DE69807747D1 - Tablette mit instant- und verzögerte freisetzung von einen oder mehrere wirkstoffe - Google Patents

Tablette mit instant- und verzögerte freisetzung von einen oder mehrere wirkstoffe

Info

Publication number
DE69807747D1
DE69807747D1 DE69807747T DE69807747T DE69807747D1 DE 69807747 D1 DE69807747 D1 DE 69807747D1 DE 69807747 T DE69807747 T DE 69807747T DE 69807747 T DE69807747 T DE 69807747T DE 69807747 D1 DE69807747 D1 DE 69807747D1
Authority
DE
Germany
Prior art keywords
instant
tablet
active substances
delayed release
delayed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69807747T
Other languages
English (en)
Other versions
DE69807747T2 (de
Inventor
Olivier Saslawski
Laurence Orlando
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Application granted granted Critical
Publication of DE69807747D1 publication Critical patent/DE69807747D1/de
Publication of DE69807747T2 publication Critical patent/DE69807747T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
DE69807747T 1997-12-23 1998-12-11 Tablette mit instant- und verzögerte freisetzung von einen oder mehrere wirkstoffe Expired - Lifetime DE69807747T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9716402A FR2772615B1 (fr) 1997-12-23 1997-12-23 Comprime multicouche pour la liberation instantanee puis prolongee de substances actives
PCT/EP1998/008100 WO1999033448A1 (en) 1997-12-23 1998-12-11 Tablet for instant and prolonged release of one or more active substances

Publications (2)

Publication Number Publication Date
DE69807747D1 true DE69807747D1 (de) 2002-10-10
DE69807747T2 DE69807747T2 (de) 2003-06-12

Family

ID=9515042

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69807747T Expired - Lifetime DE69807747T2 (de) 1997-12-23 1998-12-11 Tablette mit instant- und verzögerte freisetzung von einen oder mehrere wirkstoffe

Country Status (24)

Country Link
US (1) US6372255B1 (de)
EP (1) EP1041972B1 (de)
JP (1) JP4451563B2 (de)
KR (1) KR100574207B1 (de)
CN (1) CN1163220C (de)
AR (1) AR017897A1 (de)
AT (1) ATE223207T1 (de)
AU (1) AU743195B2 (de)
BR (1) BR9814345A (de)
CA (1) CA2316277C (de)
CZ (1) CZ291884B6 (de)
DE (1) DE69807747T2 (de)
DK (1) DK1041972T3 (de)
ES (1) ES2182397T3 (de)
FR (1) FR2772615B1 (de)
HU (1) HU226069B1 (de)
ID (1) ID26313A (de)
NO (1) NO20003289L (de)
PT (1) PT1041972E (de)
RU (1) RU2212885C2 (de)
SK (1) SK283236B6 (de)
UA (1) UA55503C2 (de)
WO (1) WO1999033448A1 (de)
ZA (1) ZA9811799B (de)

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CN1283110A (zh) 2001-02-07
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EP1041972A1 (de) 2000-10-11
ATE223207T1 (de) 2002-09-15
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PT1041972E (pt) 2003-01-31
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CA2316277A1 (en) 1999-07-08
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AR017897A1 (es) 2001-10-24
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AU2160699A (en) 1999-07-19
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