DE69831913D1 - Verfahren, Geräte und Rechnerprogrammeprodukte zum Nachweis der Mengen von Nukleinsäure-Sequenzen in Proben - Google Patents

Verfahren, Geräte und Rechnerprogrammeprodukte zum Nachweis der Mengen von Nukleinsäure-Sequenzen in Proben

Info

Publication number
DE69831913D1
DE69831913D1 DE69831913T DE69831913T DE69831913D1 DE 69831913 D1 DE69831913 D1 DE 69831913D1 DE 69831913 T DE69831913 T DE 69831913T DE 69831913 T DE69831913 T DE 69831913T DE 69831913 D1 DE69831913 D1 DE 69831913D1
Authority
DE
Germany
Prior art keywords
nucleic acid
samples
computer program
amounts
detecting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69831913T
Other languages
English (en)
Other versions
DE69831913T2 (de
Inventor
Perry D Haaland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of DE69831913D1 publication Critical patent/DE69831913D1/de
Application granted granted Critical
Publication of DE69831913T2 publication Critical patent/DE69831913T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6851Quantitative amplification
DE69831913T 1997-05-23 1998-05-22 Verfahren, Geräte und Rechnerprogrammeprodukte zum Nachweis der Mengen von Nukleinsäure-Sequenzen in Proben Expired - Lifetime DE69831913T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/862,905 US5863736A (en) 1997-05-23 1997-05-23 Method, apparatus and computer program products for determining quantities of nucleic acid sequences in samples
US862905 1997-05-23

Publications (2)

Publication Number Publication Date
DE69831913D1 true DE69831913D1 (de) 2006-03-02
DE69831913T2 DE69831913T2 (de) 2006-07-13

Family

ID=25339703

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69831913T Expired - Lifetime DE69831913T2 (de) 1997-05-23 1998-05-22 Verfahren, Geräte und Rechnerprogrammeprodukte zum Nachweis der Mengen von Nukleinsäure-Sequenzen in Proben

Country Status (8)

Country Link
US (1) US5863736A (de)
EP (1) EP0915169B1 (de)
JP (1) JP3665477B2 (de)
AT (1) ATE307216T1 (de)
AU (1) AU738398B2 (de)
CA (1) CA2236067C (de)
DE (1) DE69831913T2 (de)
ES (1) ES2251048T3 (de)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5863736A (en) * 1997-05-23 1999-01-26 Becton, Dickinson And Company Method, apparatus and computer program products for determining quantities of nucleic acid sequences in samples
US7090975B2 (en) 1998-03-13 2006-08-15 Promega Corporation Pyrophosphorolysis and incorporation of nucleotide method for nucleic acid detection
US6270973B1 (en) 1998-03-13 2001-08-07 Promega Corporation Multiplex method for nucleic acid detection
US6391551B1 (en) 1998-03-13 2002-05-21 Promega Corporation Detection of nucleic acid hybrids
US6312902B1 (en) 1998-03-13 2001-11-06 Promega Corporation Nucleic acid detection
US6277578B1 (en) 1998-03-13 2001-08-21 Promega Corporation Deploymerization method for nucleic acid detection of an amplified nucleic acid target
US6270974B1 (en) 1998-03-13 2001-08-07 Promega Corporation Exogenous nucleic acid detection
US6235480B1 (en) * 1998-03-13 2001-05-22 Promega Corporation Detection of nucleic acid hybrids
US6268146B1 (en) 1998-03-13 2001-07-31 Promega Corporation Analytical methods and materials for nucleic acid detection
US6703211B1 (en) 1998-03-13 2004-03-09 Promega Corporation Cellular detection by providing high energy phosphate donor other than ADP to produce ATP
US6066458A (en) * 1998-05-18 2000-05-23 Becton, Dickinson And Company Methods, apparatus and computer program products for determining quantities of nucleic acid sequences in samples using standard curves and amplification ratio estimates
US6573047B1 (en) 1999-04-13 2003-06-03 Dna Sciences, Inc. Detection of nucleotide sequence variation through fluorescence resonance energy transfer label generation
US6180349B1 (en) 1999-05-18 2001-01-30 The Regents Of The University Of California Quantitative PCR method to enumerate DNA copy number
US6516276B1 (en) * 1999-06-18 2003-02-04 Eos Biotechnology, Inc. Method and apparatus for analysis of data from biomolecular arrays
WO2001013086A2 (en) * 1999-08-13 2001-02-22 Brandeis University Detection of nucleic acids
US6458544B1 (en) 1999-12-02 2002-10-01 Dna Sciences, Inc. Methods for determining single nucleotide variations and genotyping
US6783934B1 (en) 2000-05-01 2004-08-31 Cepheid, Inc. Methods for quantitative analysis of nucleic acid amplification reaction
EP1158449A3 (de) * 2000-05-19 2004-12-15 Becton Dickinson and Company Computerverfahren und Vorrichtung zur Analysierung des Lesens von Nukleinsäuretests
US6355433B1 (en) 2000-06-02 2002-03-12 Dna Sciences, Inc. Determination of nucleotide sequence variations through limited primer extension
US7226732B2 (en) * 2001-07-16 2007-06-05 Cepheid Methods, apparatus, and computer programs for verifying the integrity of a probe
US7363168B2 (en) * 2001-10-02 2008-04-22 Stratagene California Adaptive baseline algorithm for quantitative PCR
EP1463796B1 (de) 2001-11-30 2013-01-09 Fluidigm Corporation Mikrofluidische vorrichtung und verfahren zu ihrer verwendung
KR101038137B1 (ko) * 2002-06-28 2011-05-31 프리메라디엑스, 인크. 서열 차이를 감지하는 방법
NL1021160C2 (nl) * 2002-07-26 2004-01-27 Multigen Internat B V Werkwijze voor het bepalen van het kopieaantal van een nucleotidevolgorde.
US7666361B2 (en) 2003-04-03 2010-02-23 Fluidigm Corporation Microfluidic devices and methods of using same
CN101410530B (zh) 2003-04-18 2013-03-27 贝克顿·迪金森公司 免疫-扩增
US20050233314A1 (en) * 2003-06-30 2005-10-20 National Health Research Institutes Sensitive and quantitative detection of pathogens by real-time nested PCR
CA2561714A1 (en) * 2004-04-08 2005-10-27 Sangamo Biosciences, Inc. Methods and compositions for treating neuropathic and neurodegenerative conditions
CA2561565C (en) * 2004-04-08 2013-11-26 Sangamo Biosciences, Inc. Methods for repression of phospholamban gene and modulating cardiac contractility
US20050233332A1 (en) * 2004-04-14 2005-10-20 Collis Matthew P Multiple fluorophore detector system
US20060009916A1 (en) * 2004-07-06 2006-01-12 Xitong Li Quantitative PCR data analysis system (QDAS)
EP2314614B1 (de) 2005-02-28 2015-11-25 Sangamo BioSciences, Inc. Anti-angiogene Verfahren und Zusammensetzungen
EP2518161A1 (de) 2005-03-18 2012-10-31 Fluidigm Corporation Verfahren zum Nachweis von mutierten Allelen
WO2007019410A2 (en) * 2005-08-05 2007-02-15 The Board Of Trustees Of The Leland Stanford Junior University Mammalian obestatin receptors
US8831887B2 (en) * 2005-10-12 2014-09-09 The Research Foundation For The State University Of New York Absolute PCR quantification
EP2191001B1 (de) 2007-04-09 2016-06-08 University of Florida Research Foundation, Inc. Raav-vektorzusammensetzungen mit tyrosin-modifizierten capsidproteinen und verwendungsverfahren
BRPI0816393A2 (pt) 2007-09-07 2015-03-03 Fluidigm Corp Método para determinar o número de cópias relativo de uma sequência de polinucleotídeo alvo em um genoma de um indivíduo
WO2009033156A2 (en) * 2007-09-07 2009-03-12 Third Wave Technologies, Inc. Methods and applications for target quantification
US8530165B2 (en) * 2008-02-05 2013-09-10 Olympus Corporation Nucleic acid detection method for determining if one or more analyte nucleotides are present in a nucleic acid
KR20110008261A (ko) * 2008-04-24 2011-01-26 쓰리엠 이노베이티브 프로퍼티즈 컴파니 웨이블릿 변환을 사용한 핵산 증폭 곡선의 분석
CA2767616A1 (en) 2009-07-09 2011-01-13 The Scripps Research Institute Gene expression profiles associated with chronic allograft nephropathy
EP2453882A1 (de) 2009-07-14 2012-05-23 Beth Israel Deaconess Medical Center, Inc. Verfahren zur erhöhung der leberproliferation
EP3181704B1 (de) 2010-12-27 2021-01-27 Abbott Molecular Inc. Quantifizierung von proben mit hohem titer mittels digitaler pcr
CA2863121A1 (en) 2011-12-30 2013-07-04 Abbott Molecular Inc. Microorganism nucleic acid purification from host samples
WO2014124046A1 (en) 2013-02-08 2014-08-14 Bio-Rad Laboratories, Inc. Affinity-based partition assay for detection of target molecules
US9896717B2 (en) 2013-05-09 2018-02-20 Bio-Rad Laboratories, Inc. Magnetic immuno digital PCR assay
EP2986761B1 (de) 2014-02-13 2018-08-15 Bio-rad Laboratories, Inc. Chromosomenkonformationserfassung in tröpfchen partitionen
CA2949959A1 (en) 2014-05-22 2015-11-26 Northwestern University Gene expression profiles associated with sub-clinical kidney transplant rejection
US10443100B2 (en) 2014-05-22 2019-10-15 The Scripps Research Institute Gene expression profiles associated with sub-clinical kidney transplant rejection
US11104951B2 (en) 2014-05-22 2021-08-31 The Scripps Research Institute Molecular signatures for distinguishing liver transplant rejections or injuries
EP3146076A4 (de) 2014-05-22 2018-05-09 The Scripps Research Institute Mit subklinischer nierentransplantatabstossung assoziierte genexpressionsprofile
EP3146077A4 (de) 2014-05-22 2018-05-02 The Scripps Research Institute Molekulare gewebesignaturen von nierentransplantatabstossungen
BR112016030008A2 (pt) 2014-06-27 2017-10-24 Abbott Lab método para a detecção de infecção por pegivirus humano 2 em um indivíduo, para a detecção de ácido nucleico de pegivirus humano 2 e para a detecção de pegivirus humano 2 em uma amostra, e, composição
EP3271849B1 (de) 2015-03-17 2021-09-08 Bio-Rad Laboratories, Inc. Nachweis von genomeditierung
WO2022115705A2 (en) 2020-11-30 2022-06-02 Enigma Biointelligence, Inc. Non-invasive assessment of alzheimer's disease
CA3217862A1 (en) 2021-05-05 2022-11-10 Radius Pharmaceuticals, Inc. Animal model having homologous recombination of mouse pth1 receptor
WO2023006642A1 (en) 2021-07-26 2023-02-02 Glaxosmithkline Intellectual Property Development Limited Assay methods for titration of retrovirus and retroviral vectors

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5219727A (en) * 1989-08-21 1993-06-15 Hoffmann-Laroche Inc. Quantitation of nucleic acids using the polymerase chain reaction
US5455166A (en) * 1991-01-31 1995-10-03 Becton, Dickinson And Company Strand displacement amplification
US5994056A (en) * 1991-05-02 1999-11-30 Roche Molecular Systems, Inc. Homogeneous methods for nucleic acid amplification and detection
US5270184A (en) * 1991-11-19 1993-12-14 Becton, Dickinson And Company Nucleic acid target generation
US5650277A (en) * 1992-07-02 1997-07-22 Diagenetics Ltd. Method of determining the presence and quantifying the number of di- and trinucleotide repeats
CA2129787A1 (en) * 1993-08-27 1995-02-28 Russell G. Higuchi Monitoring multiple amplification reactions simultaneously and analyzing same
US5547861A (en) * 1994-04-18 1996-08-20 Becton, Dickinson And Company Detection of nucleic acid amplification
JP2909216B2 (ja) * 1994-04-29 1999-06-23 パーキン‐エルマー コーポレイション 核酸増幅生成物のリアルタイム検出装置
US5766889A (en) * 1994-06-08 1998-06-16 The Perkin-Elmer Corporation Method for determining the characteristics of the concentration growth of target nucleic acid molecules in polymerase chain reaction sample
US5550025A (en) * 1995-07-19 1996-08-27 Becton, Dickinson And Company Detection of hydrophobic amplification products by extraction into an organic phase
US5863736A (en) * 1997-05-23 1999-01-26 Becton, Dickinson And Company Method, apparatus and computer program products for determining quantities of nucleic acid sequences in samples

Also Published As

Publication number Publication date
AU738398B2 (en) 2001-09-20
JP3665477B2 (ja) 2005-06-29
ES2251048T3 (es) 2006-04-16
ATE307216T1 (de) 2005-11-15
EP0915169A3 (de) 2002-10-16
JPH114688A (ja) 1999-01-12
US5863736A (en) 1999-01-26
CA2236067A1 (en) 1998-11-23
CA2236067C (en) 2003-08-05
EP0915169A2 (de) 1999-05-12
EP0915169B1 (de) 2005-10-19
AU6474998A (en) 1998-11-26
DE69831913T2 (de) 2006-07-13

Similar Documents

Publication Publication Date Title
DE69831913D1 (de) Verfahren, Geräte und Rechnerprogrammeprodukte zum Nachweis der Mengen von Nukleinsäure-Sequenzen in Proben
WO2001084463A3 (en) Apparatus, method, and computer program product for quantitative analysis of a nucleic acid amplification reaction
ATE65842T1 (de) Vorrichtung und verfahren zum pruefen der gleichfoermigkeit von rotationskoerpern.
EP1541998A4 (de) Probenanalyseverfahren und probenanalyseeinrichtung
ATE295541T1 (de) Verfahren und vorrichtung zur untersuchung von wirksstoffskandidaten und zur bestimmung ihrer pharmakokinetischen parametern
DK0901634T3 (da) System til bestemmelse af mindst en parameter i mindst en prøve af en fysiologisk væske samt en kassette
DE69618460T2 (de) Verfahren zum nachweis von nukleinsäuresequenzen unter verwendung von kompetitiven amplifikation
DK1639130T3 (da) Prober, biblioteker og kits til analyse af blandinger af nukleinsyrer og metoder til opbygning af disse
KR850002317A (ko) 고무의 경화 및 시험방법
ATE541048T1 (de) Verfahren und vorrichtung zum nachweisen und/oder bestimmen der in einer probe enthaltenen bakterien
ATE384139T1 (de) Multi-test-analyse von echzeit- nukleinsäureamplifikationen
ATE280838T1 (de) Verfahren zur identifikation von nucleinsäuren durch elektrospray massenspektrometrie
DE60112949D1 (de) Verfahren zum nachweis eines lipoprotein-akutphaseprotein-komplexes
ATE412775T1 (de) Verfahren zur quantifizierung von nukleinsäuren mittels bestimmung der zellzahl
DE69529691D1 (de) Differenziertes timingsverfahren zum nachweiss multiple analyte in eine testprobe
ATE327347T1 (de) Verfahren für die gleichzeitige und mehrfache detektion und quantifizierung der hybridisierung von molekülverbindungen wie nukleinsäuren, dns, rns, pns und proteinen
Curry The detection and measurement of crack growth during ductile fracture
ATE386141T1 (de) Zusammensetzungen und verfahren für den nachweis von polynukleotiden
MY129433A (en) Enzyme detection and measurement
ATE317454T1 (de) Verfahren zur aktivitätsbestimmung einer substanz mittels eines funktionellen in vitro tests
NO922515D0 (no) Fremgangsmaate til aa bestemme hvorvidt et klinisk proevemateriale er egnet til bruk i nukleinsyrehybridiseringsforsoekog testkit for utfoerelse av fremgangsmaaten
ATE347108T1 (de) Zusammensetzungen und verfahren zum bestimmen von aa4rp
ATE295114T1 (de) Gerät und verfahren zur messung von biologischen strukturen
US20060205082A1 (en) Reaction rate determination
ATE184109T1 (de) Indikatorreagenzien zum nachweis oder zur messung von analyten, testsatz, der diese enthält, und verfahren zum nachweis oder zur messung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition