DE69737460D1 - Verfahren zur in vitro vorbehandlung von myoblasten in der transplantation - Google Patents

Verfahren zur in vitro vorbehandlung von myoblasten in der transplantation

Info

Publication number
DE69737460D1
DE69737460D1 DE69737460T DE69737460T DE69737460D1 DE 69737460 D1 DE69737460 D1 DE 69737460D1 DE 69737460 T DE69737460 T DE 69737460T DE 69737460 T DE69737460 T DE 69737460T DE 69737460 D1 DE69737460 D1 DE 69737460D1
Authority
DE
Germany
Prior art keywords
fusion
promoting
transplantation
myoblasts
transplanted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69737460T
Other languages
English (en)
Other versions
DE69737460T2 (de
Inventor
Jacques P Tremblay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite Laval
Original Assignee
Universite Laval
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21844898&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69737460(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Universite Laval filed Critical Universite Laval
Application granted granted Critical
Publication of DE69737460D1 publication Critical patent/DE69737460D1/de
Publication of DE69737460T2 publication Critical patent/DE69737460T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/59—Lectins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323—Adult fibroblasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
DE69737460T 1996-10-18 1997-10-17 Verfahren zur in-vitro-vorbehandlung von myoblasten in der transplantation Expired - Lifetime DE69737460T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2869296P 1996-10-18 1996-10-18
US28692P 1996-10-18
PCT/CA1997/000774 WO1998017784A1 (en) 1996-10-18 1997-10-17 Method for in vitro preconditioning of myoblasts before transplantation

Publications (2)

Publication Number Publication Date
DE69737460D1 true DE69737460D1 (de) 2007-04-19
DE69737460T2 DE69737460T2 (de) 2008-04-10

Family

ID=21844898

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69737460T Expired - Lifetime DE69737460T2 (de) 1996-10-18 1997-10-17 Verfahren zur in-vitro-vorbehandlung von myoblasten in der transplantation

Country Status (7)

Country Link
US (3) US20020012657A1 (de)
EP (1) EP0946713B1 (de)
AT (1) ATE356199T1 (de)
AU (1) AU4613397A (de)
CA (1) CA2269096C (de)
DE (1) DE69737460T2 (de)
WO (1) WO1998017784A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1299201B1 (it) * 1998-05-08 2000-02-29 San Raffaele Centro Fond Fibroblasti modificati geneticamente e loro uso
US6284242B1 (en) * 1999-04-16 2001-09-04 Regents Of The University Of Michigan Method for enhancing myoblast migration and invasion in the context of gene therapy
WO2001007568A2 (en) * 1999-07-23 2001-02-01 Diacrin, Inc. Muscle cells and their use in cardiac repair
US20030113301A1 (en) * 1999-07-23 2003-06-19 Albert Edge Muscle cells and their use in cardiac repair
US7627373B2 (en) * 2002-11-30 2009-12-01 Cardiac Pacemakers, Inc. Method and apparatus for cell and electrical therapy of living tissue
US20040158289A1 (en) * 2002-11-30 2004-08-12 Girouard Steven D. Method and apparatus for cell and electrical therapy of living tissue
US7840263B2 (en) * 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
US7764995B2 (en) 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
US7828711B2 (en) * 2004-08-16 2010-11-09 Cardiac Pacemakers, Inc. Method and apparatus for modulating cellular growth and regeneration using ventricular assist device
US8060219B2 (en) * 2004-12-20 2011-11-15 Cardiac Pacemakers, Inc. Epicardial patch including isolated extracellular matrix with pacing electrodes
US7981065B2 (en) 2004-12-20 2011-07-19 Cardiac Pacemakers, Inc. Lead electrode incorporating extracellular matrix
CA2603857A1 (en) * 2005-03-31 2006-11-16 Mytogen, Inc. Treatment for heart disease
EP1885185A4 (de) 2005-05-09 2010-04-07 Mytogen Inc Zellkardiomyoplastie als begleittherapie bei herzpatienten
EP3532605A4 (de) 2016-10-26 2021-01-13 Sonic Master Limited Verbesserte erzeugung von muskelstammzellen und therapeutische verwendungen davon

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU624284B2 (en) * 1989-11-24 1992-06-04 Monash University Proliferative action of leukaemia inhibitory factor on satellite cells
WO1991012329A2 (en) * 1990-02-12 1991-08-22 Board Of Regents, The University Of Texas System Satellite cell proliferation in adult skeletal muscle
US5833978A (en) * 1995-03-16 1998-11-10 Universite Laval Method of in vitro preconditioning healthy donor's myoblasts before transplantation thereof in compatible patients suffering of recessive myopathies like muscular dystrophy, for improving transplantation success
US6284242B1 (en) * 1999-04-16 2001-09-04 Regents Of The University Of Michigan Method for enhancing myoblast migration and invasion in the context of gene therapy

Also Published As

Publication number Publication date
US20020012657A1 (en) 2002-01-31
US20020182193A1 (en) 2002-12-05
DE69737460T2 (de) 2008-04-10
EP0946713B1 (de) 2007-03-07
CA2269096C (en) 2009-12-15
AU4613397A (en) 1998-05-15
ATE356199T1 (de) 2007-03-15
US20070178077A1 (en) 2007-08-02
US7189391B2 (en) 2007-03-13
WO1998017784A1 (en) 1998-04-30
CA2269096A1 (en) 1998-04-30
EP0946713A1 (de) 1999-10-06

Similar Documents

Publication Publication Date Title
DE69737460D1 (de) Verfahren zur in vitro vorbehandlung von myoblasten in der transplantation
CA2339182A1 (en) Improvement of cardiac function by mesenchymal stem cell transplantation
DE69433174D1 (de) In vitro reifen von oozyten mit inhibitin/activin kombinationen
ATE345682T1 (de) In vitro verfahren zum einbringen von nukleinsäuren in eine zelle
WO2004069172A3 (en) Multilineage-inducible cells and uses thereof
EA200200698A1 (ru) Способ выделения рнк из фиксированных формалином и залитых в парафин образцов ткани
PT1526172E (pt) Processo para a replicação de vírus influenza em cultura celular e os vírus influenza que podem ser obtidos pelo processo
DK1115840T3 (da) Afstamningsspecifikke celler og progenitorceller
ATE430807T1 (de) Verfahren zur kultivierung von circovirus
AU6475186A (en) Process for separating motile sperm cells in vitro, fertilization method and penetration medium for sperm cells
DE69636545D1 (de) Gefrierkonservierte hepatocyten und verfahren für ihre herstellung
ATE258593T1 (de) Verfahren zur gefriertrocknung von verschiedenen mikroorganismen
DE60038630D1 (de) Verfahren zur ex vivo bildung von säugetier-knochen und dessen verwendungen
ATE222122T1 (de) Verfahren zur tötung von zielzellen in geernteten zellpopulationen mit hilfe von zwei immunotoxinen
CA2177043A1 (en) Hepatoblasts and method of isolating same
KR880007714A (ko) 구군 식물의 증식방법
DE69902397T2 (de) Neues verfahren zur kryokonservierung von pflanzen
ES2145845T3 (es) Procedimiento para el cultivo de hepatocitos bipolares adheridos.
DE68915568T2 (de) Verfahren zur Gewinnung der Protease von Endothia parasitica.
DE3854472T2 (de) Erhaltung der Viabilität von Mikroorganismen zur Anwendung in mikrobiellen Inokulantien.
DE69013425T2 (de) Pseudomonasmutant, yzh-Stamm und Verfahren zur Herstellung der 851yzh-Nährlösung mittels dieses Stammes.
DE60132466D1 (de) Verfahren zur kultivierung von menschlichen lungenmastzellen und deren anwendungen
ATE182365T1 (de) Verfahren zur herstellung von pilocarpin
ATE375717T1 (de) Verfahren zur inhibierung der abstossung von transplantaten
UA39348A (uk) Спосіб отримання позаклітинного дифтерійного антигена

Legal Events

Date Code Title Description
8364 No opposition during term of opposition