DE69738200D1 - Verwendung eines emulgatorsystems zur erhöhung des penetrationsflusses pharmazeutischer wirkstoffe - Google Patents

Verwendung eines emulgatorsystems zur erhöhung des penetrationsflusses pharmazeutischer wirkstoffe

Info

Publication number
DE69738200D1
DE69738200D1 DE69738200T DE69738200T DE69738200D1 DE 69738200 D1 DE69738200 D1 DE 69738200D1 DE 69738200 T DE69738200 T DE 69738200T DE 69738200 T DE69738200 T DE 69738200T DE 69738200 D1 DE69738200 D1 DE 69738200D1
Authority
DE
Germany
Prior art keywords
increasing
active substances
pharmaceutical active
emulsifier system
penetrating flow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69738200T
Other languages
English (en)
Other versions
DE69738200T2 (de
Inventor
Matthew T Scholz
Robert A Asmus
John C Hedenstrom
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3M Co
Original Assignee
Minnesota Mining and Manufacturing Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minnesota Mining and Manufacturing Co filed Critical Minnesota Mining and Manufacturing Co
Application granted granted Critical
Publication of DE69738200D1 publication Critical patent/DE69738200D1/de
Publication of DE69738200T2 publication Critical patent/DE69738200T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
DE69738200T 1997-01-09 1997-12-23 Verwendung eines emulgatorsystems zur erhöhung des penetrationsflusses pharmazeutischer wirkstoffe Expired - Lifetime DE69738200T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/781,097 US6019997A (en) 1997-01-09 1997-01-09 Hydroalcoholic compositions for transdermal penetration of pharmaceutical agents
US781097 1997-01-09
PCT/US1997/023483 WO1998030244A1 (en) 1997-01-09 1997-12-23 Hydroalcoholic compositions for transdermal penetration of pharmaceutical agents

Publications (2)

Publication Number Publication Date
DE69738200D1 true DE69738200D1 (de) 2007-11-22
DE69738200T2 DE69738200T2 (de) 2008-07-10

Family

ID=25121692

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69738200T Expired - Lifetime DE69738200T2 (de) 1997-01-09 1997-12-23 Verwendung eines emulgatorsystems zur erhöhung des penetrationsflusses pharmazeutischer wirkstoffe

Country Status (8)

Country Link
US (1) US6019997A (de)
EP (1) EP0957939B1 (de)
JP (1) JP2001508062A (de)
AU (1) AU738444B2 (de)
CA (1) CA2274565C (de)
DE (1) DE69738200T2 (de)
ES (1) ES2293667T3 (de)
WO (1) WO1998030244A1 (de)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2314272A1 (de) * 1995-06-22 2011-04-27 Minnesota Mining And Manufacturing Company Stabile alkoholisch-wässrige Zusammensetzung
US6623744B2 (en) * 1995-06-22 2003-09-23 3M Innovative Properties Company Stable hydroalcoholic compositions
US7566460B2 (en) * 1995-06-22 2009-07-28 3M Innovative Properties Company Stable hydroalcoholic compositions
CA2224798A1 (en) 1995-06-22 1997-01-09 Matthew T. Scholz Stable hydroalcoholic compositions
US6440980B1 (en) 1996-09-17 2002-08-27 Avanir Pharmaceuticals Synergistic inhibition of viral replication by long-chain hydrocarbons and nucleoside analogs
US6582711B1 (en) 1997-01-09 2003-06-24 3M Innovative Properties Company Hydroalcoholic compositions thickened using polymers
EP1094781B1 (de) * 1998-07-07 2008-07-02 Transdermal Technologies Inc. Zusammensetzungen für die schnelle und nicht-irritierende transdermale verabreichung von pharmazeutika and verfahren zur formuliering davon und ihren verabreichung
EP1105096B1 (de) * 1998-08-19 2003-10-29 Skyepharma Canada Inc. Injizierbare wässerige propofoldispersionen
CN1209108C (zh) * 1999-02-09 2005-07-06 株式会社三养社 一种经皮肤传递的止吐剂成份和含相同成份的制剂
KR100390870B1 (ko) * 1999-02-09 2003-07-10 주식회사 삼양사 경피투여용 항구토제 조성물 및 이를 포함하는 제제
US6679870B1 (en) * 1999-07-23 2004-01-20 Vasca, Inc. Methods and kits for locking and disinfecting implanted catheters
US6562368B2 (en) * 1999-12-16 2003-05-13 Dermatrends, Inc. Transdermal administration of oxybutynin using hydroxide-releasing agents as permeation enhancers
US6562369B2 (en) * 1999-12-16 2003-05-13 Dermatrends, Inc. Transdermal administration of androgenic drugs hydroxide-releasing agents as permeation enhancers
US6673363B2 (en) 1999-12-16 2004-01-06 Dermatrends, Inc. Transdermal and topical administration of local anesthetic agents using basic enhancers
US6645520B2 (en) * 1999-12-16 2003-11-11 Dermatrends, Inc. Transdermal administration of nonsteroidal anti-inflammatory drugs using hydroxide-releasing agents as permeation enhancers
US6586000B2 (en) * 1999-12-16 2003-07-01 Dermatrends, Inc. Hydroxide-releasing agents as skin permeation enhancers
US6565879B1 (en) 1999-12-16 2003-05-20 Dermatrends, Inc. Topical and transdermal administration of peptidyl drugs with hydroxide-releasing agents as skin permeation enhancers
US6719997B2 (en) 2000-06-30 2004-04-13 Dermatrends, Inc. Transdermal administration of pharmacologically active amines using hydroxide-releasing agents as permeation enhancers
US6562370B2 (en) 1999-12-16 2003-05-13 Dermatrends, Inc. Transdermal administration of steroid drugs using hydroxide-releasing agents as permeation enhancers
US6582724B2 (en) * 1999-12-16 2003-06-24 Dermatrends, Inc. Dual enhancer composition for topical and transdermal drug delivery
US6602912B2 (en) 2000-06-30 2003-08-05 Dermatrends, Inc. Transdermal administration of phenylpropanolamine
US20030104041A1 (en) * 1999-12-16 2003-06-05 Tsung-Min Hsu Transdermal and topical administration of drugs using basic permeation enhancers
US6558695B2 (en) 1999-12-16 2003-05-06 Dermatrends, Inc. Topical and transdermal administration of peptidyl drugs using hydroxide releasing agents as permeation enhancers
US20060121103A1 (en) * 2000-05-11 2006-06-08 Kenneth Kirby Transdermal delivery system
US20040092494A9 (en) * 2000-08-30 2004-05-13 Dudley Robert E. Method of increasing testosterone and related steroid concentrations in women
US20030139384A1 (en) * 2000-08-30 2003-07-24 Dudley Robert E. Method for treating erectile dysfunction and increasing libido in men
US6503894B1 (en) * 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
US20040002482A1 (en) * 2000-08-30 2004-01-01 Dudley Robert E. Androgen pharmaceutical composition and method for treating depression
SE0004750D0 (sv) * 2000-12-19 2000-12-19 Astrazeneca Ab Novel formulation
US7247315B2 (en) * 2001-08-17 2007-07-24 Lavipharm Laboratories Inc. Compositions and medical device for transdermal delivery of a drug and methods of making and using same
NO20014746D0 (no) * 2001-09-28 2001-09-28 Clas M Kjoelberg Smertelindrende middel
EP1436006A4 (de) * 2001-10-16 2006-06-07 Avanir Pharmaceuticals Virushemmung mit n-docosanol
DE10154324A1 (de) * 2001-11-06 2003-08-07 Merz Pharma Gmbh & Co Kgaa Topisch applizierbare Zusammensetzungen mit externer Wirkstoffdepotbildung, deren Herstellung sowie deren Verwendung
UA80964C2 (en) * 2002-03-15 2007-11-26 Unimed Pharmaceuticals Inc Method for treating depression and kit therefor
MY139721A (en) * 2002-04-19 2009-10-30 Cpex Pharmaceuticals Inc Pharmaceutical composition
US20040018163A1 (en) * 2002-04-29 2004-01-29 Wei Yu Cosmetic compositions comprising at least one dimethicone, at least one linear hydrocarbon wax and at least one compatibilizing agent
US7192599B2 (en) * 2002-06-03 2007-03-20 Mmp, Inc. Mattifying oil-in-water emulsion
US20050037040A1 (en) * 2003-08-13 2005-02-17 Moshe Arkin Topical compositions of urea and ammonium lactate
US20050042182A1 (en) * 2003-08-13 2005-02-24 Moshe Arkin Topical compositions of urea
US20050036953A1 (en) * 2003-08-13 2005-02-17 Moshe Arkin Topical compositions of ammonium lactate
US20050025833A1 (en) * 2003-07-16 2005-02-03 Chaim Aschkenasy Pharmaceutical composition and method for transdermal drug delivery
US20050042268A1 (en) * 2003-07-16 2005-02-24 Chaim Aschkenasy Pharmaceutical composition and method for transdermal drug delivery
US20050020552A1 (en) * 2003-07-16 2005-01-27 Chaim Aschkenasy Pharmaceutical composition and method for transdermal drug delivery
EA200600666A1 (ru) * 2003-09-29 2006-10-27 Этена Хелткеа Инк. Гелеобразные и пенистые композиции с высоким содержанием спирта
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
CA2580329C (en) 2004-09-13 2015-01-06 Chrono Therapeutics Inc. Biosynchronous transdermal drug delivery
DE102004062775A1 (de) 2004-12-21 2006-06-29 Stockhausen Gmbh Alkoholischer Pumpschaum
EA012308B1 (ru) 2005-03-07 2009-08-28 Деб Уорлдвайд Хелткер Инк. Пенящиеся композиции с высоким содержанием спирта и поверхностно-активными веществами на основе силикона
US20070088012A1 (en) * 2005-04-08 2007-04-19 Woun Seo Method of treating or preventing type-2 diabetes
WO2006127905A2 (en) 2005-05-24 2006-11-30 Chrono Therapeutics, Inc. Portable drug delivery device
US7651990B2 (en) * 2005-06-13 2010-01-26 3M Innovative Properties Company Foamable alcohol compositions comprising alcohol and a silicone surfactant, systems and methods of use
US20070065494A1 (en) * 2005-08-03 2007-03-22 Watson Laboratories, Inc. Formulations and Methods for Enhancing the Transdermal Penetration of a Drug
JP5584415B2 (ja) 2005-10-12 2014-09-03 ユニメッド・ファーマシューティカルズ・エルエルシー 改良したテストステロンゲル製剤及び使用の方法
US20070148101A1 (en) * 2005-12-28 2007-06-28 Marcia Snyder Foamable alcoholic composition
US8167847B2 (en) 2006-06-22 2012-05-01 Excelsior Medical Corporation Antiseptic cap and antiseptic cap equipped plunger and syringe barrel assembly
EP1905302A1 (de) 2006-09-30 2008-04-02 Bayer CropScience AG Suspensionskonzentrate
US20080146672A1 (en) * 2006-12-08 2008-06-19 Denton Marcia Marye Topical Eutectic Anesthetic Composition for Oral or Dermal Tissue
US8354116B2 (en) * 2007-06-18 2013-01-15 Biochemics, Inc. Bifunctional synthetic molecules
HU227970B1 (en) 2007-07-10 2012-07-30 Egis Gyogyszergyar Nyrt Pharmaceutical compositions containing silicones of high volatility
US7862877B2 (en) * 2007-11-20 2011-01-04 Basic Electronics, Inc. Sanitary wrap
US20100272784A1 (en) 2009-04-28 2010-10-28 3M Innovative Properties Company Water-soluble pressure sensitive adhesives
DE102010004950A1 (de) * 2010-01-18 2011-07-21 Remis Gesellschaft für Entwicklung und Vertrieb von technischen Elementen mbH, 50829 Kühlregal mit Türvorrichtung
US9296904B2 (en) 2010-12-20 2016-03-29 3M Innovative Properties Company Coating compositions comprising non-ionic surfactant exhibiting reduced fingerprint visibility
US8742022B2 (en) 2010-12-20 2014-06-03 3M Innovative Properties Company Coating compositions comprising non-ionic surfactant exhibiting reduced fingerprint visibility
WO2013006643A1 (en) 2011-07-06 2013-01-10 The Parkinson's Institute Compositions and methods for treatment of symptoms in parkinson's disease patients
US9441135B2 (en) 2012-06-19 2016-09-13 3M Innovative Properties Company Additive comprising low surface energy group and hydroxyl groups and coating compositions
JP6218820B2 (ja) 2012-06-19 2017-10-25 スリーエム イノベイティブ プロパティズ カンパニー 低い指紋視認性を呈する重合性非イオン性界面活性剤を含むコーティング組成物
US11154535B2 (en) 2012-07-31 2021-10-26 Egis Pharmaceuticals Plc Transdermal formulation containing COX inhibitors
US10045935B2 (en) 2012-07-31 2018-08-14 Egis Pharmaceuticals Plc Transdermal formulation containing COX inhibitors
US9638452B2 (en) * 2012-09-12 2017-05-02 Celltronix Method and scalable devices for hyper-fast cooling and warming
US10105487B2 (en) 2013-01-24 2018-10-23 Chrono Therapeutics Inc. Optimized bio-synchronous bioactive agent delivery system
US8785426B1 (en) 2013-12-13 2014-07-22 Upsher-Smith Laboratories, Inc. Testosterone gel compositions and related methods
JP2017508808A (ja) * 2014-03-17 2017-03-30 ジー・エフ・エス．コーポレーション．エー・ユー・エス．ピー・ティー・ワイ．エル・ティー・ディーＧｆｓ Ｃｏｒｐｏｒａｔｉｏｎ Ａｕｓ Ｐｔｙ Ｌｔｄ 抗菌性除菌剤組成物およびその使用
US10213586B2 (en) 2015-01-28 2019-02-26 Chrono Therapeutics Inc. Drug delivery methods and systems
AU2016228779A1 (en) 2015-03-12 2017-09-07 Chrono Therapeutics Inc. Craving input and support system
US11285306B2 (en) 2017-01-06 2022-03-29 Morningside Venture Investments Limited Transdermal drug delivery devices and methods
JP7420797B2 (ja) 2018-05-29 2024-01-23 モーニングサイド ベンチャー インベストメンツ リミテッド 薬剤送達の方法及びシステム
CN109700601B (zh) * 2019-02-02 2022-04-22 天津嘉氏堂科技有限公司 一种水胶体硅敷料贴

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2054989A (en) * 1933-12-30 1936-09-22 Us Ind Alcohol Co Compositions for application to the human skin
US2153143A (en) * 1938-01-28 1939-04-04 Eastman Kodak Co Nondiscoloring, liquid antiseptic soap
US2678902A (en) * 1950-11-06 1954-05-18 Colgate Palmolive Co Hand lotion
US3131152A (en) * 1960-06-13 1964-04-28 Allied Chem Foam producing formulations
US3131154A (en) * 1961-10-25 1964-04-28 Allied Chem Foam producing compositions
US3395214A (en) * 1964-01-09 1968-07-30 Scholl Mfg Co Inc Antiperspirant composition providing a readily collapsible sprayable foam
US3415939A (en) * 1965-06-22 1968-12-10 Roberts David Matte cosmetic cream composition
US3840465A (en) * 1970-11-18 1974-10-08 Texaco Inc Aerosol foam composition
US4006218A (en) * 1974-07-08 1977-02-01 Johnson & Johnson Potentiated medicaments
JPS5729213B2 (de) * 1974-11-12 1982-06-21
GB1527781A (en) * 1975-10-08 1978-10-11 Djuro C Anti-inflammatory composition
US4202881A (en) * 1976-06-18 1980-05-13 Wella Ag Hair shampoo and conditioning lotion
FR2406438A1 (fr) * 1977-10-19 1979-05-18 Messac Leon Composition corporelle tonifiante, raffermissante et amincissante pour applications locales
US4199564A (en) * 1978-09-22 1980-04-22 Masti-Kure Products Company, Inc. Film-forming alcoholic microbicidal teat dip and method of use thereof
DE3064347D1 (en) * 1979-02-06 1983-09-01 Procter & Gamble Soap bars
US4511486A (en) * 1981-11-02 1985-04-16 Richardson-Vicks Inc. Method of cleaning dentures using aerated foams
US4464293A (en) * 1982-04-12 1984-08-07 Dobrin Robert J Liquid cleaner-disinfectant composition for use in wiping down dental operatories
US4478853A (en) * 1982-05-17 1984-10-23 S. C. Johnson & Son, Inc. Skin conditioning composition
US4542012A (en) * 1982-07-02 1985-09-17 Minnesota Mining And Manufacturing Company Film-forming composition containing an antimicrobial agent and methods
US4752612A (en) * 1983-07-01 1988-06-21 Nitto Electrical Industrial Co., Ltd. Method and percutaneously administering physiologically active agents using an alcohol adjuvant and a solvent
US4559226A (en) * 1983-09-06 1985-12-17 Bernel Chemical Company Inc. Self-emulsifying alkoxylate esters
WO1985001876A1 (en) * 1983-10-24 1985-05-09 Lockley Services Pty. Ltd. Foamable biocide composition
US4501834A (en) * 1983-12-22 1985-02-26 Colgate-Palmolive Company Gels formed from anionic and cationic polymers
DE3406497A1 (de) * 1984-02-23 1985-09-05 Mueller Bernhard Willi Werner Hochdisperse pharmazeutische mehrkomponentensysteme und verfahren zu ihrer herstellung
DE3416777C2 (de) * 1984-05-07 1986-11-20 Gödecke AG, 1000 Berlin Pharmazeutische topische Zubereitungen
US4584192A (en) * 1984-06-04 1986-04-22 Minnesota Mining & Manufacturing Company Film-forming composition containing an antimicrobial agent and methods of use
IL77224A (en) * 1984-12-12 1989-09-10 Euro Celtique Sa Antibacterial cream
US4695453A (en) * 1985-01-24 1987-09-22 Henkel Corporation Thickened alcoholic antimicrobial compositions
US4806262A (en) * 1985-08-14 1989-02-21 The Procter & Gamble Company Nonlathering cleansing mousse with skin conditioning benefits
CA1299098C (en) * 1985-10-28 1992-04-21 John H. White Alcohol-based antimicrobial compositions
AU600269B2 (en) * 1986-05-08 1990-08-09 Sterling Drug Inc. Disinfectant wipe
US4831023A (en) * 1986-06-27 1989-05-16 Thames Pharmacal Co., Inc. Water washable vehicles for topical use
JPH0678217B2 (ja) * 1986-09-18 1994-10-05 花王株式会社 乳化型毛髪化粧料
DE3632030C2 (de) * 1986-09-20 1995-01-05 Wella Ag Verdicktes kosmetisches Mittel zur Festigung der Frisur
JPH0755911B2 (ja) * 1987-02-26 1995-06-14 株式会社資生堂 経皮吸収促進剤及びこれを含有する皮膚外用製剤
JPS63230640A (ja) * 1987-03-19 1988-09-27 Shiseido Co Ltd 経皮吸収促進剤及びこれを含有する皮膚外用製剤
JPS63230641A (ja) * 1987-03-19 1988-09-27 Shiseido Co Ltd 経皮吸収促進剤及びこれを含有する皮膚外用製剤
KR900007659B1 (ko) * 1987-02-23 1990-10-18 시세이도 가부시끼가이샤 경피 흡수촉진제 및 이를 함유하는 피부외용 제제
JPH0759519B2 (ja) * 1987-02-23 1995-06-28 株式会社資生堂 経皮吸収促進剤及びこれを含有する皮膚外用製剤
US4792415A (en) * 1987-04-13 1988-12-20 Merck & Co., Inc. Quaternary ammonium salts of anionic gums
US4917895A (en) * 1987-11-02 1990-04-17 Alza Corporation Transdermal drug delivery device
US4931282A (en) * 1987-11-25 1990-06-05 Minnesota Mining And Manufacturing Company Pressure-sensitive medical sealant
US5225473A (en) * 1987-11-25 1993-07-06 Minnesota Mining And Manufacturing Company Pressure-sensitive adhesives
US5223261A (en) * 1988-02-26 1993-06-29 Riker Laboratories, Inc. Transdermal estradiol delivery system
US4883660A (en) * 1988-10-17 1989-11-28 Thames Pharmacal Co., Inc. Gel bases for pharmaceutical compositions
US5232691A (en) * 1989-04-26 1993-08-03 Lemole Gerald M Protective gel composition
US4956170A (en) * 1989-06-28 1990-09-11 S. C. Johnson & Son, Inc. Skin moisturizing/conditioning antimicrobial alcoholic gels
US4957908A (en) * 1990-01-08 1990-09-18 Olin Corporation Chitosan pyrithione as antimicrobial agent useful in personal care products
FR2657617B1 (fr) * 1990-01-31 1994-03-25 Oreal Emulsions huile-dans-eau a base de silicones insolubles et d'un agent emulsionnant du type acide ether carboxylique polyoxyalkylene, et leur application en cosmetique et en dermatologie.
GB9005523D0 (en) * 1990-03-12 1990-05-09 Unilever Plc Cosmetic composition
US5149719A (en) * 1990-04-27 1992-09-22 Minnesota Mining And Manufacturing Company Composition for transdermal penetration of medicaments
US5128123A (en) * 1991-02-08 1992-07-07 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Clear cosmetic sticks
US5167950A (en) * 1991-03-28 1992-12-01 S. C. Johnson & Son High alcohol content aerosol antimicrobial mousse
US5164107A (en) * 1991-04-25 1992-11-17 Becton, Dickinson And Company Chlorhexidine composition useful in a surgical scrub
FR2677982B1 (fr) * 1991-06-24 1993-09-24 Oreal Composes polyfluoroalkylthiopoly(ethylimidazolium), procede de preparation et leur utilisation comme agents biocides.
GB9114255D0 (en) * 1991-07-02 1991-08-21 Unilever Plc Cosmetic composition
US5180061A (en) * 1991-09-09 1993-01-19 Becton, Dickinson And Company Stable iodophor in polyurethane foam
EG20380A (en) * 1991-10-16 1999-02-28 Richardson Vicks Inc Enhanced skin penetration system for improved topical delivery of drugs
US5276079A (en) * 1991-11-15 1994-01-04 Minnesota Mining And Manufacturing Company Pressure-sensitive poly(n-vinyl lactam) adhesive composition and method for producing and using same
AU4387693A (en) * 1992-06-10 1994-01-04 Alberto-Culver Company Emulsifier salt compositions for applying silicone oil to hair
US5460620A (en) * 1992-07-31 1995-10-24 Creative Products Resource, Inc. Method of applying in-tandem applicator pads for transdermal delivery of a therapeutic agent
US5484597A (en) * 1993-07-30 1996-01-16 Chesebrough-Pond's Usa Co. Clear hydroalcholic cosmetic microemulsions
US5334388A (en) * 1993-09-15 1994-08-02 Becton, Dickinson And Company Antimicrobial drying substrate
US5512199A (en) * 1993-11-02 1996-04-30 Becton Dickinson And Company Hand wipe solution
EP0745389A4 (de) * 1994-02-18 1998-01-14 Inst Advanced Skin Res Inc Mittel zur topischen anwendung
FR2717075B1 (fr) * 1994-03-14 1996-04-05 Oreal Gel aqueux de maquillage à organopolysiloxane.
CA2151774C (en) * 1994-06-27 1999-04-06 Minh Quang Hoang Skin disinfecting formulations
JP2878130B2 (ja) * 1994-09-16 1999-04-05 株式会社大阪製薬 消毒剤組成物
US5585092A (en) * 1995-04-13 1996-12-17 The Procter & Gamble Company Gel deodorant compositions
CA2224798A1 (en) * 1995-06-22 1997-01-09 Matthew T. Scholz Stable hydroalcoholic compositions

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CA2274565A1 (en) 1998-07-16
WO1998030244A1 (en) 1998-07-16
DE69738200T2 (de) 2008-07-10
CA2274565C (en) 2008-04-08
EP0957939A1 (de) 1999-11-24
US6019997A (en) 2000-02-01
EP0957939B1 (de) 2007-10-10
AU738444B2 (en) 2001-09-20
JP2001508062A (ja) 2001-06-19
AU5709898A (en) 1998-08-03
ES2293667T3 (es) 2008-03-16

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