DE69733560D1 - TESTVERFAHREN UND REAGENZIEN ZUR QUANTIFIZIERUNG VON hBNP - Google Patents
TESTVERFAHREN UND REAGENZIEN ZUR QUANTIFIZIERUNG VON hBNPInfo
- Publication number
- DE69733560D1 DE69733560D1 DE69733560T DE69733560T DE69733560D1 DE 69733560 D1 DE69733560 D1 DE 69733560D1 DE 69733560 T DE69733560 T DE 69733560T DE 69733560 T DE69733560 T DE 69733560T DE 69733560 D1 DE69733560 D1 DE 69733560D1
- Authority
- DE
- Germany
- Prior art keywords
- antibody
- hbnp
- quantifying
- reagents
- test procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/839—Nerves; brain
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/841—Muscles; heart
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61017296A | 1996-03-04 | 1996-03-04 | |
US610172 | 1996-03-04 | ||
PCT/US1997/003163 WO1997032900A1 (en) | 1996-03-04 | 1997-03-04 | ASSAY AND REAGENTS FOR QUANTIFYING hBNP |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69733560D1 true DE69733560D1 (de) | 2005-07-21 |
DE69733560T2 DE69733560T2 (de) | 2006-05-11 |
Family
ID=24443982
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69733560T Expired - Lifetime DE69733560T2 (de) | 1996-03-04 | 1997-03-04 | TESTVERFAHREN UND REAGENZIEN ZUR QUANTIFIZIERUNG VON hBNP |
Country Status (13)
Country | Link |
---|---|
US (3) | US6162902A (de) |
EP (3) | EP1557431B1 (de) |
JP (3) | JP4049816B2 (de) |
AT (1) | ATE297950T1 (de) |
AU (1) | AU1981597A (de) |
CA (1) | CA2248140C (de) |
DE (1) | DE69733560T2 (de) |
DK (2) | DK0914344T3 (de) |
ES (1) | ES2243979T3 (de) |
HK (1) | HK1078096A1 (de) |
PT (2) | PT2292662E (de) |
WO (1) | WO1997032900A1 (de) |
ZA (1) | ZA971864B (de) |
Families Citing this family (76)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2665850B2 (ja) * | 1991-11-14 | 1997-10-22 | 塩野義製薬株式会社 | hBNPのC端を認識するモノクロ−ナル抗体 |
US6379975B1 (en) * | 1996-11-27 | 2002-04-30 | T.A.C. Thrombosis And Coagulation Aktiebolag | Methods and reagents for determining protein S |
US6117644A (en) * | 1998-06-04 | 2000-09-12 | Ottawa Heart Institute Research Corporation | Predicting and detecting cardiac allograft rejection |
GB9827348D0 (en) * | 1998-12-12 | 1999-02-03 | Univ Leicester | Natriuretic peptide |
AU5043900A (en) * | 1999-05-24 | 2000-12-12 | Mayo Foundation For Medical Education And Research | Adenovirus vectors encoding brain natriuretic peptide |
US6407211B1 (en) | 1999-12-17 | 2002-06-18 | Mayo Foundation For Medical Education And Research | Chimeric natriuretic peptides |
US20060228364A1 (en) * | 1999-12-24 | 2006-10-12 | Genentech, Inc. | Serum albumin binding peptides for tumor targeting |
US7396917B2 (en) * | 2000-12-05 | 2008-07-08 | Alexion Pharmaceuticals, Inc. | Rationally designed antibodies |
ATE544785T1 (de) | 2000-12-05 | 2012-02-15 | Alexion Pharma Inc | Rationell entworfene antikörper |
US20040253242A1 (en) * | 2000-12-05 | 2004-12-16 | Bowdish Katherine S. | Rationally designed antibodies |
AU2002231008A1 (en) * | 2000-12-19 | 2002-07-01 | Instrumentation Laboratory Co. | Free analyte detection system |
US7524635B2 (en) * | 2003-04-17 | 2009-04-28 | Biosite Incorporated | Methods and compositions for measuring natriuretic peptides and uses thereof |
US20030199000A1 (en) * | 2001-08-20 | 2003-10-23 | Valkirs Gunars E. | Diagnostic markers of stroke and cerebral injury and methods of use thereof |
US20030219734A1 (en) * | 2001-04-13 | 2003-11-27 | Biosite Incorporated | Polypeptides related to natriuretic peptides and methods of their identification and use |
US7632647B2 (en) * | 2001-04-13 | 2009-12-15 | Biosite Incorporated | Use of B-type natriuretic peptide as a prognostic indicator in acute coronary syndromes |
WO2003016910A1 (en) | 2001-08-20 | 2003-02-27 | Biosite, Inc. | Diagnostic markers of stroke and cerebral injury and methods of use thereof |
US20040176914A1 (en) * | 2001-04-13 | 2004-09-09 | Biosite Incorporated | Methods and compositions for measuring biologically active natriuretic peptides and for improving their therapeutic potential |
DE60235416D1 (de) * | 2001-05-04 | 2010-04-01 | Biosite Inc | Diagnostische Marker der akuten koronaren Syndrome und ihre Verwendungen |
US7608406B2 (en) * | 2001-08-20 | 2009-10-27 | Biosite, Inc. | Diagnostic markers of stroke and cerebral injury and methods of use thereof |
US20040219509A1 (en) * | 2001-08-20 | 2004-11-04 | Biosite, Inc. | Diagnostic markers of stroke and cerebral injury and methods of use thereof |
US20040209307A1 (en) * | 2001-08-20 | 2004-10-21 | Biosite Incorporated | Diagnostic markers of stroke and cerebral injury and methods of use thereof |
US6461828B1 (en) | 2001-09-04 | 2002-10-08 | Syn X Pharma | Conjunctive analysis of biological marker expression for diagnosing organ failure |
AUPS169202A0 (en) * | 2002-04-11 | 2002-05-16 | Goetze, Jens Peter | Neuropeptide assay |
FR2843396B1 (fr) * | 2002-08-07 | 2005-04-15 | Bio Rad Pasteur | Anticorps specifiques pour le diagnostic de l'insuffisance cardiaque |
GB0224425D0 (en) * | 2002-10-21 | 2002-11-27 | Univ Leicester | Method for prediction of cardiac disease |
AU2003285200A1 (en) * | 2002-11-09 | 2004-06-03 | Nobex Corporation | Modified carbamate-containing prodrugs and methods of synthesizing same |
US8263325B2 (en) * | 2002-11-15 | 2012-09-11 | Ottawa Heart Institute Research Corporation | Predicting, detecting and monitoring treatment of cardiomyopathies and myocarditis |
US6960472B2 (en) * | 2002-11-18 | 2005-11-01 | Ottawa Heart Institute Research Corporation | Monoclonal antibodies against N-Terminus proBNP |
AU2003297583B2 (en) * | 2002-11-26 | 2010-01-14 | Biocon, Ltd | Modified naturetic compounds, conjugates, and uses thereof |
US7648962B2 (en) * | 2002-11-26 | 2010-01-19 | Biocon Limited | Natriuretic compounds, conjugates, and uses thereof |
WO2004082639A2 (en) * | 2003-03-19 | 2004-09-30 | Baylor College Of Medicine | Detecting coronary artery disease with bnp during stress testing |
WO2004094460A2 (en) | 2003-04-17 | 2004-11-04 | Ciphergen Biosystems, Inc. | Polypeptides related to natriuretic peptides and methods of their identification and use |
WO2004105575A2 (en) * | 2003-05-29 | 2004-12-09 | Trustee Of Darmouth College | A method for detecting cardiac ischemia via changes in b-natriuretic peptide levels |
WO2005000095A2 (en) | 2003-06-20 | 2005-01-06 | Mayo Foundation For Medical Education And Research | Isoforms of brain natriuretic peptide |
GB2403533A (en) | 2003-06-30 | 2005-01-05 | Orion Corp | Atrial natriuretic peptide and brain natriuretic peptide and assays and uses thereof |
US7445933B2 (en) * | 2003-07-16 | 2008-11-04 | Abbott Laboratories, Inc. | Stable calibrators or controls for measuring human natriuretic peptides |
US7291501B2 (en) * | 2003-07-16 | 2007-11-06 | Abbott Laboratories | Stable compositions for measuring human natriuretic peptides |
US7632234B2 (en) * | 2003-08-29 | 2009-12-15 | Medtronic, Inc. | Implantable biosensor devices for monitoring cardiac marker molecules |
KR20050062836A (ko) * | 2003-12-18 | 2005-06-28 | 학교법인 대양학원 | 트랜스코딩 방법 및 장치 |
US20080207505A1 (en) * | 2005-01-12 | 2008-08-28 | James Kenneth D | Bna Conjugates and Methods of Use |
FR2863269B1 (fr) * | 2005-01-14 | 2006-05-26 | Bio Rad Pasteur | Peptides specifiques pour le diagnostic de l'insuffisance cardiaque |
US7731965B2 (en) | 2005-02-17 | 2010-06-08 | Abbott Lab | Human ring specific BNP antibodies |
US20080227713A1 (en) * | 2005-10-03 | 2008-09-18 | Protter Andrew A | Oxidized Human Bnp |
US7939069B2 (en) | 2005-11-09 | 2011-05-10 | Abbott Laboratories | Human BNP immunospecific antibodies |
JP5364378B2 (ja) * | 2005-11-09 | 2013-12-11 | アボット・ラボラトリーズ | ヒトbnp免疫特異的抗体 |
EP2004633A4 (de) * | 2006-03-30 | 2009-08-26 | Palatin Technologies Inc | Lineare natriuretische peptidkonstrukte |
US8580746B2 (en) * | 2006-03-30 | 2013-11-12 | Palatin Technologies, Inc. | Amide linkage cyclic natriuretic peptide constructs |
BRPI0709427A2 (pt) | 2006-03-30 | 2011-07-12 | Palatin Technologies Inc | "construto cìclico, composição farmacêutica e uso de um composto |
CN101501067B (zh) * | 2006-08-08 | 2013-01-16 | 梅约医学教育与研究基金会 | 利尿和利尿钠的多肽 |
US20080064045A1 (en) | 2006-09-07 | 2008-03-13 | Huaiqin Wu | Biomarker fragments for the detection of human BNP |
JP4851367B2 (ja) * | 2007-03-05 | 2012-01-11 | 富士フイルム株式会社 | ローカルプラズモン増強蛍光センサ |
AT504942B1 (de) | 2007-03-07 | 2009-08-15 | Biomedica Medizinprodukte Gmbh | Verfahren zur bestimmung von probnp |
WO2008137991A1 (en) * | 2007-05-08 | 2008-11-13 | Abbott Laboratories | Human b-type natriuretic peptide assay having reduced cross-reactivity with other peptide forms |
FR2919611B1 (fr) * | 2007-08-03 | 2009-10-23 | Bio Rad Pasteur Sa | Nouvel epitope du bnp (1-32) et anticorps diriges contre cet epitope |
US8357656B2 (en) * | 2007-09-15 | 2013-01-22 | Mayo Foundation For Medical Education And Research | Natriuretic peptide receptor-C agonists |
PL2612868T3 (pl) * | 2007-11-01 | 2018-12-31 | Astellas Pharma Inc. | Immunosupresyjne polipeptydy i kwasy nukleinowe |
WO2009086411A2 (en) * | 2007-12-27 | 2009-07-09 | Abbott Laboratories | Negative mimic antibody for use as a blocking reagent in bnp immunoassays |
US9482677B2 (en) | 2008-02-27 | 2016-11-01 | Scios Inc. | Method, composition and device for sampling natriuretic peptides in a biological fluid |
US20090286256A1 (en) * | 2008-05-19 | 2009-11-19 | Abbott Laboratories | Isolated human autoantibodies to natriuretic peptides and methods and kits for detecting human autoantibodies to natriuretic peptides |
US20090286329A1 (en) * | 2008-05-19 | 2009-11-19 | Abbott Laboratoires | Isolated human autoantibodies to natriuretic peptides and methods and kits for detecting human autoantibodies to natriuretic peptides |
US8455212B2 (en) | 2009-11-21 | 2013-06-04 | Abbott Laboratories | Assays for human NT-pro B-type natriuretic peptide, human pro B-type natriuretic peptide and human B-type natriuretic peptide |
JP5810514B2 (ja) * | 2009-12-07 | 2015-11-11 | 東ソー株式会社 | タグペプチド |
WO2012077643A1 (ja) * | 2010-12-09 | 2012-06-14 | 東レ株式会社 | cofilin1タンパク質の免疫学的測定方法 |
JP2012140331A (ja) * | 2010-12-28 | 2012-07-26 | Tosoh Corp | タグペプチド |
JP2014525439A (ja) | 2011-08-30 | 2014-09-29 | メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ | ナトリウム利尿ポリペプチド |
WO2013103896A1 (en) | 2012-01-06 | 2013-07-11 | Mayo Foundation For Medical Education And Research | Treating cardiovascular or renal diseases |
JP2014028770A (ja) * | 2012-07-31 | 2014-02-13 | Tosoh Corp | ヒトb型ナトリウム利尿ペプチド特異抗体およびそれを用いた測定法 |
JP2014091719A (ja) * | 2012-11-05 | 2014-05-19 | Tosoh Corp | ヒトb型ナトリウム利尿ペプチドの3−32位に相当するポリペプチドに対する特異抗体およびそれを用いた測定法 |
JP2015137272A (ja) * | 2014-01-24 | 2015-07-30 | 東ソー株式会社 | 新規のペプチド及び疾患の検出方法 |
CN104569429B (zh) * | 2015-01-04 | 2017-01-18 | 深圳市艾瑞生物科技有限公司 | 一种快速定量检测脑钠肽的均相荧光免疫试剂组及其制备方法 |
JP6772498B2 (ja) | 2016-03-18 | 2020-10-21 | 株式会社Sumco | 基板収納容器 |
US11193947B2 (en) | 2016-06-03 | 2021-12-07 | Cedars-Sinai Medical Center | B-type natriuretic peptide proteolytic assay for cardiovascular disease risk assessment |
EP3464339A4 (de) * | 2016-06-03 | 2019-12-25 | Cedars-Sinai Medical Center | Proteolytischer test von b-typ-natriuretischem peptid zur beurteilung des risikos von herz-kreislauf-erkrankungen |
CN112094338B (zh) * | 2019-05-14 | 2022-03-25 | 深圳市亚辉龙生物科技股份有限公司 | 氨基末端脑钠肽前体多肽、偶联蛋白 |
CN113956355B (zh) * | 2021-07-26 | 2023-06-23 | 无锡傲锐东源生物科技有限公司 | 抗人脑利钠肽(bnp)兔单克隆抗体及其应用 |
WO2023190560A1 (ja) * | 2022-03-31 | 2023-10-05 | デンカ株式会社 | ヒトb型ナトリウム利尿ペプチド又はその前駆体若しくは分解物を検出するための方法、組成物、及びキット |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5114923A (en) | 1988-05-31 | 1992-05-19 | California Biotechnology Inc. | Recombinant techniques for production of novel natriuretic and vasodilator peptides |
JP2676114B2 (ja) * | 1990-04-16 | 1997-11-12 | 塩野義製薬株式会社 | hBNPを認識するモノクローナル抗体および該抗体を用いるhBNPの免疫測定法 |
JPH05207891A (ja) * | 1991-03-08 | 1993-08-20 | Shionogi & Co Ltd | 脳性ナトリウム利尿ペプチドの製造方法 |
JPH0556794A (ja) * | 1991-09-03 | 1993-03-09 | Dai Ichi Pure Chem Co Ltd | 生理活性ペプチドの製造法 |
JPH0568581A (ja) * | 1991-09-10 | 1993-03-23 | Dai Ichi Pure Chem Co Ltd | 生理活性ペプチドの製造法 |
JP2665850B2 (ja) * | 1991-11-14 | 1997-10-22 | 塩野義製薬株式会社 | hBNPのC端を認識するモノクロ−ナル抗体 |
DE4137730C2 (de) | 1991-11-15 | 1993-10-21 | Texas Instruments Deutschland | In einer Halbleiterschaltung integrierte Schaltungsanordnung |
GB9211686D0 (en) * | 1992-06-03 | 1992-07-15 | Medisinsk Innovation A S | Chemical compounds |
-
1997
- 1997-03-04 CA CA002248140A patent/CA2248140C/en not_active Expired - Lifetime
- 1997-03-04 DK DK97907946T patent/DK0914344T3/da active
- 1997-03-04 PT PT100131788T patent/PT2292662E/pt unknown
- 1997-03-04 EP EP05007745A patent/EP1557431B1/de not_active Expired - Lifetime
- 1997-03-04 EP EP10013178.8A patent/EP2292662B1/de not_active Expired - Lifetime
- 1997-03-04 AU AU19815/97A patent/AU1981597A/en not_active Abandoned
- 1997-03-04 AT AT97907946T patent/ATE297950T1/de active
- 1997-03-04 ZA ZA9701864A patent/ZA971864B/xx unknown
- 1997-03-04 DK DK10013178.8T patent/DK2292662T3/da active
- 1997-03-04 PT PT97907946T patent/PT914344E/pt unknown
- 1997-03-04 EP EP97907946A patent/EP0914344B8/de not_active Expired - Lifetime
- 1997-03-04 JP JP53184497A patent/JP4049816B2/ja not_active Expired - Lifetime
- 1997-03-04 DE DE69733560T patent/DE69733560T2/de not_active Expired - Lifetime
- 1997-03-04 WO PCT/US1997/003163 patent/WO1997032900A1/en active IP Right Grant
- 1997-03-04 ES ES97907946T patent/ES2243979T3/es not_active Expired - Lifetime
- 1997-10-01 US US08/942,456 patent/US6162902A/en not_active Expired - Lifetime
- 1997-10-01 US US08/942,332 patent/US6124430A/en not_active Expired - Lifetime
-
2000
- 2000-02-23 US US09/510,721 patent/US6376207B1/en not_active Expired - Lifetime
-
2006
- 2006-01-17 HK HK06100788.0A patent/HK1078096A1/xx not_active IP Right Cessation
-
2007
- 2007-02-07 JP JP2007028622A patent/JP2007169293A/ja not_active Withdrawn
-
2011
- 2011-01-14 JP JP2011006468A patent/JP2011102318A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2007169293A (ja) | 2007-07-05 |
JP2000507094A (ja) | 2000-06-13 |
JP2011102318A (ja) | 2011-05-26 |
AU1981597A (en) | 1997-09-22 |
EP2292662A2 (de) | 2011-03-09 |
EP0914344A1 (de) | 1999-05-12 |
DK0914344T3 (da) | 2005-08-29 |
ATE297950T1 (de) | 2005-07-15 |
EP1557431B1 (de) | 2012-08-15 |
CA2248140A1 (en) | 1997-09-12 |
EP2292662A3 (de) | 2011-07-13 |
ES2243979T3 (es) | 2005-12-01 |
CA2248140C (en) | 2005-02-01 |
ZA971864B (en) | 1997-12-18 |
US6162902A (en) | 2000-12-19 |
DK2292662T3 (da) | 2014-05-05 |
DE69733560T2 (de) | 2006-05-11 |
JP4049816B2 (ja) | 2008-02-20 |
PT2292662E (pt) | 2014-07-16 |
EP0914344B8 (de) | 2005-08-10 |
PT914344E (pt) | 2005-10-31 |
EP0914344B1 (de) | 2005-06-15 |
EP1557431A1 (de) | 2005-07-27 |
US6124430A (en) | 2000-09-26 |
US6376207B1 (en) | 2002-04-23 |
EP2292662B1 (de) | 2014-04-23 |
WO1997032900A1 (en) | 1997-09-12 |
HK1078096A1 (en) | 2006-03-03 |
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