DE934531T1 - Diagnose spongiformer encephalopathie - Google Patents

Diagnose spongiformer encephalopathie

Info

Publication number
DE934531T1
DE934531T1 DE0934531T DE97909428T DE934531T1 DE 934531 T1 DE934531 T1 DE 934531T1 DE 0934531 T DE0934531 T DE 0934531T DE 97909428 T DE97909428 T DE 97909428T DE 934531 T1 DE934531 T1 DE 934531T1
Authority
DE
Germany
Prior art keywords
encephalopathy
spongiformer
diagnosis
bse
animal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE0934531T
Other languages
English (en)
Inventor
John Collinge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial College of Science Technology and Medicine
Original Assignee
Imperial College of Science Technology and Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26310231&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE934531(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9621469.7A external-priority patent/GB9621469D0/en
Priority claimed from GBGB9621885.4A external-priority patent/GB9621885D0/en
Application filed by Imperial College of Science Technology and Medicine filed Critical Imperial College of Science Technology and Medicine
Publication of DE934531T1 publication Critical patent/DE934531T1/de
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2814Dementia; Cognitive disorders
    • G01N2800/2828Prion diseases
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
DE0934531T 1996-10-15 1997-10-15 Diagnose spongiformer encephalopathie Pending DE934531T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9621469.7A GB9621469D0 (en) 1996-10-15 1996-10-15 Diagnosis
GBGB9621885.4A GB9621885D0 (en) 1996-10-21 1996-10-21 Diagnosis
PCT/GB1997/002843 WO1998016834A1 (en) 1996-10-15 1997-10-15 Diagnosis of spongiform encephalopathy

Publications (1)

Publication Number Publication Date
DE934531T1 true DE934531T1 (de) 2000-04-06

Family

ID=26310231

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69730142T Expired - Lifetime DE69730142T2 (de) 1996-10-15 1997-10-15 Diagnose spongiformer encephalopathie
DE0934531T Pending DE934531T1 (de) 1996-10-15 1997-10-15 Diagnose spongiformer encephalopathie

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69730142T Expired - Lifetime DE69730142T2 (de) 1996-10-15 1997-10-15 Diagnose spongiformer encephalopathie

Country Status (10)

Country Link
US (1) US6998231B2 (de)
EP (1) EP0934531B1 (de)
JP (1) JP2001503141A (de)
AT (1) ATE272842T1 (de)
AU (1) AU4711597A (de)
CA (1) CA2268904A1 (de)
DE (2) DE69730142T2 (de)
ES (1) ES2134749T3 (de)
NZ (1) NZ335290A (de)
WO (1) WO1998016834A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6221614B1 (en) 1997-02-21 2001-04-24 The Regents Of The University Of California Removal of prions from blood, plasma and other liquids
US6617119B2 (en) 1997-02-21 2003-09-09 The Regents Of The University Of California Assay for specific strains of multiple disease related conformations of a protein
US6620629B1 (en) 1997-02-21 2003-09-16 The Regents Of The University Of California Method for detecting prions
AT407160B (de) * 1998-06-04 2001-01-25 Immuno Ag Verfahren zur bestimmung von antigenen
GB2348203B (en) 1998-11-04 2002-06-19 Imp College Innovations Ltd Solube beta-forms of prion proteins, methods of preparation and use
GB9908059D0 (en) * 1999-04-09 1999-06-02 Imp College Innovations Ltd Diagnosis and treatment of diseases
EA007391B1 (ru) 2000-07-07 2006-10-27 Апплайд Резеч Системз Арс Холдинг Н.В. Способ диагностики или выявления конформационного заболевания или его маркера и набор для использования в способе
GB2376071A (en) * 2001-05-31 2002-12-04 Mini Agriculture & Fisheries Method for typing a TSE strain
GB0119339D0 (en) * 2001-08-08 2001-10-03 Medical Res Council Method
GB0125606D0 (en) * 2001-10-25 2001-12-19 Sec Dep For Environment Food & Diagnostic method
GB0227651D0 (en) * 2002-11-27 2003-01-08 Medical Res Council Prion
JP2008505646A (ja) * 2004-07-09 2008-02-28 クロニクス バイオメディカル ウシ海綿状脳症に対するリスクを評価するための核酸の検出法
WO2007150064A2 (en) * 2006-06-23 2007-12-27 Amicus Therapeutics, Inc. METHOD FOR THE TREATMENT OF NEUROLOGICAL DISORDERS BY ENHANCING THE ACTIVITY OF β-GLUCOCEREBROSIDASE
WO2010019270A1 (en) 2008-08-14 2010-02-18 Isis Pharmaceuticals, Inc. Modulation of prion expression

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4892814A (en) 1987-06-22 1990-01-09 The United States Of America As Represented By The Department Of Health And Human Services Method for distinguishing Creutzfeldt-Jakob disease from other dementias
GB9117910D0 (en) * 1991-08-20 1991-10-09 Nat Res Dev Oligonucleotides and their use in an assay
US5789655A (en) 1994-05-13 1998-08-04 The Regents Of The University Of California Transgenic animals expressing artificial epitope-tagged proteins
US5908969A (en) 1994-05-13 1999-06-01 The Regents Of The University Of California Method of detecting prions in a sample and transgenic animal used for same
US6008435A (en) * 1994-05-13 1999-12-28 The Regents Of The University Of California Detecting cow, sheep and human prions in a sample and transgenic mice used for same
US5565186A (en) * 1994-05-13 1996-10-15 The Regents Of The University Of California Method of detecting prions in a sample and transgenic animal used for same
AU3932895A (en) 1994-11-29 1996-06-19 Minister Of Agriculture Fisheries And Food In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland, The Spongiform encephalopathy detection methods
ATE263374T1 (de) * 1995-09-14 2004-04-15 Univ California Für natives prp-sc spezifische antikörper

Also Published As

Publication number Publication date
NZ335290A (en) 2001-08-31
ES2134749T1 (es) 1999-10-16
ATE272842T1 (de) 2004-08-15
CA2268904A1 (en) 1998-04-23
DE69730142T2 (de) 2005-08-11
US20020081645A1 (en) 2002-06-27
EP0934531B1 (de) 2004-08-04
WO1998016834A1 (en) 1998-04-23
ES2134749T3 (es) 2005-03-16
JP2001503141A (ja) 2001-03-06
AU4711597A (en) 1998-05-11
EP0934531A1 (de) 1999-08-11
US6998231B2 (en) 2006-02-14
DE69730142D1 (en) 2004-09-09

Similar Documents

Publication Publication Date Title
ATE272842T1 (de) Diagnose spongiformer encephalopathie
HUP0104890A2 (hu) Eljárás és készlet prion protein extrahálására
DE69729473D1 (de) Pharmazeutisch-genetische verfahren zur verwendung bei der behandlung von krankheiten des nervensystems
BRPI0112262B8 (pt) processo para detecção e teste para um marcador de uma doença conformacional, kit, processo para identificar um composto, processo para detectar a presença de uma forma patogênica prp sc de proteína de príon, e aparelho
ATE440536T1 (de) Verfahren zur diagnose, behandlung und prävention von knochenverlust
DE69738739D1 (de) Verfahren für das Entwerfen von kleinen Erythropoietin Mimetika
ATE443147T1 (de) Sphingosin-1-phosphat-lyase polypeptide, polynukleotide und modulierende mitteln, und verfahren zu deren verwendung
ES2079481T3 (es) Un procedimiento para la determinacion de la actividad funcional de la proteina s o de la proteina c libre en una muestra de plasma.
PT891553E (pt) Metodo de deteccao das encefalopatias espongiformes transmissiveis
CA2364686A1 (en) Prion test
DE69821246D1 (de) Testverfahren für collagenpeptid
ATE415632T1 (de) Verfahren zur diagnose und behandlung von morbus crohn
BR0010007A (pt) Indicadores biológicos para validação de um processo de esterilização de prìon
PT909388E (pt) Ensaios imunologicos para encefalopatias espongiformes
ATE338142T1 (de) Methoden zur diagnose und behandlung von herzkrankheiten
GB2333362A (en) Diagnosis of spongiform encephalopathy
FR2849205B1 (fr) Procede d'amplification de la detection de la prpsc et utilisation d'un ligand adjuvant macrocyclique pour une telle amplification
DK0764273T3 (da) Alfa B crystallin til anvendelse i diagnose og terapi af autoimmune sygdomme, især multipel sklerose
DE60038614D1 (de) Verfahren zur diagnose von synovialen oder osteoartikulären erkrankungen
DE60231106D1 (en) Test für übertragbare spongiforme encephalopathien
DE69940906D1 (de) Verfahren zur untersuchung von krankheiten des zentralen nervensystems und verfahren zum aufsuchen von arzneimitteln
ATE312914T1 (de) Rdgb-proteine
BR0317224A (pt) Processo de detecção de prp (proteìna priÈnio nativa) com uso de um antibiótico dos aminoglicosìdeos
ATE279143T1 (de) Analyse zum nachweis von degenerativen hirnerkrankungen
FI951778A0 (fi) Menetelmä allergian toteamiseksi