DE69739165D1 - Matrix mit verzögerter freisetzung für hochdosierte unlösliche arzneistoffe - Google Patents

Matrix mit verzögerter freisetzung für hochdosierte unlösliche arzneistoffe

Info

Publication number
DE69739165D1
DE69739165D1 DE69739165T DE69739165T DE69739165D1 DE 69739165 D1 DE69739165 D1 DE 69739165D1 DE 69739165 T DE69739165 T DE 69739165T DE 69739165 T DE69739165 T DE 69739165T DE 69739165 D1 DE69739165 D1 DE 69739165D1
Authority
DE
Germany
Prior art keywords
medicaments
insulated
matrix
delayed release
highly dosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69739165T
Other languages
English (en)
Inventor
Anand R Baichwal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Penwest Pharmaceuticals Co
Original Assignee
Penwest Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Penwest Pharmaceuticals Co filed Critical Penwest Pharmaceuticals Co
Application granted granted Critical
Publication of DE69739165D1 publication Critical patent/DE69739165D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE69739165T 1996-07-08 1997-07-08 Matrix mit verzögerter freisetzung für hochdosierte unlösliche arzneistoffe Expired - Lifetime DE69739165D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2133596P 1996-07-08 1996-07-08
PCT/US1997/013331 WO1998001117A1 (en) 1996-07-08 1997-07-08 Sustained release matrix for high-dose insoluble drugs

Publications (1)

Publication Number Publication Date
DE69739165D1 true DE69739165D1 (de) 2009-01-29

Family

ID=21803631

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69739165T Expired - Lifetime DE69739165D1 (de) 1996-07-08 1997-07-08 Matrix mit verzögerter freisetzung für hochdosierte unlösliche arzneistoffe

Country Status (12)

Country Link
US (4) US6093420A (de)
EP (1) EP0859603B1 (de)
JP (1) JP3148256B2 (de)
KR (1) KR100321489B1 (de)
AT (1) ATE417604T1 (de)
AU (1) AU695734B2 (de)
CA (1) CA2231195C (de)
DE (1) DE69739165D1 (de)
ES (1) ES2322405T3 (de)
IL (1) IL123505A (de)
MX (1) MX9801835A (de)
WO (1) WO1998001117A1 (de)

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US6689386B2 (en) 2004-02-10
ES2322405T3 (es) 2009-06-19
IL123505A0 (en) 1998-10-30
AU695734B2 (en) 1998-08-20
EP0859603A4 (de) 2006-05-24
IL123505A (en) 2004-12-15
CA2231195A1 (en) 1998-01-15
KR100321489B1 (ko) 2002-10-09
US6245355B1 (en) 2001-06-12
AU3818397A (en) 1998-02-02
ATE417604T1 (de) 2009-01-15
US20040121012A1 (en) 2004-06-24
US6093420A (en) 2000-07-25
JPH10511407A (ja) 1998-11-04
EP0859603A1 (de) 1998-08-26
WO1998001117A1 (en) 1998-01-15
CA2231195C (en) 2003-01-21
EP0859603B1 (de) 2008-12-17
JP3148256B2 (ja) 2001-03-19
MX9801835A (es) 1998-08-30
KR19990044486A (ko) 1999-06-25
US20010021392A1 (en) 2001-09-13

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