DE69801025T2 - Polyurethan Biomaterialien zur Verwendung in medizinischen Vorrichtungen - Google Patents

Polyurethan Biomaterialien zur Verwendung in medizinischen Vorrichtungen

Info

Publication number
DE69801025T2
DE69801025T2 DE69801025T DE69801025T DE69801025T2 DE 69801025 T2 DE69801025 T2 DE 69801025T2 DE 69801025 T DE69801025 T DE 69801025T DE 69801025 T DE69801025 T DE 69801025T DE 69801025 T2 DE69801025 T2 DE 69801025T2
Authority
DE
Germany
Prior art keywords
medical devices
polyurethane biomaterials
biomaterials
polyurethane
medical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69801025T
Other languages
English (en)
Other versions
DE69801025D1 (de
Inventor
Edward Didomenico
David L Miller
Michael E Benz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medtronic Inc
Original Assignee
Medtronic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic Inc filed Critical Medtronic Inc
Application granted granted Critical
Publication of DE69801025D1 publication Critical patent/DE69801025D1/de
Publication of DE69801025T2 publication Critical patent/DE69801025T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72—Polyisocyanates or polyisothiocyanates
    • C08G18/74—Polyisocyanates or polyisothiocyanates cyclic
    • C08G18/75—Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic
    • C08G18/751—Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic containing only one cycloaliphatic ring
    • C08G18/752—Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic containing only one cycloaliphatic ring containing at least one isocyanate or isothiocyanate group linked to the cycloaliphatic ring by means of an aliphatic group
    • C08G18/757—Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic containing only one cycloaliphatic ring containing at least one isocyanate or isothiocyanate group linked to the cycloaliphatic ring by means of an aliphatic group containing at least two isocyanate or isothiocyanate groups linked to the cycloaliphatic ring by means of an aliphatic group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/04—Macromolecular materials
    • A61L29/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/30—Low-molecular-weight compounds
    • C08G18/32—Polyhydroxy compounds; Polyamines; Hydroxyamines
    • C08G18/3203—Polyhydroxy compounds
    • C08G18/3206—Polyhydroxy compounds aliphatic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/30—Low-molecular-weight compounds
    • C08G18/32—Polyhydroxy compounds; Polyamines; Hydroxyamines
    • C08G18/3203—Polyhydroxy compounds
    • C08G18/3212—Polyhydroxy compounds containing cycloaliphatic groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/30—Low-molecular-weight compounds
    • C08G18/38—Low-molecular-weight compounds having heteroatoms other than oxygen
    • C08G18/3855—Low-molecular-weight compounds having heteroatoms other than oxygen having sulfur
    • C08G18/3863—Low-molecular-weight compounds having heteroatoms other than oxygen having sulfur containing groups having sulfur atoms between two carbon atoms, the sulfur atoms being directly linked to carbon atoms or other sulfur atoms
    • C08G18/3865—Low-molecular-weight compounds having heteroatoms other than oxygen having sulfur containing groups having sulfur atoms between two carbon atoms, the sulfur atoms being directly linked to carbon atoms or other sulfur atoms containing groups having one sulfur atom between two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/30—Low-molecular-weight compounds
    • C08G18/38—Low-molecular-weight compounds having heteroatoms other than oxygen
    • C08G18/3855—Low-molecular-weight compounds having heteroatoms other than oxygen having sulfur
    • C08G18/3876—Low-molecular-weight compounds having heteroatoms other than oxygen having sulfur containing mercapto groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72—Polyisocyanates or polyisothiocyanates
    • C08G18/74—Polyisocyanates or polyisothiocyanates cyclic
    • C08G18/75—Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic
    • C08G18/751—Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic containing only one cycloaliphatic ring
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72—Polyisocyanates or polyisothiocyanates
    • C08G18/74—Polyisocyanates or polyisothiocyanates cyclic
    • C08G18/75—Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic
    • C08G18/751—Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic containing only one cycloaliphatic ring
    • C08G18/752—Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic containing only one cycloaliphatic ring containing at least one isocyanate or isothiocyanate group linked to the cycloaliphatic ring by means of an aliphatic group
DE69801025T 1997-04-30 1998-04-30 Polyurethan Biomaterialien zur Verwendung in medizinischen Vorrichtungen Expired - Lifetime DE69801025T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/846,337 US6111052A (en) 1997-04-30 1997-04-30 Polyurethane and polyurea biomaterials for use in medical devices

Publications (2)

Publication Number Publication Date
DE69801025D1 DE69801025D1 (de) 2001-08-09
DE69801025T2 true DE69801025T2 (de) 2002-05-16

Family

ID=25297610

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69801025T Expired - Lifetime DE69801025T2 (de) 1997-04-30 1998-04-30 Polyurethan Biomaterialien zur Verwendung in medizinischen Vorrichtungen

Country Status (3)

Country Link
US (5) US6111052A (de)
EP (1) EP0875519B1 (de)
DE (1) DE69801025T2 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6111052A (en) * 1997-04-30 2000-08-29 Medtronic, Inc. Polyurethane and polyurea biomaterials for use in medical devices
US6915168B1 (en) * 1997-05-08 2005-07-05 Michael D. Benz Medical devices containing segmented polyurethane biomaterials
US6366819B1 (en) * 2000-10-03 2002-04-02 Medtronic, Inc. Biostable small French lead
US6999819B2 (en) * 2001-08-31 2006-02-14 Medtronic, Inc. Implantable medical electrical stimulation lead fixation method and apparatus
US7101956B2 (en) * 2001-11-14 2006-09-05 Medtronic, Inc. Compounds containing quaternary carbons, medical devices, and methods
WO2003042273A1 (en) * 2001-11-14 2003-05-22 Medtronic, Inc. Compounds containing quaternary carbons, medical devices, and methods
AU2003265446A1 (en) * 2002-08-13 2004-02-25 Medtronic, Inc. Active agent delivery system including a hydrophilic polymer, medical device, and method
CA2494188A1 (en) * 2002-08-13 2004-02-19 Medtronic, Inc. Active agent delivery system including a hydrophobic cellulose derivative
AU2003258209A1 (en) * 2002-08-13 2004-02-25 Medtronic, Inc. Active agent delivery systems, medical devices, and methods
ATE459380T1 (de) * 2002-08-13 2010-03-15 Medtronic Inc Darreichungssysteme von wirkstoffen mit poly(ethylene-co(meth)akrylate, medizinische vorrichtung und verfahren
US20040033251A1 (en) * 2002-08-13 2004-02-19 Medtronic, Inc. Active agent delivery system including a polyurethane, medical device, and method
DE60333566D1 (de) * 2002-08-13 2010-09-09 Medtronic Inc Medizinische vorrichtung mit verbesserter haftung zwischen einem polymeren berzug und einem substrat
US6984700B2 (en) 2002-09-17 2006-01-10 Medtronic, Inc. Compounds containing silicon-containing groups, medical devices, and methods
AU2003270704A1 (en) * 2002-09-17 2004-04-08 Medtronic, Inc. Polymers with soft segments containing silane-containing groups, medical devices, and methods
CA2499347A1 (en) 2002-09-17 2004-04-01 Medtronic, Inc. Compounds containing quaternary carbons and silicon-containing groups, medical devices, and methods
CA2503193A1 (en) * 2002-10-22 2004-05-06 The Biomerix Corporation Method and system for intravesicular delivery of therapeutic agents
CN1717263A (zh) * 2002-10-23 2006-01-04 比奥米瑞斯公司 动脉瘤的治疗装置和方法
CN101193623A (zh) * 2003-05-15 2008-06-04 柏尔迈瑞克斯公司 可植入的网状弹性基质的制造和应用
CA2535346A1 (en) * 2003-08-13 2005-03-03 Medtronic, Inc. Active agent delivery systems, including a single layer of a miscible polymer blend, medical devices, and methods
CA2535345A1 (en) * 2003-08-13 2005-03-03 Medtronic, Inc. Active agent delivery systems including a miscible polymer blend, medical devices, and methods
US7763077B2 (en) * 2003-12-24 2010-07-27 Biomerix Corporation Repair of spinal annular defects and annulo-nucleoplasty regeneration
WO2005105881A1 (ja) * 2004-04-30 2005-11-10 Canon Finetech Inc. 酸化防止剤およびそれを適用した被記録媒体
US20060057394A1 (en) * 2004-09-15 2006-03-16 Specialty Products, Inc. System and method for coating a substrate
US8771294B2 (en) 2004-11-26 2014-07-08 Biomerix Corporation Aneurysm treatment devices and methods
US20070162131A1 (en) * 2004-12-23 2007-07-12 Friedman Craig D Repair of spinal annular defects
US20060178497A1 (en) * 2005-02-04 2006-08-10 Clemson University And Thordon Bearings, Inc. Implantable biomedical devices including biocompatible polyurethanes
JP2009504331A (ja) * 2005-08-15 2009-02-05 シネコー・エルエルシー リードの固定と摘出
US8182647B2 (en) 2007-07-23 2012-05-22 Cohera Medical, Inc. Hydrophilic biodegradable adhesives
US9327168B2 (en) 2010-12-22 2016-05-03 Acushnet Company Methods for making polyurea and polyurethane polymers and golf balls prepared therefrom
US8487063B2 (en) * 2010-12-22 2013-07-16 Acushnet Company Methods for making polyurea polymer and products prepared therefrom
WO2013151656A1 (en) 2012-04-02 2013-10-10 Medtronic, Inc. Medical leads
US10258802B2 (en) * 2015-11-20 2019-04-16 Cardiac Pacemakers, Inc. Delivery devices and methods for leadless cardiac devices
US10882945B2 (en) 2018-03-26 2021-01-05 Medtronic, Inc. Modified polyisobutylene-based polymers, methods of making, and medical devices
US20190292327A1 (en) 2018-03-26 2019-09-26 Medtronic, Inc. Poly(ether-carbonate)-based polymers and medical devices

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5071918A (de) * 1973-11-02 1975-06-14
US3996627A (en) * 1975-09-22 1976-12-14 American Optical Corporation Artificial intraocular lens
US4191818A (en) * 1975-10-25 1980-03-04 Basf Wyandotte Corporation Process for preparing heat-resistant polyurethane elastomers having no secondary softening range
DE2547866A1 (de) * 1975-10-25 1977-05-05 Basf Ag Waermebestaendige polyurethanelastomere
DE2734574A1 (de) * 1977-07-30 1979-02-08 Bayer Ag Thiogruppenhaltige polyurethankunststoffe
JPS5566917A (en) * 1978-11-14 1980-05-20 Toyo Tire & Rubber Co Ltd Manufacture of non-yellowing integral polyurethane foam
US4430471A (en) * 1979-04-06 1984-02-07 American Cyanamid Company Elastomers derived from thiodiethanol having reduced odor
US4285073A (en) * 1980-02-11 1981-08-25 Thermo Electron Corporation Keratoprosthetic polyurethane
US4289854A (en) 1980-06-20 1981-09-15 Monsanto Company Cell culture method and apparatus
US4349656A (en) * 1980-07-23 1982-09-14 American Cyanamid Company Thiodiethanol based polyurethane elastomers having improved dynamic properties and method for production thereof
DE3318730A1 (de) * 1983-05-21 1984-11-22 Akzo Gmbh, 5600 Wuppertal Biokompatible polyurethane
DE3329775A1 (de) * 1983-08-18 1985-02-28 Bayer Ag, 5090 Leverkusen Thermoplastische polyurethane hoher waermestandfestigkeit auf basis von naphthylendiisocyanat, verfahren zu ihrer herstellung und ihre verwendung
US4780522A (en) * 1984-04-11 1988-10-25 Mitsui Toatsu Chemicals, Incorporated Sulfur-containing polyurethane base lens resin
GB8428109D0 (en) * 1984-11-07 1984-12-12 Biocompatibles Ltd Biocompatible surfaces
US4596836A (en) * 1985-01-14 1986-06-24 The Goodyear Tire & Rubber Company Stabilizing urethanes with antioxidants
US4851009A (en) * 1985-12-16 1989-07-25 Corvita Corporation Crack prevention of implanted prostheses
US5040544A (en) * 1988-02-16 1991-08-20 Medtronic, Inc. Medical electrical lead and method of manufacture
US4873308A (en) * 1988-09-30 1989-10-10 Medtronic, Inc. Biostable, segmented aliphatic polyurethanes and process therefor
US5001210A (en) * 1988-09-30 1991-03-19 Medtronic, Inc. Method for producing polyurethanes from poly-(hydroxyalkyl urethanes)
US5247004A (en) * 1989-02-03 1993-09-21 Ppg Industries, Inc. Polymeric-containing compositions with improved oxidative stability
CA1336110C (en) * 1989-02-03 1995-06-27 Robert Gregory Swisher Polymeric-containing compositions with improved oxidative stability
JPH03296517A (ja) * 1990-04-16 1991-12-27 Terumo Corp 医用ポリウレタンおよびその製造方法
EP0461072B1 (de) * 1990-06-07 1998-07-29 Ciba SC Holding AG Verfahren zur Herstellung von Polyurethanstoffen unter Verwendung von spezifischen Stabilisatorsystemen
CA2038605C (en) * 1990-06-15 2000-06-27 Leonard Pinchuk Crack-resistant polycarbonate urethane polymer prostheses and the like
US5238006A (en) * 1991-06-24 1993-08-24 Medtronic, Inc. Apnea stimulation lead
US5375609A (en) * 1992-01-27 1994-12-27 Medtronic, Inc. Pacing lead insulator
US5318572A (en) * 1992-06-02 1994-06-07 Siemens Pacesetter, Inc. High efficiency tissue stimulating and signal sensing electrode
US5480421A (en) * 1992-10-30 1996-01-02 Medtronic, Inc. Lead with stylet capture member
CA2121660A1 (en) * 1993-05-10 1994-11-11 Gregory J. Mann Biostable polyurethane and medical article therefrom
JPH07258599A (ja) * 1994-03-23 1995-10-09 Tonen Corp 高耐候性アクリル樹脂系塗料用組成物
WO1996029102A1 (en) * 1995-03-17 1996-09-26 Regents Of The University Of Minnesota Biocompatible materials
US6008296A (en) * 1995-04-19 1999-12-28 Optima, Inc. Optical terpolymer of polyisocyanate, polythiol and polyene monomers
US5925724A (en) * 1995-06-23 1999-07-20 Shell Oil Company Use of polydiene diols in thermoplastic polyurethanes
US5864001A (en) * 1996-10-16 1999-01-26 Shell Oil Company Polyurethanes made with polydiene diols, diisocyanates, and dimer diol chain extender
US6111052A (en) * 1997-04-30 2000-08-29 Medtronic, Inc. Polyurethane and polyurea biomaterials for use in medical devices

Also Published As

Publication number Publication date
US6149678A (en) 2000-11-21
US5986034A (en) 1999-11-16
US6437076B1 (en) 2002-08-20
DE69801025D1 (de) 2001-08-09
EP0875519B1 (de) 2001-07-04
US6111052A (en) 2000-08-29
US6437075B1 (en) 2002-08-20
EP0875519A1 (de) 1998-11-04

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Representative=s name: KUDLEK & GRUNERT PATENTANWAELTE PARTNERSCHAFT, 803