DE895546T1 - Verfahren zur isolierung bestimmter biologischer stoffe mittels magnetischer silika-partikel - Google Patents

Verfahren zur isolierung bestimmter biologischer stoffe mittels magnetischer silika-partikel

Info

Publication number
DE895546T1
DE895546T1 DE0895546T DE98908435T DE895546T1 DE 895546 T1 DE895546 T1 DE 895546T1 DE 0895546 T DE0895546 T DE 0895546T DE 98908435 T DE98908435 T DE 98908435T DE 895546 T1 DE895546 T1 DE 895546T1
Authority
DE
Germany
Prior art keywords
silica particles
specific biological
biological substances
magnetic silica
insulating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE0895546T
Other languages
English (en)
Inventor
Craig Smith
Charles York
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Promega Corp
Original Assignee
Promega Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25134438&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE895546(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Promega Corp filed Critical Promega Corp
Publication of DE895546T1 publication Critical patent/DE895546T1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/1013—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/832—Nanostructure having specified property, e.g. lattice-constant, thermal expansion coefficient
    • Y10S977/838—Magnetic property of nanomaterial
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915—Therapeutic or pharmaceutical composition
    • Y10S977/916—Gene therapy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/92—Detection of biochemical
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/924—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis using nanostructure as support of dna analysis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/932—Specified use of nanostructure for electronic or optoelectronic application
    • Y10S977/953—Detector using nanostructure
    • Y10S977/96—Of magnetic property
DE0895546T 1997-01-21 1998-01-21 Verfahren zur isolierung bestimmter biologischer stoffe mittels magnetischer silika-partikel Pending DE895546T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/785,097 US6027945A (en) 1997-01-21 1997-01-21 Methods of isolating biological target materials using silica magnetic particles
PCT/US1998/001149 WO1998031840A1 (en) 1997-01-21 1998-01-21 Methods of isolating biological target materials using silica magnetic particles

Publications (1)

Publication Number Publication Date
DE895546T1 true DE895546T1 (de) 2002-10-17

Family

ID=25134438

Family Applications (3)

Application Number Title Priority Date Filing Date
DE69817484T Expired - Lifetime DE69817484T2 (de) 1997-01-21 1998-01-21 Verfahren zur isolierung bestimmter biologischer stoffe mittels magnetischer silika-partikel
DE69841555T Expired - Lifetime DE69841555D1 (de) 1997-01-21 1998-01-21 Verfahren zur Isolierung bestimmter biologischer Stoffe mittels magnetischer Silika-Partikel
DE0895546T Pending DE895546T1 (de) 1997-01-21 1998-01-21 Verfahren zur isolierung bestimmter biologischer stoffe mittels magnetischer silika-partikel

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE69817484T Expired - Lifetime DE69817484T2 (de) 1997-01-21 1998-01-21 Verfahren zur isolierung bestimmter biologischer stoffe mittels magnetischer silika-partikel
DE69841555T Expired - Lifetime DE69841555D1 (de) 1997-01-21 1998-01-21 Verfahren zur Isolierung bestimmter biologischer Stoffe mittels magnetischer Silika-Partikel

Country Status (9)

Country Link
US (5) US6027945A (de)
EP (2) EP0895546B1 (de)
JP (1) JP3253638B2 (de)
AU (1) AU732756B2 (de)
BR (1) BR9805897A (de)
CA (1) CA2249393A1 (de)
DE (3) DE69817484T2 (de)
DK (1) DK1367137T3 (de)
WO (1) WO1998031840A1 (de)

Families Citing this family (260)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9425138D0 (en) 1994-12-12 1995-02-08 Dynal As Isolation of nucleic acid
KR100463475B1 (ko) 1995-06-08 2005-06-22 로셰 디아그노스틱스 게엠베하 자기성피그먼트
DE19520398B4 (de) * 1995-06-08 2009-04-16 Roche Diagnostics Gmbh Magnetisches Pigment
JP2965131B2 (ja) * 1995-07-07 1999-10-18 東洋紡績株式会社 核酸結合用磁性担体およびそれを用いる核酸単離方法
CA2255599C (en) 1996-04-25 2006-09-05 Bioarray Solutions, Llc Light-controlled electrokinetic assembly of particles near surfaces
DE69810080T2 (de) 1997-01-21 2003-10-09 Grace W R & Co Siliciumdioxidadsorbent auf magnetischem träger
US20050287583A1 (en) * 1997-01-21 2005-12-29 Promega Corporation Methods and kits for isolating biological target materials using silica magnetic particles
US6027945A (en) * 1997-01-21 2000-02-22 Promega Corporation Methods of isolating biological target materials using silica magnetic particles
WO1998050567A1 (en) * 1997-05-02 1998-11-12 Abbott Laboratories Reagents and methods useful for detecting diseases of the prostate
DE19743518A1 (de) * 1997-10-01 1999-04-15 Roche Diagnostics Gmbh Automatisierbare universell anwendbare Probenvorbereitungsmethode
US7569342B2 (en) * 1997-12-10 2009-08-04 Sierra Molecular Corp. Removal of molecular assay interferences
US20080064108A1 (en) * 1997-12-10 2008-03-13 Tony Baker Urine Preservation System
DE69815282T2 (de) * 1997-12-25 2004-05-06 Tosoh Corp., Shinnanyo Magnetischer Träger, seine Herstellung, und Verfahren zum Extrahieren von Nukleinsäuren
US7078224B1 (en) 1999-05-14 2006-07-18 Promega Corporation Cell concentration and lysate clearance using paramagnetic particles
US6534262B1 (en) 1998-05-14 2003-03-18 Whitehead Institute For Biomedical Research Solid phase technique for selectively isolating nucleic acids
EP0969090A1 (de) * 1998-05-27 2000-01-05 QIAGEN GmbH Schnelles und einfaches Verfahren zur Isolierung von zirkulären Nucleinsäuren
US6368866B1 (en) 1998-08-03 2002-04-09 Reference Diagnostics, Inc. Rapid separation assay for total iron binding capacity
US6703228B1 (en) * 1998-09-25 2004-03-09 Massachusetts Institute Of Technology Methods and products related to genotyping and DNA analysis
ATE316152T1 (de) * 1998-10-27 2006-02-15 Affymetrix Inc Komplexitätsmanagement und analyse genomischer dna
US5973138A (en) * 1998-10-30 1999-10-26 Becton Dickinson And Company Method for purification and manipulation of nucleic acids using paramagnetic particles
DE59906909D1 (de) * 1998-11-30 2003-10-09 Roche Diagnostics Gmbh Magnetische partikel zur reinigung von nukleinsäuren
WO2000042410A1 (en) * 1999-01-18 2000-07-20 Precision System Science Co., Ltd. Concentration device using magnetic particles and method therefor
FI990082A0 (fi) * 1999-01-18 1999-01-18 Labsystems Oy Puhdistusprosessi magneettipartikkeleita käyttäen
AU2731700A (en) * 1999-01-20 2000-08-07 Reference Diagnostics, Inc. Magnetically responsive gel particle
ATE530648T1 (de) * 1999-05-14 2011-11-15 Promega Corp Zell konzentration und lysat klärung mittels paramagnetischen partikeln
US6310199B1 (en) 1999-05-14 2001-10-30 Promega Corporation pH dependent ion exchange matrix and method of use in the isolation of nucleic acids
EP1621618B1 (de) 1999-05-14 2011-10-26 Promega Corporation Zell Konzentration und lysat Klärung mittels paramagnetischen Partikeln
US6270970B1 (en) * 1999-05-14 2001-08-07 Promega Corporation Mixed-bed solid phase and its use in the isolation of nucleic acids
ATE320443T1 (de) * 1999-07-15 2006-04-15 Qiagen Gmbh Verfahren zur trennung von teilchenförmigen substraten aus einer lösung indem man den teilchenverlust minimiert
DE19937607A1 (de) * 1999-08-09 2001-02-15 Bilatec Ges Zur Entwicklung Bi Reagenzienkit zur Isolierung von Nukleinsäuren
EP1510578A3 (de) * 1999-08-20 2005-03-16 Promega Corporation Simultane Isolierung und Quantifizierung von DNA
CA2379503A1 (en) * 1999-08-20 2001-03-01 Promega Corporation Simultaneous isolation and quantitation of dna
US6503761B1 (en) * 1999-10-19 2003-01-07 Kimberly-Clark Worldwide, Inc. Selective removal of contaminants from a surface using articles having magnets
US6841393B2 (en) 1999-10-19 2005-01-11 Kimberly-Clark Worldwide, Inc. Selective removal of contaminants from a surface using colored particles and articles having magnets
US6958225B2 (en) 1999-10-27 2005-10-25 Affymetrix, Inc. Complexity management of genomic DNA
WO2001037291A1 (en) * 1999-11-17 2001-05-25 Roche Diagnostics Gmbh Magnetic glass particles, method for their preparation and uses thereof
US6936414B2 (en) * 1999-12-22 2005-08-30 Abbott Laboratories Nucleic acid isolation method and kit
AU6380001A (en) * 2000-03-24 2001-10-03 Qiagen Gmbh Porous ferro- or ferrimagnetic glass particles for isolating molecules
US6672458B2 (en) * 2000-05-19 2004-01-06 Becton, Dickinson And Company System and method for manipulating magnetically responsive particles fluid samples to collect DNA or RNA from a sample
WO2001089705A2 (en) * 2000-05-19 2001-11-29 Becton Dickinson And Company System and method for manipulating magnetically responsive particles in fluid samples to collect dna or rna from a sample
GB0013658D0 (en) * 2000-06-05 2000-07-26 Dynal Asa Nucleic acid isolation
US7892854B2 (en) * 2000-06-21 2011-02-22 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
WO2002000342A2 (en) * 2000-06-23 2002-01-03 Irm, Llc Method and apparatus for performing an assay
EP1978110B1 (de) * 2000-09-06 2010-05-26 Transnetyx, Inc. Computer-basiertes Verfahren und System zum Screenen von genomischer DNS
US20050272085A1 (en) * 2000-09-06 2005-12-08 Hodge Timothy A Methods for forensic and congenic screening
US20050239125A1 (en) * 2000-09-06 2005-10-27 Hodge Timothy A Methods for genotype screening
US7494817B2 (en) * 2000-09-06 2009-02-24 Transnet Yx, Inc. Methods for genotype screening using magnetic particles
KR20020065509A (ko) * 2000-09-06 2002-08-13 티모시 에이. 호지 유전자이식 및 표적 돌연변이유발 스크리닝을 위한시스템, 방법 및 장치
WO2002020842A1 (en) * 2000-09-06 2002-03-14 Transnetyx, Inc. System, method and apparatus for transgenic and targeted mutagenesis screening
US20050266494A1 (en) * 2000-09-06 2005-12-01 Hodge Timothy A System and method for computer network ordering of biological testing
US20030087286A1 (en) * 2000-09-06 2003-05-08 Hodge Timothy A. Isolation of eukaryotic genomic DNA using magnetically responsive solid functionalized particles
US20030082605A1 (en) * 2000-09-06 2003-05-01 Hodge Timothy A. Genomic DNA detection method and system thereof
US20030207289A1 (en) * 2001-09-04 2003-11-06 Hodge Timothy A. Detection of genetic sequences using a bipartite probe
ATE342355T1 (de) * 2000-11-13 2006-11-15 Promega Corp Lysat-klärung und nukleinsäureisolierung mit silanisierten silicamatrizes
WO2002044414A2 (en) * 2000-11-28 2002-06-06 Promega Corporation Purification of dna sequencing reactions using silica magnetic particles
US6607667B2 (en) * 2000-11-28 2003-08-19 W. R. Grace & Co.-Conn. Method for adsorbing substances using silica adsorbent on magnetic substrate
US6794141B2 (en) * 2000-12-22 2004-09-21 Arcturus Bioscience, Inc. Nucleic acid amplification
AU2002220449B2 (en) * 2001-01-19 2006-08-10 Drm, Dr. Muller Ag Method for treating biomass for producing cell lysate containing plasmid DNA
JP4399164B2 (ja) 2001-02-16 2010-01-13 プロメガ・コーポレーション 核酸の磁気単離および精製の方法
US6855499B1 (en) 2001-02-16 2005-02-15 Cortex Biochem, Inc. Magnetic isolation and purification of nucleic acids
US20030022203A1 (en) * 2001-04-23 2003-01-30 Rajan Kumar Cellular Arrays
US6656587B2 (en) 2001-05-02 2003-12-02 Phillips Plastics Corporation Composite particles
US6849186B2 (en) * 2001-05-02 2005-02-01 Phillips Plastic Corporation Composite particles
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
US7217513B2 (en) * 2001-07-10 2007-05-15 Massachusetts Institute Of Technology Apparatus and method for isolating a nucleic acid from a sample
US7169578B2 (en) * 2001-07-27 2007-01-30 Surface Logix, Inc. Cell isolation and screening device and method of using same
US7285412B2 (en) * 2001-07-27 2007-10-23 Surface Logix Inc. Device for magnetic immobilization of cells
US7169577B2 (en) * 2001-07-27 2007-01-30 Surface Logix, Inc. Cell isolation and screening device and method of using same
US20030040129A1 (en) * 2001-08-20 2003-02-27 Shah Haresh P. Binding assays using magnetically immobilized arrays
US20060014186A1 (en) * 2001-09-04 2006-01-19 Hodge Timothy A Methods for genotype screening of a strain disposed on an adsorbent carrier
US20040137449A1 (en) * 2001-10-05 2004-07-15 Nargessi R D Magnetic isolation and purification of nucleic acids
KR20040068122A (ko) 2001-10-15 2004-07-30 바이오어레이 솔루션스 리미티드 공동 검색과 효소-매개된 탐지에 의한 다형성 좌위의 다중분석
AU2002333673B2 (en) 2001-11-06 2008-08-14 Promega Corporation Isolation and purification of nucleic acids
JP2005538929A (ja) 2002-01-16 2005-12-22 ダイナル バイオテック エイエスエイ 単一サンプルからの核酸及びタンパク質の単離方法
WO2003068788A1 (en) * 2002-02-13 2003-08-21 Medimolecular Pty. Ltd. Method of isolating nucleic acids from stool samples
AU2003220249A1 (en) * 2002-03-15 2003-09-29 Arcturus Bioscience, Inc. Improved nucleic acid amplification
US7214427B2 (en) * 2002-03-21 2007-05-08 Aviva Biosciences Corporation Composite beads comprising magnetizable substance and electro-conductive substance
GB0207975D0 (en) * 2002-04-05 2002-05-15 Genovision As Isolating nucleic acid
GB0210766D0 (en) * 2002-05-10 2002-06-19 Genovision As Isolating nucleic acid
US20040126902A1 (en) * 2002-06-27 2004-07-01 Toyo Boseki Kabushiki Kaisha Magnetic carrier for biological substance, production method thereof and isolation method of biological substance using same
GB0215185D0 (en) 2002-07-01 2002-08-07 Genovision As Binding a target substance
WO2004005553A1 (en) * 2002-07-10 2004-01-15 Massachusetts Institute Of Technology Apparatus and method for isolating a nucleic acid from a sample
EP1527345A2 (de) * 2002-07-29 2005-05-04 Axxima Pharmaceuticals AG Verfahren zur abtrennung von atp-bindenden proteinen durch immobilisierte inhibitoren
US7183104B1 (en) 2002-08-23 2007-02-27 Duane Morris Llp Separator and particle detection system
US7176036B2 (en) * 2002-09-20 2007-02-13 Arrowhead Center, Inc. Electroactive microspheres and methods
US7526114B2 (en) 2002-11-15 2009-04-28 Bioarray Solutions Ltd. Analysis, secure access to, and transmission of array images
GB0229287D0 (en) * 2002-12-16 2003-01-22 Dna Res Innovations Ltd Polyfunctional reagents
US7601491B2 (en) * 2003-02-06 2009-10-13 Becton, Dickinson And Company Pretreatment method for extraction of nucleic acid from biological samples and kits therefor
US20040157219A1 (en) * 2003-02-06 2004-08-12 Jianrong Lou Chemical treatment of biological samples for nucleic acid extraction and kits therefor
JP2004000922A (ja) * 2003-03-26 2004-01-08 Toyobo Co Ltd 核酸またはタンパク質抽出用シリカ粒子組成物
JP4836795B2 (ja) * 2003-05-19 2011-12-14 ブランデイズ ユニバーシティー 核酸プロセシング方法、キット、及び装置
JP4612789B2 (ja) * 2003-05-29 2011-01-12 キヤノン株式会社 Ｄｎａハイブリッド及びｄｎａハイブリッドを用いた環境浄化システム
WO2004108925A1 (en) * 2003-06-04 2004-12-16 Qiagen As Method for sequentially isolating dna and rna from the same nucleic acid-containing sample
US20050042660A1 (en) * 2003-07-31 2005-02-24 Hall Gerald Edward Devices and methods for isolating RNA
GB0319671D0 (en) * 2003-08-21 2003-09-24 Secr Defence Apparatus for processing a fluid sample
EP1510577A1 (de) * 2003-08-29 2005-03-02 Qiagen GmbH Verfahren zur Magnetische Kügelchem Isolierung von Nukleinsäuren
WO2005029705A2 (en) * 2003-09-18 2005-03-31 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
CA2539824C (en) * 2003-09-22 2015-02-03 Xinwen Wang Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
US20050089916A1 (en) * 2003-10-28 2005-04-28 Xiongwu Xia Allele assignment and probe selection in multiplexed assays of polymorphic targets
AU2004286252A1 (en) 2003-10-28 2005-05-12 Bioarray Solutions Ltd. Optimization of gene expression analysis using immobilized capture probes
WO2005045060A2 (en) 2003-10-29 2005-05-19 Bioarray Solutions, Ltd. Multiplexed nucleic acid analysis by fragmentation of double-stranded dna
US20050106576A1 (en) * 2003-11-17 2005-05-19 Hashem Akhavan-Tafti Methods of using cleavable solid phases for isolating nucleic acids
US20050136477A1 (en) * 2003-11-17 2005-06-23 Hashem Akhavan-Tafti Methods for isolating nucleic acids from biological and cellular materials
US20050106589A1 (en) * 2003-11-17 2005-05-19 Hashem Akhavan-Tafti Compositions and methods for releasing nucleic acids from solid phase binding materials
US20050106577A1 (en) * 2003-11-17 2005-05-19 Hashem Akhavan-Tafti Cleavable solid phases for isolating nucleic acids
US20050106602A1 (en) * 2003-11-17 2005-05-19 Hashem Akhavan-Tafti Simplified methods for isolating nucleic acids from cellular materials
DE10358137A1 (de) * 2003-12-12 2005-07-07 Merck Patent Gmbh Verfahren und Kit zur Isolierung von RNA
KR20060129340A (ko) * 2003-12-30 2006-12-15 시그마-알드리치컴퍼니 효소 소화에 의한 핵산의 신속한 제조
WO2005079984A1 (en) * 2004-02-18 2005-09-01 Applera Corporation Polyelectrolyte-coated size-exclusion ion-exchange particles
US8426126B2 (en) 2004-03-18 2013-04-23 Applied Biosystems, Llc Modified surfaces as solid supports for nucleic acid purification
US20050239091A1 (en) * 2004-04-23 2005-10-27 Collis Matthew P Extraction of nucleic acids using small diameter magnetically-responsive particles
US20050236299A1 (en) * 2004-04-27 2005-10-27 Mark Weber Folded material containment packages and related methods of packaging folded material products
NL1026271C2 (nl) * 2004-05-26 2005-11-30 Keygene Nv Werkwijze en inrichting voor het isoleren van nucleïnezuur uit nucleïnezuur bevattend materiaal.
WO2006004611A2 (en) * 2004-06-25 2006-01-12 Invitrogen Corporation Separation of nucleic acid
JP4476050B2 (ja) * 2004-06-30 2010-06-09 株式会社ニデック 視野計
US7363170B2 (en) * 2004-07-09 2008-04-22 Bio Array Solutions Ltd. Transfusion registry network providing real-time interaction between users and providers of genetically characterized blood products
EP1776458A2 (de) 2004-07-30 2007-04-25 Agencourt Bioscience Corporation Verfahren zur isolierung von nukleinsäuren mit hilfe von festphasenträgern mit multifunktionalen gruppen
JP4798971B2 (ja) * 2004-07-30 2011-10-19 キヤノン株式会社 磁性粒子集合体およびそれを用いた標的核酸の抽出装置および抽出方法
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
ES2371764T3 (es) 2004-08-03 2012-01-09 Novartis Vaccines And Diagnostics, Inc. Procedimiento de obtención de ácidos nucleicos mediante lisis de muestras microbianas.
WO2006017428A2 (en) * 2004-08-03 2006-02-16 Becton, Dickinson And Company Use of magnetic material to direct isolation of compounds and fractionation of multipart samples
WO2006017427A1 (en) * 2004-08-03 2006-02-16 Becton, Dickinson And Company Use of magnetic material to fractionate samples
EP1623996A1 (de) * 2004-08-06 2006-02-08 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Verbessertes Verfahren zur Auswahl eines Proteins von einer Bibliothek
US20060099605A1 (en) * 2004-11-11 2006-05-11 Hall Gerald E Jr Devices and methods for isolating RNA
US7320891B2 (en) * 2004-09-10 2008-01-22 Promega Corporation Methods and kits for isolating sperm cells
US7166680B2 (en) * 2004-10-06 2007-01-23 Advanced Cardiovascular Systems, Inc. Blends of poly(ester amide) polymers
EP1650297B1 (de) * 2004-10-19 2011-04-13 Samsung Electronics Co., Ltd. Verfahren und Apparatur zur schnellen Zerstörung von Zellen und Viren durch die Verwendung von mikro magnet Kügelchen und Laser
DE102005002343A1 (de) 2005-01-18 2006-07-27 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zur spezifischen oder unspezifischen Separation von Zellen und/oder Viren aus flüssigen Medien und dessen Verwendung
US7964380B2 (en) * 2005-01-21 2011-06-21 Argylia Technologies Nanoparticles for manipulation of biopolymers and methods of thereof
US20060166223A1 (en) * 2005-01-26 2006-07-27 Reed Michael W DNA purification and analysis on nanoengineered surfaces
EP1690938A1 (de) * 2005-02-11 2006-08-16 Qiagen GmbH Verfahren zur Isolierung von Nukleinsäuren, wobei die Nukleinsäuren bei erhöhter Temperatur an einer Matrix immobilisiert werden
ITRM20050067A1 (it) 2005-02-17 2006-08-18 Istituto Naz Per Le Malattie I Metodo per la rivelazione di acidi nucleici virali o di origine virale nelle urine.
ITRM20050068A1 (it) * 2005-02-17 2006-08-18 Istituto Naz Per Le Malattie I Metodo per la rivelazione di acidi nucleici di agenti patogeni batterici o di parassiti nelle urine.
US7914982B2 (en) * 2005-02-17 2011-03-29 Trovagene, Inc. Methods for detecting pathogen specific nucleic acids in urine
US20060223071A1 (en) * 2005-04-01 2006-10-05 Wisniewski Michele E Methods, compositions, and kits for detecting nucleic acids in a single vessel
US8632970B2 (en) * 2005-05-09 2014-01-21 Affymetrix, Inc. Multiplex capture of nucleic acids
US8628918B2 (en) * 2005-05-09 2014-01-14 Affymetrix, Inc. Multiplex capture of nucleic acids
ATE502120T1 (de) 2005-05-12 2011-04-15 Affymetrix Inc Multiplex-assays für verzweigtkettige dna
US20060270843A1 (en) * 2005-05-26 2006-11-30 Hall Gerald E Jr Methods for isolation of nucleic acids
US20060269929A1 (en) * 2005-05-26 2006-11-30 Hall Gerald E Jr Methods and kits for DNA purification on polymeric membranes at low ionic strength
US8486629B2 (en) 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
ES2565670T3 (es) * 2005-06-20 2016-04-06 Advanced Cell Diagnostics, Inc. Métodos de detección de ácidos nucleicos en células individuales y de identificación de células raras en grandes poblaciones de células heterogéneas
EP1907585A4 (de) * 2005-07-01 2010-04-07 Promega Corp Netzwerk aus auftriebspartikeln für die biomolekülreinigung und verwendung von auftriebspartikeln oder dem netzwerk aus auftriebspartikeln zur biomolekülreinigung
US20070072195A1 (en) * 2005-09-29 2007-03-29 Constantine Haralambopoulos Bio-commemorative article incorporating amplified genetic material
US7927798B2 (en) * 2005-10-05 2011-04-19 Panomics, Inc. Detection of nucleic acids from whole blood
US7727473B2 (en) 2005-10-19 2010-06-01 Progentech Limited Cassette for sample preparation
US7754148B2 (en) 2006-12-27 2010-07-13 Progentech Limited Instrument for cassette for sample preparation
US20070092403A1 (en) * 2005-10-21 2007-04-26 Alan Wirbisky Compact apparatus, compositions and methods for purifying nucleic acids
US8030034B2 (en) * 2005-12-09 2011-10-04 Promega Corporation Nucleic acid purification with a binding matrix
WO2007094506A1 (ja) * 2006-02-15 2007-08-23 Tosoh Corporation 生物材料からの核酸抽出法
US20070254284A1 (en) * 2006-05-01 2007-11-01 Biwei Zhao A nucleic acid detection method
US7608399B2 (en) * 2006-06-26 2009-10-27 Blood Cell Storage, Inc. Device and method for extraction and analysis of nucleic acids from biological samples
US8163535B2 (en) * 2006-06-26 2012-04-24 Blood Cell Storage, Inc. Devices and processes for nucleic acid extraction
EP2054501A4 (de) * 2006-10-06 2010-11-03 Promega Corp Verfahren und kits zur isolation von zellen
EP1911844A1 (de) 2006-10-10 2008-04-16 Qiagen GmbH Verfahren und Zusammenstellung zur Isolierung von Nukleinsäure
US8895267B2 (en) 2006-11-03 2014-11-25 Siemens Healthcare Diagnostics Inc. Random access system and method for polymerase chain reaction testing
EP2094846B8 (de) * 2006-12-13 2013-10-16 Roche Diagnostics GmbH Verwendung von tde zur isolation von nukleinsäuren
WO2008071385A2 (en) * 2006-12-13 2008-06-19 Roche Diagnostics Gmbh Use of acetals for the isolation of nucleic acids
CN101627065B (zh) * 2006-12-21 2012-05-23 茵维特罗根戴纳股份公司 颗粒和其在分离核酸的方法或分离磷蛋白的方法中的应用
US8993292B2 (en) * 2007-01-16 2015-03-31 Applied Biosystems Llc Methods and systems for differential extraction
US7960180B2 (en) * 2007-02-20 2011-06-14 University Of Notre Dame Du Lac Methods and apparatus to capture and release microbe particles using amino-functionalized silica
EP2140001A2 (de) * 2007-04-25 2010-01-06 3M Innovative Properties Company Verfahren zur amplifikation von nukleinsäuren
DK2171098T3 (en) * 2007-06-29 2018-05-22 Becton Dickinson Co PROCEDURES FOR EXTRACTION AND CLEANING COMPONENTS IN BIOLOGICAL SAMPLES
US7868145B2 (en) * 2007-07-11 2011-01-11 Industrial Technology Research Institute Magnetic particles containing a copolymer core, magnetic layer and silicon layer
US8969044B2 (en) 2007-07-23 2015-03-03 Life Technologies Corporation Method for recovering sperm nucleic acid from a forensic sample
DK2195450T4 (en) * 2007-08-22 2016-10-24 Trovagene Inc Methods of using miRNA FOR DETECTION IN VIVO cell death
CN101363045B (zh) * 2007-09-10 2012-10-17 厦门致善生物科技有限公司 一种用超微磁颗粒分离纯化生物靶物质的方法
US9388457B2 (en) 2007-09-14 2016-07-12 Affymetrix, Inc. Locus specific amplification using array probes
US8357296B2 (en) * 2007-09-24 2013-01-22 Emd Millipore Corporation Centrifugal filter
WO2009068583A2 (en) * 2007-11-26 2009-06-04 Atonomics A/S Separation and detection device with means for optimization of the capillary drag force
US20110165565A1 (en) 2008-01-03 2011-07-07 The Johns Hopkins University Compositions and methods for polynucleotide extraction and methylation detection
KR101053023B1 (ko) * 2008-02-14 2011-08-01 (주)바이오니아 구형 실리카 자성입자 및 이의 제조방법
US9074244B2 (en) * 2008-03-11 2015-07-07 Affymetrix, Inc. Array-based translocation and rearrangement assays
AU2009223122B2 (en) 2008-03-12 2014-12-11 University Of Virginia Patent Foundation Detection of polymeric analytes
US20120149587A1 (en) * 2008-03-12 2012-06-14 University Of Virginia Patent Foundation Method for detecting nucleated cells
DE102008029356A1 (de) * 2008-06-20 2009-12-24 Siemens Healthcare Diagnostics Gmbh Verfahren zur Aufreinigung von Nukleinsäuren, insbesondere aus fixiertem Gewebe
EP2147981A1 (de) * 2008-07-25 2010-01-27 Biotype AG Kit und Verfahren zur Auswertung der Detektionseigenschaften bei Verstärkungsreaktionen
US20100062518A1 (en) * 2008-09-09 2010-03-11 Sukanta Banerjee Concentrating White Blood Cells for DNA Extraction from a Leukodepleted Blood Sample
WO2010040108A2 (en) * 2008-10-03 2010-04-08 Board Of Regents, The University Of Texas System Method for measuring carbon nanotube taken-up by a plurality of living cells
CA2742598A1 (en) * 2008-11-04 2010-05-14 Blood Cell Storage, Inc. Nucleic acid extraction on curved glass surfaces
US8846878B1 (en) 2009-01-23 2014-09-30 Cubrc Corporation Method and device for isolating a protein sample
WO2010088517A1 (en) * 2009-01-30 2010-08-05 The U.S.A., As Represented By The Secretary, Department Of Health And Human Services Methods and systems for purifying transferring and/or manipulating nucleic acids
DE102009001864A1 (de) * 2009-03-25 2010-09-30 Qiagen Gmbh Überschichtung zur Partikelabtrennung
DE102009022512A1 (de) * 2009-05-25 2010-12-02 Qiagen Gmbh Verfahren zur Reaktivierung von Silikaoberflächen zur Isolierung von Nukleinsäuren
US8039613B2 (en) * 2009-08-28 2011-10-18 Promega Corporation Methods of purifying a nucleic acid and formulation and kit for use in performing such methods
US8222397B2 (en) * 2009-08-28 2012-07-17 Promega Corporation Methods of optimal purification of nucleic acids and kit for use in performing such methods
US8697435B2 (en) * 2009-08-31 2014-04-15 Mbio Diagnostics, Inc. Integrated sample preparation and analyte detection
US11096345B2 (en) 2009-09-01 2021-08-24 Basf Se Method for treating post-emergent rice
TW201113376A (en) 2009-09-01 2011-04-16 Basf Agrochemical Products Bv Herbicide-tolerant plants
TWI407994B (zh) 2009-10-22 2013-09-11 Ind Tech Res Inst 分離核酸的方法、試劑及套組
EP2517015A1 (de) * 2009-12-23 2012-10-31 Koninklijke Philips Electronics N.V. Analytmessvorrichtung und verfahren
EP2345719A1 (de) 2010-01-18 2011-07-20 Qiagen GmbH Verfahren zur Isolierung kleiner RNA
WO2011106384A1 (en) 2010-02-23 2011-09-01 Genturadx, Inc. Apparatus and methods for integrated sample preparation, reaction and detection
US20110223588A1 (en) * 2010-03-09 2011-09-15 Biosample Llc Solid Phase Nucleic Acid Extraction From Small Sample Volumes, and Release of Controlled Quantities
EP2407540A1 (de) 2010-07-15 2012-01-18 Qiagen GmbH Verfahren zur Reinigung von Nukleinsäure
DE102010036111B4 (de) 2010-09-01 2013-08-29 Bundesrepublik Deutschland (Bundesamt für Ausrüstung, Informationstechnik und Nutzung der Bundeswehr) Vorbehandlungsverfahren zur Isolierung und Aufkonzentrierung von Nukleinsäuren aus einer Umweltprobe
US8658361B2 (en) 2010-10-21 2014-02-25 Advanced Cell Diagnostics, Inc. Ultra sensitive method for in situ detection of nucleic acids
EP3239296A1 (de) 2010-11-30 2017-11-01 Life Technologies Corporation Alkylenglykole sowie polymere und copolymere daraus zur direkten isolierung von nukleinsäuren aus eingebetteten proben
MY169304A (en) 2010-12-16 2019-03-21 Basf Agro Bv Plants having increased tolerance to herbicides
EP2465934A1 (de) 2010-12-20 2012-06-20 Steffen Mergemeier Extraktion von Nukleinsäuren
US9051563B2 (en) 2011-01-14 2015-06-09 Zymo Research Corporation Nucleic acid purification
WO2012151473A2 (en) 2011-05-04 2012-11-08 Luminex Corporation Apparatus and methods for integrated sample preparation, reaction and detection
WO2012159063A2 (en) 2011-05-19 2012-11-22 Blood Cell Strorage, Inc. Gravity flow fluidic device for nucleic acid extraction
US9304070B2 (en) 2011-07-13 2016-04-05 Emd Millipore Corporation All-in-one sample preparation device and method
DE102011054474B4 (de) 2011-07-20 2014-02-13 Stratec Biomedical Ag System zur Stabilisierung, Aufbewahrung und Lagerung einer Nukleinsäure
US9695465B2 (en) 2011-08-12 2017-07-04 Qiagen Gmbh Method for isolating nucleic acids
ES2675584T3 (es) 2012-01-30 2018-07-11 Exact Sciences Development Company, Llc Modificación de ADN en perlas magnéticas
EP2634254A1 (de) 2012-02-29 2013-09-04 QIAGEN GmbH Verfahren zur Isolierung von Nukleinsäuren aus Nahrungsmittelproben
US10041087B2 (en) 2012-06-19 2018-08-07 BASF Agro B.V. Plants having increased tolerance to herbicides
AR091489A1 (es) 2012-06-19 2015-02-11 Basf Se Plantas que tienen una mayor tolerancia a herbicidas inhibidores de la protoporfirinogeno oxidasa (ppo)
CN104540594B (zh) * 2012-06-25 2019-07-02 通用医疗公司 使用高梯度磁场对粒子进行分类
EP2770056B1 (de) 2012-07-18 2017-05-31 Zymo Research Corporation Nukleinsäurereinigung
FR2994184B1 (fr) 2012-08-02 2017-12-08 Biomerieux Sa Procedes de fonctionalisation et reactifs utilises dans de tels procedes utilisant un anhydride aza-isatoique ou un de ses derives, molecules biologiques ainsi traitees et kits
US10233508B2 (en) 2012-08-21 2019-03-19 Qiagen Gmbh Virus particle stabilisation and method for isolating viral nucleic acids
US20150225712A1 (en) 2012-08-21 2015-08-13 Qiagen Gmbh Method for isolating nucleic acids from a formaldehyde releaser stabilized sample
AU2013310861B2 (en) 2012-09-03 2019-02-14 Qiagen Gmbh Method for isolating RNA including small RNA with high yield
CA2885263C (en) 2012-09-17 2021-11-16 W. R. Grace & Co.-Conn. Chromatography media and devices
GB201217405D0 (en) 2012-09-28 2012-11-14 Fermentas Uab Protein removal agent
WO2014122288A1 (en) 2013-02-08 2014-08-14 Qiagen Gmbh Method for separating dna by size
EP2962107A1 (de) 2013-03-01 2016-01-06 Spinomix S.A. Auf magnetischen partikeln basierte trennung und testverfahren
EP2971169A4 (de) * 2013-03-13 2016-10-26 Abbott Molecular Inc Systeme und verfahren zur isolierung von nukleinsäuren
US9670479B2 (en) 2013-03-15 2017-06-06 F Cubed, LLC Sample preparation device and methods of use
JP5802237B2 (ja) * 2013-04-18 2015-10-28 三洋化成工業株式会社 磁性粒子及びその製造方法
BR112016002835A2 (pt) 2013-08-12 2017-09-19 Basf Agro Bv Plantas, semente, células vegetais, produtos vegetais, prole ou planta descendente derivada de uma planta, método de controle de ervas, método de produção de planta, método de produção de plantas de prole, método de produção de produtos vegetais, método de cultivo da planta, combinação útil para controle de ervas, processos de preparação da combinação útil para controle de ervas e uso da combinação
EA201690374A1 (ru) 2013-08-12 2016-07-29 Басф Агро Б.В. Растения с повышенной устойчивостью к гербицидам
DE202014002379U1 (de) 2014-03-15 2014-08-19 Ruprecht-Karls-Universität Heidelberg DNA Stabilisierungssystem
WO2015150465A2 (en) 2014-04-03 2015-10-08 Basf Se Plants having increased tolerance to herbicides
WO2015168383A1 (en) 2014-05-02 2015-11-05 W. R. Grace & Co.-Conn. Functionalized support material and methods of making and using functionalized support material
WO2015199423A1 (ko) * 2014-06-24 2015-12-30 (주)바이오니아 자성 입자를 이용한 핵산 분리 방법
WO2016057891A1 (en) 2014-10-09 2016-04-14 Promega Corporation Method of isolating nucleic acid
CN107112105A (zh) 2014-10-23 2017-08-29 康宁股份有限公司 聚合物包封的磁性纳米颗粒
JP6773402B2 (ja) * 2014-11-04 2020-10-21 三洋化成工業株式会社 磁性シリカ粒子を用いた対象物質の分離方法
EP3059312A1 (de) 2015-02-20 2016-08-24 QIAGEN GmbH Nukleinsäureextraktionsverfahren
US9422596B1 (en) 2015-04-27 2016-08-23 Norgen Biotek Corp. Methods and columns for nucleic acid purification
KR101646610B1 (ko) 2015-05-28 2016-08-09 (주)바이오니아 생체 물질 정제용 고활성 실리카 자성나노입자 및 이의 제조 방법
US10794859B2 (en) 2015-06-01 2020-10-06 Qiagen Gmbh Electrophoresis assisted method and device for purifying a charged target molecule from a sample
WO2016193282A1 (en) 2015-06-01 2016-12-08 Qiagen Gmbh Electrophoresis assisted method for purifying a target nucleic acid using a delayed elution approach
EP3303630B1 (de) 2015-06-05 2022-01-05 Qiagen GmbH Verfahren zum trennen von dns anhand der grösse
SG10201911134QA (en) 2015-06-05 2020-01-30 Grace W R & Co Adsorbent bioprocessing clarification agents and methods of making and using the same
CN108026570A (zh) * 2015-09-11 2018-05-11 康宁股份有限公司 从血液样品中纯化核酸的组合物和方法
CN108368543B (zh) 2015-10-12 2023-06-13 领先细胞医疗诊断有限公司 高噪声样品中原位检测核苷酸变体及相关的组合物和方法
EP4166660A1 (de) 2016-04-29 2023-04-19 BASF Plant Science Company GmbH Verbesserte verfahren zur modifizierung von zielnukleinsäuren
TR201606310A2 (tr) 2016-05-12 2017-11-21 Akdeniz Ueniversitesi Genomik dna izolasyon yöntemi ve kiti.
CA3024770A1 (en) 2016-05-20 2017-11-23 BASF Agro B.V. Dual transit peptides for targeting polypeptides
CA3029178C (en) 2016-06-30 2022-07-19 Biois Co.,Ltd Double-stranded nucleic acid signal probe and method for detecting target molecule using same
BR112019001483A2 (pt) 2016-07-27 2019-09-10 Basf Agro Bv método para controlar a vegetação indesejada em um local de cultivo de plantas
US10077465B2 (en) * 2016-09-13 2018-09-18 The United States Of America, As Represented By The Secretary Of The Navy Sorbents for extraction and stabilization of nucleic acids
EP3519093B1 (de) 2016-09-30 2021-03-10 Koninklijke Philips N.V. System zum aufbringen eines reagens auf eine probe
AU2017361521B2 (en) 2016-11-21 2020-08-27 Nanostring Technologies, Inc. Chemical compositions and methods of using same
WO2018114759A1 (en) 2016-12-20 2018-06-28 BASF Agro B.V. Plants having increased tolerance to herbicides
US11891599B2 (en) * 2017-05-22 2024-02-06 Qiagen Healthcare Biotechnologies Systems Gmbh Recovery of nucleic acids from solid supports
US11725200B2 (en) 2017-09-27 2023-08-15 Qiagen Gmbh Method for isolating RNA with high yield
SG11202011274YA (en) 2018-05-14 2020-12-30 Nanostring Technologies Inc Chemical compositions and methods of using same
JP7428657B2 (ja) * 2018-10-26 2024-02-06 テルモ株式会社 標的物質の分離方法および定量方法
WO2020225971A1 (ja) * 2019-05-08 2020-11-12 株式会社日立ハイテク 自動分析装置の前処理方法
US11807909B1 (en) 2019-09-12 2023-11-07 Zymo Research Corporation Methods for species-level resolution of microorganisms
US20220396826A1 (en) * 2019-11-20 2022-12-15 Toray Industries, Inc. Nucleic acid separation method, detection method, nucleic acid purification column and method of producing same
KR20230007464A (ko) 2020-06-05 2023-01-12 주식회사 씨젠 호흡기 병원체 검출을 위한 검체수송 키트 및 이를 이용한 호흡기 병원체 검출방법
KR20220075978A (ko) 2020-11-30 2022-06-08 (주)바이오니아 중저 비유전율을 가진 화합물을 포함한 핵산 결합 완충액을 이용한 핵산 분리방법

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4297337A (en) * 1979-04-13 1981-10-27 Corning Glass Works Solid-phase immunoassays using magnetic glass
US4395271A (en) * 1979-04-13 1983-07-26 Corning Glass Works Method for making porous magnetic glass and crystal-containing structures
US4233169A (en) * 1979-04-13 1980-11-11 Corning Glass Works Porous magnetic glass structure
DE3211309A1 (de) 1982-03-26 1983-09-29 Metin Dipl.-Ing. 6100 Darmstadt Colpan Chromatographisches verfahren zur isolierung von makromolekuelen
US5482834A (en) 1982-05-17 1996-01-09 Hahnemann University Evaluation of nucleic acids in a biological sample hybridization in a solution of chaotrophic salt solubilized cells
US4695393A (en) * 1983-05-12 1987-09-22 Advanced Magnetics Inc. Magnetic particles for use in separations
US4554088A (en) * 1983-05-12 1985-11-19 Advanced Magnetics Inc. Magnetic particles for use in separations
US4672040A (en) 1983-05-12 1987-06-09 Advanced Magnetics, Inc. Magnetic particles for use in separations
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5076950A (en) * 1985-12-20 1991-12-31 Syntex (U.S.A.) Inc. Magnetic composition for particle separation
US6027750A (en) * 1986-09-04 2000-02-22 Gautsch; James Systems and methods for the rapid isolation of nucleic acids
DE3639949A1 (de) 1986-11-22 1988-06-09 Diagen Inst Molekularbio Verfahren zur trennung von langkettigen nukleinsaeuren
US4767670A (en) 1987-01-21 1988-08-30 E. I. Du Pont De Nemours And Company Chromatographic supports for separation of oligonucleotides
ATE117829T1 (de) * 1988-05-24 1995-02-15 Anagen Uk Ltd Magnetisch anziehbare teilchen und herstellungsverfahren.
US5512439A (en) * 1988-11-21 1996-04-30 Dynal As Oligonucleotide-linked magnetic particles and uses thereof
US5075430A (en) * 1988-12-12 1991-12-24 Bio-Rad Laboratories, Inc. Process for the purification of DNA on diatomaceous earth
US5234809A (en) 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
US5523231A (en) 1990-02-13 1996-06-04 Amersham International Plc Method to isolate macromolecules using magnetically attractable beads which do not specifically bind the macromolecules
US5243037A (en) * 1990-09-21 1993-09-07 E. I. Du Pont De Nemours And Company Poly(fluoroalkyl) sugar reagents for surface modification of supports
AU654323B2 (en) 1991-01-04 1994-11-03 Perseptive Biosystems, Inc. Sulfonamide bonded hydrophilic coating
US5155018A (en) * 1991-07-10 1992-10-13 Hahnemann University Process and kit for isolating and purifying RNA from biological sources
US5395498A (en) * 1991-11-06 1995-03-07 Gombinsky; Moshe Method for separating biological macromolecules and means therfor
US5610274A (en) * 1991-11-20 1997-03-11 Cpg, Inc. Production and use of magnetic porous inorganic materials
US5734020A (en) 1991-11-20 1998-03-31 Cpg, Inc. Production and use of magnetic porous inorganic materials
US5346994A (en) * 1992-01-28 1994-09-13 Piotr Chomczynski Shelf-stable product and process for isolating RNA, DNA and proteins
EP0555798B1 (de) 1992-02-13 1999-05-06 Becton, Dickinson and Company Celithydrat und Reinigung von DNS
WO1993025710A1 (en) * 1992-06-08 1993-12-23 Gen-Probe Incorporated Preparation of nucleic acid from mononuclear cells
US5316680A (en) 1992-10-21 1994-05-31 Cornell Research Foundation, Inc. Multimodal chromatographic separation media and process for using same
JP3615545B2 (ja) 1993-02-01 2005-02-02 キアゲン・エヌ・ブイ 第四級アンモニウム塩界面活性剤及びそのｒｎａの単離剤
DE4307262A1 (de) * 1993-03-02 1994-09-08 Christian Bergemann Magnetisches polymeres Siliciumdioxid
ATE256735T1 (de) * 1993-08-30 2004-01-15 Promega Corp Zusammensetzungen und verfahren zur reinigung von nukleinsäuren
US5990301A (en) 1994-02-07 1999-11-23 Qiagen Gmbh Process for the separation and purification of nucleic acids from biological sources
WO1995021177A1 (de) 1994-02-07 1995-08-10 Qiagen Gmbh Verfahren zur herstellung endotoxinfreier oder an endotoxin abgereicherter nucleinsäuren und/oder oligonucleotide für die gentherapie
DE4420732A1 (de) * 1994-06-15 1995-12-21 Boehringer Mannheim Gmbh Vorrichtung zur Behandlung von Nukleinsäuren aus einer Probe
DE59508069D1 (de) * 1994-07-27 2000-04-27 Herbert Pilgrimm Superparamagnetische teilchen, verfahren zur herstellung und deren verwendung
US5582988A (en) 1994-09-15 1996-12-10 Johnson & Johnson Clinical Diagnostics, Inc. Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same
US5652348A (en) 1994-09-23 1997-07-29 Massey University Chromatographic resins and methods for using same
US5660984A (en) * 1994-12-09 1997-08-26 Davis; Thomas E. DNA isolating apparatus comprising a non-porous DNA binding, anion exchange resin and methods of use thereof
DE19520398B4 (de) 1995-06-08 2009-04-16 Roche Diagnostics Gmbh Magnetisches Pigment
JP2965131B2 (ja) * 1995-07-07 1999-10-18 東洋紡績株式会社 核酸結合用磁性担体およびそれを用いる核酸単離方法
US5783686A (en) * 1995-09-15 1998-07-21 Beckman Instruments, Inc. Method for purifying nucleic acids from heterogenous mixtures
SE9600590D0 (sv) 1996-02-19 1996-02-19 Pharmacia Biotech Ab Sätt för kromatografisk separation av peptider och nukleinsyra samt ny högaffin jonbytesmatris
US5904848A (en) 1996-02-21 1999-05-18 Cpg, Inc. Controlled pore glass-synthetic resin membrane
CA2248981C (en) * 1996-03-15 2009-11-24 The Penn State Research Foundation Detection of extracellular tumor-associated nucleic acid in blood plasma or serum using nucleic acid amplification assays
JP3940935B2 (ja) * 1996-06-11 2007-07-04 東洋紡績株式会社 プラスミドｄｎａの抽出精製方法
JPH09327291A (ja) * 1996-06-11 1997-12-22 Toyobo Co Ltd Ｒｎａの抽出精製方法
US6027945A (en) 1997-01-21 2000-02-22 Promega Corporation Methods of isolating biological target materials using silica magnetic particles
DE69810080T2 (de) 1997-01-21 2003-10-09 Grace W R & Co Siliciumdioxidadsorbent auf magnetischem träger
JP4196227B2 (ja) 1997-05-20 2008-12-17 東洋紡績株式会社 核酸またはタンパク質抽出用シリカ粒子組成物
AU3377500A (en) * 1999-02-26 2000-09-14 Myriad Genetics, Inc. Method for extracting dna from dried specimens

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EP0895546A1 (de) 1999-02-10
EP0895546B1 (de) 2003-08-27
DE69817484T2 (de) 2004-06-17
US6673631B1 (en) 2004-01-06
US6027945A (en) 2000-02-22
US20020086326A1 (en) 2002-07-04
DK1367137T3 (da) 2010-07-12
EP0895546A4 (de) 2002-03-20
US6368800B1 (en) 2002-04-09
CA2249393A1 (en) 1998-07-23
JP3253638B2 (ja) 2002-02-04
EP1367137A1 (de) 2003-12-03
AU6647598A (en) 1998-08-07
AU732756B2 (en) 2001-04-26
BR9805897A (pt) 1999-08-24
DE69841555D1 (de) 2010-04-22
EP1367137B1 (de) 2010-03-10
DE69817484D1 (de) 2003-10-02
JPH11509742A (ja) 1999-08-31
WO1998031840A1 (en) 1998-07-23
US20040086930A1 (en) 2004-05-06

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