EP0056697A3 - Injectable compositions and apparatus suitable for use in inductively heating neoplasms - Google Patents

Injectable compositions and apparatus suitable for use in inductively heating neoplasms Download PDF

Info

Publication number
EP0056697A3
EP0056697A3 EP82300125A EP82300125A EP0056697A3 EP 0056697 A3 EP0056697 A3 EP 0056697A3 EP 82300125 A EP82300125 A EP 82300125A EP 82300125 A EP82300125 A EP 82300125A EP 0056697 A3 EP0056697 A3 EP 0056697A3
Authority
EP
European Patent Office
Prior art keywords
coil
neoplasms
apparatus suitable
injectable compositions
power supply
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP82300125A
Other versions
EP0056697A2 (en
EP0056697B1 (en
Inventor
Robert W. Rand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to AT82300125T priority Critical patent/ATE28128T1/en
Publication of EP0056697A2 publication Critical patent/EP0056697A2/en
Publication of EP0056697A3 publication Critical patent/EP0056697A3/en
Application granted granted Critical
Publication of EP0056697B1 publication Critical patent/EP0056697B1/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5094Microcapsules containing magnetic carrier material, e.g. ferrite for drug targeting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0052Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/40Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • A61N1/403Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals for thermotherapy, e.g. hyperthermia
    • A61N1/406Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals for thermotherapy, e.g. hyperthermia using implantable thermoseeds or injected particles for localized hyperthermia

Abstract

The composition comprises magnetic particles which can undergo hysteresis heating and a pharmacologically acceptable carrier fluid. The particles have thereon an adherent protective coating of pharmacologically acceptable material and/or the carrier fluid is curable in living tissue (e.g. a polymerisable silicone). <??>The apparatus comprises a first induction heating coil with an a.c. power supply (30,32), and at least one further coil (12) provided adjacent and in axial alignment with the first coil. The further coil is electrically isolated from the power supply and connected to form a resonant circuit (26) arranged to resonate when alternating current is passed through the first coil so as to provide additional induction heating.
EP82300125A 1981-01-09 1982-01-11 Injectable compositions suitable for use in inductively heating neoplasms Expired EP0056697B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT82300125T ATE28128T1 (en) 1981-01-09 1982-01-11 INJECTABLE SUBSTANCES FOR INDUCTIONAL HEATING OF MALIGNANT TISSUE FORMATIONS.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/223,727 US4392040A (en) 1981-01-09 1981-01-09 Induction heating apparatus for use in causing necrosis of neoplasm
US223727 1981-01-09

Related Child Applications (2)

Application Number Title Priority Date Filing Date
EP86111207A Division EP0208338A3 (en) 1981-01-09 1982-01-11 Induction heating apparatus
EP86111207.6 Division-Into 1986-08-13

Publications (3)

Publication Number Publication Date
EP0056697A2 EP0056697A2 (en) 1982-07-28
EP0056697A3 true EP0056697A3 (en) 1984-09-19
EP0056697B1 EP0056697B1 (en) 1987-07-08

Family

ID=22837751

Family Applications (2)

Application Number Title Priority Date Filing Date
EP86111207A Withdrawn EP0208338A3 (en) 1981-01-09 1982-01-11 Induction heating apparatus
EP82300125A Expired EP0056697B1 (en) 1981-01-09 1982-01-11 Injectable compositions suitable for use in inductively heating neoplasms

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP86111207A Withdrawn EP0208338A3 (en) 1981-01-09 1982-01-11 Induction heating apparatus

Country Status (11)

Country Link
US (1) US4392040A (en)
EP (2) EP0208338A3 (en)
JP (1) JPS57136463A (en)
AT (1) ATE28128T1 (en)
AU (1) AU557749B2 (en)
BR (1) BR8205337A (en)
CA (1) CA1203851A (en)
DE (1) DE3276683D1 (en)
IL (1) IL64735A0 (en)
MX (1) MX151204A (en)
WO (1) WO1982002339A1 (en)

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JP3398172B2 (en) * 1993-04-09 2003-04-21 電気興業株式会社 Heating temperature control method and high frequency induction heating temperature control device in high frequency induction heating
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AT401348B (en) * 1994-07-12 1996-08-26 Kutschera Josef Coil arrangement for generating a travelling electromagnetic field for therapeutic purposes
AUPP008197A0 (en) * 1997-10-29 1997-11-20 Paragon Medical Limited Improved targeted hysteresis hyperthermia as a method for treating diseased tissue
US7731648B2 (en) * 2001-07-25 2010-06-08 Aduro Biotech Magnetic nanoscale particle compositions, and therapeutic methods related thereto
US7951061B2 (en) * 2001-07-25 2011-05-31 Allan Foreman Devices for targeted delivery of thermotherapy, and methods related thereto
US6997863B2 (en) * 2001-07-25 2006-02-14 Triton Biosystems, Inc. Thermotherapy via targeted delivery of nanoscale magnetic particles
US7074175B2 (en) 2001-07-25 2006-07-11 Erik Schroeder Handy Thermotherapy via targeted delivery of nanoscale magnetic particles
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US6956189B1 (en) 2001-11-26 2005-10-18 Illinois Tool Works Inc. Alarm and indication system for an on-site induction heating system
US8038931B1 (en) 2001-11-26 2011-10-18 Illinois Tool Works Inc. On-site induction heating apparatus
US6713737B1 (en) 2001-11-26 2004-03-30 Illinois Tool Works Inc. System for reducing noise from a thermocouple in an induction heating system
US7015439B1 (en) 2001-11-26 2006-03-21 Illinois Tool Works Inc. Method and system for control of on-site induction heating
US20040084443A1 (en) * 2002-11-01 2004-05-06 Ulrich Mark A. Method and apparatus for induction heating of a wound core
US6911089B2 (en) 2002-11-01 2005-06-28 Illinois Tool Works Inc. System and method for coating a work piece
US20040156846A1 (en) * 2003-02-06 2004-08-12 Triton Biosystems, Inc. Therapy via targeted delivery of nanoscale particles using L6 antibodies
ATE491463T1 (en) 2003-02-20 2011-01-15 Univ Connecticut Health Ct METHOD FOR PRODUCING ALPHA (2) MACROGLOBULIN-ANTIGEN MOLECULE COMPLEXES
US20050230379A1 (en) * 2004-04-20 2005-10-20 Vianney Martawibawa System and method for heating a workpiece during a welding operation
US20050251234A1 (en) 2004-05-07 2005-11-10 John Kanzius Systems and methods for RF-induced hyperthermia using biological cells and nanoparticles as RF enhancer carriers
US7510555B2 (en) 2004-05-07 2009-03-31 Therm Med, Llc Enhanced systems and methods for RF-induced hyperthermia
US7422709B2 (en) * 2004-05-21 2008-09-09 Crosby Gernon Electromagnetic rheological (EMR) fluid and method for using the EMR fluid
US20090081122A1 (en) * 2005-05-23 2009-03-26 Universite De Geneve Injectable superparamagnetic nanoparticles for treatment by hyperthermia and use for forming an hyperthermic implant
US20130153440A9 (en) * 2006-11-13 2013-06-20 Kc Energy, Llc Rf systems and methods for processing salt water
EP2868299B1 (en) 2009-08-24 2022-08-10 New Phase Ltd Phase change and shape change materials
US8565892B2 (en) * 2009-10-31 2013-10-22 Qteris, Inc. Nanoparticle-sized magnetic absorption enhancers having three-dimensional geometries adapted for improved diagnostics and hyperthermic treatment
US20110144546A1 (en) * 2009-12-11 2011-06-16 David Wayne Crothers Heated simulated rock for massage therapeutic use
CN104066450A (en) * 2011-09-28 2014-09-24 韦克森林大学 Compositions for RF ablation
DE102012013534B3 (en) 2012-07-05 2013-09-19 Tobias Sokolowski Apparatus for repetitive nerve stimulation for the degradation of adipose tissue by means of inductive magnetic fields
TWI584777B (en) * 2014-08-22 2017-06-01 國立成功大學 Flexible deep magnetic field generating apparatus
CN107206082B (en) 2014-11-25 2022-01-11 纽菲斯有限公司 Phase-change nanoparticles
US11491342B2 (en) 2015-07-01 2022-11-08 Btl Medical Solutions A.S. Magnetic stimulation methods and devices for therapeutic treatments
US10478634B2 (en) * 2015-07-01 2019-11-19 Btl Medical Technologies S.R.O. Aesthetic method of biological structure treatment by magnetic field
US20180001107A1 (en) 2016-07-01 2018-01-04 Btl Holdings Limited Aesthetic method of biological structure treatment by magnetic field
US10695575B1 (en) 2016-05-10 2020-06-30 Btl Medical Technologies S.R.O. Aesthetic method of biological structure treatment by magnetic field
US11266850B2 (en) 2015-07-01 2022-03-08 Btl Healthcare Technologies A.S. High power time varying magnetic field therapy
US11253717B2 (en) 2015-10-29 2022-02-22 Btl Healthcare Technologies A.S. Aesthetic method of biological structure treatment by magnetic field
US11247039B2 (en) 2016-05-03 2022-02-15 Btl Healthcare Technologies A.S. Device including RF source of energy and vacuum system
US11464993B2 (en) 2016-05-03 2022-10-11 Btl Healthcare Technologies A.S. Device including RF source of energy and vacuum system
US11534619B2 (en) 2016-05-10 2022-12-27 Btl Medical Solutions A.S. Aesthetic method of biological structure treatment by magnetic field
US10583287B2 (en) 2016-05-23 2020-03-10 Btl Medical Technologies S.R.O. Systems and methods for tissue treatment
US10556122B1 (en) 2016-07-01 2020-02-11 Btl Medical Technologies S.R.O. Aesthetic method of biological structure treatment by magnetic field
US11813018B2 (en) 2018-12-18 2023-11-14 Boston Scientific Scimed, Inc. Devices and methods for inducing ablation in or around occluded implants
EP3721939B1 (en) 2019-04-11 2022-07-06 BTL Healthcare Technologies a.s. Device for aesthetic treatment of biological structures by radiofrequency and magnetic energy
US11878167B2 (en) 2020-05-04 2024-01-23 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
KR20230000081U (en) 2020-05-04 2023-01-10 비티엘 헬쓰케어 테크놀로지스 에이.에스. Device and method for unattended treatment of patients
US11896816B2 (en) 2021-11-03 2024-02-13 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient

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Publication number Priority date Publication date Assignee Title
DE523823C (en) * 1931-04-28 Hirsch Kupfer Und Messingwerke Coil for induction furnaces, consisting of a conductive and a heat dissipating part
US1873808A (en) * 1930-03-03 1932-08-23 Edgar L Bailey Means for heating a conductive body
FR750400A (en) * 1932-05-06 1933-08-09 Ugine Infra Device for power factor compensation of induction furnaces
FR1244347A (en) * 1959-09-07 1960-10-28 Acec Induction heating method and device
US3279996A (en) * 1962-08-28 1966-10-18 Jr David M Long Polysiloxane carrier for controlled release of drugs and other agents
DE1284528B (en) * 1967-03-08 1968-12-05 Foerster Device for the elimination of biological tissue by inductively heated bodies with temperature stabilizing properties
US3543762A (en) * 1968-02-15 1970-12-01 Dynapower Systems Corp Of Cali Automatic control of electrotherapeutic apparatus
US3638657A (en) * 1969-07-30 1972-02-01 Hal C Mettler Short wave diathermy circuit
FR2160410A1 (en) * 1971-11-20 1973-06-29 Schering Ag
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FR2291773A1 (en) * 1974-11-20 1976-06-18 Fragnet Jean HF emitter for medical use - has maximum output safety device with cutout meter
US4106488A (en) * 1974-08-20 1978-08-15 Robert Thomas Gordon Cancer treatment method
EP0040512A1 (en) * 1980-05-19 1981-11-25 Corning Glass Works Ceramic suitable for inducing localised heating in the presence of a radio frequency magnetic field, and use thereof

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Patent Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE523823C (en) * 1931-04-28 Hirsch Kupfer Und Messingwerke Coil for induction furnaces, consisting of a conductive and a heat dissipating part
US1873808A (en) * 1930-03-03 1932-08-23 Edgar L Bailey Means for heating a conductive body
FR750400A (en) * 1932-05-06 1933-08-09 Ugine Infra Device for power factor compensation of induction furnaces
FR1244347A (en) * 1959-09-07 1960-10-28 Acec Induction heating method and device
US3279996A (en) * 1962-08-28 1966-10-18 Jr David M Long Polysiloxane carrier for controlled release of drugs and other agents
DE1284528B (en) * 1967-03-08 1968-12-05 Foerster Device for the elimination of biological tissue by inductively heated bodies with temperature stabilizing properties
US3543762A (en) * 1968-02-15 1970-12-01 Dynapower Systems Corp Of Cali Automatic control of electrotherapeutic apparatus
US3638657A (en) * 1969-07-30 1972-02-01 Hal C Mettler Short wave diathermy circuit
FR2160410A1 (en) * 1971-11-20 1973-06-29 Schering Ag
US4106488A (en) * 1974-08-20 1978-08-15 Robert Thomas Gordon Cancer treatment method
LU71825A1 (en) * 1974-11-07 1975-06-24
FR2291773A1 (en) * 1974-11-20 1976-06-18 Fragnet Jean HF emitter for medical use - has maximum output safety device with cutout meter
EP0040512A1 (en) * 1980-05-19 1981-11-25 Corning Glass Works Ceramic suitable for inducing localised heating in the presence of a radio frequency magnetic field, and use thereof

Also Published As

Publication number Publication date
WO1982002339A1 (en) 1982-07-22
EP0208338A2 (en) 1987-01-14
MX151204A (en) 1984-10-09
AU7912481A (en) 1982-07-15
CA1203851A (en) 1986-04-29
EP0208338A3 (en) 1987-05-13
DE3276683D1 (en) 1987-08-13
US4392040A (en) 1983-07-05
ATE28128T1 (en) 1987-07-15
EP0056697A2 (en) 1982-07-28
BR8205337A (en) 1982-12-14
AU557749B2 (en) 1987-01-08
EP0056697B1 (en) 1987-07-08
JPS57136463A (en) 1982-08-23
IL64735A0 (en) 1982-03-31

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