DE69804832D1 - Dosierungsform zur verabreichung von aerosolen - Google Patents

Dosierungsform zur verabreichung von aerosolen

Info

Publication number
DE69804832D1
DE69804832D1 DE69804832T DE69804832T DE69804832D1 DE 69804832 D1 DE69804832 D1 DE 69804832D1 DE 69804832 T DE69804832 T DE 69804832T DE 69804832 T DE69804832 T DE 69804832T DE 69804832 D1 DE69804832 D1 DE 69804832D1
Authority
DE
Germany
Prior art keywords
medicament
network
solid state
aqueous vehicle
kit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69804832T
Other languages
English (en)
Other versions
DE69804832T2 (de
Inventor
P Redmon
A West
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sunovion Pharmaceuticals Inc
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sepracor Inc filed Critical Sepracor Inc
Publication of DE69804832D1 publication Critical patent/DE69804832D1/de
Application granted granted Critical
Publication of DE69804832T2 publication Critical patent/DE69804832T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2093—Containers having several compartments for products to be mixed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202—Separating means
    • A61J1/2041—Separating means having removable plugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/005—Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
DE1998604832 1997-10-08 1998-10-07 Dosierungsform zur verabreichung von aerosolen Expired - Fee Related DE69804832T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6136397P 1997-10-08 1997-10-08
PCT/US1998/021115 WO1999017754A1 (en) 1997-10-08 1998-10-07 Dosage form for aerosol administration

Publications (2)

Publication Number Publication Date
DE69804832D1 true DE69804832D1 (de) 2002-05-16
DE69804832T2 DE69804832T2 (de) 2002-11-07

Family

ID=22035318

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1998604832 Expired - Fee Related DE69804832T2 (de) 1997-10-08 1998-10-07 Dosierungsform zur verabreichung von aerosolen

Country Status (12)

Country Link
US (1) US6161536A (de)
EP (1) EP1021172B1 (de)
JP (1) JP2001518494A (de)
KR (1) KR20010024453A (de)
AT (1) ATE215820T1 (de)
AU (1) AU743174B2 (de)
CA (1) CA2301569A1 (de)
DE (1) DE69804832T2 (de)
ES (1) ES2175799T3 (de)
HU (1) HUP0003917A3 (de)
NO (1) NO20001747D0 (de)
WO (1) WO1999017754A1 (de)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5758637A (en) 1995-08-31 1998-06-02 Aerogen, Inc. Liquid dispensing apparatus and methods
US6427682B1 (en) * 1995-04-05 2002-08-06 Aerogen, Inc. Methods and apparatus for aerosolizing a substance
US6040344A (en) * 1996-11-11 2000-03-21 Sepracor Inc. Formoterol process
US6679249B2 (en) * 1998-04-21 2004-01-20 Pneumoflex Systems, L.L.C. Apparatus for treatment of chronic obstructive pulmonary disease and associated method
US6235177B1 (en) 1999-09-09 2001-05-22 Aerogen, Inc. Method for the construction of an aperture plate for dispensing liquid droplets
AU2273301A (en) * 1999-12-23 2001-07-09 Robert E. Coifman Methods and formulations for the efficient delivery of water-insoluble drugs by nebulizer
US7971588B2 (en) 2000-05-05 2011-07-05 Novartis Ag Methods and systems for operating an aerosol generator
US8336545B2 (en) 2000-05-05 2012-12-25 Novartis Pharma Ag Methods and systems for operating an aerosol generator
US7914470B2 (en) 2001-01-12 2011-03-29 Celleration, Inc. Ultrasonic method and device for wound treatment
US8235919B2 (en) 2001-01-12 2012-08-07 Celleration, Inc. Ultrasonic method and device for wound treatment
EP1353667A1 (de) 2001-01-25 2003-10-22 Bristol-Myers Squibb Company Parenterale zusammensetzungen enthaltend epothilon-analoge
ITMI20010428A1 (it) * 2001-03-02 2002-09-02 Chemo Breath S A Composizioni ad uso inalatorio a base di formoterolo
US6667344B2 (en) * 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
US20030055026A1 (en) 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
EG24184A (en) * 2001-06-15 2008-10-08 Otsuka Pharma Co Ltd Dry powder inhalation system for transpulmonary
WO2003026556A2 (en) * 2001-09-12 2003-04-03 Ivax Corporation Breath-enhanced ultrasonic nebulizer and dedicated unit dose ampoule
RU2279292C2 (ru) * 2001-10-24 2006-07-10 Пари Гмбх Набор для приготовления фармацевтической композиции
WO2003057291A1 (en) 2002-01-07 2003-07-17 Aerogen, Inc. Devices and methods for nebulizing fluids for inhalation
US7677467B2 (en) 2002-01-07 2010-03-16 Novartis Pharma Ag Methods and devices for aerosolizing medicament
EP1474196B1 (de) 2002-01-15 2016-08-17 Novartis AG Verfahren und systeme zum bedienen eines aerosol-erzeugers
AU2003256253A1 (en) 2002-05-20 2003-12-02 Aerogen, Inc. Aerosol for medical treatment and methods
US20040045546A1 (en) 2002-09-05 2004-03-11 Peirce Management, Llc Pharmaceutical delivery system for oral inhalation through nebulization consisting of inert substrate impregnated with substance (S) to be solubilized or suspended prior to use
AU2003293833B2 (en) 2002-12-12 2009-10-01 Covis Pharma B.V. Combination medicament
WO2004110460A1 (en) 2003-06-13 2004-12-23 Altana Pharma Ag Formoterol and ciclesonide combination
TWI359675B (en) * 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
US8616195B2 (en) 2003-07-18 2013-12-31 Novartis Ag Nebuliser for the production of aerosolized medication
JP2007531743A (ja) * 2004-04-05 2007-11-08 セプラコア インコーポレーテッド 他の薬剤と組合せた（ｒ，ｒ）−ホルモテロール
US7946291B2 (en) 2004-04-20 2011-05-24 Novartis Ag Ventilation systems and methods employing aerosol generators
RS55114B1 (sr) 2005-05-18 2016-12-30 Raptor Pharmaceuticals Inc Aerosolizovani fluorohinoloni i njihove upotrebe
US8546423B2 (en) 2005-05-18 2013-10-01 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
CN101208123B (zh) 2005-05-25 2012-09-19 亚罗擎公司 振动系统和方法
US7785277B2 (en) 2005-06-23 2010-08-31 Celleration, Inc. Removable applicator nozzle for ultrasound wound therapy device
US7713218B2 (en) * 2005-06-23 2010-05-11 Celleration, Inc. Removable applicator nozzle for ultrasound wound therapy device
US9101949B2 (en) 2005-08-04 2015-08-11 Eilaz Babaev Ultrasonic atomization and/or seperation system
WO2007059620A1 (en) * 2005-11-23 2007-05-31 Feanny Stephen J Method for administering formoterol using a nebulizer
US7858609B2 (en) 2005-11-28 2010-12-28 Marinus Pharmaceuticals Solid ganaxolone formulations and methods for the making and use thereof
DE102005057685A1 (de) * 2005-12-01 2007-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator und Speicher für eine trockene Arzneimittelformulierung sowie diesbezügliche Verfahren und Verwendung
US20080230053A1 (en) 2006-09-15 2008-09-25 Board Of Regents, The University Of Texas System Pulse drug nebulization systems, formulations therefore, and methods of use
CA2669815A1 (en) * 2006-11-28 2008-06-05 Marinus Pharmaceuticals Nanoparticulate formulations and methods for the making and use thereof
US8491521B2 (en) 2007-01-04 2013-07-23 Celleration, Inc. Removable multi-channel applicator nozzle
US9849254B2 (en) * 2007-05-15 2017-12-26 Caddo Medical Technologies Llc Pre-filled, small-volume nebulizer
WO2009088553A1 (en) 2007-10-22 2009-07-16 Board Of Regents, The University Of Texas System Dry powder drug delivery formulations, methods of use, and devices therefore
ES2809177T3 (es) 2008-10-07 2021-03-03 Horizon Orphan Llc Inhalación de levofloxacino para reducir la inflamación pulmonar
AU2009302478B2 (en) 2008-10-07 2015-09-03 Horizon Orphan Llc Aerosol fluoroquinolone formulations for improved pharmacokinetics
US8534031B2 (en) * 2008-12-30 2013-09-17 Bausch & Lomb Incorporated Packaging solutions
CA2938650C (en) 2009-09-04 2018-01-09 Raptor Pharmaceuticals Inc. Use of aerosolized levofloxacin for treating cystic fibrosis
JP5494186B2 (ja) * 2010-04-28 2014-05-14 オムロンヘルスケア株式会社 ネブライザキットおよびネブライザ
EP2670242B1 (de) 2011-01-31 2022-03-16 Avalyn Pharma Inc. Aerosolförmige pirfenidon- und pyridonanalogverbindungen und verwendungen davon
GB201111250D0 (en) * 2011-07-01 2011-08-17 Univ Central Lancashire Method of producing a nebuliser composition
ES2959198T3 (es) 2012-07-24 2024-02-21 Avalyn Pharma Inc Compuestos análogos de pirfenidona y piridona en aerosol
US9662345B2 (en) * 2013-06-14 2017-05-30 Professional Compounding Centers Of America Antibiotic composition for inhalation and irrigation
CA3172586A1 (en) 2013-07-31 2015-02-05 Avalyn Pharma Inc. Aerosol imatininb compounds and uses thereof
US11224767B2 (en) 2013-11-26 2022-01-18 Sanuwave Health, Inc. Systems and methods for producing and delivering ultrasonic therapies for wound treatment and healing
AU2017311412B2 (en) 2016-08-11 2023-05-18 Ovid Therapeutics Inc. Methods and compositions for treatment of epileptic disorders
WO2018103636A1 (en) * 2016-12-05 2018-06-14 Microbase Technology Corp. Aerosol generating apparatus with replaceable parts
WO2019110099A1 (en) 2017-12-06 2019-06-13 Qrumpharma Inc. Inhalable clofazimine formulation
CA3095450A1 (en) * 2018-04-05 2019-10-10 Royal Melbourne Institute Of Technology Multi surface acoustic nebuliser
JP7377259B2 (ja) 2018-08-23 2023-11-09 マンカインド コーポレイション クロファジミンの組成物、それを含む組合せ、それを調製するためのプロセス、それを含む使用及び方法
WO2020118142A1 (en) 2018-12-07 2020-06-11 Marinus Pharmaceuticals, Inc. Ganaxolone for use in prophylaxis and treatment of pospartum depression
WO2020123336A1 (en) 2018-12-13 2020-06-18 Qrumpharma Inc. Compositions of bedaquiline, combinations comprising them, processes for their preparation, uses and methods of treatment comprising them
CA3142101A1 (en) 2019-06-04 2020-12-10 Thirty Holdings Limited Methods and compositions for generating nitric oxide and uses thereof
EP3980032A1 (de) 2019-06-04 2022-04-13 Thirty Respiratory Limited Verfahren und zusammensetzungen zur erzeugung von stickoxid und verwendungen davon zur abgabe von stickoxid über die atemwege
WO2021026124A1 (en) 2019-08-05 2021-02-11 Marinus Pharmaceuticals, Inc. Ganaxolone for use in treatment of status epilepticus
CN114828889A (zh) 2019-12-06 2022-07-29 马瑞纳斯制药公司 用于治疗结节性硬化症的加奈索酮
GB2586301B (en) 2020-04-07 2021-08-25 Splash Tm Gmbh Stable-Foam inhalation Device and Cartridge
WO2021214440A1 (en) 2020-04-23 2021-10-28 Thirty Respiratory Limited Nitric oxide or nitric oxide releasing compositions for use in treating sars-cov and sars-cov-2
BR112022021436A2 (pt) 2020-04-23 2023-01-17 Thirty Respiratory Ltd Métodos e composições para tratamento e combate da tuberculose
WO2021247542A2 (en) 2020-06-01 2021-12-09 Advent Therapeutics, Inc. Pharmaceutical compositions comprising insoluble active ingredients
WO2022240897A1 (en) 2021-05-10 2022-11-17 Sepelo Therapeutics, Llc Pharmaceutical composition comprising delafloxacin for administration into the lung
WO2023028364A1 (en) 2021-08-27 2023-03-02 Sepelo Therapeutics, Llc Targeted compositions and uses therof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3898338A (en) * 1971-10-07 1975-08-05 Mead Johnson & Co 1,4-Bis-acylpiperazine mucolytic process
IE45770B1 (en) * 1976-10-06 1982-11-17 Wyeth John & Brother Ltd Pharmaceutical dosage forms
GB1548022A (en) * 1976-10-06 1979-07-04 Wyeth John & Brother Ltd Pharmaceutial dosage forms
US4089432A (en) * 1977-05-06 1978-05-16 The Upjohn Company Vial and closure
US4194640A (en) * 1977-05-06 1980-03-25 The Upjohn Company Vial and closure
US4274543A (en) * 1978-01-23 1981-06-23 The Upjohn Company Vial and closure structure
US4267925A (en) * 1979-10-01 1981-05-19 The Upjohn Company Closure for large-volume vial
US4258845A (en) * 1979-11-20 1981-03-31 The Upjohn Company Activator closure for two-compartment vial
US4331233A (en) * 1980-05-30 1982-05-25 The Upjohn Company Activation closure for vial
RU2109509C1 (ru) * 1991-12-24 1998-04-27 Яманути Фармасьютикал Ко., Лтд. Композиция для буккального введения лекарственного средства и способ ее получения
US5215079A (en) * 1992-05-19 1993-06-01 Armstrong Pharmaceuticals, Inc. Single dose metered dose inhaler for delivery of vaccines and other drugs
US5586550A (en) * 1995-08-31 1996-12-24 Fluid Propulsion Technologies, Inc. Apparatus and methods for the delivery of therapeutic liquids to the respiratory system
AU2322097A (en) * 1996-03-27 1997-10-17 Ortho Pharmaceutical Corporation Lyophilized pulmonary surfactant peptide compositions

Also Published As

Publication number Publication date
HUP0003917A3 (en) 2001-04-28
ATE215820T1 (de) 2002-04-15
HUP0003917A2 (en) 2001-03-28
AU9687998A (en) 1999-04-27
JP2001518494A (ja) 2001-10-16
CA2301569A1 (en) 1999-04-15
ES2175799T3 (es) 2002-11-16
EP1021172A1 (de) 2000-07-26
DE69804832T2 (de) 2002-11-07
AU743174B2 (en) 2002-01-17
NO20001747L (no) 2000-04-05
WO1999017754A1 (en) 1999-04-15
KR20010024453A (ko) 2001-03-26
NO20001747D0 (no) 2000-04-05
US6161536A (en) 2000-12-19
EP1021172B1 (de) 2002-04-10

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee