DE69841888D1 - Gerät zur verabreichung von medikamenten und genen mittels elektroporation - Google Patents

Gerät zur verabreichung von medikamenten und genen mittels elektroporation

Info

Publication number
DE69841888D1
DE69841888D1 DE69841888T DE69841888T DE69841888D1 DE 69841888 D1 DE69841888 D1 DE 69841888D1 DE 69841888 T DE69841888 T DE 69841888T DE 69841888 T DE69841888 T DE 69841888T DE 69841888 D1 DE69841888 D1 DE 69841888D1
Authority
DE
Germany
Prior art keywords
electroporation
ept
therapy
vivo
tumors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69841888T
Other languages
English (en)
Inventor
Gunter A Hofmann
Sukhendu B Dev
Steven C Dimmer
Jeffrey I Levatter
Gurvinder S Nanda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetronics Inc
Original Assignee
Genetronics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetronics Inc filed Critical Genetronics Inc
Application granted granted Critical
Publication of DE69841888D1 publication Critical patent/DE69841888D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0502Skin piercing electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Cardiology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69841888T 1997-08-01 1998-07-31 Gerät zur verabreichung von medikamenten und genen mittels elektroporation Expired - Lifetime DE69841888D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/905,240 US6055453A (en) 1997-08-01 1997-08-01 Apparatus for addressing needle array electrodes for electroporation therapy
PCT/US1998/016042 WO1999006101A1 (en) 1997-08-01 1998-07-31 Method and apparatus for using electroporation mediated delivery of drugs and genes

Publications (1)

Publication Number Publication Date
DE69841888D1 true DE69841888D1 (de) 2010-10-21

Family

ID=25420478

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69841888T Expired - Lifetime DE69841888D1 (de) 1997-08-01 1998-07-31 Gerät zur verabreichung von medikamenten und genen mittels elektroporation

Country Status (14)

Country Link
US (5) US6055453A (de)
EP (1) EP0999867B1 (de)
JP (2) JP2000503586A (de)
KR (1) KR100756252B1 (de)
CN (2) CN1768873B (de)
AT (1) ATE480294T1 (de)
AU (1) AU734343B2 (de)
BR (1) BR9806069A (de)
CA (1) CA2268026C (de)
DE (1) DE69841888D1 (de)
HK (1) HK1027049A1 (de)
RU (1) RU2195332C2 (de)
TW (1) TW396043B (de)
WO (1) WO1999006101A1 (de)

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