DE69941390D1 - Diacylglyzerin-acyltransferase proteine - Google Patents
Diacylglyzerin-acyltransferase proteineInfo
- Publication number
- DE69941390D1 DE69941390D1 DE69941390T DE69941390T DE69941390D1 DE 69941390 D1 DE69941390 D1 DE 69941390D1 DE 69941390 T DE69941390 T DE 69941390T DE 69941390 T DE69941390 T DE 69941390T DE 69941390 D1 DE69941390 D1 DE 69941390D1
- Authority
- DE
- Germany
- Prior art keywords
- dagat
- proteins
- methods
- diacylglyzerine
- triacylglycerol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9163198P | 1998-07-02 | 1998-07-02 | |
US13082999P | 1999-04-23 | 1999-04-23 | |
PCT/US1999/015243 WO2000001713A2 (en) | 1998-07-02 | 1999-06-30 | Diacylglycerol acyl transferase proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69941390D1 true DE69941390D1 (de) | 2009-10-22 |
Family
ID=26784169
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69941390T Expired - Lifetime DE69941390D1 (de) | 1998-07-02 | 1999-06-30 | Diacylglyzerin-acyltransferase proteine |
Country Status (8)
Country | Link |
---|---|
US (1) | US6822141B2 (de) |
EP (1) | EP1098962B1 (de) |
JP (1) | JP4514952B2 (de) |
AT (1) | ATE442435T1 (de) |
BR (1) | BR9911800A (de) |
CA (1) | CA2331329C (de) |
DE (1) | DE69941390D1 (de) |
WO (1) | WO2000001713A2 (de) |
Families Citing this family (110)
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US6936289B2 (en) | 1995-06-07 | 2005-08-30 | Danisco A/S | Method of improving the properties of a flour dough, a flour dough improving composition and improved food products |
DE69827172T2 (de) * | 1997-04-09 | 2006-02-23 | Danisco A/S | Lipase und Verwendung davon zur Verbesserung von Teigen und Backwaren |
US7135617B2 (en) | 1998-07-02 | 2006-11-14 | Calgene Llc | Diacylglycerol acyl transferase proteins |
ATE231186T1 (de) * | 1998-07-21 | 2003-02-15 | Danisco | Lebensmittel |
EP1141324B1 (de) * | 1998-12-17 | 2006-09-27 | National Research Council Of Canada | Diacylglyzerin-acyltransferase gen aus pflanzen |
US7015373B1 (en) | 1998-12-17 | 2006-03-21 | National Research Council Of Canada | Diacylglycerol acyltransferase gene from plants |
US6995301B1 (en) | 1999-05-04 | 2006-02-07 | Cargill, Incorporated | Plant acyltransferases |
AU784352B2 (en) * | 1999-05-04 | 2006-03-16 | Cargill Incorporated | Plant acyltransferases |
US6552250B1 (en) | 2000-06-14 | 2003-04-22 | Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food | Diacylglycerol O-acyltransferase |
US6444427B1 (en) * | 2000-07-11 | 2002-09-03 | The Regents Of The University Of California | Polymorphisms in a diacylglycerol acyltransferase gene, and methods of use thereof |
US7045326B2 (en) | 2001-02-23 | 2006-05-16 | The Regents Of The University Of California | Mono- and diacylglycerol acyltransferases and methods of use thereof |
US20020119138A1 (en) | 2001-02-26 | 2002-08-29 | Sylvaine Cases | Diacylglycerol o-acyltransferase 2alpha (DGAT2alpha) |
SE0101317D0 (sv) * | 2001-04-12 | 2001-04-12 | Pharmacia Ab | Protein cluster v |
NZ528260A (en) | 2001-05-18 | 2005-09-30 | Danisco | Method of improving dough and bread quality with the addition of an enzyme that hydrolyses a glycolipid and a phospholipid and incapable of hydrolysing a triglyceride or monoglyceride |
US7566813B2 (en) | 2002-03-21 | 2009-07-28 | Monsanto Technology, L.L.C. | Nucleic acid constructs and methods for producing altered seed oil compositions |
CA2492205A1 (en) | 2002-07-31 | 2004-02-05 | Monsanto Technology, Llc | Diacylglycerol acyltransferase nucleic acid sequences and associated products |
US7078234B2 (en) | 2002-12-18 | 2006-07-18 | Monsanto Technology Llc | Maize embryo-specific promoter compositions and methods for use thereof |
US20050196766A1 (en) * | 2003-12-24 | 2005-09-08 | Soe Jorn B. | Proteins |
US7955814B2 (en) * | 2003-01-17 | 2011-06-07 | Danisco A/S | Method |
MXPA05007654A (es) | 2003-01-17 | 2005-09-30 | Danisco | Metodo. |
WO2004065551A2 (en) * | 2003-01-21 | 2004-08-05 | Bristol-Myers Squibb Company | Polynucleotide encoding a novel acyl coenzyme a, monoacylglycerol acyltransferase-3 (mgat3), and uses thereof |
US20040185559A1 (en) | 2003-03-21 | 2004-09-23 | Isis Pharmaceuticals Inc. | Modulation of diacylglycerol acyltransferase 1 expression |
US7294760B2 (en) | 2003-03-28 | 2007-11-13 | Monsanto Technology Llc | Plant promoters for use in early seed development |
AR044152A1 (es) | 2003-05-09 | 2005-08-24 | Bayer Corp | Derivados de alquilarilo, metodo de preparacion y uso para el tratamiento de la obesidad |
US7267976B2 (en) | 2003-07-02 | 2007-09-11 | E.I. Du Pont De Nemours And Company | Acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous yeasts |
US7825235B2 (en) | 2003-08-18 | 2010-11-02 | Isis Pharmaceuticals, Inc. | Modulation of diacylglycerol acyltransferase 2 expression |
US7718408B2 (en) | 2003-12-24 | 2010-05-18 | Danisco A/S | Method |
US7906307B2 (en) | 2003-12-24 | 2011-03-15 | Danisco A/S | Variant lipid acyltransferases and methods of making |
GB0716126D0 (en) | 2007-08-17 | 2007-09-26 | Danisco | Process |
EP1718663B1 (de) | 2004-01-20 | 2011-07-13 | Monsanto Technology, LLC | Chimäre promotoren zur verwendung in pflanzen |
GB0405637D0 (en) * | 2004-03-12 | 2004-04-21 | Danisco | Protein |
MX2007000626A (es) * | 2004-07-16 | 2007-03-07 | Danisco | Enzima lipolitica; usos de la misma en la industria alimenticia. |
CA2580061C (en) | 2004-09-13 | 2014-11-25 | Monsanto Technology Llc | Promoters for regulating gene expression in plant seeds |
US7588931B2 (en) | 2004-11-04 | 2009-09-15 | E. I. Du Pont De Nemours And Company | High arachidonic acid producing strains of Yarrowia lipolytica |
US7198937B2 (en) * | 2004-11-04 | 2007-04-03 | E. I. Du Pont De Nemours And Company | Mortierella alpina diacylglycerol acyltransferase for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms |
EP1856264B1 (de) | 2005-02-26 | 2014-07-23 | BASF Plant Science GmbH | Expressionskassetten zur samenbevorzugten expression in pflanzen |
CA2606220A1 (en) * | 2005-04-19 | 2006-12-21 | Basf Plant Science Gmbh | Starchy-endosperm and/or germinating embryo-specific expression in mono-cotyledonous plants |
AU2006237346B2 (en) | 2005-04-20 | 2011-04-07 | Basf Plant Science Gmbh | Expression cassettes for seed-preferential expression in plants |
BRPI0614070A2 (pt) | 2005-05-10 | 2018-07-31 | Basf Plant Science Gmbh | cassetes de expressão, sequência de nucleotídeos isolada, seqüência sintética reguladora de transcrição, métodos para proporcionar uma seqüência sintética de nucleotídeos reguladora de transcrição, e um cassete de expressão, vetor, organismo não-humano ou célula hospedeira transgênico(a), e, célula de planta ou planta transgênica |
EP1906725A4 (de) * | 2005-05-20 | 2010-04-28 | Univ Washington State | Förderung der hydroxyfettsäureakkumulation in ölkulturpflanzen |
JP5242418B2 (ja) * | 2006-02-13 | 2013-07-24 | モンサント テクノロジー エルエルシー | 核酸構築体および変化した種子油組成の生成方法 |
CN101421406B (zh) | 2006-02-13 | 2016-08-31 | 孟山都技术有限公司 | 用于产生改变的种子油组成的核酸构建体和方法 |
US7888552B2 (en) | 2006-05-16 | 2011-02-15 | Monsanto Technology Llc | Use of non-agrobacterium bacterial species for plant transformation |
AU2007272316B2 (en) | 2006-07-14 | 2014-01-09 | Commonwealth Scientific And Industrial Research Organisation | Altering the fatty acid composition of rice |
EP2057177B1 (de) | 2006-08-04 | 2012-11-21 | Isis Pharmaceuticals, Inc. | Zusammensetzungen und ihre verwendung in bezug auf diacylglycerol-acyltransferase 1 |
WO2008063755A2 (en) * | 2006-10-03 | 2008-05-29 | Monsanto Technology Llc | Methods for hybrid corn seed production and compositions produced therefrom |
JP5124593B2 (ja) * | 2007-01-25 | 2013-01-23 | デュポン ニュートリション バイオサイエンシーズ エーピーエス | 形質転換バチルス・リケニフォルミス細胞からの脂質アシルトランスフェラーゼの製造 |
BRPI0808008B1 (pt) | 2007-02-16 | 2016-08-09 | Basf Plant Science Gmbh | molécula de ácido nucleico isolada, cassete de expressão, vetor de expressão, métodos para excisão de sequências alvo de uma planta, para produzir uma planta com rendimento aumentado, e/ou tolerância a estresse aumentada, e/ou qualidade nutritional aumentada, e/ou teor de óleo aumentado ou modificado de uma semente ou broto para a planta, e, uso da molécula de ácido nucleico |
US7838729B2 (en) | 2007-02-26 | 2010-11-23 | Monsanto Technology Llc | Chloroplast transit peptides for efficient targeting of DMO and uses thereof |
CN101675168A (zh) | 2007-03-09 | 2010-03-17 | 孟山都技术公司 | 用于转化的植物胚外植体的制备和用途 |
NZ554114A (en) * | 2007-04-23 | 2010-01-29 | Agres Ltd | Plants with an increased ratio of oleosin to TAG synthesising enzymes |
EP2147109B1 (de) | 2007-05-24 | 2014-03-19 | E. I. Du Pont de Nemours and Company | Dgat-gene aus yarrowia lipolytica für erhöhte samenfettproduktion sowie veränderte fettsäureprofile in sojabohnen |
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EP3115459A3 (de) | 2008-05-23 | 2017-04-26 | E. I. du Pont de Nemours and Company | Neuartige dgat-gene zur erhöhten samenfettproduktion sowie veränderte fettsäureprofile in ölsamenpflanzen |
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EP3737747A1 (de) | 2018-01-12 | 2020-11-18 | The Texas A&M University System | Erhöhung des ertrags von pflanzenbioprodukten |
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TW202300650A (zh) | 2021-03-26 | 2023-01-01 | 美商旗艦先鋒創新有限責任(Vii)公司 | 真核系統中環狀多核糖核苷酸的產生 |
TW202305130A (zh) | 2021-03-26 | 2023-02-01 | 美商旗艦先鋒創新有限責任(Vii)公司 | 原核系統中環狀多核糖核苷酸之產生 |
WO2023077118A1 (en) | 2021-11-01 | 2023-05-04 | Flagship Pioneering Innovations Vii, Llc | Polynucleotides for modifying organisms |
WO2023141540A2 (en) | 2022-01-20 | 2023-07-27 | Flagship Pioneering Innovations Vii, Llc | Polynucleotides for modifying organisms |
US20240093220A1 (en) | 2022-09-09 | 2024-03-21 | Friedrich Alexander Universität Erlangen-Nürnberg | Plant regulatory elements and uses thereof |
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JP2002504819A (ja) * | 1997-06-05 | 2002-02-12 | カルジーン エルエルシー | ジアシルグリセロールトランスフェラーゼタンパク質 |
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1999
- 1999-06-30 CA CA2331329A patent/CA2331329C/en not_active Expired - Fee Related
- 1999-06-30 WO PCT/US1999/015243 patent/WO2000001713A2/en active Application Filing
- 1999-06-30 BR BR9911800-9A patent/BR9911800A/pt not_active Application Discontinuation
- 1999-06-30 AT AT99932285T patent/ATE442435T1/de not_active IP Right Cessation
- 1999-06-30 EP EP99932285A patent/EP1098962B1/de not_active Expired - Lifetime
- 1999-06-30 JP JP2000558114A patent/JP4514952B2/ja not_active Expired - Lifetime
- 1999-06-30 DE DE69941390T patent/DE69941390D1/de not_active Expired - Lifetime
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2002
- 2002-04-15 US US10/121,857 patent/US6822141B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
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WO2000001713A3 (en) | 2000-11-16 |
EP1098962B1 (de) | 2009-09-09 |
ATE442435T1 (de) | 2009-09-15 |
US6822141B2 (en) | 2004-11-23 |
BR9911800A (pt) | 2001-02-28 |
JP2002519051A (ja) | 2002-07-02 |
US20030028923A1 (en) | 2003-02-06 |
JP4514952B2 (ja) | 2010-07-28 |
CA2331329C (en) | 2011-08-30 |
EP1098962A2 (de) | 2001-05-16 |
WO2000001713A2 (en) | 2000-01-13 |
CA2331329A1 (en) | 2000-01-13 |
WO2000001713A9 (en) | 2000-04-20 |
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