DE69701662T2 - N-substituierte zyklische Amine, ihre Herstellungsverfahren und sie enthaltende pharmazeutische Zusammensetzungen - Google Patents
N-substituierte zyklische Amine, ihre Herstellungsverfahren und sie enthaltende pharmazeutische ZusammensetzungenInfo
- Publication number
- DE69701662T2 DE69701662T2 DE69701662T DE69701662T DE69701662T2 DE 69701662 T2 DE69701662 T2 DE 69701662T2 DE 69701662 T DE69701662 T DE 69701662T DE 69701662 T DE69701662 T DE 69701662T DE 69701662 T2 DE69701662 T2 DE 69701662T2
- Authority
- DE
- Germany
- Prior art keywords
- halo
- saturated
- optionally substituted
- unsaturated
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9611501A FR2753706B1 (fr) | 1996-09-20 | 1996-09-20 | Nouvelles amines cycliques n-substituees, leur procede de preparation et les compositions pharmaceutiques les renfermant |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69701662D1 DE69701662D1 (de) | 2000-05-18 |
DE69701662T2 true DE69701662T2 (de) | 2000-11-23 |
Family
ID=9495928
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69701662T Expired - Fee Related DE69701662T2 (de) | 1996-09-20 | 1997-09-19 | N-substituierte zyklische Amine, ihre Herstellungsverfahren und sie enthaltende pharmazeutische Zusammensetzungen |
Country Status (18)
Country | Link |
---|---|
US (1) | US5919801A (de) |
EP (1) | EP0831090B1 (de) |
JP (1) | JPH10101645A (de) |
AT (1) | ATE191717T1 (de) |
AU (1) | AU718489B2 (de) |
BR (1) | BR9704757A (de) |
CA (1) | CA2216664C (de) |
DE (1) | DE69701662T2 (de) |
DK (1) | DK0831090T3 (de) |
ES (1) | ES2147427T3 (de) |
FR (1) | FR2753706B1 (de) |
GR (1) | GR3033509T3 (de) |
HU (1) | HU221811B1 (de) |
NO (1) | NO313997B1 (de) |
NZ (1) | NZ328789A (de) |
PL (1) | PL322192A1 (de) |
PT (1) | PT831090E (de) |
ZA (1) | ZA978462B (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6867209B1 (en) | 1998-05-22 | 2005-03-15 | Scios, Inc. | Indole-type derivatives as inhibitors of p38 kinase |
HUP0203657A3 (en) * | 1998-05-22 | 2005-03-29 | Scios Inc Sunnyvale | Heterocyclic compounds and methods to treat cardiac failure and other disorders |
US6130235A (en) * | 1998-05-22 | 2000-10-10 | Scios Inc. | Compounds and methods to treat cardiac failure and other disorders |
US6340685B1 (en) | 1998-05-22 | 2002-01-22 | Scios, Inc. | Compounds and methods to treat cardiac failure and other disorders |
US6448257B1 (en) | 1998-05-22 | 2002-09-10 | Scios, Inc. | Compounds and methods to treat cardiac failure and other disorders |
US6589954B1 (en) | 1998-05-22 | 2003-07-08 | Scios, Inc. | Compounds and methods to treat cardiac failure and other disorders |
AU754379B2 (en) | 1998-08-26 | 2002-11-14 | Smithkline Beecham Corporation | Therapies for treating pulmonary diseases |
IL146309A (en) | 1999-05-21 | 2008-03-20 | Scios Inc | Derivatives of the indole type and pharmaceutical preparations containing them as inhibitors of kinase p38 |
KR100515905B1 (ko) * | 2000-01-31 | 2005-09-21 | 주식회사 엘지생명과학 | 피롤아미드의 새로운 제조방법 |
MXPA02007688A (es) * | 2000-02-08 | 2002-12-13 | Smithkline Beecham Corp | Metodo y composiciones para tratar una enfermedad antiinflamatoria. |
US20030207845A1 (en) * | 2001-02-08 | 2003-11-06 | Keating Elizabeth T. | Method and compositions for treating an inflammatory disease |
DE10035928A1 (de) | 2000-07-21 | 2002-03-07 | Asta Medica Ag | Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel |
DE10035927A1 (de) | 2000-07-21 | 2002-03-07 | Asta Medica Ag | Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel |
CA2418313C (en) * | 2000-08-11 | 2008-09-23 | Ono Pharmaceutical Co., Ltd. | Piperidine derivatives and agent comprising the derivative as active ingredient |
US20040219552A1 (en) * | 2001-08-14 | 2004-11-04 | Ali Ait Ikhlef | Novel molecular target for neurotoxicity |
FR2856595B1 (fr) * | 2003-06-27 | 2008-05-30 | Exonhit Therapeutics Sa | Methodes et compositions pour le traitement de deficits cognitifs. |
EP2674417A3 (de) * | 2007-11-21 | 2014-04-09 | Decode Genetics EHF | Biaryl-PDE4-Inhibitoren zur Behandlung von Entzündungen |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR6850M (de) * | 1967-12-05 | 1969-04-08 | ||
US5459151A (en) * | 1993-04-30 | 1995-10-17 | American Home Products Corporation | N-acyl substituted phenyl piperidines as bronchodilators and antiinflammatory agents |
US5434158A (en) * | 1994-04-26 | 1995-07-18 | Merck & Co., Inc. | Spiro-substituted azacycles as neurokinin-3 antagonists |
US5530012A (en) * | 1994-12-22 | 1996-06-25 | Bristol-Myers Squibb Co. | 3-alkoxybenzylpiperidine derivatives as melatonergic agents |
US5703239A (en) * | 1995-06-02 | 1997-12-30 | Bristol-Myers Squibb Company | Indanylpiperidines as melatonergic agents |
-
1996
- 1996-09-20 FR FR9611501A patent/FR2753706B1/fr not_active Expired - Fee Related
-
1997
- 1997-09-12 JP JP9248357A patent/JPH10101645A/ja active Pending
- 1997-09-15 NO NO19974253A patent/NO313997B1/no unknown
- 1997-09-19 DE DE69701662T patent/DE69701662T2/de not_active Expired - Fee Related
- 1997-09-19 AT AT97402175T patent/ATE191717T1/de not_active IP Right Cessation
- 1997-09-19 HU HU9701561A patent/HU221811B1/hu not_active IP Right Cessation
- 1997-09-19 US US08/934,409 patent/US5919801A/en not_active Expired - Fee Related
- 1997-09-19 ES ES97402175T patent/ES2147427T3/es not_active Expired - Lifetime
- 1997-09-19 CA CA002216664A patent/CA2216664C/fr not_active Expired - Fee Related
- 1997-09-19 ZA ZA9708462A patent/ZA978462B/xx unknown
- 1997-09-19 EP EP97402175A patent/EP0831090B1/de not_active Expired - Lifetime
- 1997-09-19 DK DK97402175T patent/DK0831090T3/da active
- 1997-09-19 AU AU38362/97A patent/AU718489B2/en not_active Ceased
- 1997-09-19 PL PL97322192A patent/PL322192A1/xx unknown
- 1997-09-19 BR BR9704757A patent/BR9704757A/pt unknown
- 1997-09-19 NZ NZ328789A patent/NZ328789A/en unknown
- 1997-09-19 PT PT97402175T patent/PT831090E/pt unknown
-
2000
- 2000-05-25 GR GR20000401200T patent/GR3033509T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HU9701561D0 (en) | 1997-11-28 |
ATE191717T1 (de) | 2000-04-15 |
CA2216664C (fr) | 2002-05-21 |
CA2216664A1 (fr) | 1998-03-20 |
DE69701662D1 (de) | 2000-05-18 |
HUP9701561A2 (hu) | 1998-05-28 |
PT831090E (pt) | 2000-07-31 |
US5919801A (en) | 1999-07-06 |
PL322192A1 (en) | 1998-03-30 |
AU718489B2 (en) | 2000-04-13 |
FR2753706B1 (fr) | 1998-10-30 |
BR9704757A (pt) | 1998-09-01 |
HUP9701561A3 (en) | 1998-07-28 |
NO974253D0 (no) | 1997-09-15 |
GR3033509T3 (en) | 2000-09-29 |
EP0831090B1 (de) | 2000-04-12 |
NO313997B1 (no) | 2003-01-13 |
NZ328789A (en) | 1998-02-26 |
EP0831090A1 (de) | 1998-03-25 |
DK0831090T3 (da) | 2000-09-11 |
ES2147427T3 (es) | 2000-09-01 |
HU221811B1 (hu) | 2003-01-28 |
FR2753706A1 (fr) | 1998-03-27 |
NO974253L (no) | 1998-03-23 |
JPH10101645A (ja) | 1998-04-21 |
ZA978462B (en) | 1998-03-24 |
AU3836297A (en) | 1998-03-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: LES LABORATOIRES SERVIER, NEUILLY SUR SEINE, FR |
|
8339 | Ceased/non-payment of the annual fee |