 ZA ZA962813A patent/ZA962813B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
ZA962813B (en) | 1996-10-09 |
US6309820B1 (en) | 2001-10-30 |
ATE412067T1 (de) | 2008-11-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |