DE69820268D1 - Implantierbare vorrichtung mit einer polymerbeschichtung zur freisetzung von biologisch wirksamen stoffen - Google Patents
Implantierbare vorrichtung mit einer polymerbeschichtung zur freisetzung von biologisch wirksamen stoffenInfo
- Publication number
- DE69820268D1 DE69820268D1 DE69820268T DE69820268T DE69820268D1 DE 69820268 D1 DE69820268 D1 DE 69820268D1 DE 69820268 T DE69820268 T DE 69820268T DE 69820268 T DE69820268 T DE 69820268T DE 69820268 D1 DE69820268 D1 DE 69820268D1
- Authority
- DE
- Germany
- Prior art keywords
- biologically active
- active substances
- implantable device
- polymer coating
- releasing biologically
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000013543 active substance Substances 0.000 title 1
- 239000011248 coating agent Substances 0.000 title 1
- 238000000576 coating method Methods 0.000 title 1
- 229920000642 polymer Polymers 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
- C25D11/00—Electrolytic coating by surface reaction, i.e. forming conversion layers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D5/00—Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
- C09D5/44—Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes for electrophoretic applications
- C09D5/4476—Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes for electrophoretic applications comprising polymerisation in situ
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/258—Genetic materials, DNA, RNA, genes, vectors, e.g. plasmids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/901—Method of manufacturing prosthetic device
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9709001A FR2766092B1 (fr) | 1997-07-16 | 1997-07-16 | Dispositif implantable recouvert d'un polymere capable de liberer des substances biologiquement actives |
FR9709001 | 1997-07-16 | ||
PCT/FR1998/001538 WO1999003517A1 (fr) | 1997-07-16 | 1998-07-15 | Dispositif implantable recouvert d'un polymere capable de liberer des substances biologiquement actives |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69820268D1 true DE69820268D1 (de) | 2004-01-15 |
DE69820268T2 DE69820268T2 (de) | 2004-10-14 |
Family
ID=9509261
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69820268T Expired - Lifetime DE69820268T2 (de) | 1997-07-16 | 1998-07-15 | Implantierbare vorrichtung mit einer polymerbeschichtung zur freisetzung von biologisch wirksamen stoffen |
Country Status (6)
Country | Link |
---|---|
US (1) | US6468304B1 (de) |
EP (1) | EP1001818B1 (de) |
DE (1) | DE69820268T2 (de) |
ES (1) | ES2212328T3 (de) |
FR (1) | FR2766092B1 (de) |
WO (1) | WO1999003517A1 (de) |
Families Citing this family (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU716005B2 (en) | 1995-06-07 | 2000-02-17 | Cook Medical Technologies Llc | Implantable medical device |
US7713297B2 (en) | 1998-04-11 | 2010-05-11 | Boston Scientific Scimed, Inc. | Drug-releasing stent with ceramic-containing layer |
EP1233795B1 (de) * | 1999-12-03 | 2006-02-15 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Elektropolymerisierbare monomere und polymerbeschichtungen auf implantierbaren geräten |
US20060013850A1 (en) * | 1999-12-03 | 2006-01-19 | Domb Abraham J | Electropolymerizable monomers and polymeric coatings on implantable devices prepared therefrom |
US6899731B2 (en) * | 1999-12-30 | 2005-05-31 | Boston Scientific Scimed, Inc. | Controlled delivery of therapeutic agents by insertable medical devices |
CA2409093C (en) | 2000-05-16 | 2009-07-21 | Regents Of The University Of Minnesota | High mass throughput particle generation using multiple nozzle spraying |
US7727221B2 (en) | 2001-06-27 | 2010-06-01 | Cardiac Pacemakers Inc. | Method and device for electrochemical formation of therapeutic species in vivo |
US6949763B2 (en) * | 2001-10-11 | 2005-09-27 | Marc Ovadia | Semiconductor and non-semiconductor non-diffusion-governed bioelectrodes |
US20030077310A1 (en) | 2001-10-22 | 2003-04-24 | Chandrashekhar Pathak | Stent coatings containing HMG-CoA reductase inhibitors |
GB0125746D0 (en) * | 2001-10-26 | 2001-12-19 | Cathnet Science Holding | Anti-restenosis agent |
US20080215137A1 (en) * | 2003-04-30 | 2008-09-04 | Boston Scientific Scimed, Inc. | Therapeutic driving layer for a medical device |
US20040220656A1 (en) * | 2003-04-30 | 2004-11-04 | Epstein Samuel J. | Coated medical devices and methods of making the same |
US7335185B2 (en) * | 2003-07-18 | 2008-02-26 | Boston Scientific Scimed, Inc. | Protective coatings for medical devices |
US7854756B2 (en) * | 2004-01-22 | 2010-12-21 | Boston Scientific Scimed, Inc. | Medical devices |
WO2006008739A2 (en) * | 2004-07-19 | 2006-01-26 | Elutex Ltd. | Modified conductive surfaces having active substances attached thereto |
US7850645B2 (en) * | 2005-02-11 | 2010-12-14 | Boston Scientific Scimed, Inc. | Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power |
US8005526B2 (en) * | 2005-08-31 | 2011-08-23 | The Regents Of The University Of Michigan | Biologically integrated electrode devices |
US9084546B2 (en) * | 2005-08-31 | 2015-07-21 | The Regents Of The University Of Michigan | Co-electrodeposited hydrogel-conducting polymer electrodes for biomedical applications |
US20070110786A1 (en) * | 2005-11-15 | 2007-05-17 | Boston Scientific Scimed, Inc. | Medical articles having enhanced therapeutic agent binding |
US8840660B2 (en) | 2006-01-05 | 2014-09-23 | Boston Scientific Scimed, Inc. | Bioerodible endoprostheses and methods of making the same |
EP1988941A2 (de) | 2006-01-31 | 2008-11-12 | Nanocopoeia, Inc. | Oberflächenbeschichtung mit nanoteilchen |
CA2637883C (en) | 2006-01-31 | 2015-07-07 | Regents Of The University Of Minnesota | Electrospray coating of objects |
US9108217B2 (en) | 2006-01-31 | 2015-08-18 | Nanocopoeia, Inc. | Nanoparticle coating of surfaces |
US8089029B2 (en) | 2006-02-01 | 2012-01-03 | Boston Scientific Scimed, Inc. | Bioabsorbable metal medical device and method of manufacture |
US20070224235A1 (en) | 2006-03-24 | 2007-09-27 | Barron Tenney | Medical devices having nanoporous coatings for controlled therapeutic agent delivery |
US8187620B2 (en) | 2006-03-27 | 2012-05-29 | Boston Scientific Scimed, Inc. | Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents |
US8048150B2 (en) | 2006-04-12 | 2011-11-01 | Boston Scientific Scimed, Inc. | Endoprosthesis having a fiber meshwork disposed thereon |
EP2035058A2 (de) * | 2006-05-26 | 2009-03-18 | MicroMuscle AB | Vorrichtung und verfahren zur kontrollierten abgabe von chemischen substanzen |
US8815275B2 (en) | 2006-06-28 | 2014-08-26 | Boston Scientific Scimed, Inc. | Coatings for medical devices comprising a therapeutic agent and a metallic material |
CA2655793A1 (en) | 2006-06-29 | 2008-01-03 | Boston Scientific Limited | Medical devices with selective coating |
JP2009545407A (ja) | 2006-08-02 | 2009-12-24 | ボストン サイエンティフィック サイムド,インコーポレイテッド | 三次元分解制御を備えたエンドプロテーゼ |
US8936794B2 (en) * | 2006-08-25 | 2015-01-20 | The Regents Of The University Of Michigan | Conducting polymer nanotube actuators for precisely controlled release of medicine and bioactive molecules |
JP2010503469A (ja) | 2006-09-14 | 2010-02-04 | ボストン サイエンティフィック リミテッド | 薬物溶出性皮膜を有する医療デバイス |
WO2008034066A1 (en) | 2006-09-15 | 2008-03-20 | Boston Scientific Limited | Bioerodible endoprostheses and methods of making the same |
WO2008034013A2 (en) | 2006-09-15 | 2008-03-20 | Boston Scientific Limited | Medical devices and methods of making the same |
JP2010503489A (ja) | 2006-09-15 | 2010-02-04 | ボストン サイエンティフィック リミテッド | 生体内分解性内部人工器官およびその製造方法 |
DE602007011114D1 (de) | 2006-09-15 | 2011-01-20 | Boston Scient Scimed Inc | Biologisch erodierbare endoprothese mit biostabilen anorganischen schichten |
WO2008036548A2 (en) | 2006-09-18 | 2008-03-27 | Boston Scientific Limited | Endoprostheses |
US7981150B2 (en) | 2006-11-09 | 2011-07-19 | Boston Scientific Scimed, Inc. | Endoprosthesis with coatings |
US9040816B2 (en) | 2006-12-08 | 2015-05-26 | Nanocopoeia, Inc. | Methods and apparatus for forming photovoltaic cells using electrospray |
ES2506144T3 (es) | 2006-12-28 | 2014-10-13 | Boston Scientific Limited | Endoprótesis bioerosionables y procedimiento de fabricación de las mismas |
WO2008090555A2 (en) * | 2007-01-22 | 2008-07-31 | Elutex Ltd. | Medical devices having a matrix adhered thereof |
US8070797B2 (en) | 2007-03-01 | 2011-12-06 | Boston Scientific Scimed, Inc. | Medical device with a porous surface for delivery of a therapeutic agent |
US8431149B2 (en) | 2007-03-01 | 2013-04-30 | Boston Scientific Scimed, Inc. | Coated medical devices for abluminal drug delivery |
US8067054B2 (en) | 2007-04-05 | 2011-11-29 | Boston Scientific Scimed, Inc. | Stents with ceramic drug reservoir layer and methods of making and using the same |
WO2008139200A2 (en) * | 2007-05-15 | 2008-11-20 | Chameleon Biosurfaces Limited | Polymer coatings on medical devices |
US7976915B2 (en) | 2007-05-23 | 2011-07-12 | Boston Scientific Scimed, Inc. | Endoprosthesis with select ceramic morphology |
US7942926B2 (en) | 2007-07-11 | 2011-05-17 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
US8002823B2 (en) | 2007-07-11 | 2011-08-23 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
WO2009012353A2 (en) | 2007-07-19 | 2009-01-22 | Boston Scientific Limited | Endoprosthesis having a non-fouling surface |
US7931683B2 (en) | 2007-07-27 | 2011-04-26 | Boston Scientific Scimed, Inc. | Articles having ceramic coated surfaces |
US8815273B2 (en) | 2007-07-27 | 2014-08-26 | Boston Scientific Scimed, Inc. | Drug eluting medical devices having porous layers |
WO2009018340A2 (en) | 2007-07-31 | 2009-02-05 | Boston Scientific Scimed, Inc. | Medical device coating by laser cladding |
JP2010535541A (ja) | 2007-08-03 | 2010-11-25 | ボストン サイエンティフィック リミテッド | 広い表面積を有する医療器具用のコーティング |
US8052745B2 (en) | 2007-09-13 | 2011-11-08 | Boston Scientific Scimed, Inc. | Endoprosthesis |
US7938855B2 (en) | 2007-11-02 | 2011-05-10 | Boston Scientific Scimed, Inc. | Deformable underlayer for stent |
US8216632B2 (en) | 2007-11-02 | 2012-07-10 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
US8029554B2 (en) | 2007-11-02 | 2011-10-04 | Boston Scientific Scimed, Inc. | Stent with embedded material |
WO2009096822A1 (en) | 2008-01-30 | 2009-08-06 | Micromuscle Ab | Drug delivery devices and methods and applications thereof |
EP2271380B1 (de) | 2008-04-22 | 2013-03-20 | Boston Scientific Scimed, Inc. | Medizinprodukte mit einer beschichtung aus anorganischem material |
WO2009132176A2 (en) | 2008-04-24 | 2009-10-29 | Boston Scientific Scimed, Inc. | Medical devices having inorganic particle layers |
US20090292325A1 (en) | 2008-05-02 | 2009-11-26 | Cederna Paul S | Hybrid bioelectrical interface device |
US7998192B2 (en) | 2008-05-09 | 2011-08-16 | Boston Scientific Scimed, Inc. | Endoprostheses |
US8236046B2 (en) | 2008-06-10 | 2012-08-07 | Boston Scientific Scimed, Inc. | Bioerodible endoprosthesis |
EP2303350A2 (de) | 2008-06-18 | 2011-04-06 | Boston Scientific Scimed, Inc. | Endoprothesen-beschichtung |
US7985252B2 (en) | 2008-07-30 | 2011-07-26 | Boston Scientific Scimed, Inc. | Bioerodible endoprosthesis |
US8642063B2 (en) | 2008-08-22 | 2014-02-04 | Cook Medical Technologies Llc | Implantable medical device coatings with biodegradable elastomer and releasable taxane agent |
US8382824B2 (en) | 2008-10-03 | 2013-02-26 | Boston Scientific Scimed, Inc. | Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides |
US20100087783A1 (en) * | 2008-10-07 | 2010-04-08 | Boston Scientific Scimed, Inc. | Medical devices for delivery of therapeutic agents to body lumens |
US8231980B2 (en) | 2008-12-03 | 2012-07-31 | Boston Scientific Scimed, Inc. | Medical implants including iridium oxide |
EP2403546A2 (de) | 2009-03-02 | 2012-01-11 | Boston Scientific Scimed, Inc. | Selbstpufferende medizinische implantate |
US8071156B2 (en) | 2009-03-04 | 2011-12-06 | Boston Scientific Scimed, Inc. | Endoprostheses |
US8287937B2 (en) | 2009-04-24 | 2012-10-16 | Boston Scientific Scimed, Inc. | Endoprosthese |
EP2492351B1 (de) * | 2009-07-30 | 2018-06-06 | Fundacion Cidetec | Elektrochemischer sensor für den nachweis von analyten in flüssigen medien |
US8668732B2 (en) | 2010-03-23 | 2014-03-11 | Boston Scientific Scimed, Inc. | Surface treated bioerodible metal endoprostheses |
US9808616B2 (en) | 2011-01-14 | 2017-11-07 | The Regents Of The University Of Michigan | Regenerative peripheral nerve interface |
US10314725B2 (en) | 2014-11-13 | 2019-06-11 | The Regents Of The University Of Michigan | Method for amplifying signals from individual nerve fascicles |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5599352A (en) * | 1992-03-19 | 1997-02-04 | Medtronic, Inc. | Method of making a drug eluting stent |
EP0566245B1 (de) | 1992-03-19 | 1999-10-06 | Medtronic, Inc. | Intraluminales Erweiterungsgerät |
US5464650A (en) * | 1993-04-26 | 1995-11-07 | Medtronic, Inc. | Intravascular stent and method |
DE4429390A1 (de) | 1994-08-10 | 1996-02-15 | Joachim Dipl Ing Wagenblast | Verfahren zur Aufbereitung und direkten Verarbeitung von verdichtbaren Formteilen und Halbzeugen aus Kunststoffen zu neuen Fertigteilen oder Halbzeugen aus kompakten Kunststoffen oder zu neuen geschäumten Fertigkeiten oder Halbzeugen |
DE4429380C1 (de) * | 1994-08-15 | 1996-04-25 | Biotronik Mess & Therapieg | Verfahren zur Herstellung einer nichtkollabierenden intravasalen Gefäßprothese (Stent) |
FR2724935B1 (fr) | 1994-09-27 | 1996-12-20 | Centre Nat Rech Scient | Compositions nanoparticulaires contenant des derives nucleotidiques, leur preparation et leur emploi en therapeutique |
AU3760595A (en) | 1994-10-04 | 1996-04-26 | Emory University | Methods for regulation of insulin-like growth factor i receptor |
US5609629A (en) * | 1995-06-07 | 1997-03-11 | Med Institute, Inc. | Coated implantable medical device |
US5854223A (en) * | 1995-10-06 | 1998-12-29 | The Trustees Of Columbia University In The City Of New York | S-DC28 as an antirestenosis agent after balloon injury |
US5861032A (en) * | 1996-01-31 | 1999-01-19 | Surface Genesis, Inc. | Medical device having a biocompatible coating and oxidation method of coupling therefor |
-
1997
- 1997-07-16 FR FR9709001A patent/FR2766092B1/fr not_active Expired - Lifetime
-
1998
- 1998-07-15 WO PCT/FR1998/001538 patent/WO1999003517A1/fr active IP Right Grant
- 1998-07-15 EP EP98938748A patent/EP1001818B1/de not_active Expired - Lifetime
- 1998-07-15 US US09/462,881 patent/US6468304B1/en not_active Expired - Lifetime
- 1998-07-15 DE DE69820268T patent/DE69820268T2/de not_active Expired - Lifetime
- 1998-07-15 ES ES98938748T patent/ES2212328T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1001818B1 (de) | 2003-12-03 |
ES2212328T3 (es) | 2004-07-16 |
EP1001818A1 (de) | 2000-05-24 |
FR2766092A1 (fr) | 1999-01-22 |
DE69820268T2 (de) | 2004-10-14 |
US6468304B1 (en) | 2002-10-22 |
FR2766092B1 (fr) | 1999-10-08 |
WO1999003517A1 (fr) | 1999-01-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |