DE69831913D1 - Verfahren, Geräte und Rechnerprogrammeprodukte zum Nachweis der Mengen von Nukleinsäure-Sequenzen in Proben - Google Patents

Verfahren, Geräte und Rechnerprogrammeprodukte zum Nachweis der Mengen von Nukleinsäure-Sequenzen in Proben

Info

Publication number
DE69831913D1
DE69831913D1 DE69831913T DE69831913T DE69831913D1 DE 69831913 D1 DE69831913 D1 DE 69831913D1 DE 69831913 T DE69831913 T DE 69831913T DE 69831913 T DE69831913 T DE 69831913T DE 69831913 D1 DE69831913 D1 DE 69831913D1
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DE
Germany
Prior art keywords
nucleic acid
samples
computer program
amounts
detecting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69831913T
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English (en)
Other versions
DE69831913T2 (de
Inventor
Perry D Haaland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
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Becton Dickinson and Co
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Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of DE69831913D1 publication Critical patent/DE69831913D1/de
Application granted granted Critical
Publication of DE69831913T2 publication Critical patent/DE69831913T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
DE69831913T 1997-05-23 1998-05-22 Verfahren, Geräte und Rechnerprogrammeprodukte zum Nachweis der Mengen von Nukleinsäure-Sequenzen in Proben Expired - Lifetime DE69831913T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US862905 1997-05-23
US08/862,905 US5863736A (en) 1997-05-23 1997-05-23 Method, apparatus and computer program products for determining quantities of nucleic acid sequences in samples

Publications (2)

Publication Number Publication Date
DE69831913D1 true DE69831913D1 (de) 2006-03-02
DE69831913T2 DE69831913T2 (de) 2006-07-13

Family

ID=25339703

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69831913T Expired - Lifetime DE69831913T2 (de) 1997-05-23 1998-05-22 Verfahren, Geräte und Rechnerprogrammeprodukte zum Nachweis der Mengen von Nukleinsäure-Sequenzen in Proben

Country Status (8)

Country Link
US (1) US5863736A (de)
EP (1) EP0915169B1 (de)
JP (1) JP3665477B2 (de)
AT (1) ATE307216T1 (de)
AU (1) AU738398B2 (de)
CA (1) CA2236067C (de)
DE (1) DE69831913T2 (de)
ES (1) ES2251048T3 (de)

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US7090975B2 (en) 1998-03-13 2006-08-15 Promega Corporation Pyrophosphorolysis and incorporation of nucleotide method for nucleic acid detection
US6703211B1 (en) 1998-03-13 2004-03-09 Promega Corporation Cellular detection by providing high energy phosphate donor other than ADP to produce ATP
US6235480B1 (en) * 1998-03-13 2001-05-22 Promega Corporation Detection of nucleic acid hybrids
US6268146B1 (en) 1998-03-13 2001-07-31 Promega Corporation Analytical methods and materials for nucleic acid detection
US6066458A (en) * 1998-05-18 2000-05-23 Becton, Dickinson And Company Methods, apparatus and computer program products for determining quantities of nucleic acid sequences in samples using standard curves and amplification ratio estimates
US6573047B1 (en) 1999-04-13 2003-06-03 Dna Sciences, Inc. Detection of nucleotide sequence variation through fluorescence resonance energy transfer label generation
US6180349B1 (en) 1999-05-18 2001-01-30 The Regents Of The University Of California Quantitative PCR method to enumerate DNA copy number
US6516276B1 (en) * 1999-06-18 2003-02-04 Eos Biotechnology, Inc. Method and apparatus for analysis of data from biomolecular arrays
WO2001013086A2 (en) * 1999-08-13 2001-02-22 Brandeis University Detection of nucleic acids
JP2003517309A (ja) 1999-12-02 2003-05-27 ディーエヌエー サイエンシーズ インコーポレーテッド 単一ヌクレオチドの変異及びジェノタイピングの決定方法
US6783934B1 (en) 2000-05-01 2004-08-31 Cepheid, Inc. Methods for quantitative analysis of nucleic acid amplification reaction
EP1158449A3 (de) * 2000-05-19 2004-12-15 Becton Dickinson and Company Computerverfahren und Vorrichtung zur Analysierung des Lesens von Nukleinsäuretests
US6355433B1 (en) 2000-06-02 2002-03-12 Dna Sciences, Inc. Determination of nucleotide sequence variations through limited primer extension
US7226732B2 (en) * 2001-07-16 2007-06-05 Cepheid Methods, apparatus, and computer programs for verifying the integrity of a probe
US7363168B2 (en) * 2001-10-02 2008-04-22 Stratagene California Adaptive baseline algorithm for quantitative PCR
AU2002351187A1 (en) 2001-11-30 2003-06-17 Fluidigm Corporation Microfluidic device and methods of using same
WO2004003136A2 (en) * 2002-06-28 2004-01-08 Sention, Inc. Methods of detecting sequence differences
NL1021160C2 (nl) * 2002-07-26 2004-01-27 Multigen Internat B V Werkwijze voor het bepalen van het kopieaantal van een nucleotidevolgorde.
US7666361B2 (en) 2003-04-03 2010-02-23 Fluidigm Corporation Microfluidic devices and methods of using same
US7932060B2 (en) * 2003-04-18 2011-04-26 Becton, Dickinson And Company Immuno-amplification
US20050233314A1 (en) * 2003-06-30 2005-10-20 National Health Research Institutes Sensitive and quantitative detection of pathogens by real-time nested PCR
EP1732614B1 (de) * 2004-04-08 2008-12-24 Sangamo Biosciences Inc. Zusammensetzungen zur behandlung von neuropathischen und neurodegenerativen erkrankungen
AU2005233583B2 (en) * 2004-04-08 2011-02-03 Sangamo Therapeutics, Inc. Methods and compositions for modulating cardiac contractility
US20050233332A1 (en) * 2004-04-14 2005-10-20 Collis Matthew P Multiple fluorophore detector system
US20060009916A1 (en) * 2004-07-06 2006-01-12 Xitong Li Quantitative PCR data analysis system (QDAS)
ATE553122T1 (de) * 2005-02-28 2012-04-15 Sangamo Biosciences Inc Antiangiogene methoden und zusammensetzungen
EP2518161A1 (de) 2005-03-18 2012-10-31 Fluidigm Corporation Verfahren zum Nachweis von mutierten Allelen
WO2007019410A2 (en) * 2005-08-05 2007-02-15 The Board Of Trustees Of The Leland Stanford Junior University Mammalian obestatin receptors
WO2007044974A2 (en) * 2005-10-12 2007-04-19 The Research Foundation Of State University Of New York Absolute pcr quantification
DK2623605T3 (en) 2007-04-09 2019-03-25 Univ Florida RAAV VECTOR COMPOSITIONS WITH TYROSIN MODIFIED CAPSIDE PROTEINS AND PROCEDURES FOR USE THEREOF
ATE541946T1 (de) 2007-09-07 2012-02-15 Fluidigm Corp Verfahren und system zur bestimmung von genkopiezahlvarianten
JP2010538612A (ja) * 2007-09-07 2010-12-16 サード ウェーブ テクノロジーズ，インコーポレーテッド 標的の定量化のための方法およびアプリケーション
WO2009098998A1 (ja) * 2008-02-05 2009-08-13 Olympus Corporation 核酸検出方法及び核酸検出用キット
CA2722484A1 (en) * 2008-04-24 2009-10-29 Peter D. Ludowise Analysis of nucleic acid amplification curves using wavelet transformation
WO2011006119A2 (en) 2009-07-09 2011-01-13 The Scripps Research Institute Gene expression profiles associated with chronic allograft nephropathy
CA2805033A1 (en) 2009-07-14 2011-01-20 Beth Israel Deaconess Medical Center, Inc. Methods of increasing liver proliferation
EP2659002B1 (de) 2010-12-27 2017-02-01 Abbott Molecular Inc. Quantifizierung von proben mit hohem titer mittels digitaler pcr
US9222115B2 (en) 2011-12-30 2015-12-29 Abbott Molecular, Inc. Channels with cross-sectional thermal gradients
US9850515B2 (en) 2013-02-08 2017-12-26 Bio-Rad Laboratories, Inc. Affinity-based partition assay for detection of target molecules
EP2994559B1 (de) 2013-05-09 2020-07-08 Bio-rad Laboratories, Inc. Magnetischer immundigitaler pcr-test
WO2015179773A1 (en) 2014-05-22 2015-11-26 The Scripps Research Institute Tissue molecular signatures of kidney transplant rejections
CN105531408B (zh) 2014-02-13 2019-09-10 生物辐射实验室股份有限公司 染色体构象划分产物捕获
US10443100B2 (en) 2014-05-22 2019-10-15 The Scripps Research Institute Gene expression profiles associated with sub-clinical kidney transplant rejection
EP3146076A4 (de) 2014-05-22 2018-05-09 The Scripps Research Institute Mit subklinischer nierentransplantatabstossung assoziierte genexpressionsprofile
US11104951B2 (en) 2014-05-22 2021-08-31 The Scripps Research Institute Molecular signatures for distinguishing liver transplant rejections or injuries
GB2538006A (en) 2014-05-22 2016-11-02 Scripps Research Inst Gene expression profiles associated with sub-clinical kidney transplant rejection
CN107209188A (zh) 2014-06-27 2017-09-26 雅培制药有限公司 用于检测人Pegivirus 2 (HPgV‑2)的组合物和方法
EP3271849B1 (de) 2015-03-17 2021-09-08 Bio-Rad Laboratories, Inc. Nachweis von genomeditierung
US20240003918A1 (en) 2020-11-30 2024-01-04 Enigma Biointelligence, Inc. Non-invasive assessment of alzheimer's disease
CA3217862A1 (en) 2021-05-05 2022-11-10 Radius Pharmaceuticals, Inc. Animal model having homologous recombination of mouse pth1 receptor
WO2023006642A1 (en) 2021-07-26 2023-02-02 Glaxosmithkline Intellectual Property Development Limited Assay methods for titration of retrovirus and retroviral vectors

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US5455166A (en) * 1991-01-31 1995-10-03 Becton, Dickinson And Company Strand displacement amplification
US5994056A (en) * 1991-05-02 1999-11-30 Roche Molecular Systems, Inc. Homogeneous methods for nucleic acid amplification and detection
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US5650277A (en) * 1992-07-02 1997-07-22 Diagenetics Ltd. Method of determining the presence and quantifying the number of di- and trinucleotide repeats
CA2129787A1 (en) * 1993-08-27 1995-02-28 Russell G. Higuchi Monitoring multiple amplification reactions simultaneously and analyzing same
US5547861A (en) * 1994-04-18 1996-08-20 Becton, Dickinson And Company Detection of nucleic acid amplification
DE69519783T2 (de) * 1994-04-29 2001-06-07 Perkin Elmer Corp Verfahren und vorrichtung zur echtzeiterfassung der produkte von nukleinsäureamplifikation
US5766889A (en) * 1994-06-08 1998-06-16 The Perkin-Elmer Corporation Method for determining the characteristics of the concentration growth of target nucleic acid molecules in polymerase chain reaction sample
US5550025A (en) * 1995-07-19 1996-08-27 Becton, Dickinson And Company Detection of hydrophobic amplification products by extraction into an organic phase
US5863736A (en) * 1997-05-23 1999-01-26 Becton, Dickinson And Company Method, apparatus and computer program products for determining quantities of nucleic acid sequences in samples

Also Published As

Publication number Publication date
EP0915169B1 (de) 2005-10-19
JP3665477B2 (ja) 2005-06-29
US5863736A (en) 1999-01-26
CA2236067A1 (en) 1998-11-23
ATE307216T1 (de) 2005-11-15
AU6474998A (en) 1998-11-26
EP0915169A2 (de) 1999-05-12
EP0915169A3 (de) 2002-10-16
ES2251048T3 (es) 2006-04-16
AU738398B2 (en) 2001-09-20
CA2236067C (en) 2003-08-05
DE69831913T2 (de) 2006-07-13
JPH114688A (ja) 1999-01-12

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