DE69804832T2 - Dosierungsform zur verabreichung von aerosolen - Google Patents
Dosierungsform zur verabreichung von aerosolenInfo
- Publication number
- DE69804832T2 DE69804832T2 DE1998604832 DE69804832T DE69804832T2 DE 69804832 T2 DE69804832 T2 DE 69804832T2 DE 1998604832 DE1998604832 DE 1998604832 DE 69804832 T DE69804832 T DE 69804832T DE 69804832 T2 DE69804832 T2 DE 69804832T2
- Authority
- DE
- Germany
- Prior art keywords
- medicament
- network
- solid state
- aqueous vehicle
- kit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2093—Containers having several compartments for products to be mixed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/202—Separating means
- A61J1/2041—Separating means having removable plugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/005—Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6136397P | 1997-10-08 | 1997-10-08 | |
PCT/US1998/021115 WO1999017754A1 (en) | 1997-10-08 | 1998-10-07 | Dosage form for aerosol administration |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69804832D1 DE69804832D1 (de) | 2002-05-16 |
DE69804832T2 true DE69804832T2 (de) | 2002-11-07 |
Family
ID=22035318
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE1998604832 Expired - Fee Related DE69804832T2 (de) | 1997-10-08 | 1998-10-07 | Dosierungsform zur verabreichung von aerosolen |
Country Status (12)
Country | Link |
---|---|
US (1) | US6161536A (de) |
EP (1) | EP1021172B1 (de) |
JP (1) | JP2001518494A (de) |
KR (1) | KR20010024453A (de) |
AT (1) | ATE215820T1 (de) |
AU (1) | AU743174B2 (de) |
CA (1) | CA2301569A1 (de) |
DE (1) | DE69804832T2 (de) |
ES (1) | ES2175799T3 (de) |
HU (1) | HUP0003917A3 (de) |
NO (1) | NO20001747D0 (de) |
WO (1) | WO1999017754A1 (de) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102005057685A1 (de) * | 2005-12-01 | 2007-06-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Inhalator und Speicher für eine trockene Arzneimittelformulierung sowie diesbezügliche Verfahren und Verwendung |
US11206872B2 (en) | 2020-04-07 | 2021-12-28 | Consumernext Labs Gmbh | Stable-foam dispensing device and cartridge |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5758637A (en) | 1995-08-31 | 1998-06-02 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
US6427682B1 (en) * | 1995-04-05 | 2002-08-06 | Aerogen, Inc. | Methods and apparatus for aerosolizing a substance |
US6040344A (en) * | 1996-11-11 | 2000-03-21 | Sepracor Inc. | Formoterol process |
US6679249B2 (en) * | 1998-04-21 | 2004-01-20 | Pneumoflex Systems, L.L.C. | Apparatus for treatment of chronic obstructive pulmonary disease and associated method |
US6235177B1 (en) | 1999-09-09 | 2001-05-22 | Aerogen, Inc. | Method for the construction of an aperture plate for dispensing liquid droplets |
AU2273301A (en) * | 1999-12-23 | 2001-07-09 | Robert E. Coifman | Methods and formulations for the efficient delivery of water-insoluble drugs by nebulizer |
US8336545B2 (en) | 2000-05-05 | 2012-12-25 | Novartis Pharma Ag | Methods and systems for operating an aerosol generator |
US7971588B2 (en) | 2000-05-05 | 2011-07-05 | Novartis Ag | Methods and systems for operating an aerosol generator |
US8235919B2 (en) | 2001-01-12 | 2012-08-07 | Celleration, Inc. | Ultrasonic method and device for wound treatment |
US7914470B2 (en) | 2001-01-12 | 2011-03-29 | Celleration, Inc. | Ultrasonic method and device for wound treatment |
SK8552003A3 (en) | 2001-01-25 | 2004-06-08 | Bristol Myers Squibb Co | Parenteral formulation containing epothilone analogs |
ITMI20010428A1 (it) * | 2001-03-02 | 2002-09-02 | Chemo Breath S A | Composizioni ad uso inalatorio a base di formoterolo |
US6667344B2 (en) * | 2001-04-17 | 2003-12-23 | Dey, L.P. | Bronchodilating compositions and methods |
US20030055026A1 (en) | 2001-04-17 | 2003-03-20 | Dey L.P. | Formoterol/steroid bronchodilating compositions and methods of use thereof |
EG24184A (en) | 2001-06-15 | 2008-10-08 | Otsuka Pharma Co Ltd | Dry powder inhalation system for transpulmonary |
CA2466214A1 (en) * | 2001-09-12 | 2003-04-03 | Ivax U.K., Ltd. | Breath-enhanced ultrasonic nebulizer and dedicated unit dose ampoule |
CA2464250C (en) * | 2001-10-24 | 2008-08-05 | Frank-Christophe Lintz | Kit for the preparation of a pharmaceutical composition |
US7677467B2 (en) | 2002-01-07 | 2010-03-16 | Novartis Pharma Ag | Methods and devices for aerosolizing medicament |
CA2472644C (en) | 2002-01-07 | 2013-11-05 | Aerogen, Inc. | Devices and methods for nebulizing fluids for inhalation |
ES2603067T3 (es) | 2002-01-15 | 2017-02-23 | Novartis Ag | Métodos y sistemas para hacer funcionar un generador de aerosol |
EP1509259B1 (de) | 2002-05-20 | 2016-04-20 | Novartis AG | Gerät zur bereitstellung eines aerosols für die medizinische behandlung und verfahren |
US20040045546A1 (en) | 2002-09-05 | 2004-03-11 | Peirce Management, Llc | Pharmaceutical delivery system for oral inhalation through nebulization consisting of inert substrate impregnated with substance (S) to be solubilized or suspended prior to use |
DK1572217T3 (da) | 2002-12-12 | 2008-12-15 | Nycomed Gmbh | Kombinationsmedikament af R,R-formoterol og ciclesonid |
JP2006527237A (ja) | 2003-06-13 | 2006-11-30 | アルタナ ファルマ アクチエンゲゼルシャフト | ホルモテロールと及びシクレソニドの組合せ物 |
TWI359675B (en) * | 2003-07-10 | 2012-03-11 | Dey L P | Bronchodilating β-agonist compositions |
US8616195B2 (en) | 2003-07-18 | 2013-12-31 | Novartis Ag | Nebuliser for the production of aerosolized medication |
WO2005097095A1 (en) * | 2004-04-05 | 2005-10-20 | Sepracor Inc. | (r,r)-formoterol in combination with other pharmacological agents |
US7946291B2 (en) | 2004-04-20 | 2011-05-24 | Novartis Ag | Ventilation systems and methods employing aerosol generators |
CA2900093C (en) | 2005-05-18 | 2018-11-13 | Mpex Pharmaceuticals, Inc. | Aerosolized fluoroquinolones and uses thereof |
US8524735B2 (en) | 2005-05-18 | 2013-09-03 | Mpex Pharmaceuticals, Inc. | Aerosolized fluoroquinolones and uses thereof |
JP5064383B2 (ja) | 2005-05-25 | 2012-10-31 | エアロジェン,インコーポレイテッド | 振動システムと方法 |
US7785277B2 (en) | 2005-06-23 | 2010-08-31 | Celleration, Inc. | Removable applicator nozzle for ultrasound wound therapy device |
US7713218B2 (en) * | 2005-06-23 | 2010-05-11 | Celleration, Inc. | Removable applicator nozzle for ultrasound wound therapy device |
US9101949B2 (en) | 2005-08-04 | 2015-08-11 | Eilaz Babaev | Ultrasonic atomization and/or seperation system |
US20080319079A1 (en) * | 2005-11-23 | 2008-12-25 | Feanny Stephen J | Method for Administering Formoterol Using a Nebulizer |
US8022054B2 (en) | 2005-11-28 | 2011-09-20 | Marinus Pharmaceuticals | Liquid ganaxolone formulations and methods for the making and use thereof |
US20080230053A1 (en) | 2006-09-15 | 2008-09-25 | Board Of Regents, The University Of Texas System | Pulse drug nebulization systems, formulations therefore, and methods of use |
EP2101735A2 (de) * | 2006-11-28 | 2009-09-23 | Marinus Pharmaceuticals, Inc. | Nanoteilchenförmige formulierungen und verfahren zur herstellung und verwendung |
US8491521B2 (en) | 2007-01-04 | 2013-07-23 | Celleration, Inc. | Removable multi-channel applicator nozzle |
US9849254B2 (en) * | 2007-05-15 | 2017-12-26 | Caddo Medical Technologies Llc | Pre-filled, small-volume nebulizer |
US8597616B2 (en) | 2007-10-22 | 2013-12-03 | Board Of Regents Of The University Of Texas System | Dry powder drug delivery formulations, methods of use, and devices therefore |
SI2346509T1 (sl) | 2008-10-07 | 2020-08-31 | Horizon Orphan Llc | Inhalacija levofloksacina za zmanjšanje vnetja pljuč |
LT2344129T (lt) | 2008-10-07 | 2018-05-10 | Horizon Orphan Llc | Aerozolinės fluorchinolono kompozicijos, skirtos farmakokinetikų pagerinimui |
US8534031B2 (en) * | 2008-12-30 | 2013-09-17 | Bausch & Lomb Incorporated | Packaging solutions |
DK2473170T3 (da) | 2009-09-04 | 2019-08-12 | Horizon Orphan Llc | Anvendelse af aerosoliseret levofloxacin til behandling af cystisk fibrose |
JP5494186B2 (ja) * | 2010-04-28 | 2014-05-14 | オムロンヘルスケア株式会社 | ネブライザキットおよびネブライザ |
EP4059499A1 (de) | 2011-01-31 | 2022-09-21 | Avalyn Pharma Inc. | Aerosolförmige pirfenidon- und pyridonanalogverbindungen und verwendungen davon |
GB201111250D0 (en) * | 2011-07-01 | 2011-08-17 | Univ Central Lancashire | Method of producing a nebuliser composition |
EP2877164B1 (de) | 2012-07-24 | 2023-07-05 | Avalyn Pharma Inc. | Aerosolpirfenidon und pyridonanalogverbindungen |
US9662345B2 (en) * | 2013-06-14 | 2017-05-30 | Professional Compounding Centers Of America | Antibiotic composition for inhalation and irrigation |
EP3027026A4 (de) | 2013-07-31 | 2017-05-03 | Windward Pharma, Inc. | Aerosoltyrosinkinasehemmer-verbindungen und verwendungen davon |
AU2014355072A1 (en) | 2013-11-26 | 2016-06-02 | Alliqua Biomedical, Inc. | Systems and methods for producing and delivering ultrasonic therapies for wound treatment and healing |
BR112019002538A2 (pt) | 2016-08-11 | 2019-05-21 | Ovid Therapeutics Inc. | uso de uma composição farmacêutica compreendendo um modulador alostérico, uso de uma composição farmacêutica compreendendo garboxadol ou um sal farmaceuticamente aceitável do mesmo, e composição farmacêutica para a administração parenteral |
CN109414717A (zh) * | 2016-12-05 | 2019-03-01 | 微邦科技股份有限公司 | 具有可替换部分的气雾产生装置 |
WO2019110099A1 (en) | 2017-12-06 | 2019-06-13 | Qrumpharma Inc. | Inhalable clofazimine formulation |
CN112135692A (zh) * | 2018-04-05 | 2020-12-25 | 皇家墨尔本理工大学 | 多表面声波雾化器 |
EP3840737A1 (de) | 2018-08-23 | 2021-06-30 | MannKind Corporation | Clofazimin-zusammensetzungen, diese enthaltende kombinationen, verfahren zu ihrer herstellung, ihre verwendungen und verfahren damit |
US11266662B2 (en) | 2018-12-07 | 2022-03-08 | Marinus Pharmaceuticals, Inc. | Ganaxolone for use in prophylaxis and treatment of postpartum depression |
WO2020123336A1 (en) | 2018-12-13 | 2020-06-18 | Qrumpharma Inc. | Compositions of bedaquiline, combinations comprising them, processes for their preparation, uses and methods of treatment comprising them |
WO2020245574A1 (en) | 2019-06-04 | 2020-12-10 | Thirty Respiratory Limited | Methods and compositions for generating nitric oxide and uses thereof to deliver nitric oxide via the respiratory tract |
CN114206325A (zh) | 2019-06-04 | 2022-03-18 | 三十控股有限公司 | 用于生成一氧化氮的方法和组合物及其用途 |
CA3145923A1 (en) | 2019-08-05 | 2021-02-11 | David Czekai | Ganaxolone for use in treatment of status epilepticus |
MX2022006014A (es) | 2019-12-06 | 2022-06-22 | Marinus Pharmaceuticals Inc | Ganaxolona para uso en el tratamiento del complejo de esclerosis tuberosa. |
EP4138795A1 (de) | 2020-04-23 | 2023-03-01 | Thirty Respiratory Limited | Stickoxid oder stickoxid freisetzende zusammensetzungen zur verwendung bei der behandlung von sars-cov und sars-cov-2 |
WO2021214439A1 (en) | 2020-04-23 | 2021-10-28 | Thirty Respiratory Limited | Methods and compositions for treating and combatting tuberculosis |
KR20230054611A (ko) | 2020-06-01 | 2023-04-25 | 애드벤트 테라퓨틱스 인크. | 불용성 활성 성분을 포함하는 약제학적 조성물 |
WO2022240897A1 (en) | 2021-05-10 | 2022-11-17 | Sepelo Therapeutics, Llc | Pharmaceutical composition comprising delafloxacin for administration into the lung |
WO2023028364A1 (en) | 2021-08-27 | 2023-03-02 | Sepelo Therapeutics, Llc | Targeted compositions and uses therof |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3898338A (en) * | 1971-10-07 | 1975-08-05 | Mead Johnson & Co | 1,4-Bis-acylpiperazine mucolytic process |
IE45770B1 (en) * | 1976-10-06 | 1982-11-17 | Wyeth John & Brother Ltd | Pharmaceutical dosage forms |
GB1548022A (en) * | 1976-10-06 | 1979-07-04 | Wyeth John & Brother Ltd | Pharmaceutial dosage forms |
US4194640A (en) * | 1977-05-06 | 1980-03-25 | The Upjohn Company | Vial and closure |
US4089432A (en) * | 1977-05-06 | 1978-05-16 | The Upjohn Company | Vial and closure |
US4274543A (en) * | 1978-01-23 | 1981-06-23 | The Upjohn Company | Vial and closure structure |
US4267925A (en) * | 1979-10-01 | 1981-05-19 | The Upjohn Company | Closure for large-volume vial |
US4258845A (en) * | 1979-11-20 | 1981-03-31 | The Upjohn Company | Activator closure for two-compartment vial |
US4331233A (en) * | 1980-05-30 | 1982-05-25 | The Upjohn Company | Activation closure for vial |
WO1993012769A1 (en) * | 1991-12-24 | 1993-07-08 | Yamanouchi Pharmaceutical Co., Ltd. | Intrabuccally disintegrating preparation and production thereof |
US5215079A (en) * | 1992-05-19 | 1993-06-01 | Armstrong Pharmaceuticals, Inc. | Single dose metered dose inhaler for delivery of vaccines and other drugs |
US5586550A (en) * | 1995-08-31 | 1996-12-24 | Fluid Propulsion Technologies, Inc. | Apparatus and methods for the delivery of therapeutic liquids to the respiratory system |
AU2322097A (en) * | 1996-03-27 | 1997-10-17 | Ortho Pharmaceutical Corporation | Lyophilized pulmonary surfactant peptide compositions |
-
1998
- 1998-10-07 AT AT98950974T patent/ATE215820T1/de not_active IP Right Cessation
- 1998-10-07 CA CA 2301569 patent/CA2301569A1/en not_active Abandoned
- 1998-10-07 KR KR1020007003759A patent/KR20010024453A/ko not_active Application Discontinuation
- 1998-10-07 JP JP2000514626A patent/JP2001518494A/ja active Pending
- 1998-10-07 WO PCT/US1998/021115 patent/WO1999017754A1/en not_active Application Discontinuation
- 1998-10-07 ES ES98950974T patent/ES2175799T3/es not_active Expired - Lifetime
- 1998-10-07 AU AU96879/98A patent/AU743174B2/en not_active Ceased
- 1998-10-07 HU HU0003917A patent/HUP0003917A3/hu unknown
- 1998-10-07 EP EP98950974A patent/EP1021172B1/de not_active Expired - Lifetime
- 1998-10-07 US US09/168,216 patent/US6161536A/en not_active Expired - Fee Related
- 1998-10-07 DE DE1998604832 patent/DE69804832T2/de not_active Expired - Fee Related
-
2000
- 2000-04-05 NO NO20001747A patent/NO20001747D0/no not_active Application Discontinuation
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102005057685A1 (de) * | 2005-12-01 | 2007-06-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Inhalator und Speicher für eine trockene Arzneimittelformulierung sowie diesbezügliche Verfahren und Verwendung |
US11206872B2 (en) | 2020-04-07 | 2021-12-28 | Consumernext Labs Gmbh | Stable-foam dispensing device and cartridge |
Also Published As
Publication number | Publication date |
---|---|
AU9687998A (en) | 1999-04-27 |
KR20010024453A (ko) | 2001-03-26 |
WO1999017754A1 (en) | 1999-04-15 |
NO20001747L (no) | 2000-04-05 |
ES2175799T3 (es) | 2002-11-16 |
AU743174B2 (en) | 2002-01-17 |
JP2001518494A (ja) | 2001-10-16 |
US6161536A (en) | 2000-12-19 |
HUP0003917A2 (en) | 2001-03-28 |
ATE215820T1 (de) | 2002-04-15 |
EP1021172A1 (de) | 2000-07-26 |
EP1021172B1 (de) | 2002-04-10 |
DE69804832D1 (de) | 2002-05-16 |
HUP0003917A3 (en) | 2001-04-28 |
CA2301569A1 (en) | 1999-04-15 |
NO20001747D0 (no) | 2000-04-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |