DE69809913T2 - Die herstellung von mikrostrukturen zur verwendung in tests - Google Patents

Die herstellung von mikrostrukturen zur verwendung in tests

Info

Publication number
DE69809913T2
DE69809913T2 DE69809913T DE69809913T DE69809913T2 DE 69809913 T2 DE69809913 T2 DE 69809913T2 DE 69809913 T DE69809913 T DE 69809913T DE 69809913 T DE69809913 T DE 69809913T DE 69809913 T2 DE69809913 T2 DE 69809913T2
Authority
DE
Germany
Prior art keywords
production
microstructures
tests
applying
onto
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69809913T
Other languages
English (en)
Other versions
DE69809913D1 (de
Inventor
Bernadette Yon-Hin
James Mccann
Saji-Cambridge Sensors L Eapen
Robin Lowe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cambridge Sensors Ltd
Original Assignee
Cambridge Sensors Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cambridge Sensors Ltd filed Critical Cambridge Sensors Ltd
Publication of DE69809913D1 publication Critical patent/DE69809913D1/de
Application granted granted Critical
Publication of DE69809913T2 publication Critical patent/DE69809913T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C1/00—Manufacture or treatment of devices or systems in or on a substrate
    • B81C1/00015—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems
    • B81C1/00023—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems without movable or flexible elements
    • B81C1/00119—Arrangement of basic structures like cavities or channels, e.g. suitable for microfluidic systems
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B01L7/525—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41M—PRINTING, DUPLICATING, MARKING, OR COPYING PROCESSES; COLOUR PRINTING
    • B41M1/00—Inking and printing with a printer's forme
    • B41M1/12—Stencil printing; Silk-screen printing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41M—PRINTING, DUPLICATING, MARKING, OR COPYING PROCESSES; COLOUR PRINTING
    • B41M3/00—Printing processes to produce particular kinds of printed work, e.g. patterns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00783—Laminate assemblies, i.e. the reactor comprising a stack of plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00819—Materials of construction
    • B01J2219/00831—Glass
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00819—Materials of construction
    • B01J2219/00833—Plastic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00891—Feeding or evacuation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00905—Separation
    • B01J2219/00909—Separation using filters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2203/00—Basic microelectromechanical structures
    • B81B2203/03—Static structures
    • B81B2203/0323—Grooves
    • B81B2203/0338—Channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C2201/00—Manufacture or treatment of microstructural devices or systems
    • B81C2201/01—Manufacture or treatment of microstructural devices or systems in or on a substrate
    • B81C2201/0174—Manufacture or treatment of microstructural devices or systems in or on a substrate for making multi-layered devices, film deposition or growing
    • B81C2201/0183—Selective deposition
    • B81C2201/0184—Digital lithography, e.g. using an inkjet print-head
DE69809913T 1997-07-18 1998-07-20 Die herstellung von mikrostrukturen zur verwendung in tests Expired - Fee Related DE69809913T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9715101A GB9715101D0 (en) 1997-07-18 1997-07-18 The production of microstructures for analysis of fluids
PCT/GB1998/002161 WO1999003684A2 (en) 1997-07-18 1998-07-20 The production of microstructures for use in assays

Publications (2)

Publication Number Publication Date
DE69809913D1 DE69809913D1 (de) 2003-01-16
DE69809913T2 true DE69809913T2 (de) 2003-07-10

Family

ID=10816024

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69809913T Expired - Fee Related DE69809913T2 (de) 1997-07-18 1998-07-20 Die herstellung von mikrostrukturen zur verwendung in tests

Country Status (8)

Country Link
US (1) US6440645B1 (de)
EP (1) EP0996547B1 (de)
JP (1) JP2001510276A (de)
AT (1) ATE228939T1 (de)
CA (1) CA2293597A1 (de)
DE (1) DE69809913T2 (de)
GB (1) GB9715101D0 (de)
WO (1) WO1999003684A2 (de)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004005337A1 (de) * 2004-02-04 2005-08-25 Studiengesellschaft Kohle Mbh Mikrofluidische Chips mit immanenten hydrophilen Oberflächen
DE102004013161B4 (de) * 2004-03-17 2008-04-10 microTec Gesellschaft für Mikrotechnologie mbH Mikrofluidik-Chip
DE102008026696A1 (de) * 2008-06-04 2010-06-02 Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. Wirkstoffdepot und ein Dosiersystem für eine kontrollierte Abgabe eines Wirkstoffs

Families Citing this family (110)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US20030040105A1 (en) * 1999-09-30 2003-02-27 Sklar Larry A. Microfluidic micromixer
AU1476601A (en) 1999-11-09 2001-06-06 Sri International Array for the high-throughput synthesis, screening and characterization of combinatorial libraries, and methods for making the array
CA2393603C (en) 1999-12-10 2010-09-21 Massachusetts Institute Of Technology Microchip devices for delivery of molecules and methods of fabrication thereof
ES2420279T3 (es) 2000-03-02 2013-08-23 Microchips, Inc. Dispositivos microfabricados y métodos para almacenamiento y exposición selectiva de productos químicos
AU2001259512B2 (en) * 2000-05-04 2007-03-01 Yale University High density protein arrays for screening of protein activity
SE0001790D0 (sv) * 2000-05-12 2000-05-12 Aamic Ab Hydrophobic barrier
US6777245B2 (en) 2000-06-09 2004-08-17 Advalytix Ag Process for manipulation of small quantities of matter
AU9657901A (en) * 2000-10-03 2002-04-15 Minerva Biotechnologies Corp Magnetic in situ dilution
US7105304B1 (en) * 2000-11-07 2006-09-12 Caliper Life Sciences, Inc. Pressure-based mobility shift assays
US20050221385A1 (en) * 2000-11-07 2005-10-06 Caliper Life Sciences, Inc. Pressure based mobility shift assays
US6864065B2 (en) * 2000-11-08 2005-03-08 Surface Logix, Inc. Assays for monitoring cell motility in real-time
US20020079220A1 (en) * 2000-11-09 2002-06-27 Pawliszyn Janusz B. Micromachining using printing technology
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US20040208751A1 (en) * 2001-05-22 2004-10-21 Lazar Juliana M Microchip integrated multi-channel electroosmotic pumping system
GR1004058B (el) * 2001-05-31 2002-11-15 Φωτοπολυμερικα υλικα με βιοσυμβατες λιθογραφικες απαιτησεις καταλληλα για σχηματοποιηση επιστρωσεων πολλαπλων βioμοριων
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
CA2448902C (en) 2001-06-12 2010-09-07 Pelikan Technologies, Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
CA2448905C (en) 2001-06-12 2010-09-07 Pelikan Technologies, Inc. Blood sampling apparatus and method
AU2002344825A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Method and apparatus for improving success rate of blood yield from a fingerstick
WO2002100254A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
ES2352998T3 (es) 2001-06-12 2011-02-24 Pelikan Technologies Inc. Accionador eléctrico de lanceta.
WO2003012726A1 (en) * 2001-07-27 2003-02-13 Surface Logix, Inc. Method and device for monitoring cell motility in real-time
IE20020619A1 (en) * 2001-12-31 2003-07-23 Provost Fellows And Scholors O An assay assembly
WO2003106693A2 (en) 2002-01-01 2003-12-24 Princeton University Gradient structures interfacing microfluidics and nanofluidics, methods for fabrication and uses thereof
US20030186405A1 (en) * 2002-04-01 2003-10-02 The Ohio State University Research Foundation Micro/nano-embossing process and useful applications thereof
KR100453047B1 (ko) * 2002-04-17 2004-10-15 삼성전자주식회사 잉크 젯 프린트 헤드 및 이의 제조 방법
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US7713214B2 (en) 2002-04-19 2010-05-11 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8372016B2 (en) 2002-04-19 2013-02-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling and analyte sensing
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7534601B2 (en) * 2002-08-27 2009-05-19 Vanderbilt University Capillary perfused bioreactors with multiple chambers
US7790443B2 (en) * 2002-08-27 2010-09-07 Vanderbilt University Bioreactors with substance injection capacity
US7977089B2 (en) * 2002-08-27 2011-07-12 Vanderbilt University Bioreactors with multiple chambers
GB2393246A (en) 2002-09-21 2004-03-24 Sonoptix Ltd Transducer sensor
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
DE10312628A1 (de) * 2003-03-21 2004-10-07 Friz Biochem Gmbh Verfahren und Vorrichtung zum Benetzen eines Substrats mit einer Flüssigkeit
EP2238892A3 (de) 2003-05-30 2011-02-09 Pelikan Technologies Inc. Vorrichtung zur Entnahme von Körperflüssigkeit
US7850621B2 (en) 2003-06-06 2010-12-14 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
JP2005027659A (ja) * 2003-06-20 2005-02-03 Nitto Denko Corp 細胞マイクロチップ
WO2005033659A2 (en) 2003-09-29 2005-04-14 Pelikan Technologies, Inc. Method and apparatus for an improved sample capture device
WO2005037095A1 (en) 2003-10-14 2005-04-28 Pelikan Technologies, Inc. Method and apparatus for a variable user interface
FR2861609B1 (fr) 2003-10-31 2006-02-03 Commissariat Energie Atomique Procede de repartition de gouttes d'un liquide d'interet sur une surface
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
US8668656B2 (en) 2003-12-31 2014-03-11 Sanofi-Aventis Deutschland Gmbh Method and apparatus for improving fluidic flow and sample capture
JP2005234389A (ja) * 2004-02-20 2005-09-02 Fuji Photo Film Co Ltd 科学現象の評価装置、理科実験教材、及びその製造方法
EP1751546A2 (de) 2004-05-20 2007-02-14 Albatros Technologies GmbH & Co. KG Bedruckbares wassergel für biosensoren
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
WO2005120365A1 (en) 2004-06-03 2005-12-22 Pelikan Technologies, Inc. Method and apparatus for a fluid sampling device
JP2006071433A (ja) * 2004-09-01 2006-03-16 Shimadzu Corp 電気泳動方法、電気泳動媒体及び被覆材
CN100488635C (zh) 2004-09-01 2009-05-20 微芯片公司 用于控制释放或者暴露储库内容物的多盖储库装置
WO2006137899A2 (en) * 2004-09-30 2006-12-28 E. I. Du Pont De Nemours And Company Nanosensors for detecting analytes and method of detecting analyteshave been developed in which the redox potential of a redox effector in solution is altered thereby causing changes in the carbon nanotube (30) conductance. the analyte may be detected in solution, eliminating the need for immobilizing the analyte on a support.
WO2006101530A1 (en) * 2004-10-21 2006-09-28 Capecod Biosystems, Inc Thin-film polarization sample cell for biological and chemical agents and a method of sampling
US20080204745A1 (en) * 2004-10-21 2008-08-28 Capecod Biosystems Inc Thin-Film Polarization Sample Cell For Biological And Chemical Agents And A Method Of Sampling
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
US7682816B2 (en) 2005-04-07 2010-03-23 454 Life Sciences Corporation Thin film coated microwell arrays and methods of using same
US7785862B2 (en) * 2005-04-07 2010-08-31 454 Life Sciences Corporation Thin film coated microwell arrays
CN101578520B (zh) * 2006-10-18 2015-09-16 哈佛学院院长等 基于形成图案的多孔介质的横向流动和穿过生物测定装置、及其制备方法和使用方法
US8649840B2 (en) 2007-06-07 2014-02-11 Microchips, Inc. Electrochemical biosensors and arrays
EP2257819A4 (de) 2008-03-27 2017-10-11 President and Fellows of Harvard College Dreidimensionale mikrofluidische vorrichtungen
EP2257818B1 (de) * 2008-03-27 2017-05-10 President and Fellows of Harvard College Baumwollfaden als kostengünstige diagnoseplattform für mehrere assays
US9829488B2 (en) * 2008-03-27 2017-11-28 President And Fellows Of Havard College Paper-based cellular arrays
US8921118B2 (en) 2008-03-27 2014-12-30 President And Fellows Of Harvard College Paper-based microfluidic systems
US9386944B2 (en) 2008-04-11 2016-07-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte detecting device
CA2640787C (en) * 2008-10-08 2015-12-15 Sqi Diagnostics Systems Inc. Array fluorescence equalization method
TW201104253A (en) * 2008-12-31 2011-02-01 Nat Health Research Institutes Microarray chip and method of fabricating for the same
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US9192933B2 (en) 2009-03-06 2015-11-24 President And Fellows Of Harvard College Microfluidic, electrochemical devices
WO2010111265A1 (en) 2009-03-24 2010-09-30 University Of Chicago Slip chip device and methods
US10196700B2 (en) 2009-03-24 2019-02-05 University Of Chicago Multivolume devices, kits and related methods for quantification and detection of nucleic acids and other analytes
US9464319B2 (en) 2009-03-24 2016-10-11 California Institute Of Technology Multivolume devices, kits and related methods for quantification of nucleic acids and other analytes
US9447461B2 (en) 2009-03-24 2016-09-20 California Institute Of Technology Analysis devices, kits, and related methods for digital quantification of nucleic acids and other analytes
WO2011036509A1 (en) * 2009-09-28 2011-03-31 Universitat Rovira I Virgili Screen printed functional microsystems
JP2010008433A (ja) * 2009-10-15 2010-01-14 Enplas Corp 電気泳動装置
AU2011212916B2 (en) 2010-02-03 2015-07-02 President And Fellows Of Harvard College Devices and methods for multiplexed assays
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US20150001084A1 (en) * 2011-12-28 2015-01-01 Agilent Technologies, Inc. Two dimensional nanofluidic ccd arrays for manipulation of charged molecules in solution
US10618050B2 (en) 2015-03-09 2020-04-14 Panasonic Intellectual Property Management Co., Ltd. Microfluidic device for reducing fluctuation in the solution feeding rate of a reaction solution
US20170357656A1 (en) * 2016-06-08 2017-12-14 Hewlett Packard Enterprise Development Lp Reducing file system journaling writes
WO2019193126A1 (en) 2018-04-06 2019-10-10 Fundació Institut De Bioenginyeria De Catalunya (Ibec) Microfluidic structure for carrying out biological assays and chip provided with such structure

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4306013A (en) * 1980-03-10 1981-12-15 Rca Corporation Asymmetrical radiation exposure of spin coated photoresist to obtain uniform thickness coating used to replicate spiral grooves in plastic substrate
JPS58220756A (ja) * 1982-06-18 1983-12-22 Canon Inc インクジエツト記録ヘツドの製造方法
JP2591100B2 (ja) * 1988-09-30 1997-03-19 凸版印刷株式会社 マイクロプレートの製造方法
US5035939A (en) * 1989-08-31 1991-07-30 David Sarnoff Research Center, Inc. Manufacture of printed circuit boards
WO1991003375A1 (en) * 1989-08-31 1991-03-21 David Sarnoff Research Center, Inc. Manufacture of printed circuit boards
US5858188A (en) 1990-02-28 1999-01-12 Aclara Biosciences, Inc. Acrylic microchannels and their use in electrophoretic applications
JP2587124B2 (ja) * 1990-08-09 1997-03-05 株式会社ジーティシー 薄膜トランジスタ回路の製造方法
US5585069A (en) * 1994-11-10 1996-12-17 David Sarnoff Research Center, Inc. Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis
US5856174A (en) * 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
JP2974279B2 (ja) * 1995-07-06 1999-11-10 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー ポリアミド酸を含有するホトレジスト層を有するインクジェットヘッド
DE19545130C2 (de) * 1995-12-04 2001-05-17 Karl Cammann Verfahren und Vorrichtungen für ein modulares Mikrosystem für hochgenaue chemische Schnell-Analysen
US5783452A (en) 1996-02-02 1998-07-21 University Of Washington Covered microchannels and the microfabrication thereof
US5885470A (en) * 1997-04-14 1999-03-23 Caliper Technologies Corporation Controlled fluid transport in microfabricated polymeric substrates

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004005337A1 (de) * 2004-02-04 2005-08-25 Studiengesellschaft Kohle Mbh Mikrofluidische Chips mit immanenten hydrophilen Oberflächen
DE102004013161B4 (de) * 2004-03-17 2008-04-10 microTec Gesellschaft für Mikrotechnologie mbH Mikrofluidik-Chip
DE102008026696A1 (de) * 2008-06-04 2010-06-02 Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. Wirkstoffdepot und ein Dosiersystem für eine kontrollierte Abgabe eines Wirkstoffs

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GB9715101D0 (en) 1997-09-24
ATE228939T1 (de) 2002-12-15
EP0996547A2 (de) 2000-05-03
EP0996547B1 (de) 2002-12-04
DE69809913D1 (de) 2003-01-16
WO1999003684A2 (en) 1999-01-28
CA2293597A1 (en) 1999-01-28
WO1999003684A3 (en) 1999-05-14
WO1999003684A8 (en) 1999-06-17
US6440645B1 (en) 2002-08-27
JP2001510276A (ja) 2001-07-31

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