DE69841279D1 - Verwendung von humanem Parathyroid-hormon - Google Patents
Verwendung von humanem Parathyroid-hormonInfo
- Publication number
- DE69841279D1 DE69841279D1 DE69841279T DE69841279T DE69841279D1 DE 69841279 D1 DE69841279 D1 DE 69841279D1 DE 69841279 T DE69841279 T DE 69841279T DE 69841279 T DE69841279 T DE 69841279T DE 69841279 D1 DE69841279 D1 DE 69841279D1
- Authority
- DE
- Germany
- Prior art keywords
- parathyroid hormone
- human parathyroid
- human
- osteoporosis
- medicament
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/29—Parathyroid hormone (parathormone); Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/452—Piperidinium derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9702401A SE9702401D0 (sv) | 1997-06-19 | 1997-06-19 | Pharmaceutical use |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69841279D1 true DE69841279D1 (de) | 2009-12-17 |
Family
ID=20407482
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69841279T Expired - Lifetime DE69841279D1 (de) | 1997-06-19 | 1998-06-08 | Verwendung von humanem Parathyroid-hormon |
DE69826132T Expired - Lifetime DE69826132T2 (de) | 1997-06-19 | 1998-06-08 | Pharmazeutisches kombinationspräparat aus parathormon und einem inhibitor der knochenresorption |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69826132T Expired - Lifetime DE69826132T2 (de) | 1997-06-19 | 1998-06-08 | Pharmazeutisches kombinationspräparat aus parathormon und einem inhibitor der knochenresorption |
Country Status (15)
Country | Link |
---|---|
US (8) | US6284730B1 (de) |
EP (2) | EP1001802B1 (de) |
JP (3) | JP4989811B2 (de) |
AT (2) | ATE447410T1 (de) |
AU (1) | AU753477B2 (de) |
CA (2) | CA2698626C (de) |
CY (1) | CY1110287T1 (de) |
DE (2) | DE69841279D1 (de) |
DK (2) | DK1473040T3 (de) |
ES (2) | ES2335404T3 (de) |
HK (2) | HK1029738A1 (de) |
PT (2) | PT1473040E (de) |
SE (1) | SE9702401D0 (de) |
WO (1) | WO1998057656A1 (de) |
ZA (1) | ZA984947B (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9702401D0 (sv) * | 1997-06-19 | 1997-06-19 | Astra Ab | Pharmaceutical use |
HU228400B1 (en) | 2000-06-20 | 2013-03-28 | Novartis Ag | The use of bisphosphonates for treatment of osteoporosis |
CA2372450A1 (en) * | 2001-05-10 | 2001-09-19 | Pharmaceutical Partners Of Canada Inc. | Liquid injectable formulation of disodium pamidronate |
CN101837120A (zh) | 2001-06-01 | 2010-09-22 | 诺瓦提斯公司 | 口服施用甲状旁腺激素和降钙素 |
EP1399135B1 (de) * | 2001-06-28 | 2004-12-29 | Microchips, Inc. | Verfahren zum hermetischen versiegeln von mikrochip-reservoir-vorrichtungen |
TWI329105B (en) | 2002-02-01 | 2010-08-21 | Rigel Pharmaceuticals Inc | 2,4-pyrimidinediamine compounds and their uses |
WO2004022033A1 (en) * | 2002-09-04 | 2004-03-18 | Microchips, Inc. | Method and device for the controlled delivery of parathyroid hormone |
NZ545270A (en) | 2003-07-30 | 2010-04-30 | Rigel Pharmaceuticals Inc | 2,4-Pyrimidinediamine compounds for use in the treatment or prevention of autoimmune diseases |
US20050119183A1 (en) * | 2003-11-12 | 2005-06-02 | Nps Allelix Corp. | Method for treating bone loss using parathyroid hormone |
WO2006081279A2 (en) | 2005-01-25 | 2006-08-03 | Microchips, Inc. | Control of drug release by transient modification of local microenvironments |
WO2006135915A2 (en) | 2005-06-13 | 2006-12-21 | Rigel Pharmaceuticals, Inc. | Methods and compositions for treating degenerative bone disorders |
PL1734251T3 (pl) * | 2005-06-17 | 2007-05-31 | Magneti Marelli Powertrain Spa | Wtryskiwacz paliwa |
CN101355959B (zh) * | 2005-11-10 | 2013-02-27 | 密歇根理工大学管理委员会 | 黑熊甲状旁腺素和使用黑熊甲状旁腺素的方法 |
WO2010115932A1 (en) * | 2009-04-08 | 2010-10-14 | Novartis Ag | Combination for the treatment of bone loss |
CN103893746A (zh) * | 2009-09-09 | 2014-07-02 | 旭化成制药株式会社 | 含有pth的骨质疏松症治疗/预防剂 |
BR112012013725A2 (pt) | 2009-12-07 | 2017-01-10 | Univ Michigan Tech | paratormônio de urso preto e métodos de usar o paratormônio de uso preto. |
AU2012354056B2 (en) * | 2011-12-13 | 2017-10-05 | Amorphical Ltd. | Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders |
CN107921060A (zh) | 2015-06-04 | 2018-04-17 | 艾玛菲克有限公司 | 用于吸入施用、舌下施用或含服施用的无定形碳酸钙的组合物 |
JP7152785B2 (ja) | 2016-10-25 | 2022-10-13 | アモーフィカル リミテッド. | 白血病治療のための非晶質炭酸カルシウム |
Family Cites Families (67)
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US3768177A (en) | 1972-08-02 | 1973-10-30 | R Thomas | Educational device |
US3886132A (en) | 1972-12-21 | 1975-05-27 | Us Health | Human parathyroid hormone |
US4237224A (en) | 1974-11-04 | 1980-12-02 | Board Of Trustees Of The Leland Stanford Jr. University | Process for producing biologically functional molecular chimeras |
US4468464A (en) | 1974-11-04 | 1984-08-28 | The Board Of Trustees Of The Leland Stanford Junior University | Biologically functional molecular chimeras |
US4105602A (en) | 1975-02-10 | 1978-08-08 | Armour Pharmaceutical Company | Synthesis of peptides with parathyroid hormone activity |
US4016314A (en) | 1975-06-26 | 1977-04-05 | Hallco Inc. | Embroidered fruit bowl wall hanging and kit for making same |
US4264731A (en) | 1977-05-27 | 1981-04-28 | The Regents Of The University Of California | DNA Joining method |
US4366246A (en) | 1977-11-08 | 1982-12-28 | Genentech, Inc. | Method for microbial polypeptide expression |
US4199060A (en) | 1978-07-20 | 1980-04-22 | Howard Hardware Products, Inc. | Lock installation kit |
US4425437A (en) | 1979-11-05 | 1984-01-10 | Genentech, Inc. | Microbial polypeptide expression vehicle |
US4338397A (en) | 1980-04-11 | 1982-07-06 | President And Fellows Of Harvard College | Mature protein synthesis |
US4383066A (en) | 1980-04-15 | 1983-05-10 | Mitsubishi Gas Chemical Company, Inc. | Polyphenylene ether resin composition |
JPS5825439B2 (ja) | 1980-12-30 | 1983-05-27 | 株式会社林原生物化学研究所 | ヒト副甲状腺ホルモンの製造方法 |
US4394443A (en) | 1980-12-18 | 1983-07-19 | Yale University | Method for cloning genes |
US4624926A (en) | 1981-01-02 | 1986-11-25 | The Research Foundation Of State University Of New York | Novel cloning vehicles for polypeptide expression in microbial hosts |
NO163060C (no) | 1981-03-13 | 1990-03-28 | Damon Biotech Inc | Fremgangsmaate for fremstilling av substanser som dannes av levende celler som produserer interferoner eller antistoffer. |
US4385212A (en) | 1981-10-05 | 1983-05-24 | Bell Telephone Laboratories Incorporated | Expandable communication terminal housing |
US4424278A (en) | 1981-11-16 | 1984-01-03 | Research Corporation | Cancer detection procedure using an acyl carrier protein |
US4532207A (en) | 1982-03-19 | 1985-07-30 | G. D. Searle & Co. | Process for the preparation of polypeptides utilizing a charged amino acid polymer and exopeptidase |
US4546082A (en) | 1982-06-17 | 1985-10-08 | Regents Of The Univ. Of California | E. coli/Saccharomyces cerevisiae plasmid cloning vector containing the alpha-factor gene for secretion and processing of hybrid proteins |
US4595658A (en) | 1982-09-13 | 1986-06-17 | The Rockefeller University | Method for facilitating externalization of proteins synthesized in bacteria |
WO1984001173A1 (en) | 1982-09-15 | 1984-03-29 | Immuno Nuclear Corp | Production of mature proteins in transformed yeast |
DE3312928A1 (de) | 1983-04-11 | 1984-11-22 | Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig | Human-parathormon produzierende hybridvektoren und human-parathormongen |
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US4637980A (en) | 1983-08-09 | 1987-01-20 | Smithkline Beckman Corporation | Externalization of products of bacteria |
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EP0177343B1 (de) | 1984-10-05 | 1992-07-22 | Genentech, Inc. | DNA, Zellkulturen und Verfahren zur Sekretion von heterologen Proteinen und periplasmische Proteinrückgewinnung |
JPS61267528A (ja) | 1984-11-26 | 1986-11-27 | Yamanouchi Pharmaceut Co Ltd | 吸収促進剤を含有するカルシトニン経鼻剤 |
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IL78342A (en) | 1985-04-04 | 1991-06-10 | Gen Hospital Corp | Pharmaceutical composition for treatment of osteoporosis in humans comprising a parathyroid hormone or a fragment thereof |
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US5223407A (en) | 1988-08-31 | 1993-06-29 | Allelix Inc. | Excretion of heterologous proteins from e. coli |
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US5171670A (en) | 1989-05-12 | 1992-12-15 | The General Hospital Corporation | Recombinant dna method for production of parathyroid hormone |
USRE37919E1 (en) | 1989-05-12 | 2002-12-03 | The General Hospital Corporation | Recombinant DNA method for production of parathyroid hormone |
US5744444A (en) * | 1989-10-27 | 1998-04-28 | Haemopep Pharma Gmbh | HPTH-fragment-(1-37), the preparation thereof, medicaments containing same and the use thereof |
DE3935738A1 (de) | 1989-10-27 | 1991-05-08 | Forssmann Wolf Georg | Arzneimittel, enthaltend das humane parathormon-fragment (1-37) als aktiven wirkstoff |
GB9020544D0 (en) | 1990-09-20 | 1990-10-31 | Sandoz Ltd | Improvements in or relating to organic compounds |
EP0559751B1 (de) | 1990-11-26 | 1997-03-26 | RECKER, Robert R. | Behandlung von osteoporose unter verwendung von wachstumshormon-freisetzendem faktor (grf) in verbindung mit parathyroidhormon (pth) |
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IT1255723B (it) | 1992-10-09 | 1995-11-13 | Uso di paratormone,suoi frammenti biologicamente attivi e peptidi correlati, per la preparazione di composizioni farmaceutiche utili nella prevenzione e terapia dell'aborto e del parto pretermine ed in generale per il trattamento della gestazione | |
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WO1996007416A1 (en) | 1994-09-09 | 1996-03-14 | The Procter & Gamble Company | Estrogens and parathyroid hormone for treating osteoporosis |
AU686458B2 (en) * | 1994-09-09 | 1998-02-05 | Procter & Gamble Company, The | Methods for the treatment of osteoporosis using bone active phosphonates and parathyroid hormone |
US5747456A (en) * | 1994-12-19 | 1998-05-05 | Beth Israel Deaconess Medical Center | Continuous low-dose administration of parathyroid hormone or its agonist |
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IL120270A0 (en) * | 1996-02-28 | 1997-06-10 | Pfizer | Combination therapy to treat osteoporosis |
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SE9702401D0 (sv) * | 1997-06-19 | 1997-06-19 | Astra Ab | Pharmaceutical use |
-
1997
- 1997-06-19 SE SE9702401A patent/SE9702401D0/xx unknown
-
1998
- 1998-06-08 WO PCT/SE1998/001095 patent/WO1998057656A1/en active IP Right Grant
- 1998-06-08 CA CA2698626A patent/CA2698626C/en not_active Expired - Fee Related
- 1998-06-08 PT PT04017622T patent/PT1473040E/pt unknown
- 1998-06-08 ZA ZA984947A patent/ZA984947B/xx unknown
- 1998-06-08 PT PT98929965T patent/PT1001802E/pt unknown
- 1998-06-08 CA CA2294101A patent/CA2294101C/en not_active Expired - Fee Related
- 1998-06-08 AT AT04017622T patent/ATE447410T1/de active
- 1998-06-08 DE DE69841279T patent/DE69841279D1/de not_active Expired - Lifetime
- 1998-06-08 EP EP98929965A patent/EP1001802B1/de not_active Expired - Lifetime
- 1998-06-08 AT AT98929965T patent/ATE275419T1/de active
- 1998-06-08 JP JP50425999A patent/JP4989811B2/ja not_active Expired - Fee Related
- 1998-06-08 DK DK04017622.4T patent/DK1473040T3/da active
- 1998-06-08 US US09/125,247 patent/US6284730B1/en not_active Expired - Lifetime
- 1998-06-08 EP EP04017622A patent/EP1473040B1/de not_active Expired - Lifetime
- 1998-06-08 DK DK98929965T patent/DK1001802T3/da active
- 1998-06-08 ES ES04017622T patent/ES2335404T3/es not_active Expired - Lifetime
- 1998-06-08 DE DE69826132T patent/DE69826132T2/de not_active Expired - Lifetime
- 1998-06-08 ES ES98929965T patent/ES2229511T3/es not_active Expired - Lifetime
- 1998-06-08 AU AU79458/98A patent/AU753477B2/en not_active Ceased
-
2000
- 2000-11-23 HK HK00107524A patent/HK1029738A1/xx not_active IP Right Cessation
-
2001
- 2001-08-31 US US09/942,661 patent/US20020002135A1/en not_active Abandoned
-
2003
- 2003-03-18 US US10/389,797 patent/US7018982B2/en not_active Expired - Fee Related
-
2005
- 2005-04-22 HK HK05103473.5A patent/HK1070816A1/xx not_active IP Right Cessation
- 2005-12-19 US US11/305,339 patent/US7507715B2/en not_active Expired - Fee Related
-
2009
- 2009-01-09 US US12/351,558 patent/US7749543B2/en not_active Expired - Fee Related
-
2010
- 2010-01-04 JP JP2010000066A patent/JP5525825B2/ja not_active Expired - Fee Related
- 2010-01-29 CY CY20101100091T patent/CY1110287T1/el unknown
- 2010-06-23 US US12/822,089 patent/US8153588B2/en not_active Expired - Fee Related
-
2012
- 2012-02-24 US US13/405,093 patent/US8765674B2/en not_active Expired - Fee Related
-
2013
- 2013-10-02 JP JP2013206919A patent/JP2014015479A/ja active Pending
-
2014
- 2014-05-22 US US14/285,437 patent/US20140256632A1/en not_active Abandoned
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