DE69927340D1 - Vorrichtung zur vernebelung einer flussigkeit in einem tragbaren inhalator - Google Patents

Vorrichtung zur vernebelung einer flussigkeit in einem tragbaren inhalator

Info

Publication number
DE69927340D1
DE69927340D1 DE69927340T DE69927340T DE69927340D1 DE 69927340 D1 DE69927340 D1 DE 69927340D1 DE 69927340 T DE69927340 T DE 69927340T DE 69927340 T DE69927340 T DE 69927340T DE 69927340 D1 DE69927340 D1 DE 69927340D1
Authority
DE
Germany
Prior art keywords
liquid
cartridge
illustrating
fluid
portable inhaler
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69927340T
Other languages
English (en)
Other versions
DE69927340T2 (de
Inventor
Yehuda Ivri
R Deyoung
H Wu
S Cater
Vijay Kumar
Markus Flierl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aerogen Inc
Original Assignee
Aerogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/095,737 external-priority patent/US6014970A/en
Application filed by Aerogen Inc filed Critical Aerogen Inc
Publication of DE69927340D1 publication Critical patent/DE69927340D1/de
Application granted granted Critical
Publication of DE69927340T2 publication Critical patent/DE69927340T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B17/00Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
    • B05B17/04Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
    • B05B17/06Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
    • B05B17/0607Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
    • B05B17/0653Details
    • B05B17/0676Feeding means
    • B05B17/0684Wicks or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0085Inhalators using ultrasonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/02Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
    • A61M15/025Bubble jet droplet ejection devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/109Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle the dispensing stroke being affected by the stored energy of a spring
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1094Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle having inlet or outlet valves not being actuated by pressure or having no inlet or outlet valve
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B12/00Arrangements for controlling delivery; Arrangements for controlling the spray area
    • B05B12/08Arrangements for controlling delivery; Arrangements for controlling the spray area responsive to condition of liquid or other fluent material to be discharged, of ambient medium or of target ; responsive to condition of spray devices or of supply means, e.g. pipes, pumps or their drive means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B17/00Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
    • B05B17/04Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
    • B05B17/06Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
    • B05B17/0607Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
    • B05B17/0638Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers spray being produced by discharging the liquid or other fluent material through a plate comprising a plurality of orifices
    • B05B17/0646Vibrating plates, i.e. plates being directly subjected to the vibrations, e.g. having a piezoelectric transducer attached thereto
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B41PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41JTYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J2/00Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
    • B41J2/005Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
    • B41J2/01Ink jet
    • B41J2/015Ink jet characterised by the jet generation process
    • B41J2/02Ink jet characterised by the jet generation process generating a continuous ink jet
    • B41J2/025Ink jet characterised by the jet generation process generating a continuous ink jet by vibration
    • CCHEMISTRY; METALLURGY
    • C25ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25DPROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D1/00Electroforming
    • C25D1/08Perforated or foraminous objects, e.g. sieves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • A61M2016/0033Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
    • A61M2016/0039Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the inspiratory circuit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0233Conductive materials, e.g. antistatic coatings for spark prevention
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3306Optical measuring means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/82Internal energy supply devices
    • A61M2205/8206Internal energy supply devices battery-operated
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/02Membranes or pistons acting on the contents inside the container, e.g. follower pistons
    • B05B11/028Pistons separating the content remaining in the container from the atmospheric air to compensate underpressure inside the container
DE69927340T 1998-06-11 1999-06-10 Vorrichtung zur vernebelung einer flussigkeit in einem tragbaren inhalator Expired - Lifetime DE69927340T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US09/095,737 US6014970A (en) 1998-06-11 1998-06-11 Methods and apparatus for storing chemical compounds in a portable inhaler
US95737 1998-06-11
US149426 1998-09-08
US09/149,426 US6205999B1 (en) 1995-04-05 1998-09-08 Methods and apparatus for storing chemical compounds in a portable inhaler
US09/313,914 US6755189B2 (en) 1995-04-05 1999-05-18 Methods and apparatus for storing chemical compounds in a portable inhaler
US313914 1999-05-18
PCT/US1999/013148 WO1999063946A2 (en) 1998-06-11 1999-06-10 Improved methods and apparatus for storing chemical compounds in a portable inhaler

Publications (2)

Publication Number Publication Date
DE69927340D1 true DE69927340D1 (de) 2005-10-27
DE69927340T2 DE69927340T2 (de) 2006-07-13

Family

ID=27377984

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69927340T Expired - Lifetime DE69927340T2 (de) 1998-06-11 1999-06-10 Vorrichtung zur vernebelung einer flussigkeit in einem tragbaren inhalator
DE69941828T Expired - Lifetime DE69941828D1 (de) 1998-06-11 1999-06-10 Aerosolerzeuger mit Vibrationsplatte

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69941828T Expired - Lifetime DE69941828D1 (de) 1998-06-11 1999-06-10 Aerosolerzeuger mit Vibrationsplatte

Country Status (14)

Country Link
US (3) US6205999B1 (de)
EP (3) EP2149359B1 (de)
JP (2) JP2002529114A (de)
CN (1) CN1303309A (de)
AT (2) ATE304833T1 (de)
AU (1) AU4560399A (de)
BR (1) BR9906489A (de)
CA (1) CA2300975C (de)
DE (2) DE69927340T2 (de)
ES (3) ES2401847T3 (de)
HK (1) HK1091394A1 (de)
MX (1) MXPA00001489A (de)
NZ (1) NZ502308A (de)
WO (1) WO1999063946A2 (de)

Families Citing this family (154)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6540154B1 (en) * 1991-04-24 2003-04-01 Aerogen, Inc. Systems and methods for controlling fluid feed to an aerosol generator
US6427682B1 (en) * 1995-04-05 2002-08-06 Aerogen, Inc. Methods and apparatus for aerosolizing a substance
US6782886B2 (en) 1995-04-05 2004-08-31 Aerogen, Inc. Metering pumps for an aerosolizer
US5758637A (en) 1995-08-31 1998-06-02 Aerogen, Inc. Liquid dispensing apparatus and methods
US6234167B1 (en) 1998-10-14 2001-05-22 Chrysalis Technologies, Incorporated Aerosol generator and methods of making and using an aerosol generator
US6235177B1 (en) 1999-09-09 2001-05-22 Aerogen, Inc. Method for the construction of an aperture plate for dispensing liquid droplets
MY136453A (en) * 2000-04-27 2008-10-31 Philip Morris Usa Inc "improved method and apparatus for generating an aerosol"
MXPA02010884A (es) * 2000-05-05 2003-03-27 Aerogen Ireland Ltd Aparato y metodo para el suministro de medicamentos al sistema respiratorio.
US7600511B2 (en) * 2001-11-01 2009-10-13 Novartis Pharma Ag Apparatus and methods for delivery of medicament to a respiratory system
US6948491B2 (en) * 2001-03-20 2005-09-27 Aerogen, Inc. Convertible fluid feed system with comformable reservoir and methods
US7100600B2 (en) * 2001-03-20 2006-09-05 Aerogen, Inc. Fluid filled ampoules and methods for their use in aerosolizers
US7971588B2 (en) * 2000-05-05 2011-07-05 Novartis Ag Methods and systems for operating an aerosol generator
US8336545B2 (en) * 2000-05-05 2012-12-25 Novartis Pharma Ag Methods and systems for operating an aerosol generator
US8122880B2 (en) * 2000-12-18 2012-02-28 Palo Alto Research Center Incorporated Inhaler that uses focused acoustic waves to deliver a pharmaceutical product
US7121275B2 (en) * 2000-12-18 2006-10-17 Xerox Corporation Method of using focused acoustic waves to deliver a pharmaceutical product
US7077130B2 (en) * 2000-12-22 2006-07-18 Chrysalis Technologies Incorporated Disposable inhaler system
US6491233B2 (en) 2000-12-22 2002-12-10 Chrysalis Technologies Incorporated Vapor driven aerosol generator and method of use thereof
US6501052B2 (en) 2000-12-22 2002-12-31 Chrysalis Technologies Incorporated Aerosol generator having multiple heating zones and methods of use thereof
US6799572B2 (en) 2000-12-22 2004-10-05 Chrysalis Technologies Incorporated Disposable aerosol generator system and methods for administering the aerosol
US6701921B2 (en) * 2000-12-22 2004-03-09 Chrysalis Technologies Incorporated Aerosol generator having heater in multilayered composite and method of use thereof
US6681998B2 (en) 2000-12-22 2004-01-27 Chrysalis Technologies Incorporated Aerosol generator having inductive heater and method of use thereof
US7073499B1 (en) 2001-02-06 2006-07-11 Injet Digital Aerosols Limited Inhaler with airflow regulation
US6546927B2 (en) 2001-03-13 2003-04-15 Aerogen, Inc. Methods and apparatus for controlling piezoelectric vibration
US6554201B2 (en) * 2001-05-02 2003-04-29 Aerogen, Inc. Insert molded aerosol generator and methods
US6732944B2 (en) * 2001-05-02 2004-05-11 Aerogen, Inc. Base isolated nebulizing device and methods
US6568390B2 (en) 2001-09-21 2003-05-27 Chrysalis Technologies Incorporated Dual capillary fluid vaporizing device
US6640050B2 (en) 2001-09-21 2003-10-28 Chrysalis Technologies Incorporated Fluid vaporizing device having controlled temperature profile heater/capillary tube
US6804458B2 (en) 2001-12-06 2004-10-12 Chrysalis Technologies Incorporated Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate
US6681769B2 (en) 2001-12-06 2004-01-27 Crysalis Technologies Incorporated Aerosol generator having a multiple path heater arrangement and method of use thereof
US6701922B2 (en) 2001-12-20 2004-03-09 Chrysalis Technologies Incorporated Mouthpiece entrainment airflow control for aerosol generators
EP1471960B1 (de) 2002-01-07 2019-03-13 Novartis AG Vorrichtungen zur vernebelung von flüssigkeiten zur inhalation
US7677467B2 (en) * 2002-01-07 2010-03-16 Novartis Pharma Ag Methods and devices for aerosolizing medicament
US20050205089A1 (en) * 2002-01-07 2005-09-22 Aerogen, Inc. Methods and devices for aerosolizing medicament
AU2003203043A1 (en) * 2002-01-15 2003-07-30 Aerogen, Inc. Methods and systems for operating an aerosol generator
GB2384198B (en) 2002-01-18 2005-03-02 Profile Drug Delivery Ltd Nebulizer metering
JP2005526769A (ja) * 2002-03-15 2005-09-08 ザ・ブリガーム・アンド・ウーメンズ・ホスピタル・インコーポレーテッド 治療剤を全身搬送するための中央気道投与
US20040063912A1 (en) * 2002-03-15 2004-04-01 The Brigham And Women's Hospital, Inc. Central airway administration for systemic delivery of therapeutics
HUE033736T2 (en) * 2002-03-22 2018-01-29 Clinical Designs Ltd Box assembly
US8245708B2 (en) * 2002-05-07 2012-08-21 The Research Foundation Of State University Of New York Methods, devices and formulations for targeted endobronchial therapy
US7607436B2 (en) * 2002-05-06 2009-10-27 The Research Foundation Of State University Of New York Methods, devices and formulations for targeted endobronchial therapy
WO2003095005A1 (en) * 2002-05-10 2003-11-20 Chrysalis Technologies Incorporated Aerosol generator for drug formulation and methods of generating aerosol
ES2572770T3 (es) * 2002-05-20 2016-06-02 Novartis Ag Aparato para proporcionar pulverización para tratamiento médico y métodos
US20070044792A1 (en) * 2005-08-30 2007-03-01 Aerogen, Inc. Aerosol generators with enhanced corrosion resistance
US6843430B2 (en) 2002-05-24 2005-01-18 S. C. Johnson & Son, Inc. Low leakage liquid atomization device
US20040055595A1 (en) * 2002-09-19 2004-03-25 Noymer Peter D. Aerosol drug delivery system employing formulation pre-heating
US6752327B2 (en) * 2002-10-16 2004-06-22 S. C. Johnson & Son, Inc. Atomizer with tilted orifice plate and replacement reservoir for same
GB2396825B (en) 2002-11-20 2004-12-08 Profile Respiratory Systems Lt Improved inhalation method and apparatus
GB2395437C (en) 2002-11-20 2010-10-20 Profile Respiratory Systems Ltd Improved inhalation method and apparatus
GB0304000D0 (en) * 2003-02-21 2003-03-26 Clinical Designs Ltd Dispenser
US8616195B2 (en) * 2003-07-18 2013-12-31 Novartis Ag Nebuliser for the production of aerosolized medication
GB2398065A (en) * 2003-10-16 2004-08-11 Bespak Plc Dispensing apparatus
GB0327112D0 (en) * 2003-11-21 2003-12-24 Clincial Designs Ltd Dispenser and reservoir
GB0328859D0 (en) * 2003-12-12 2004-01-14 Clinical Designs Ltd Dispenser and counter
MXPA06009516A (es) 2004-02-24 2007-03-26 Microdose Technologies Inc Inhalador con sensor de flujo direccional.
US7946291B2 (en) 2004-04-20 2011-05-24 Novartis Ag Ventilation systems and methods employing aerosol generators
US7267121B2 (en) * 2004-04-20 2007-09-11 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
US7290541B2 (en) * 2004-04-20 2007-11-06 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
CA2561403C (en) * 2004-04-20 2015-12-01 Aerogen, Inc. Aerosol delivery apparatus for pressure assisted breathing
EP1604701B1 (de) * 2004-06-09 2010-12-15 Microflow Engineering SA Verbessertes modulares Flüssigkeitssprühsystem
GB0425518D0 (en) * 2004-11-19 2004-12-22 Clinical Designs Ltd Substance source
US7827983B2 (en) * 2004-12-20 2010-11-09 Hewlett-Packard Development Company, L.P. Method for making a pharmaceutically active ingredient abuse-prevention device
GB0428204D0 (en) 2004-12-23 2005-01-26 Clinical Designs Ltd Medicament container
AU2006338285B8 (en) * 2005-02-09 2012-11-08 S3I, Llc Method and system for detecting, classifying and identifying particles
DE102005006375B4 (de) * 2005-02-11 2007-10-11 Pari GmbH Spezialisten für effektive Inhalation Aerosolerzeugungsvorrichtung für Inhalationstherapiegeräte
US20060198941A1 (en) * 2005-03-04 2006-09-07 Niall Behan Method of coating a medical appliance utilizing a vibrating mesh nebulizer, a system for coating a medical appliance, and a medical appliance produced by the method
US20060198942A1 (en) * 2005-03-04 2006-09-07 O'connor Timothy System and method for coating a medical appliance utilizing a vibrating mesh nebulizer
US20060198940A1 (en) * 2005-03-04 2006-09-07 Mcmorrow David Method of producing particles utilizing a vibrating mesh nebulizer for coating a medical appliance, a system for producing particles, and a medical appliance
CN101184522B (zh) 2005-05-18 2011-12-21 尼克塔治疗公司 用于支气管内治疗的阀、设备和方法
WO2006127181A2 (en) * 2005-05-25 2006-11-30 Aerogen, Inc. Vibration systems and methods
WO2007024812A1 (en) * 2005-08-23 2007-03-01 Aerogen, Inc. Self-sealing t-piece and valved t-piece
GB0518400D0 (en) 2005-09-09 2005-10-19 Clinical Designs Ltd Dispenser
JP2007130555A (ja) * 2005-11-09 2007-05-31 Tomotaka Koide 噴霧装置
TWM297751U (en) * 2006-03-21 2006-09-21 Taidoc Technology Corp Liquid nebulizer
TWI308615B (en) * 2006-06-20 2009-04-11 Ind Tech Res Inst Micro-pump and micro-pump system
DE102006030833A1 (de) * 2006-07-04 2008-01-10 Pari GmbH Spezialisten für effektive Inhalation Verfahren und Vorrichtung für die Reinigung der Verneblermembran in einem Inhalationstherapiegerät
GB0614621D0 (en) * 2006-07-24 2006-08-30 3M Innovative Properties Co Metered dose dispensers
GB0620700D0 (en) * 2006-10-19 2006-11-29 3M Innovative Properties Co Metered dose valves and dispensers
FR2908329B1 (fr) * 2006-11-14 2011-01-07 Telemaq Dispositif et methode de distribution de fluide par ultrasons
US20080110453A1 (en) * 2006-11-15 2008-05-15 Delphi Technologies Inc. Nebulizer and methods for controlling the nebulizer
US20080110452A1 (en) * 2006-11-15 2008-05-15 Delphi Technologies Inc. Nebulizer and method for controlling an amount of liquid that is atomized by the nebulizer
US20080156320A1 (en) * 2007-01-03 2008-07-03 Thomas Low Ultrasonic nebulizer and method for atomizing liquid
JP2008199905A (ja) * 2007-02-16 2008-09-04 Snow Brand Milk Prod Co Ltd 乳酸菌生残性向上剤
US20080252793A1 (en) * 2007-04-12 2008-10-16 Choi Ho-Yeol Media controller with anti-microbial and anti-fungal capability
MX2010003263A (es) * 2007-09-25 2010-06-02 Novartis Ag Tratamiento de trastornos pulmonares con medicamentos aerosolizados tales como vancomicina.
MX2010005789A (es) 2007-11-26 2010-06-09 Johnson & Son Inc S C Sistema de suministro de material volatil.
JP5383097B2 (ja) * 2008-01-25 2014-01-08 キヤノン株式会社 薬剤吐出装置及びその制御方法
JP5328242B2 (ja) * 2008-07-04 2013-10-30 キヤノン株式会社 薬剤吐出装置の洗浄装置
EP2344200A2 (de) * 2008-09-19 2011-07-20 Nektar Therapeutics Modifizierte therapeutische peptide, herstellungsverfahren und verwendung
AU2009292643B2 (en) * 2008-09-19 2016-02-18 Nektar Therapeutics Polymer conjugates of therapeutic peptides
PL2337600T3 (pl) 2008-09-26 2020-04-30 Stamford Devices Limited System podawania tlenu uzupełniającego
DE102008058725A1 (de) 2008-11-14 2010-05-20 Ing. Erich Pfeiffer Gmbh Austragvorrichtung
US9453652B2 (en) 2009-01-09 2016-09-27 S. C. Johnson & Son, Inc. Fragrance dispenser
DE102009010565B3 (de) * 2009-02-18 2010-09-02 Ing. Erich Pfeiffer Gmbh Austragvorrichtung
GB0904059D0 (en) 2009-03-10 2009-04-22 Euro Celtique Sa Counter
GB0904040D0 (en) 2009-03-10 2009-04-22 Euro Celtique Sa Counter
US20130255678A1 (en) * 2009-07-01 2013-10-03 Microdose Therapeutx, Inc. Nebulizer for infants and respiratory compromised patients
WO2011010282A1 (en) 2009-07-22 2011-01-27 Koninklijke Philips Electronics N.V. A nebulizer
JP5473532B2 (ja) * 2009-10-23 2014-04-16 株式会社オプトニクス精密 ノズル板、液体吐出ヘッド及び噴霧器
US9180261B2 (en) 2010-01-12 2015-11-10 Dance Biopharm Inc. Preservative free insulin formulations and systems and methods for aerosolizing
US10842951B2 (en) 2010-01-12 2020-11-24 Aerami Therapeutics, Inc. Liquid insulin formulations and methods relating thereto
US20130269684A1 (en) 2012-04-16 2013-10-17 Dance Pharmaceuticals, Inc. Methods and systems for supplying aerosolization devices with liquid medicaments
US9545488B2 (en) 2010-01-12 2017-01-17 Dance Biopharm Inc. Preservative-free single dose inhaler systems
US20160243199A1 (en) 2015-02-25 2016-08-25 Dance Biopharm, Inc. Liquid insulin formulations and methods relating thereto
US10857311B2 (en) 2010-01-12 2020-12-08 Omega Life Science Ltd. Method and apparatus for producing fine concentrated aerosol
CN102753148B (zh) 2010-02-11 2018-01-26 埃博灵克斯股份有限公司 用于制备气雾剂的方法和组合物
US8578942B2 (en) * 2010-05-25 2013-11-12 British American Tobacco (Investments) Limited Aerosol generator
DE102010024913A1 (de) 2010-06-15 2011-12-15 Ing. Erich Pfeiffer Gmbh Zerstäubervorrichtung
US10154923B2 (en) 2010-07-15 2018-12-18 Eyenovia, Inc. Drop generating device
US8689439B2 (en) 2010-08-06 2014-04-08 Abbott Laboratories Method for forming a tube for use with a pump delivery system
CN103153377A (zh) * 2010-09-30 2013-06-12 诺华有限公司 吸入器
US9717814B2 (en) 2010-10-01 2017-08-01 S. C. Johnson & Son, Inc. Dispensing device
US8377000B2 (en) 2010-10-01 2013-02-19 Abbott Laboratories Enteral feeding apparatus having a feeding set
US8377001B2 (en) 2010-10-01 2013-02-19 Abbott Laboratories Feeding set for a peristaltic pump system
EP3797874A1 (de) 2010-10-04 2021-03-31 Stamford Devices Limited Aerosolerzeuger
EP2658719B1 (de) 2010-12-28 2018-08-29 Stamford Devices Limited Lichtdefinierte aperturplatte und verfahren zu ihrer herstellung
US9068566B2 (en) 2011-01-21 2015-06-30 Biodot, Inc. Piezoelectric dispenser with a longitudinal transducer and replaceable capillary tube
EP3042982A1 (de) * 2011-12-21 2016-07-13 Stamford Devices Limited Aerosolerzeuger
JP5157000B1 (ja) * 2012-03-28 2013-03-06 田中貴金属工業株式会社 噴霧器用メッシュ
EP2644282B1 (de) 2012-03-28 2015-10-21 Tanaka Kikinzoku Kogyo K.K. Sieb-Zerstäuber und Herstellungsverfahren dafür
JP6385922B2 (ja) * 2012-06-11 2018-09-05 スタムフォード・ディバイセズ・リミテッド ネブライザのための開口板を製造する方法
US20140191063A1 (en) * 2013-01-08 2014-07-10 Serene House International Enterprise Ltd. Aromatic nebulizing diffuser
CA2882405C (en) 2013-03-15 2019-12-03 Trudell Medical International Ventilator circuit, adapter for use in ventilator circuit and methods for the use thereof
MX2015014490A (es) 2013-04-16 2016-08-11 Dance Biopharm Inc Distribucion de liquidos y metodos para distribuir liquidos.
EP2910268A1 (de) * 2014-02-25 2015-08-26 PARI Pharma GmbH Inhalator und Inhalatorsatz
US10279357B2 (en) 2014-05-23 2019-05-07 Stamford Devices Limited Method for producing an aperture plate
US10610651B2 (en) 2014-06-09 2020-04-07 Aerami Therapeutics, Inc. Self-puncturing liquid drug cartridges and associated dispenser
US10471222B2 (en) 2014-07-01 2019-11-12 Dance Biopharm Inc. Aerosolization system with flow restrictor and feedback device
US10857313B2 (en) 2014-07-01 2020-12-08 Aerami Therapeutics, Inc. Liquid nebulization systems and methods
US11273271B2 (en) 2014-07-01 2022-03-15 Aerami Therapeutics, Inc. Aerosolization system with flow restrictor and feedback device
WO2016059630A1 (en) 2014-10-13 2016-04-21 Omega Life Science Ltd. Nebulizers and uses thereof
CN104623771B (zh) * 2014-12-16 2017-06-16 中国人民解放军沈阳军区总医院 基因药物治疗流感或肺癌简易两用便携式定量雾化装置
WO2016116396A1 (de) * 2015-01-23 2016-07-28 Pari Pharma Gmbh Verfahren zur reinigung einer schwingungsfähigen membran eines membranaerosolgenerators und kombination aus reinigungsvorrichtung und reinigungsflüssigkeit für eine solche reinigung
CN104872820A (zh) * 2015-03-28 2015-09-02 深圳市杰仕博科技有限公司 雾化液的加热雾化装置
CN107735135B (zh) 2015-04-02 2020-06-26 希尔-罗姆服务私人有限公司 用于呼吸装置的歧管
GB201510451D0 (en) * 2015-06-15 2015-07-29 The Technology Partnership Plc Actuated-valve metering
KR102641177B1 (ko) 2015-07-20 2024-02-26 펄 테라퓨틱스 인코포레이티드 에어로졸 전달 시스템 및 관련 방법
GB2543065A (en) * 2015-10-06 2017-04-12 Thorn Security Smoke detector tester
JP7084309B2 (ja) 2016-02-08 2022-06-14 コーニンクレッカ フィリップス エヌ ヴェ エアゾール生成器
JP2019523213A (ja) 2016-05-02 2019-08-22 アブリンクス エン.ヴェー. Rsv感染の処置
WO2018071425A1 (en) 2016-10-11 2018-04-19 Microdose Therapeutx, Inc. Inhaler and methods of use thereof
WO2018099968A1 (en) 2016-11-29 2018-06-07 Ablynx N.V. Treatment of infection by respiratory syncytial virus (rsv)
CN106824607B (zh) * 2017-01-23 2018-12-21 重庆长安汽车股份有限公司 一种汽车涂装设备的外接增压稳压系统及工作方法
JP7007397B2 (ja) * 2017-03-20 2022-02-10 ヴェクトュラ・デリヴァリー・ディヴァイスィズ・リミテッド ネブライザの膜を洗浄するための容器
KR102326445B1 (ko) * 2017-03-20 2021-11-12 벡투라 딜리버리 디바이시스 리미티드 네뷸라이저의 멤브레인을 세정하기 위한 방법 및 용기
EP3600502B1 (de) * 2017-03-23 2021-09-29 Stamford Devices Ltd Aerosolabgabevorrichtung
US10987474B2 (en) 2017-03-23 2021-04-27 Stamford Devices Ltd. Retrofit aerosol delivery system and method
TWI615202B (zh) * 2017-04-26 2018-02-21 定量電灑噴霧裝置
EP3634550A4 (de) 2017-06-10 2021-03-03 Eyenovia, Inc. Verfahren und vorrichtungen zur handhabung einer flüssigkeit und zur abgabe der flüssigkeit an das auge
DE102017124742A1 (de) * 2017-10-23 2019-04-25 Nebu-Tec Med. Produkte Eike Kern Gmbh Automatische Medikamentendosierung bei Verneblern
CN108392706A (zh) * 2017-12-29 2018-08-14 合肥美菱净化设备有限公司 一种低频超声医用雾化器装置
CN108080203B (zh) * 2018-02-01 2023-10-27 佛山市顺德区雅洛特电器有限公司 一种超声雾化精油器
CN115444400A (zh) * 2018-03-05 2022-12-09 阿戈斯皮尔医疗公司 便携式吸入治疗的吸入和呼出测量装置及相关方法
US11406786B2 (en) 2019-04-22 2022-08-09 Sunovion Pharmaceuticals Inc. Nebulizer monitoring device, system and method
WO2020225663A1 (en) * 2019-05-07 2020-11-12 3M Innovative Properties Company Inhaler and method of detecting obstruction

Family Cites Families (176)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2101304A (en) 1936-06-05 1937-12-07 Sheaffer W A Pen Co Fountain pen
US2187528A (en) 1937-06-07 1940-01-16 Russell T Wing Fountain pen
US2158615A (en) 1937-07-26 1939-05-16 Sheaffer W A Pen Co Fountain pen
US2266706A (en) 1938-08-06 1941-12-16 Stanley L Fox Nasal atomizing inhaler and dropper
NL62585C (de) 1939-01-06
US2292381A (en) 1940-12-24 1942-08-11 Esterbrook Steel Pen Mfg Co Fountain pen feed
US2283333A (en) 1941-05-22 1942-05-19 Sheaffer W A Pen Co Fountain pen
US2375770A (en) 1943-11-19 1945-05-15 Arthur O Dahiberg Fountain pen
US2430023A (en) 1944-01-27 1947-11-04 Esterbrook Pen Co Writing implement
NL63900C (de) 1944-04-10
US2404063A (en) 1944-04-27 1946-07-16 Parker Pen Co Fountain pen
US2521657A (en) 1944-07-07 1950-09-05 Scripto Inc Fountain pen
US2512004A (en) 1945-03-05 1950-06-20 Russell T Wing Fountain pen
US2474996A (en) 1945-10-12 1949-07-05 Sheaffer W A Pen Co Fountain pen
BE473698A (de) 1946-06-08
US2779623A (en) 1954-09-10 1957-01-29 Bernard J Eisenkraft Electromechanical atomizer
US2935970A (en) 1955-03-23 1960-05-10 Sapphire Products Inc Fountain pen ink reservoir
GB973458A (en) 1962-10-16 1964-10-28 Exxon Research Engineering Co Improvements in or relating to methods and apparatus for atomising liquids
DE1461628A1 (de) 1965-04-30 1969-03-27 Montblanc Simplo Gmbh Tintenleiter fuer Fuellfederhalter
DE1575050A1 (de) 1966-01-12 1972-04-13 Misto Gen Equipment Co Ultraschall-Nebelerzeugungsgeraet
US3738637A (en) 1968-03-01 1973-06-12 Goldsworthy Eng Inc Method and apparatus for filament winding about three axes of a mandrel and products produced thereby
US3558052A (en) 1968-10-31 1971-01-26 F I N D Inc Method and apparatus for spraying electrostatic dry powder
US3738574A (en) 1971-06-15 1973-06-12 Siemens Ag Apparatus for atomizing fluids with a piezoelectrically stimulated oscillator system
NO134730L (de) 1971-07-19 1900-01-01
US3983740A (en) 1971-12-07 1976-10-05 Societe Grenobloise D'etudes Et D'applications Hydrauliques (Sogreah) Method and apparatus for forming a stream of identical drops at very high speed
US3790079A (en) 1972-06-05 1974-02-05 Rnb Ass Inc Method and apparatus for generating monodisperse aerosol
US3812854A (en) 1972-10-20 1974-05-28 A Michaels Ultrasonic nebulizer
AT323114B (de) 1973-05-07 1975-06-25 Voest Ag Verfahren zum prillen
US3804329A (en) 1973-07-27 1974-04-16 J Martner Ultrasonic generator and atomizer apparatus and method
DE2361781A1 (de) 1973-12-12 1975-06-19 Philips Patentverwaltung Schreibwerk zum schreiben mit fluessiger farbe
US3958249A (en) 1974-12-18 1976-05-18 International Business Machines Corporation Ink jet drop generator
US4005435A (en) 1975-05-15 1977-01-25 Burroughs Corporation Liquid jet droplet generator
DE2537765B2 (de) 1975-08-25 1981-04-09 Siemens AG, 1000 Berlin und 8000 München Medizinisches Inhalationsgerät zur Behandlung von Krankheiten der Atmungswege
GB1495910A (en) * 1975-10-30 1977-12-21 Ibm Method and bath for electroplating palladium on an articl
GB1524748A (en) * 1976-05-28 1978-09-13 Inco Europ Ltd Production of hard heat-resistant nickel-base electrodeposits
DE2703801C3 (de) * 1977-01-29 1979-08-02 W.C. Heraeus Gmbh, 6450 Hanau Gegen glasige Schmelzen beständige Legierungen
US4159803A (en) 1977-03-31 1979-07-03 MistO2 Gen Equipment Company Chamber for ultrasonic aerosol generation
US4268460A (en) 1977-12-12 1981-05-19 Warner-Lambert Company Nebulizer
DE2811248C3 (de) 1978-03-15 1981-11-26 Bosch-Siemens Hausgeräte GmbH, 7000 Stuttgart Flüssigkeitszerstäuber
US4338576A (en) 1978-07-26 1982-07-06 Tdk Electronics Co., Ltd. Ultrasonic atomizer unit utilizing shielded and grounded elements
US4240081A (en) 1978-10-13 1980-12-16 Dennison Manufacturing Company Ink jet printing
DE2849493C2 (de) 1978-11-15 1982-01-14 Carl Heyer Gmbh, Inhalationstechnik, 5427 Bad Ems In der Hand zu haltender Aerosolspender
DE2854841C2 (de) 1978-12-19 1981-03-26 Bosch-Siemens Hausgeräte GmbH, 7000 Stuttgart Flüssigkeitszerstäuber, vorzugsweise Inhalationsgerät
DE2907348A1 (de) 1979-02-24 1980-09-04 Boehringer Sohn Ingelheim Verbesserte inhalationsgeraete
US4226236A (en) * 1979-05-07 1980-10-07 Abbott Laboratories Prefilled, vented two-compartment syringe
DE7917568U1 (de) 1979-06-19 1979-09-20 Bosch-Siemens Hausgeraete Gmbh, 7000 Stuttgart Inhalationsgeraet
JPS5689569A (en) 1979-12-19 1981-07-20 Canon Inc Ink jet recording head
DE3010178C2 (de) 1980-03-17 1985-10-03 Kraftwerk Union AG, 4330 Mülheim Mit einem Schnellschlußventil ausgerüstete Schlitzdüse zur Herbeiführung impulsartiger Gasströmungen
US4402458A (en) 1980-04-12 1983-09-06 Battelle-Institut E.V. Apparatus for atomizing liquids
US4336544A (en) 1980-08-18 1982-06-22 Hewlett-Packard Company Method and apparatus for drop-on-demand ink jet printing
CA1178191A (en) 1980-10-06 1984-11-20 Naoyoshi Maehara Electric liquid atomizing apparatus
US4474251A (en) 1980-12-12 1984-10-02 Hydronautics, Incorporated Enhancing liquid jet erosion
US4389071A (en) 1980-12-12 1983-06-21 Hydronautics, Inc. Enhancing liquid jet erosion
US4454877A (en) 1981-05-26 1984-06-19 Andrew Boettner Portable nebulizer or mist producing device
NL8202263A (nl) 1981-06-06 1983-01-03 Rowenta Werke Gmbh Ultrasonore respirator.
US4408719A (en) 1981-06-17 1983-10-11 Last Anthony J Sonic liquid atomizer
US4475113A (en) 1981-06-18 1984-10-02 International Business Machines Drop-on-demand method and apparatus using converging nozzles and high viscosity fluids
JPS5861857A (ja) 1981-10-09 1983-04-13 Matsushita Electric Works Ltd 液体噴霧器
AU553251B2 (en) 1981-10-15 1986-07-10 Matsushita Electric Industrial Co., Ltd. Arrangement for ejecting liquid
US4474326A (en) 1981-11-24 1984-10-02 Tdk Electronics Co., Ltd. Ultrasonic atomizing device
CA1206996A (en) 1982-01-18 1986-07-02 Naoyoshi Maehara Ultrasonic liquid ejecting apparatus
US5073484A (en) 1982-03-09 1991-12-17 Bio-Metric Systems, Inc. Quantitative analysis apparatus and method
DE3311956A1 (de) 1982-03-31 1983-10-13 Ricoh Co., Ltd., Tokyo Farbstrahl-druckerkopf
JPS5912775A (ja) 1982-07-14 1984-01-23 Matsushita Electric Ind Co Ltd 霧化ポンプユニツト
DE3229921A1 (de) 1982-08-11 1984-02-16 Linde Ag, 6200 Wiesbaden Verfahren zum gleichzeitigen befuellen von mehreren mit acetylen gefuellten flaschen mit loesungsmitteln
US5002582A (en) 1982-09-29 1991-03-26 Bio-Metric Systems, Inc. Preparation of polymeric surfaces via covalently attaching polymers
US4722906A (en) 1982-09-29 1988-02-02 Bio-Metric Systems, Inc. Binding reagents and methods
US4973493A (en) 1982-09-29 1990-11-27 Bio-Metric Systems, Inc. Method of improving the biocompatibility of solid surfaces
US5217492A (en) 1982-09-29 1993-06-08 Bio-Metric Systems, Inc. Biomolecule attachment to hydrophobic surfaces
US5258041A (en) 1982-09-29 1993-11-02 Bio-Metric Systems, Inc. Method of biomolecule attachment to hydrophobic surfaces
US5512329A (en) 1982-09-29 1996-04-30 Bsi Corporation Substrate surface preparation
IT1156090B (it) 1982-10-26 1987-01-28 Olivetti & Co Spa Metodo e dispositivo di stampa a getto d inchiostro
US4632311A (en) 1982-12-20 1986-12-30 Matsushita Electric Industrial Co., Ltd. Atomizing apparatus employing a capacitive piezoelectric transducer
DE3320441A1 (de) 1983-06-06 1984-12-06 Siemens AG, 1000 Berlin und 8000 München Mit fluessigkeitstroepfchen arbeitendes schreibgeraet mit an beiden enden starr mit einer duesenplatte verbundenen stabfoermigen piezoelektrischen wandlern
ATE27405T1 (de) 1983-08-02 1987-06-15 Trutek Research Inc Beatmungsventil.
US4544933A (en) 1983-09-20 1985-10-01 Siemens Aktiengesellschaft Apparatus and method for ink droplet ejection for a printer
US4593291A (en) 1984-04-16 1986-06-03 Exxon Research And Engineering Co. Method for operating an ink jet device to obtain high resolution printing
US4575406A (en) * 1984-07-23 1986-03-11 Polaroid Corporation Microporous filter
DE3574344D1 (en) 1984-08-29 1989-12-28 Omron Tateisi Electronics Co Ultrasonic atomizer
US4628890A (en) 1984-08-31 1986-12-16 Freeman Winifer W Fuel atomizer
DE3582287D1 (de) 1984-09-07 1991-05-02 Omron Tateisi Electronics Co Schwingungserzeuger fuer ein inhalationsgeraet mit ultraschallzerstaeubung.
US4826759A (en) 1984-10-04 1989-05-02 Bio-Metric Systems, Inc. Field assay for ligands
NZ209900A (en) 1984-10-16 1989-08-29 Univ Auckland Automatic inhaler
US4550325A (en) 1984-12-26 1985-10-29 Polaroid Corporation Drop dispensing device
DE3500985A1 (de) 1985-01-14 1986-07-17 Siemens AG, 1000 Berlin und 8000 München Anordnung zur erzeugung von einzeltroepfchen in tintenschreibeinrichtungen
JPS61215059A (ja) 1985-03-22 1986-09-24 Toshiba Corp インクジエツト記録装置
DE3524701A1 (de) 1985-07-11 1987-01-15 Bosch Gmbh Robert Ultraschallzerstaeuberduese
US4659014A (en) 1985-09-05 1987-04-21 Delavan Corporation Ultrasonic spray nozzle and method
US4702418A (en) 1985-09-09 1987-10-27 Piezo Electric Products, Inc. Aerosol dispenser
US4753579A (en) 1986-01-22 1988-06-28 Piezo Electric Products, Inc. Ultrasonic resonant device
US4799622A (en) 1986-08-05 1989-01-24 Tao Nenryo Kogyo Kabushiki Kaisha Ultrasonic atomizing apparatus
DE3627222A1 (de) 1986-08-11 1988-02-18 Siemens Ag Ultraschall-taschenzerstaeubergeraet
US4979959A (en) 1986-10-17 1990-12-25 Bio-Metric Systems, Inc. Biocompatible coating for solid surfaces
US5263992A (en) 1986-10-17 1993-11-23 Bio-Metric Systems, Inc. Biocompatible device with covalently bonded biocompatible agent
DE3637631C1 (de) 1986-11-05 1987-08-20 Philips Patentverwaltung Verfahren zum Aufbringen kleiner schmelzfluessiger,tropfenfoermiger Lotmengen aus einer Duese auf zu benetzende Flaechen und Vorrichtung zur Durchfuehrung des Verfahrens
US4976259A (en) 1986-12-22 1990-12-11 Mountain Medical Equipment, Inc. Ultrasonic nebulizer
NL8603278A (nl) * 1986-12-23 1988-07-18 Stork Veco Bv Membraan met perforaties en werkwijze voor het vervaardigen van een dergelijk membraan.
EP0282616B1 (de) 1987-03-17 1989-10-04 Lechler GmbH & Co.KG Ultraschall-Flüssigkeitszerstäuber
JPS63230957A (ja) 1987-03-20 1988-09-27 Hitachi Ltd 液体微粒化装置
US4850534A (en) 1987-05-30 1989-07-25 Tdk Corporation Ultrasonic wave nebulizer
EP0295337B1 (de) * 1987-06-16 1991-12-04 Akzo Nobel N.V. Zweikammer-Spritze und Herstellungsverfahren
IL86799A (en) * 1987-07-02 1993-03-15 Kabi Pharmacia Ab Method and device for injection
DE3724629A1 (de) 1987-07-22 1989-02-02 Siemens Ag Piezoelektrisch anregbares resonanzsystem
US5139016A (en) 1987-08-07 1992-08-18 Sorin Biomedica S.P.A. Process and device for aerosol generation for pulmonary ventilation scintigraphy
FI82808C (fi) 1987-12-31 1991-04-25 Etelae Haemeen Keuhkovammayhdi Ultraljudfinfoerdelningsanordning.
US4826886A (en) 1988-05-26 1989-05-02 Ethyl Corporation Polyimide foams and their production
US5021701A (en) 1988-10-20 1991-06-04 Tdk Corporation Piezoelectric vibrator mounting system for a nebulizer
US4911798A (en) * 1988-12-20 1990-03-27 At&T Bell Laboratories Palladium alloy plating process
JPH02269058A (ja) 1989-03-14 1990-11-02 Seiko Epson Corp レーリーモード弾性表面波による液滴ジェット装置
WO1990012655A1 (en) 1989-04-14 1990-11-01 Azerbaidzhansky Politekhnichesky Institut Imeni Ch.Ildryma Device for ultrasonic dispersion of a liquid medium
US5024733A (en) * 1989-08-29 1991-06-18 At&T Bell Laboratories Palladium alloy electroplating process
US5227168A (en) * 1989-11-21 1993-07-13 Bruce Barber Method of treating a wound
US5152456A (en) 1989-12-12 1992-10-06 Bespak, Plc Dispensing apparatus having a perforate outlet member and a vibrating device
US4954225A (en) * 1990-01-10 1990-09-04 Dynamics Research Corporation Method for making nozzle plates
DE59001705D1 (de) * 1990-02-07 1993-07-15 Vetter & Co Apotheker Doppelkammerspritze und verwendungsverfahren.
GB9015077D0 (en) 1990-07-09 1990-08-29 Riker Laboratories Inc Inhaler
FR2665849B1 (fr) 1990-08-20 1995-03-24 Dynamad Dispositif ultrasonique pour la production en continu de particules.
US5115803A (en) 1990-08-31 1992-05-26 Minnesota Mining And Manufacturing Company Aerosol actuator providing increased respirable fraction
GB9020555D0 (en) 1990-09-20 1990-10-31 Bespak Plc Dispensing apparatus
DE69117127T2 (de) 1990-10-11 1996-11-07 Toda Koji Ultraschall-Zerstäuber
DE69127826T2 (de) 1990-12-17 1998-04-09 Minnesota Mining & Mfg Inhalationsgerät
EP0502723B1 (de) 1991-03-05 1996-10-09 Hitachi Chemical Co., Ltd. Wasserlösliche Tetrazaporphin und Fluoreszenzmarkierungsstoff
US5186164A (en) * 1991-03-15 1993-02-16 Puthalath Raghuprasad Mist inhaler
US5164740A (en) 1991-04-24 1992-11-17 Yehuda Ivri High frequency printing mechanism
US6629646B1 (en) * 1991-04-24 2003-10-07 Aerogen, Inc. Droplet ejector with oscillating tapered aperture
US5938117A (en) * 1991-04-24 1999-08-17 Aerogen, Inc. Methods and apparatus for dispensing liquids as an atomized spray
DE69210096T2 (de) 1991-05-27 1996-09-19 Tdk Corp Ultraschallzerstäuber
JPH0614756Y2 (ja) * 1991-06-26 1994-04-20 株式会社アルテ 組み立て式の2室式容器兼用注射器
AU662919B2 (en) 1991-07-02 1995-09-21 Inhale, Inc. Method and device for delivering aerosolized medicaments
US5180482A (en) 1991-07-22 1993-01-19 At&T Bell Laboratories Thermal annealing of palladium alloys
US5601077A (en) 1991-08-07 1997-02-11 Becton, Dickinson And Company Nasal syringe sprayer with removable dose limiting structure
DE4127650C1 (de) * 1991-08-21 1993-02-25 Arzneimittel Gmbh Apotheker Vetter & Co Ravensburg, 7980 Ravensburg, De
US5170782A (en) 1991-09-12 1992-12-15 Devilbiss Health Care, Inc. Medicament nebulizer with improved aerosol chamber
DE69206824C5 (de) 1991-12-04 2009-07-09 The Technology Partnership PLC, Melbourn, Royston Vorrichtung und verfahren zur erzeugung von fluessigkeitstroepfchen
DE69218901T2 (de) 1991-12-10 1997-07-17 Tdk Corp Ultraschallzerstäuber
DE69328523T2 (de) 1992-02-13 2000-09-21 Surmodics Inc Immobilisierung eines chemischen spezies in einer vernetzten matrix
US5186166A (en) 1992-03-04 1993-02-16 Riggs John H Powder nebulizer apparatus and method of nebulization
DE69333443T2 (de) * 1992-04-09 2005-03-24 Omron Healthcare Co., Ltd. Ultraschallzerstäuber
US5512474A (en) 1992-05-29 1996-04-30 Bsi Corporation Cell culture support containing a cell adhesion factor and a positively-charged molecule
US5431155A (en) * 1992-06-03 1995-07-11 Elettro Plastica S.P.A. Single-dose nasal dispenser for atomized liquid drugs
FR2692569B1 (fr) 1992-06-18 1996-08-30 Valois Procede et dispositif de remplissage d'un distributeur doseur de substance fluide.
US5531683A (en) * 1992-08-13 1996-07-02 Science Incorporated Mixing and delivery syringe assembly
GB2272389B (en) 1992-11-04 1996-07-24 Bespak Plc Dispensing apparatus
US5414075A (en) 1992-11-06 1995-05-09 Bsi Corporation Restrained multifunctional reagent for surface modification
US5346132A (en) * 1992-11-12 1994-09-13 Gary S. Hahn Mist generator
US5452711A (en) * 1992-12-24 1995-09-26 Exar Corporation Small form factor atomizer
US6012450A (en) * 1993-01-29 2000-01-11 Aradigm Corporation Intrapulmonary delivery of hematopoietic drug
GB9305975D0 (en) 1993-03-23 1993-05-12 Minnesota Mining & Mfg Metered-dose aerosol valves
JPH06320084A (ja) * 1993-05-14 1994-11-22 Mikuni Corp 超音波噴霧振動板
US5497763A (en) * 1993-05-21 1996-03-12 Aradigm Corporation Disposable package for intrapulmonary delivery of aerosolized formulations
FR2705911B1 (fr) * 1993-06-02 1995-08-11 Oreal Appareil de nébulisation piézoélectrique.
GB2279571A (en) 1993-06-14 1995-01-11 Minnesota Mining & Mfg Inhaler
CH686872A5 (de) 1993-08-09 1996-07-31 Disetronic Ag Medizinisches Inhalationsgeraet.
US5818479A (en) * 1993-09-03 1998-10-06 Microparts Gmbh Nozzle plate for a liquid jet print head
US5415161A (en) 1993-09-15 1995-05-16 Ryder; Steven L. Intermittant demand aerosol control device
US5431992A (en) 1993-11-05 1995-07-11 Houpt; Ronald A. Dual-glass fibers and insulation products therefrom
GB9324250D0 (en) 1993-11-25 1994-01-12 Minnesota Mining & Mfg Inhaler
US5489266A (en) * 1994-01-25 1996-02-06 Becton, Dickinson And Company Syringe assembly and method for lyophilizing and reconstituting injectable medication
US5579757A (en) 1994-02-02 1996-12-03 Baxter International, Inc. Anti-siphon flow restricter for a nebulizer
US5435282A (en) * 1994-05-19 1995-07-25 Habley Medical Technology Corporation Nebulizer
FR2722765B1 (fr) 1994-07-25 1996-08-23 Oreal Recipient permettant le stockage d'au moins deux produits, le melange de ces produits et la distribution du melange ainsi obtenu
US5707818A (en) 1994-12-13 1998-01-13 Bsi Corporation Device and method for simultaneously performing multiple competitive immunoassays
US5685491A (en) 1995-01-11 1997-11-11 Amtx, Inc. Electroformed multilayer spray director and a process for the preparation thereof
NO950760L (no) 1995-02-28 1996-08-29 Elkem Materials Fremgangsmåte for fremstilling av alkylhalosilaner
US5533497A (en) 1995-03-27 1996-07-09 Ryder; Steven L. Sidestream aerosol generator and method in variable positions
US6427682B1 (en) * 1995-04-05 2002-08-06 Aerogen, Inc. Methods and apparatus for aerosolizing a substance
US5586550A (en) 1995-08-31 1996-12-24 Fluid Propulsion Technologies, Inc. Apparatus and methods for the delivery of therapeutic liquids to the respiratory system
US5758637A (en) * 1995-08-31 1998-06-02 Aerogen, Inc. Liquid dispensing apparatus and methods
WO1996037165A1 (en) 1995-05-26 1996-11-28 Bsi Corporation Method and implantable article for promoting endothelialization
US5654007A (en) 1995-06-07 1997-08-05 Inhale Therapeutic Systems Methods and system for processing dispersible fine powders
US5639851A (en) 1995-10-02 1997-06-17 Ethicon, Inc. High strength, melt processable, lactide-rich, poly(lactide-CO-P-dioxanone) copolymers
US5714360A (en) 1995-11-03 1998-02-03 Bsi Corporation Photoactivatable water soluble cross-linking agents containing an onium group
US5976344A (en) * 1996-05-10 1999-11-02 Lucent Technologies Inc. Composition for electroplating palladium alloys and electroplating process using that composition
US6145963A (en) * 1997-08-29 2000-11-14 Hewlett-Packard Company Reduced size printhead for an inkjet printer
US6037587A (en) * 1997-10-17 2000-03-14 Hewlett-Packard Company Chemical ionization source for mass spectrometry
US6235177B1 (en) * 1999-09-09 2001-05-22 Aerogen, Inc. Method for the construction of an aperture plate for dispensing liquid droplets

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EP1009363A2 (de) 2000-06-21
US6755189B2 (en) 2004-06-29
EP2149359B1 (de) 2013-01-30
WO1999063946A2 (en) 1999-12-16
EP1632210A3 (de) 2006-03-15
CN1303309A (zh) 2001-07-11
JP2008289903A (ja) 2008-12-04
EP1632210B1 (de) 2009-12-16
ES2401847T3 (es) 2013-04-25
US20020011247A1 (en) 2002-01-31
US20020023639A1 (en) 2002-02-28
JP5552219B2 (ja) 2014-07-16
EP2149359A1 (de) 2010-02-03
WO1999063946A3 (en) 2000-02-03
US8578931B2 (en) 2013-11-12
ATE304833T1 (de) 2005-10-15
ES2251834T3 (es) 2006-05-01
MXPA00001489A (es) 2004-05-21
CA2300975C (en) 2006-09-19
DE69941828D1 (de) 2010-01-28
AU4560399A (en) 1999-12-30
NZ502308A (en) 2002-02-01
JP2002529114A (ja) 2002-09-10
EP1009363A4 (de) 2002-11-20
HK1091394A1 (en) 2007-01-19
EP1632210A2 (de) 2006-03-08
US6205999B1 (en) 2001-03-27
BR9906489A (pt) 2001-08-21
CA2300975A1 (en) 1999-12-16
DE69927340T2 (de) 2006-07-13
ATE451905T1 (de) 2010-01-15
EP1009363B1 (de) 2005-09-21
ES2338337T3 (es) 2010-05-06

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