DE69725611D1 - Nicht-Nukleotid verknüpfende Reagentien - Google Patents
Nicht-Nukleotid verknüpfende ReagentienInfo
- Publication number
- DE69725611D1 DE69725611D1 DE69725611T DE69725611T DE69725611D1 DE 69725611 D1 DE69725611 D1 DE 69725611D1 DE 69725611 T DE69725611 T DE 69725611T DE 69725611 T DE69725611 T DE 69725611T DE 69725611 D1 DE69725611 D1 DE 69725611D1
- Authority
- DE
- Germany
- Prior art keywords
- pct
- reagents
- nucleotide
- linking reagents
- nucleotide linking
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/22—Amides of acids of phosphorus
- C07F9/24—Esteramides
- C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
- C07F9/2416—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of cycloaliphatic alcohols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64782096A | 1996-05-15 | 1996-05-15 | |
| US647820 | 1996-05-15 | ||
| PCT/US1997/009094 WO1997043451A1 (en) | 1996-05-15 | 1997-05-15 | Non-nucleotide linking reagents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69725611D1 true DE69725611D1 (de) | 2003-11-20 |
| DE69725611T2 DE69725611T2 (de) | 2004-07-29 |
Family
ID=24598396
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69725611T Expired - Fee Related DE69725611T2 (de) | 1996-05-15 | 1997-05-15 | Nicht-Nukleotid verknüpfende Reagentien |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6130323A (de) |
| EP (1) | EP0954606B1 (de) |
| JP (1) | JP2001509784A (de) |
| AT (1) | ATE252158T1 (de) |
| AU (1) | AU733647B2 (de) |
| CA (1) | CA2253969A1 (de) |
| DE (1) | DE69725611T2 (de) |
| WO (1) | WO1997043451A1 (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4004230B2 (ja) * | 1998-11-06 | 2007-11-07 | 株式会社三菱化学ヤトロン | 架橋アビジン含有新規複合体、架橋アビジンを用いる分析方法、並びに分析用試薬及びキット |
| JP5213297B2 (ja) | 2000-08-11 | 2013-06-19 | ユニバーシティ オブ ユタ リサーチ ファウンデーション | 単一ラベルオリゴヌクレオチド・プローブ |
| US7560231B2 (en) * | 2002-12-20 | 2009-07-14 | Roche Molecular Systems, Inc. | Mannitol and glucitol derivatives |
| WO2004089295A2 (en) * | 2003-04-01 | 2004-10-21 | Chromagen, Inc. | Homogeneous and heterogeneous assay methods using nucleation centers and novel covalent chemistries for the rapid measurement of phosphorylation and de-phosphorylation |
| CA2463719A1 (en) | 2003-04-05 | 2004-10-05 | F. Hoffmann-La Roche Ag | Nucleotide analogs with six membered rings |
| EP1502958A1 (de) * | 2003-08-01 | 2005-02-02 | Roche Diagnostics GmbH | Neues Format zur Detektion von Heissstart- und Echtzeit-Polymerasekettenreaktion |
| EP1700922B1 (de) | 2005-03-10 | 2016-08-24 | Roche Diagnostics GmbH | 3-Substituierte 5-Nitroindolderivate und diese enthaltende markierte Oligonukleotidsonden |
| ES2332139T3 (es) | 2005-11-23 | 2010-01-27 | F. Hoffmann-La Roche Ag | Polinucleotidos con mimetico de fosfato. |
| US7759470B2 (en) | 2006-02-20 | 2010-07-20 | Roche Diagnostics Operations, Inc. | Labeling reagent |
| EP2156370B1 (de) | 2007-05-14 | 2011-10-12 | Historx, Inc. | Abteilungsauftrennung durch pixelcharakterisierung unter verwendung von bilddatenclusterung |
| ES2599902T3 (es) | 2007-06-15 | 2017-02-06 | Novartis Ag | Sistema y método de microscopio para obtener datos de muestra normalizados |
| CA2604317C (en) | 2007-08-06 | 2017-02-28 | Historx, Inc. | Methods and system for validating sample images for quantitative immunoassays |
| CA2596204C (en) | 2007-08-07 | 2019-02-26 | Historx, Inc. | Method and system for determining an optimal dilution of a reagent |
| US7978258B2 (en) | 2007-08-31 | 2011-07-12 | Historx, Inc. | Automatic exposure time selection for imaging tissue |
| US9240043B2 (en) | 2008-09-16 | 2016-01-19 | Novartis Ag | Reproducible quantification of biomarker expression |
| RU2015153109A (ru) | 2009-09-16 | 2019-01-15 | Дженентек, Инк. | Содержащие суперспираль и/или привязку белковые комплексы и их применения |
| TW201138821A (en) | 2010-03-26 | 2011-11-16 | Roche Glycart Ag | Bispecific antibodies |
| SG191153A1 (en) | 2010-12-23 | 2013-07-31 | Hoffmann La Roche | Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery |
| EP2659269B1 (de) | 2010-12-23 | 2016-10-26 | Roche Diagniostics GmbH | Erkennung von posttranslational modifiziertem polypeptid durch ein bivalentes bindungsmolekül |
| KR20140127854A (ko) | 2012-02-10 | 2014-11-04 | 제넨테크, 인크. | 단일-쇄 항체 및 다른 이종다량체 |
| WO2014001324A1 (en) | 2012-06-27 | 2014-01-03 | Hoffmann-La Roche Ag | Method for selection and production of tailor-made highly selective and multi-specific targeting entities containing at least two different binding entities and uses thereof |
| RU2015100656A (ru) | 2012-06-27 | 2016-08-20 | Ф. Хоффманн-Ля Рош Аг | Способ получения конъюгатов fc-фрагмента антитела, включающих по меньшей мере одну связывающую группировку, которая специфически связывается с мишенью, и их применения |
| EP3227332B1 (de) | 2014-12-03 | 2019-11-06 | F.Hoffmann-La Roche Ag | Multispezifische antikörper |
| US10781175B2 (en) * | 2016-07-15 | 2020-09-22 | Am Chemicals Llc | Solid supports and phosphoramidite building blocks for oligonucleotide conjugates |
| CN108219513B (zh) * | 2018-03-14 | 2019-11-08 | 青岛科技大学 | 一种羧基荧光素的制备方法 |
-
1997
- 1997-05-15 AT AT97926780T patent/ATE252158T1/de not_active IP Right Cessation
- 1997-05-15 EP EP97926780A patent/EP0954606B1/de not_active Expired - Lifetime
- 1997-05-15 WO PCT/US1997/009094 patent/WO1997043451A1/en active IP Right Grant
- 1997-05-15 CA CA002253969A patent/CA2253969A1/en not_active Abandoned
- 1997-05-15 US US09/171,925 patent/US6130323A/en not_active Expired - Fee Related
- 1997-05-15 JP JP54122597A patent/JP2001509784A/ja not_active Ceased
- 1997-05-15 DE DE69725611T patent/DE69725611T2/de not_active Expired - Fee Related
- 1997-05-15 AU AU31465/97A patent/AU733647B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0954606A1 (de) | 1999-11-10 |
| EP0954606A4 (de) | 1999-12-22 |
| US6130323A (en) | 2000-10-10 |
| AU3146597A (en) | 1997-12-05 |
| ATE252158T1 (de) | 2003-11-15 |
| CA2253969A1 (en) | 1997-11-20 |
| AU733647B2 (en) | 2001-05-17 |
| EP0954606B1 (de) | 2003-10-15 |
| DE69725611T2 (de) | 2004-07-29 |
| JP2001509784A (ja) | 2001-07-24 |
| WO1997043451A1 (en) | 1997-11-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |