DE69919003D1 - Acetaminophen-formulierung mit verlängerter freisetzung - Google Patents

Acetaminophen-formulierung mit verlängerter freisetzung

Info

Publication number
DE69919003D1
DE69919003D1 DE69919003T DE69919003T DE69919003D1 DE 69919003 D1 DE69919003 D1 DE 69919003D1 DE 69919003 T DE69919003 T DE 69919003T DE 69919003 T DE69919003 T DE 69919003T DE 69919003 D1 DE69919003 D1 DE 69919003D1
Authority
DE
Germany
Prior art keywords
acetaminophen
extended release
dissolution
composition
acetaminophene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69919003T
Other languages
English (en)
Other versions
DE69919003T2 (de
Inventor
O Anaebonam
Emmett Clemente
W Mendes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medicis Pediatrics Inc
Original Assignee
Medicis Pediatrics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicis Pediatrics Inc filed Critical Medicis Pediatrics Inc
Publication of DE69919003D1 publication Critical patent/DE69919003D1/de
Application granted granted Critical
Publication of DE69919003T2 publication Critical patent/DE69919003T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
DE69919003T 1998-09-03 1999-09-03 Acetaminophen-formulierung mit verlängerter freisetzung Expired - Fee Related DE69919003T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/146,261 US6254891B1 (en) 1998-09-03 1998-09-03 Extended release acetaminophen
US146261 1998-09-03
PCT/US1999/020381 WO2000013670A1 (en) 1998-09-03 1999-09-03 Extended release acetaminophen

Publications (2)

Publication Number Publication Date
DE69919003D1 true DE69919003D1 (de) 2004-09-02
DE69919003T2 DE69919003T2 (de) 2005-08-04

Family

ID=22516565

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69919003T Expired - Fee Related DE69919003T2 (de) 1998-09-03 1999-09-03 Acetaminophen-formulierung mit verlängerter freisetzung

Country Status (9)

Country Link
US (1) US6254891B1 (de)
EP (2) EP1493434A1 (de)
AT (1) ATE271854T1 (de)
AU (2) AU5702799A (de)
CA (1) CA2339942C (de)
DE (1) DE69919003T2 (de)
ES (1) ES2230889T3 (de)
HK (1) HK1034903A1 (de)
WO (2) WO2000013669A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0009522D0 (en) 2000-04-19 2000-06-07 Smithkline Beecham Plc Composition
KR100522239B1 (ko) * 2002-07-16 2005-10-18 주식회사 서울제약 아세트아미노펜을 함유하는 제어방출성의 경구용 제제
AU2003300469A1 (en) * 2002-12-31 2004-07-29 Larry L. Augsburger Methods for making pharmaceutical dosage forms containing active cushioning components
US20040186180A1 (en) * 2003-03-21 2004-09-23 Gelotte Cathy K. Non-steroidal anti-inflammatory drug dosing regimen
KR101169614B1 (ko) * 2003-09-26 2012-08-03 알자 코포레이션 상승한 방출 속도를 나타내는 제어 방출 제제
ATE544447T1 (de) * 2003-09-26 2012-02-15 Alza Corp Arzneistoffcoating mit hohem wirkstoffanteil sowie methoden zu dessen herstellung
US20050089570A1 (en) * 2003-09-26 2005-04-28 Evangeline Cruz Oros push-stick for controlled delivery of active agents
US20050158382A1 (en) * 2003-09-26 2005-07-21 Evangeline Cruz Controlled release formulations of opioid and nonopioid analgesics
US20050095300A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
US20050095299A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
US8541026B2 (en) * 2004-09-24 2013-09-24 Abbvie Inc. Sustained release formulations of opioid and nonopioid analgesics
US20080057122A1 (en) * 2006-08-31 2008-03-06 Aaipharma Inc. Acetaminophen pharmaceutical compositions
PL3639828T3 (pl) 2013-12-24 2022-05-02 Virginia Commonwealth University Zastosowanie utlenowanych siarczanów cholesterolu (ocs) w leczeniu ostrej niewydolności wątroby
WO2016042570A1 (en) * 2014-09-16 2016-03-24 Suresh Pareek Extended release formulation of acetaminophen
AU2021242300A1 (en) * 2020-03-26 2022-10-13 Provectus Pharmatech, Inc. Novel uses of halogenated xanthenes in oncology and virology

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58110B1 (en) 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US4867984A (en) * 1984-11-06 1989-09-19 Nagin K. Patel Drug in bead form and process for preparing same
US4874613A (en) * 1987-03-06 1989-10-17 Baker Cummins Pharmaceuticals, Inc. Taste concealing pharmaceutical dosage unit
US4820522A (en) 1987-07-27 1989-04-11 Mcneilab, Inc. Oral sustained release acetaminophen formulation and process
US5032384A (en) 1989-01-27 1991-07-16 Block Drug Company, Inc. Compositions and method for the treatment of disease
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US5773031A (en) * 1996-02-27 1998-06-30 L. Perrigo Company Acetaminophen sustained-release formulation
US5780055A (en) * 1996-09-06 1998-07-14 University Of Maryland, Baltimore Cushioning beads and tablet comprising the same capable of forming a suspension

Also Published As

Publication number Publication date
ES2230889T3 (es) 2005-05-01
AU5810499A (en) 2000-03-27
EP1109535B1 (de) 2004-07-28
CA2339942A1 (en) 2000-03-16
EP1493434A1 (de) 2005-01-05
AU5702799A (en) 2000-03-27
DE69919003T2 (de) 2005-08-04
WO2000013669A1 (en) 2000-03-16
CA2339942C (en) 2007-05-22
US6254891B1 (en) 2001-07-03
HK1034903A1 (en) 2001-11-09
WO2000013670A1 (en) 2000-03-16
EP1109535A4 (de) 2002-03-13
ATE271854T1 (de) 2004-08-15
AU751180B2 (en) 2002-08-08
EP1109535A1 (de) 2001-06-27

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: MEDICIS PEDIATRICS, INC., SCOTTSDALE, ARIZ., US

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee